• Journal of Marine Life Science
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• v.7 no.2
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• pp.129-138
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• 2022

Crucian carp, Carassius carassius (Weight 42.4 ± 9.0 g, Length 15.0 ± 1.0 cm) were exposed to waterborne zinc at 0, 5, 10, 20, 40 and 80 mg Zn²⁺/l for 96 hours. The lethal concentration 50 (LC₅₀) at 96 hours of crucian carp, C. carassius exposed to waterborne zinc was 51.58 mg Zn²⁺/l. In hematological parameters, the RBC count was significantly decreased in the concentration of 40 mg Zn²⁺/l at 48 hours, whereas the hematocrit was significantly increased by zinc exposure. The MCV (mean corpuscular volume) (µl) and MCH (mean corpuscular hemoglobin) (pg) were significantly increased in the concentration of 40 mg Zn²⁺/l at 48 hours. The plasma components such as calcium, magnesium, glucose, cholesterol, total protein and ALT (Alanine aminotransminase) were significantly changed by zinc exposure. The results of this study suggest that the zinc exposure to C. carassius induced the significant physiological changes in the hematological parameters and plasma components as toxicity.

• Journal of Institute of Control, Robotics and Systems
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• v.8 no.12
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• pp.1061-1065
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• 2002

Sensors need to be implanted to obtain necessary information for LVAS (Left Ventricular Assist System) operations. Size of the sensors can prevent them from being implanted in a patient and reliabilities of the sensors are questionable for a long term use. In this wort we utilize a developed pump model to estimate flow and pressure difference across the pump without implanted sensors and present a method to obtain the physiological variables as aorta pressure and left ventricle pressure from the pump model and pulsatility of flow estimate or pressure difference estimate. These estimated variables can be used for LVAS control as an index or indices.

• Journal of the Ergonomics Society of Korea
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• v.6 no.2
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• pp.39-40
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• 1987

봉제산업의 꽃이라 불리울 만큼 비중을 크게 차지하는 미싱사들의 신발 설계는 미싱 작업동작에서 나타나는 인간요소의 특성에 적합하도록 최적화되어야 한다. 현재 미싱사들이 착화하고 있는 신발설계구조는 미싱 작업동작 특성으로 나타나는 제 요인을 고려하지 아니한 신발로서 작업능률을 저하시키고 있는 실태이다. 본 연구에서는 설계조건에 따라 다르게 나 타나는 요인의 변수를 인간공학적인 방법으로 조사연구하여 미싱 작업동작에 원활을 기할수 있는 생체원칙에 따라 동적작업과는 다르게 생체내의 6수분과 혈액이 발부위로 몰려 발의 체 적이 팽대해지고 미싱 동작을 시작하여 약10분이 경과되면 생리적 이상으로 1$cm^{2}$당 18 개의 봉제화의 설계시방 기초를 마련하는데 목적이 있다.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.37 no.3
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• pp.229-235
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• 2013

To investigate the effect of the flexible artery wall on the blood flow, three-dimensional numerical simulations were carried out for analyzing the time-dependent incompressible flows of Newtonian fluids constrained by a flexible wall. The Navier-Stokes equations for fluid flow were solved using the P2P1 Galerkin finite element method, and mesh movement was achieved using an arbitrary Lagrangian-Eulerian formulation. The Newmark method was employed for solving the dynamic equilibrium equations for the deformation of a linear elastic solid. To avoid complexity due to the necessity of additional mechanical constraints, we used a combined formulation that includes both the fluid and structure equations of motion to produce a single coupled variational equation. The results showed that the flexibility of the carotid wall significantly affects flow phenomena during the pulse cycle. The flow field was also found to be strongly influenced by the bifurcation angle.

• Journal of the Korean Society of Radiology
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• v.18 no.3
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• pp.275-282
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• 2024

This study analyzed the factors that influence the development of gynecomastia by comparing blood test results and lifestyle between patients diagnosed with gynecomastia and normal control group. Independent sample t-test and chi-square tests were conducted to examine the mean differences among risk factors, and logistic regression analysis was used to calculate the relative risk ratio of various predictors influencing the development of gynecomastia. Age, HGB, HCT, TC, glucose, ALT, alcohol consumption, hair loss medication and medication for benign prostatic hyperplasia were identified as significant variables. Notably, the use of hair loss medication showed the highest univariate odds ratio of 15.79, while HGB decreased by a factor of 0.37. These results suggest that these could play a significant role in the onset of gynecomastia and could serve as foundational data for future diagnosis and management of the condition.

• Journal of the Korean Society of Radiology
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• v.11 no.3
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• pp.131-137
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• 2017

This study investigated the risk factor of Gallbladder stone in Busan and Kyungnam area. The subjects of the experiment was performed with patients by abdominal ultrasonography among the patients who came to the P hospital from June 2016 to December 2016. Among them, risk factors were analyzed on 353 people at the same time when abdominal ultrasonography and hematological test. The statistical analysis of risk factors related to the Gallbladder stone was performed by independent t-test and chi-square test. In consider of difference verification result for calculations odds ratio about independent variables, multiple logistic regression analysis to conduct verify adequacy by calculating forecasting model from variable. As a result, Gallbladder stone risk factors have relevance to age ${\gamma}GTP$ with probability model and values to calculated. Age was showed sensitivity 49.7%, specificity 82.2%, receiver operating characteristic area under curve 0.724. Forecasting probability sensitivity 69.3%, specificity 62.4%, receiver operating characteristic area under curve 0.699 showed, ${\gamma}GTP$ confirmed validity of forecasting model.

• Journal of Yeungnam Medical Science
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• v.9 no.1
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• pp.29-43
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• 1992

A case-control study was conducted to investigate the association between the risk of cancer and selenium concentration in blood and toenails. Seventy three patients and two hundreds eighty three controls were, selected at the Yeungnam University Hospital between May and September in 1991. The selected cases were patients who had been hospitalized for stomach or colon cancer at the Depertment of General Surgery. The controls were people who visited to check physical examination at the Automated Mediscreening Center. The selenium concentration in whole blood and toenails were measured by atomic absorption spectrophotometer equipped with graphite furnace atomizer. The following information was ascertained for all cancer patients and controls : sex, age, body mass index, blood pressure, total serum cholesterol, and history of smoking and drinking. The mean selenium concentration in blood and toenail for all cancer patients were $143.6{\pm}10.8{\mu}g/l$ and $1.04{\pm}0.62{\mu}g/g$ and for the controls, $167.0{\pm}14.5{\mu}g/l$ and $1.15{\pm}0.55{\mu}g/g$, respectively. The difference in blood and toenail selenium concentrations of the two cancer sites was not statistically significant. Metastasis did not influence the concentration of selenium in blood and toenails. In the multiple logistic regression analysis, the blood selenium concentration($_aOR$: 0.888, 95% CI : 0.860-0.918), age, BMI and total serum cholesterol were significant variables for risk of cancer, but the selelenium concentration in toenail was not shown to be a significant variable in this regression analysis. The coefficient for blood selenium concentration adjusted for age, sex, diastolic blood pressure, total serum cholesterol, body mass index and smoking was -0.1184(p<0.01). These findings suggest that low selenium concentration is associated with gastrointestinal cancers. Further epidemiologic studies including important variables such as other antioxidant micronutrients will be necessary.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.47 no.1
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• pp.56-61
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• 2010

Hemorrhagic shock is a common cause of death in the emergency department. The purpose of this study was to investigate the relationship between blood loss as a percent of the total estimated blood volume (% blood loss) and changes in several physiological parameters. The other goal was to achieve an accurate prediction of percent blood loss for hemorrhagic shock in rats using a linear regression model. We allocated 60 Sprague-Dawley rats into four groups: 0ml, 2ml, 2.5ml, 3 mL/100 g during 15 min. We analyzed the heart rate, systolic and diastolic blood pressure, respiration rate, and body temperature in relation to the percent blood loss. We generated a linear regression model predicting the percent blood loss using a randomly chosen 360 data set and the R-square value of the model was 0.80. Root mean square error of the tested 360 data set using the linear regression was 5.7%. Even though the linear regression model is not directly applicable to clinical situation, our method of predicting % blood loss could be helpful in determining the necessary fluid volume for resuscitation in the future.

• Korean Chemical Engineering Research
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• v.57 no.4
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• pp.475-483
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• 2019

Special chemical warfare agents are lethal gases that attack the human respiratory system. One of such gases are blood agents that react with the irons present in the electron transfer system of the human body. This reaction stops internal respiration and eventually causes death. The molecular sizes of these agents are smaller than the pores of an activated carbon, making chemical adsorption the only alternative method for removing them. In this study, we carried out a Computational Fluid Dynamics simulation by passing a blood agent: cyanogen chloride gas through an SG-1 gas mask canister developed by SG Safety Corporation. The adsorption bed consisted of a Silver-Zinc-Molybdenum-Triethylenediamine activated carbon impregnated with copper, silver, zinc and molybdenum ions. The kinetic analysis of the chemical adsorption was performed in accordance with the test procedure for the gas mask canister and was validated by the kinetic data obtained from experimental results. We predicted the dynamic behaviors of the main variables such as the pressure drop inside the canister and the amount of gas adsorbed by chemisorption. By using a granular packed bed instead of the Ergun equation that is used to model porous materials in Computational Fluid Dynamics, applicable results of the activated carbon were obtained. Dynamic simulations and flow analyses of the chemical adsorption with varying gas flow rates were also executed.

• Journal of the Korean Society of Radiology
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• v.13 no.3
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• pp.349-357
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• 2019

The purpose of this study was to evaluate the clinical significance of ultrasonographic classification of fatty liver in three grades. From June 2018 to April 2019, 1047 patients (818 males and 229 females) diagnosed as fatty liver among 3607 patients who underwent abdominal ultrasonography at Busan screening center. Ultrasonography was classified into three grades: Grade I (mild fatty liver), Grade II (moderate fatty liver), and Grade III (severe fatty liver) according to the degree of parenchyma texture, acoustic attenuation, Obesity index, hematological test, and metabolic syndrome. The average age of men in each sex increased with the increase of the fatty liver. Body mass index (BMI) and waist circumference were significantly increased in both men and women (p=.000). hematological analysis showed that AST, ALT, ${\gamma}-GTP$, TG, fasting blood sugar, and glycated hemoglobin were significantly different from each other (p<.05). In women, ALT, ${\gamma}-GTP$ and TG showed a significant difference with increasing fatty liver (p<.05). The prevalence of metabolic syndrome was significantly increased in both sexes as the grade of fatty liver increased (p=.000). Based on the results of this study, it is suggested that the use of ultrasound - guided fatty liver according to severity may be useful for the treatment and follow - up of fatty liver if the liver grade is divided in consideration of hematological variables and metabolic syndrome.