Browse > Article
http://dx.doi.org/10.7742/jksr.2019.13.3.349

Clinical Usefulness of Ultrasonography in the Diagnosis of Fatty Liver  

An, Hyun (Department of Radiology, Inje University Busan Paik Hospital)
Lee, Hyo Yeong (Department of Radiological Science, Dongeui University)
Publication Information
Journal of the Korean Society of Radiology / v.13, no.3, 2019 , pp. 349-357 More about this Journal
Abstract
The purpose of this study was to evaluate the clinical significance of ultrasonographic classification of fatty liver in three grades. From June 2018 to April 2019, 1047 patients (818 males and 229 females) diagnosed as fatty liver among 3607 patients who underwent abdominal ultrasonography at Busan screening center. Ultrasonography was classified into three grades: Grade I (mild fatty liver), Grade II (moderate fatty liver), and Grade III (severe fatty liver) according to the degree of parenchyma texture, acoustic attenuation, Obesity index, hematological test, and metabolic syndrome. The average age of men in each sex increased with the increase of the fatty liver. Body mass index (BMI) and waist circumference were significantly increased in both men and women (p=.000). hematological analysis showed that AST, ALT, ${\gamma}-GTP$, TG, fasting blood sugar, and glycated hemoglobin were significantly different from each other (p<.05). In women, ALT, ${\gamma}-GTP$ and TG showed a significant difference with increasing fatty liver (p<.05). The prevalence of metabolic syndrome was significantly increased in both sexes as the grade of fatty liver increased (p=.000). Based on the results of this study, it is suggested that the use of ultrasound - guided fatty liver according to severity may be useful for the treatment and follow - up of fatty liver if the liver grade is divided in consideration of hematological variables and metabolic syndrome.
Keywords
Ultrasonography; Fatty liver; Obesity indices; Metabolic syndrome;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Nation Cholesterol Education Program : Executive summary of the third report of the National cholesterol education program(NCEP) expert panel on detection, "evaluation and treatment of high blood cholesterol adults(adult treatment panel III)," The Journal of the American Medical Association(JAMA), Vol. 285, No. 19, pp. 2486-2497, 2001.   DOI
2 WHO, "West pacific Region The Asia-Pacific perspective redefining obesity and its treatment," The International Obesity Task Force(IOTF), 2000.
3 J. Y. Seo, B. Y. Cheon, H. J. Yoon, K. E. Lee, S. S. Lee, "The Prevalence Rate of Fatty Liver and Its Risk Factors of Adult Women in a Rural Area", Journal of Epidemiology and Health, Vol. 25, No. 2, pp. 100-7, 2003
4 S. H. Seo, H. O. Lee, H. W. Park, B. K. Jang, U. J. Jung, K. S. Park, "Prevalence and associated factors of nonalcoholic fatty Liver disease in the health screen examinees", The Korean Journal of Internal Medicine, Vol. 70, No. 1, pp. 26-32, 2006.
5 The Third Korea National Health and Nutrition Examination Survey (KNHANES III), 2005
6 J. A. Sung, G. Y. Lee, "The Relationship of Body Mass Index, Waist-to-hip Ratio, and Percentage of Body Fat with Metabolic Syndrome in Adults with Fatty Liver", Korean J Health Promotion, Vol. 8, No. 4, pp. 265-271, 2008
7 K. S. Yoon, E. S. Shin, H. S. Park, S. H. Baek, "Factors related to Patients with Fatty Liver," Korean Journal Family Medicine, Vol. 18, No. 12, pp. 1426-1435, 1997.
8 Y. G. Kim, "Clinical Significance of Degree of Fatty Liver Diagnosed by Ultrasonography," Journal of Radiology Science and Technology, Vol. 31, No. 2, pp. 135-140, 2008.
9 P. Petersen, "Fatty liver in patients with moderate alcohol consumption diabetes mellitus and overweight," Scandinavian Journal of Gastoenterology, Vol. 12, No. 7, pp. 781-784, 1977.   DOI
10 S. Y. Kim, K. W. Shim, H. S. Lee, S. H. Lee, H. L. Kim, Y. A. Oh, "The Association of Nonalcoholic Fatty Liver Disease with Metabolic Syndrome," Korean Journal of Family Medicine, Vol. 28, No. 9, pp. 667-674, 2007.
11 H. B. Chae, M. S. Kim, S. M. Park, R. H. Sung, S. J. Youn "Nonalcoholic Fatty Liver Disease : A Spectrum of Clinical and Sonographical Severity," Chungbuk Medical Journal, Vol. 10, No. 1, pp. 43-51, 2000.
12 R. Hultcrantz, N. Gabrielsson, "Patients with persistent elevation of aminotransferases:investigation with ultrasonography, radiomuclide imaging and liver biopsy," Journal of Internal Medicine, Vol. 233, No. 1, pp. 7-12, 1993.   DOI
13 D. L. Kasper, E. Braunwald, A. S. Fauci, S. L. Hauser, D. L. Longo, L. Jameson, K. J. Isselbacher, "Infiltrative, genetic, and metabolic disease affecting the liver" Harrison's Principles of Internal Medicine, 16th ed. New York:McGraw-Hill, 2005.
14 S. H. Park, W. K. Jeon, S. H. Kim, H. J. Kim, D. I. Park, Y. K. Cho, I. K. Sung, C. I. Sohn, D. K. Keum, B. I. Kim, "Prevalence and risk factors of non-alcoholic fatty liver disease among Korean adults," Journal of Gastroenterology Hepatology, Vol. 21, No. 1, pp. 138-143, 2006.   DOI
15 G. C. Farrell, C. Z. Larter, "Nonalcoholic fatty liver disease: from steatosis to cirrhosis", Hepatology, Vol. 43, No. (2 Suppl 1), pp. S99-112, 2006.   DOI
16 Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of the Third Report of the National Cholesterol Education Program(NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults(Adult Treatment Panel III). JAMA 2001;285(19):2486-97.   DOI
17 K. G. Alberti, P. Zimmer, J. Shaw, "The metabolic syndrome-a new worldwide definition", Lancet, Vol. 366, No. 9491, pp. 1059-62, 2005.   DOI
18 C. A. Mittelstaedt, L. M. Vincent, "Abdominal Ultrasound," New York, Churchill Livingstone, pp. 12-13, 1987.
19 Y. G. Kim, "Clinical Significance of Degree of Fatty Liver Diagnosed by Ultrasonography," Journal of Radiology Science and Technology, Vol. 31, No. 2, pp. 135-140, 2008.