• Korean Journal of Environment and Ecology
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• v.33 no.1
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• pp.75-85
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• 2019

The purpose of this study is to understand the vegetation characteristics of ridges (Gyeongsusan-Seonunsan-Gaeipalsan) in the Seonunsan Provincial Park and to establish reference information for the management of the park in the future. We designated 62 plots with the area of $100m^2$ were installed and analyzed them to investigate the vegetation characteristics. The results of community classification based on TWINSPAN showed seven categories of vegetation communities in the surveyed region: Quercus dentata-Deciduous broad-leaved Community, Quercus variabilis-Pinus thunbergii-Quercus serrata Community, Pinus densiflora Community, Deciduous broad-leaved Community-I, Carpinus tschonoskii-Castanea crenata-Quercus aliena Community, Deciduous broad-leaved Community-II, and Carpinus tschonoskii-Carpinus laxiflora Community. In the vegetation of Seonunsan Provincial Park, coniferous trees such as Pinus thunbergii and Pinus densiflora have been gradually losing their population as part of ecological succession to deciduous broad-leaved trees such as Quercus spp., Carpinus tschonoskii, and Carpinus laxiflora. Moreover, Carpinus turczaninowii, Mallotus japonicus, and others were identified as vegetation reflecting the geographical characteristics of the region neighboring the west coast. The estimated age is 30-60 years, and the oldest tree Pinus densiflora is 63-years old. The index of diversity ($100m^2$) was 0.7942 for Carpinus tschonoskii-Carpinus laxiflora Community, 0.8406 for Carpinus tschonoskii-Castanea crenata-Quercus aliena Community, 0.8543 for Quercus dentata-Deciduous broad-leaved Community, 0.9434 for Quercus variabilis-Pinus thunbergii-Quercus serrata Community, 0.9520 for Deciduous broad-leaved Community-I, 0.9633 for Pinus densiflora Community, and 1.0340 for Deciduous broad-leaved Community-II in the ascending order.

• Journal of Life Science
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• v.29 no.1
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• pp.112-117
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• 2019

Herbal medicines are widely used as therapeutic products in many countries. Corni fructus (CF), the dried ripe sarcocarp of Cornus officinalis Sieb. et Zucc (Cornaceae), has been used for thousands of years in traditional medicine and has been reported to be effective for the prevention and treatment of various diseases, such as kidney diseases and diabetes. Recent research on CF has documented a wide spectrum of therapeutic properties, which include anti-inflammatory, ant-oxidative, immunomodulatory, and anti-cancer effects. However, there is no information on its safety. Therefore, in this study, the toxicity of water extract of CF to ICR mice was investigated. The mice received a single dose of water extract of CF (1,000, 2,000, and 5,000 mg/kg of body weight) via the oral route. Mortality, clinical signs, body weight changes, gross findings, and weights of the principal organs after 14 d were then assessed. The results revealed no adverse effects of CF as determined by clinical signs, body weights, or organ weights and no gross pathological findings in any of the treatment groups. These results suggest that the 50% lethal dose and approximated lethal dose of CF extract is over 5,000 mg/kg. The findings provide scientific evidence for the safety of CFs.

• Journal of Korea Water Resources Association
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• v.52 no.5
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• pp.349-360
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• 2019

The purpose of this study is to evaluate the stream flow and water quality (SS, T-N, and T-P) behavior of Nakdong river basin ($23,609.3km^2$) by simulating the dam and weir operation scenarios using SWAT (Soil and Water Assessment Tool). The operation senarios are the simultaneous release for all dam and weirs (scenario 1), simultaneous release for all weirs (scenario 2), and sequential release for the weirs with one month interval from upstream weirs (scenario 3). Before evaluation, the SWAT was calibrated and validated using 11 years (2005-2015) daily multi-purpose dam inflow at 5 locations (ADD, IHD, HCD, MKD, and MYD), multi-function weir inflow at 7 locations (SHW, GMW, CGW, GJW, DSW, HCW, and HAW), and monthly water quality monitoring data at 6 locations (AD-4, SJ-2, EG, HC, MK-4, and MG). For the two dam inflow and dam storage, the Nash-Sutcliffe efficiency (NSE) was 0.56~0.79, and the coefficient of determination ($R^2$) was 0.68~0.90. For water quality, the $R^2$ of SS, T-N, and T-P was 0.64~0.79, 0.51~0.74, and 0.53~0.72 respectively. For the three scenarios of dam and weir release combination suggested by the ministry of environment, the scenario 1 and 3 operations were improved the stream water quality (for T-N and T-P) within the 3 months since the time of release, but it showed the negative effect for 3 months after compared to scenario 2.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.2
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• pp.245-251
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• 2019

This study examined the effects of 2-methoxy-1,4-naphthoquinone (MQ) on the monocyte chemoattractant protein-1 (MCP-1)-induced migration of monocytes, which is an important phenomenon for the body defense and immune response. MQ is a major component extracted from Impatiens balsamina leaves, which have been used for many years in Asian medicine for the treatment of a range of diseases and pain. The cytotoxicity of MQ began to appear at a concentration of $10{\mu}M$, and approximately 50% cytotoxicity was confirmed at $100{\mu}M$. The MCP-1 induced migration of the THP-1 monocyte cell line increased after MQ treatment in a dose dependent manner and the largest increase was observed at $0.1{\mu}M$. The level of cAMP expression decreased after a treatment with $0.1{\mu}M$ MQ. The phosphorylation of extracellular signal-regulated kinases 1/2 (Erk1/2), a key signaling protein involved in the signaling pathway of C-C motif chemokine receptor 2 (CCR2), a receptor for MCP-1, was increased by the simultaneous treatment of $0.1{\mu}M$ MQ. These results show that MQ increases the MCP-1-induced migration of THP-1, decreases the level of cAMP expression, and increases the level of Erk1/2 phosphorylation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.7
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• pp.218-227
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• 2019

This study examined the effects of balance taping therapy on improving knee pain and the obstacles to daily activity in rural elderly women. The research design was a quasi-experimental research using a non-equivalent control group pre-test and post-test design. The data were collected from January 19th to April 14th, 2017. The research subjects included female elderly over 65 years old who visited 12 senior centers located at Y city in rural areas. The participants were composed of 26 people in the experimental group and 28 people in the control group. Data were collected before and 24 hours after balance taping therapy, and the pain and obstacles to daily activity were measured. The collected data were analyzed using the PASW Statistics 23 Program, which included a $X^2-test$, Shapiro-Wilk test, and Mann-Whitney U test. After the intervention, significant differences were observed in the knee pain (Z=-6.658, p<.001) and obstacles to daily activity (Z=-3.466, p=.001). With regard to lower domain variables of the obstacles to daily activity, significant differences in standing up (Z=-2.860, p=.004), daily activity (Z=-2.629, p=.009), walking (Z=-3.868, p<.001), and dressing up (Z=-2.049, p=.040) were observed between the two groups. On the other hand, there were no significant differences in grip (Z=-.542, p=.588) and arm stretching (Z=-.416, p=.678). In conclusion, applying balance taping to rural elderly women clearly decreases the level of knee pain, reduces the obstacles to daily activity, and improves their quality of life.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.37 no.1
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• pp.1-11
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• 2019

This study was conducted to analyze the conservation status by diagnostical methology for the front wall of Jungjeongdang area of Dodong-Seowon. The study was carried out as photogrammetry and mapping - investigation of materials and conservation status - analysis and evaluation of conservation status. The results are as follows. First, in the case of photogrammetry, each photograph was took in superposition, and the distortions of the photographs were corrected and synthesized. Based on this, actual survey drawings of the wall were prepared. Second, in case of material and conservation status, the wall is in the form of Wapyeondam and the material of the head part are tile, mud and lime, and the material of the body part are mud and tile. The mud was mixed with gravel, sand and straw. At the base part, amorphous natural stones and mud were used. The remarkable damage that appears on the wall is erosion of the base part, and some disintegration appears in the body part. There is a biological patina on the head and the base, and vegetation such as lichen is concentrated on the partial body. There was superficial deposit in the head part, and some tiles were broken or lost. Deep fissures are intensively located in some part of the eastern wall. Third, in the case of analysis and evaluation of the conservation status, it is considered that by the erosion of the foundation part and the disintegration of the body part, there is a possibility that physical damage will continue to be applied to the wall, so immediate action is necessary. The distribution of biological patina and vegetation does not appear to cause great problems in the wall, but it is necessary to reduce it in view of aesthetic problems. A cracked or missing tile would need to be replaced, and deep cracks in the eastern wall appear to have been caused by subsidence, and reinforcement of the underground is necessary to prevent further damage.

• Journal of Bio-Environment Control
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• v.28 no.2
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• pp.166-171
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• 2019

This study was conducted to investigate the effect of gaseous chlorine dioxide ($ClO_2$) concentration and treatment method for maintaining marketability in strawberries 'Maehyang' for export. After harvesting strawberry colored with $60{\pm}5%$ of the skin, and the gaseous $ClO_2$ was applied as four treatments in the cold store set with $10^{\circ}C$ which were as follows: i) non-treatment (Control), ii) $0.2mg{\cdot}L^{-1}$ for 30 minutes, iii) $0.4mg{\cdot}L^{-1}$ for 30 minutes, and iv) continuously exposed at $0.4mg{\cdot}L^{-1}$ during the storage period. Weight loss, firmness, soluble solids content, color, incidence of gray mold, and quality grade of strawberries were investigated every 3 days during 16 days storage in cold store. The weight loss was consistently high at $0.2mg{\cdot}L^{-1}\;ClO_2$ treatment, and the weight loss was lower than other treatments when gaseous $ClO_2$ was continuously treated. Firmness was significantly higher at 0.2 and $0.4mg{\cdot}L^{-1}$ $ClO_2$ treatment on the 13th day of storage. Soluble solids content tended to below in continuous gaseous $ClO_2$ treatment. The colors showed no tendency as affected by concentrations and treatment methods of gaseous $ClO_2$. No gray mold was observed in the continuous gaseous $ClO_2$ treatment until the 13th day of storage. The quality grade was lower in gaseous $ClO_2$ treatment group than in the control. As a result, it was possible to decrease the weight loss and the incidence of gray mold by continuously treating the gaseous $ClO_2$ to strawberry 'Maehyang' for export during the storage period after harvest. However, further research is needed on method to maintain quality grades of fruits.

• Journal of Ginseng Culture
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• v.1
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• pp.78-92
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• 2019

Among the Southeast Asian countries, Vietnam had the most cultural exchange with Korea. Through Confusion and Chinese character, which were the common measure for two countries, Korea and Vietnam could communicate and share a sentiment with each other. Two countries showed an enormous interest in each other, and hence they could keep good relationship without official diplomatic relations. During the early 19th century, Korean Ginseng had gained tremendous popularity in Vietnam. Vietnamese believed the stamina of Minh Mang, who had 142 sons and daughters, originated from ginseng. Minh Mang bestowed ginseng on old courtiers for their contribution, which made them more loyal to the king. This tradition was inherited to the future generations, and soldiers who fought with Thai, Cambodia and France also received ginseng for their contribution. In other words, ginseng was the very important key for enforcement of patriotism. Due to the tradition, Korean ginseng has been considered as the premium ginseng in Vietnam. It is presumed that ginseng flew into Vietnam through 4 routes; 1) as an imperial gift from Chinese emperor, 2) by the Vietnamese ambassadors who went to Beijing for a tribute, 3) through private trade and 4) from Ryukyu or Japan, which were the hub of international trade. From 15th to 18th century, ambassadors from Chosun and Vietnam actively interacted in Beijing. Through their interchange, Vietnamese royal family could learn about the value of ginseng. The fact that there were many Shilhak scholars among the ambassadors from Joseon, such as Seo Geojeong and Seo Hosu who had profound knowledge of ginseng proves the theory. It is also possible that reputation of ginseng was already established in Vietnam during Silla period. Ko Byung, an bureaucrat from Tang Dynasty who ruled Vietnam for 10 years in middle 9th century and a friend of Choi Chiwon, might have delivered the knowledge of ginseng to the upper class in Vietnam. This hypothesis, however, should be proven by literatures. Hence, further research about the trace of Korean ginseng in Vietnamese history and literary works still remains to be done.

• Journal of Life Science
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• v.29 no.1
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• pp.18-28
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• 2019

Recent studies reported that obesity upregulated the expression of neuronal nitric oxide synthase (nNOS) and regulated particular behavior patterns in animal models. They also reported that ameliorated the increase in nNOS expression and decreased depression and anxiolytic effects. Thus, exercise seems to be an effective strategy for improving brain function by downregulating nNOS. However, the immune response differs greatly, depending on the exercise intensity. The aim of the present study was to investigate differences in brain nNOS expression in obese C57BL/6 mice that performed exercise of different intensities. Obesity was induced in 6-wks-old mice (n=35) by feeding a 60%-fat diet for 6-wks. A control (CON) group (n=14) was fed a normal diet. At the end of the induction 6-wks period of obesity, seven animals in the CON group and obesity-induced group were sacrificed to confirm obesity induction (preliminary experiments and confirmation of visceral fat accumulation). The remaining animals were then used in an 8-wks exercise intervention. Other than the CON (n=7), the obesity-induced animals were divided into the following groups: high-fat diet (HFD, n=7), HFD-low intensity (HFD-LI, n=7, 12 m/min for 75 min), HFD-moderate intensity (HFD-MI, n=7, 15 m/min for 60 min), and HFD-high intensity (HFD-HI, n=7, 18 m/min for 50 min). The exercise was performed on an animal treadmill. The expression of the nNOS protein in the hippocampus was significantly higher in the HFD group as compared with that in the CON group (p<0.01). However, there was no difference in the hippocampal expression of the nNOS protein in the other exercise groups as compared with that in the CON group. In contrast, nNOS expression in the HFD-HI group was significantly lower than that in the HFD-LI group (p<0.05). The expression of phosphorylated Akt (pAkt) was significantly higher in all the exercise groups as compared with that in the CON and HFD groups. There was no difference in the expression of pAkt in the cerebral cortex among groups, and the expression of pAkt in the cerebellum was significantly higher in the HFD-HI group as compared with that in the CON group (p<0.05). There were also no between-group differences in pAkt expression in the cerebellum among the various exercise groups. In conclusion, nNOS seems to be overexpressed in response to obesity, and it appears to be downregulated by exercise. Relatively high-intensity exercise may be effective in improving brain function by downregulating nNOS.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.2
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• pp.221-233
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• 2019

In Korea, small and medium sized domestic enterprises(SMEs) play an pivotal role in the national economy, accounting for 99.9% of all enterprises, 87.9% of total employment, and 48.3% of production. and SMEs was driving a real force of the development of national economy in many respects such as innovation, job creation, industrial diversity, balanced regional development. Despite their crucial role in the national development, most of SMEs suffer from a lack of R&D capabilities and equipments as well as funding capacity. Public R&D institutes can provide SMEs with valuable supplementary technological knowledge and help them build technological capacity. so, In order to effectively support SMEs, government and public R&D institutes must be a priority to know about the factors influencing the performance related to technology transfer and technological collaborations. In particular, SMEs are not only taking up a large portion of the national economy, but also their influence in politics and economy so strong that raising the competitiveness of small and medium-sized companies is a national policy goal that must be achieved in order to achieve sustained economic growth. For this reason, it is necessary to look specifically at the relationship between concepts such as the environment, strategy, and organizational culture surrounding the enterprise to enhance the competitiveness of SMEs. The paper analyzes 665 companies to find out which organizational culture affects their performance by classification and type of business of SMEs. This study demonstrated that when SMEs seek consistency in their external environment, strategies, and organizational structure to maintain their continued competitiveness. According to three-way analysis of variance (3-way ANOVA) indicates that classification of industries in SMEs has statistically significant main effects, but the type of business and organizational culture do not have significant effects. However, the company's organizational performance (operating profit) of SMES were found to differ significantly in comparison between groups according to classification standards of industries, and therefore adopted some parts. In addition, an analysis of the effect of interaction between the three independent variables of small and medium-sized enterprises has shown that there are statistically significant interaction effects among classification, types of business, and organizational cultures. The results shows that there is an organizational culture suitable for each industry classification and type of business of an entity, and is expected to be used as a basis for establishing promotion policies related to the incubation and commerciality of small and medium-sized venture companies in the future.