• Journal of Life Science
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• v.20 no.10
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• pp.1483-1489
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• 2010

The purpose of this study was to investigate the effects of treadmill exercise and a protein diet on immunoglobulin and antioxidant enzymes in rats. Forty-four male Sprague-Dawley rats, 5 weeks old, were used. Experimental groups were divided into exercise with protein diet group (A, n=11), exercise group (B, n=11), protein diet group (C, n=11), and the control group (D, n=11). Exercise was administered through a treadmill running program (14~18 m/min, $0^{\circ}$ grade, 20 min/day, 5 day/wk) and these rats were given a 40% protein diet for 4 wk. The results of this study are as follows: the protein diet group showed a significant increase in IgG of immunoglobulin compared to the exercise group and control group; the exercise with protein diet group and protein diet group showed a significant increase in SOD activity of antioxidant enzymes compared to the control group; the exercise with protein diet group, exercise group and protein diet group showed a significant increase in GPx activity of antioxidant enzymes compared to the control group; the exercise with protein diet group showed a significant increase in CAT activity of antioxidant enzymes compared to the protein diet group and control group. In conclusion, treadmill exercise and a protein diet were found to help with immunoglobulin and antioxidant enzymes. Further research regarding the effects of exercise and protein diets is required.

• Journal of Life Science
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• v.19 no.10
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• pp.1352-1359
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• 2009

We designed this study to investigate the effects of continuous strenuous aerobic exercise on the respiratory system in a rat model. After exercise for 8 weeks, rats' weights were higher in the exercise groups than in the Control group (non-exercise). Rats in Exercise-120 min group (Ex-120 group) had the lowest weights. Total leukocyte counts in bronchoalveolar lavage fluid (BALF) were higher in exercise groups than in Control group. The Ex-30 and Ex-120 groups had higher neutrophil counts, whereas that in the Ex-60 group was lower than in the Control group, and that in the Ex-30 group was the highest. Lymphocyte and monocyte counts were higher in all exercise groups than in the Control group, and those in the Exercise-120 min group were the highest. Interleukin-6 (IL-6) level was the highest, while IL-10, interferon-$\gamma$ and nitric oxide (NO) levels were the lowest in the Ex-120 group when compared to the Control and other exercise groups. These findings suggest that strenuous aerobic exercise for short periods (30 min) may have a beneficial effect on decrease in body weight, whereas prolonged-strenuous aerobic exercise (>1 hr) may be adverse to leukocyte and immune levels in the bronchoalveolar system, as well as result in an increased production of oxygen free radicals.

• Journal of Oral Medicine and Pain
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• v.38 no.1
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• pp.35-51
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• 2013

The aims of this study was to observed an effect of antioxidative in cardiac muscle of high fat diet induced obesity rat by treadmill exercise with intensity and time. Thirty-two Sprauge-Dawley rats which were divided into four group. Normal, Control(high fat diet induced obesity rat), Experimental I(high intensity intermittent exercise in high fat diet induced obesity rat), Experimental II(moderate intensity endurance exercise in high fat diet induced obesity rat). The results of this study were as follows: 1. In change of body weight, the outcome of each group significantly difference compared with control. Also, 1 to 3 weeks significantly different compared with pre valu experimental I and II(p<0.001). 2. In change of lipid profile, the outcome of each group significantly difference compared with control(p<0.001). Difference between experimental I and II is not significantly. 3. In change of antioxidative enzymes(SOD, CAT, GPx) in myocardium, there are significant difference between control and experimental II, and also between control and experimental I(p<0.001). 4. In change of antioxidative protein MCR-1, the outcome of each group significantly difference compared with control(p<0.01). Experimental II was most significantly difference than the other group(p<0.001). The above results suggest that treadmill exercise effectively reduced in fat. It would be considered that moderate intensity endurance exercise has an effects on improved antioxidative enzyme in cardiac muscle of high fat diet induced obesity rat.

• Proceedings of the Korea Society of Design Studies Conference
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• 2003.05a
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• pp.82-83
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• 2003

• Journal of Life Science
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• v.19 no.3
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• pp.403-410
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• 2009

This study investigated the effects of treadmill exercise on memory ability, cell proliferation, BDNF, and TrkB in the hippocampus and forebrain cholinergic cells in adolescent rats. Male Sprague-Dawley rats (4 weeks old) were randomly assigned to the following two groups: the sedentary group (n=10) and the exercise group (n=10). Rats in the exercise group were forced to run on a treadmill for 30 min, five times per week for 4 weeks. The latency of the step-through avoidance task was used in order to evaluate memory ability. Hippocampal brain-derived neurotrophic factor (BDNF) and tropomyosin-related kinase B (TrkB) expression were assessed by Western blotting. Hippocampal cell proliferation and forebrain cholinergic cells were assessed by immunohistochemistry. The present study showed that treadmill running during the adolescent period significantly improved memory capability, increased hippocampal cell proliferation, up-regulated hippocampal BDNF and TrkB expression, and enhanced the number of forebrain cholinergic cells. These results suggest that regular exercise during the adolescent period may enhance memory function.

• Proceedings of the ESK Conference
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• 1998.04a
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• pp.124-130
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• 1998

본 연구의 목적은 트레드밀 운동시 신체에 가해지는 중량별 부하가 심박수, 환기량, 호흡수, 이산화탄 소배출량, 산소섭취량, 체중당산소섭취량, 호흡교환률 등에 어떠한 영향을 미치는 지를 측정하여 훈련이 나 운동처방에 도움이 될 수 있는 자료를 얻고자 하였다. 피검자들은 성인 남녀 각 5명씩을 대상으로 하였으며, 신체 중량별 부하는 남자에게 안정시, 무부하, 5kg부하, 10kg부하, 15kg무하로 하였으며, 여자 에게는 안정시, 무부하, 5kg부하, 10kg부하로 구분하여 측정하였다. 운동부하는 트레드밀(TC-1200, Technogym, Italy)을 이용하여 중량별로 4km/hr로 3분간 실시하였다. 단계별 운동부하에 의한 인체에 미치는 호흡순환계의 변화를 조사하기 위해 호흡순환계의 변인을 측정 분석한 결과, 다음과 같은 결론 을 얻었다. 남자그룹의 경우는 심박수, 환기량, 이산화탄소배출량, 산소섭취량, 체중당산소섭취량, 호흡 교환률에 대한 중량별 평균차의 검증에서 안정시와 무부하, 5kg부하와 10kg부하, 10kg부하와 15kg부하 사이 에는 유의한 차이가 나타났고, 무부하와 5kg부하 사이에서는 유의한 차이가 없었다. 호흡수에있어서는 10kg 부하와 15kg부하 사이에서만 유의한 변화가 나타났다. 여자그룹의 경우는 심박수, 환기량, 이산화탄소배출 량에 대한 중량별 평균차의 검증에서는 안정시와 무부하, 무부하와 5kg부하, 5kg부하와 10kg부하 사이에서 유의한 변화가 나타났으며, 산소섭취량과 제중당산소섭취량에 있어서는 안정시와 무부하, 무부하와 5kg부하 사이네서만 유의한 변화가 나타났다. 또한 호흡교환률과 호흡수에 있어서는 안정시와 무부하 사이에서만 유의한 변화가 나타났으며, 무부하와 5kg부하, 5kg부하와 10kg부하 사이에는 유의한 차이가 없었다. 이와 같은 결과를 종합해 보면 남자에게는 걷기시에 단계별 무게부하가 호흡순환계에 영향을 미친다고 볼 수 있 으나, 5kg까지의 부하는 호흡순환계에 영향을 미치지 않고 일을 수행할 수 있음을 알 수 있다. 그리고 여자에게는 걷기시에 단계별 무게부하가 운동시 심박수와 환기량, 이산화탄소 배출량에는 영향을 미치고 호흡 교환률과 호흡수에는 영향을 미치지 않음으로보아, 여자에게는 걷기시에 단계별 무게 부하가 호흡순환계에 영향을 받고있음을 알 수 있다.

• Journal of the Korea Convergence Society
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• v.11 no.9
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• pp.297-303
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• 2020

The purpose of this study is to investigate the effects of aerobic exercise and probiotics ingestion on motor learning and body weight in female mice during adolescence. The subjects were divided into six groups of variables, such as non-exercise, moderate, high-intensity exercise, probiotics ingestion, and non-probiotics, and then treated for four weeks. The vertical grid test was conducted before and after the treatment to evaluate motor learning and bodyweight. The high-intensity exercise and probiotics ingestion group showed fastest up, rotation, and down rate than the non-exercise group (p<.001). Also, a group that treated exercise and probiotics tended to record speedier performance than those that performed the only exercise. Comparing weight changes, the weight gain of a group that performed only moderate-intensity exercise was higher than that of a non-probiotics and non-exercise group (p=.032). Taken together, aerobic exercise during adolescence can help improve motor learning, and more efficient motor learning can be achieved when combined with probiotics ingestion.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2008.06a
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• pp.883-884
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• 2008

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.9
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• pp.3834-3842
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• 2011

The purpose of this study is to analyze the kinematic characteristics of children with Down syndrome got congenitally joint laxity and muscle hypotonic. The subjects are boys with Down syndrome and don't have the other disabilities. We got three dimensional position data and then calculated spatiotemporal and kinematic variables during walking on treadmill used increasingly for gait analysis and training. In result, in order to overcome their gait instability due to their musculoskeletal characteristics they walked with hip, knee and ankle joints more flexed than the typical gait pattern, and on the propulsion phase they extend the lower limb joints less than the typical, result in propel the body less than. The reason is that the more is the propulsion by extending the joints, the greater is the reaction force from the ground on heel contact. This result is expected to be used to develop the training program for intensification of musculoskeletal system aim to improve the other musculoskeletal disabilities as well as Down syndrome.

• Journal of the Korea Convergence Society
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• v.12 no.8
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• pp.77-83
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• 2021

The purpose of this study was to determine whether the convergence pulmonary function of the 20s men of mild intellectual disabilities with obesity to tredmill exercise. Ten subjects of mild intellectual disabilities with obesity(experimentals) and ten contrary subjects(controls) were participated in the experiment. experimental group conducted treadmill gait training and control group conducted automed exercise. Subjects were assessed for their respiratory function by using Fit mate. The result of the experiments showed high pulmonary function than the controls. Thus, it suggests that the respiratory functional data of 20s men of mild intellectual disabilities with obesity can be used as a various respiratory one for the exercise programs in the area.