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http://dx.doi.org/10.14476/jomp.2013.38.1.035

The Effect of Antioxidative Change in Cardiac Muscle of Obesity Rat by Treadmill Exercise with Intensity and Time  

Kim, Myung-Hee (Department of Physical Therapy, Graduate School of Dong-Shin University)
Kim, Young-Eok (Department of Physical Therapy, Graduate School of Dong-Shin University)
Yoon, Chang-Lyuk (Department of Oral Medicine, College of Dentistry, Chosun University)
Ryu, Ji-Won (Department of Oral Medicine, College of Dentistry, Chosun University)
Ahn, Jong-Mo (Department of Oral Medicine, College of Dentistry, Chosun University)
Publication Information
Journal of Oral Medicine and Pain / v.38, no.1, 2013 , pp. 35-51 More about this Journal
Abstract
The aims of this study was to observed an effect of antioxidative in cardiac muscle of high fat diet induced obesity rat by treadmill exercise with intensity and time. Thirty-two Sprauge-Dawley rats which were divided into four group. Normal, Control(high fat diet induced obesity rat), Experimental I(high intensity intermittent exercise in high fat diet induced obesity rat), Experimental II(moderate intensity endurance exercise in high fat diet induced obesity rat). The results of this study were as follows: 1. In change of body weight, the outcome of each group significantly difference compared with control. Also, 1 to 3 weeks significantly different compared with pre valu experimental I and II(p<0.001). 2. In change of lipid profile, the outcome of each group significantly difference compared with control(p<0.001). Difference between experimental I and II is not significantly. 3. In change of antioxidative enzymes(SOD, CAT, GPx) in myocardium, there are significant difference between control and experimental II, and also between control and experimental I(p<0.001). 4. In change of antioxidative protein MCR-1, the outcome of each group significantly difference compared with control(p<0.01). Experimental II was most significantly difference than the other group(p<0.001). The above results suggest that treadmill exercise effectively reduced in fat. It would be considered that moderate intensity endurance exercise has an effects on improved antioxidative enzyme in cardiac muscle of high fat diet induced obesity rat.
Keywords
Antioxidative; Cardiac muscle; Obesity; Treadmill exercise;
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