• Title/Summary/Keyword: 코호트연구

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Analyzing association between low-density lipoprotein reduction by statin and adherence to medication using national health insurance service-national sample cohort (NHIS-NSC) (표본코호트기반 고지혈증 약제의 저밀도 콜레스테롤 감소량 및 투약순응도 분석)

  • Kim, Kyu-Jin;Jun, Chi-Hyuck;Lee, Hyeseon;Kim, Hun-Sung
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.5
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    • pp.1027-1041
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    • 2017
  • Hyperlipidemia, the status of blood with high level of low-density lipoprotein cholesterol (LDL-C), is known as a main cause of coronary artery diseases such as myocardiac infarction or brain infarct. Statin is the representative prescription to hyperlipidemia and the effects of it depend on the patient's individual conditions such as health-caring habits or adherence to medication. The main effect of statin is reducing LDL-C, which should reach the target range based on National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) guideline. In this research, the reduction of LDL-C and attainment to patient's target range are considered effects of statin. The association between factors - individual conditions and adherence to medication of patients - and the effects of statin is analyzed with National Health Insurance Service-National Sample Cohort (NHIS-NSC).

Predictors of self-worth and self-deprecation trajectories among Korean adolescents (우리나라 청소년의 긍정적 자아존중감과 부정적 자아존중감의 변화궤적과 예측요인)

  • Yoo, Changmin
    • Journal of the Korean Society of Child Welfare
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    • no.59
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    • pp.25-58
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    • 2017
  • This study aimed to identify self-worth and self-deprecation trajectories and their associated factors among Korean adolescents. For these purposes, we used latent growth curve modeling involving 2,350 students who participated in the Korea Children and Youth Panel Survey in 2010, 2012, 2014, and 2015. Major findings are as follows: 1) Adolescents' self-worth and self-deprecation increased with time, but the speed gradually changed to a quadratic function model; and 2) the types of predictors affecting self-worth and self-deprecation were different. Specifically, the factors that affected only self-worth were adolescents' relationship with teachers and household income, and the factors that affected only self-deprecation were presence of disease and parental over interference. Factors affecting both self-worth and self-deprecation were child's sex, parental affection, peer trust, and peer alienation. These results suggest that independent intervention is needed for self-worth and self-deprecation. Furthermore, the results can be an important basis for establishing a more focused intervention strategy when intervening in self-worth and self-deprecation in adolescents.

A Cohort study on the relationship between pesticide use and mortality, and cancer mortality (농약사용과 사망률과의 관계에 대한 코호트연구)

  • Oh, Hee-Chul;Nam, Chung-Mo;Lee, Sun-Hee
    • Journal of Preventive Medicine and Public Health
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    • v.24 no.3 s.35
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    • pp.390-399
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    • 1991
  • The purpose of this study is to examine the relationship between pesticide use and mortality, and cancer mortality which are recognized as health hazards of pesticides. Data were analyzed from a cohort of 6,066 people aged fifty-five or over and who have been residing in the main island of Kangwha county. Death certificates, computerized citizenship registers searches, and household interview survey lead to get more than ninety-seven percents follow-up rate for the first five year observation period. Important findings are as follows : 1. Age specific mortality rates of pesticide users are significantly lower than those of pesticides nonusers. The SMR of male is 0.80, and 0.58 for females respectively probably due to healthy worker effects. But, age specific cancer mortality rates are significantly higher than those of pesticide nonusers (SMR=1.59) in males. This finding is not observed in females (SMR=0.85), however. 2. Logistic regression analyses showed that self-reported health status, drinking, and smoking histories in male are significantly associated with total mortality rate. The histories of pesticide use are also calculated to be highly associated with cancer mortality as in univariate analyses in males. In female, self-reported health status, age of first delivery are found to be significantly related to total mortality rate. Only drinking history is calculated to be associated with cancer mortalities in females. Data from further observation of 'Kangwha cohort' and indepth analyses of these are highly expected.

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Cohort Study on the Association between Alcohol Consumption and the Risk of Colorectal Cancer in the Korean Elderly (노인인구에서 음주와 대장직장암 발생간의 연관성에 관한 코호트연구)

  • Lim, Hoi-Jeong;Park, Byung-Joo
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.1
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    • pp.23-29
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    • 2008
  • Objectives : We examined the association between alcohol consumption and incidence of colorectal cancer in elderly Koreans. Methods : The cohort members (n=14,304) consisted of 4,834 males and 9,470 females derived from the Korea Elderly Pharmacoepidemiologic Cohort (KEPEC), a population-based dynamic cohort. They were aged 65 years old or older and lived in Busan between 1993-1998; they were beneficiaries of the Korean Medical Insurance Corporation (KMIC). Baseline information was surveyed by a self-administered, mailed questionnaire. This study population was restricted to 14,304 participants who reported alcohol drinking habits on the questionnaire and had not been diagnosed with colorectal cancer at baseline. The adjusted hazard ratios (aHR) of status, type, frequency and daily average amount of alcohol consumption were computed with Cox's proportional hazard model, with the never-drinkers as a reference group and controlling for age and gender. Results : After 4.82 person-years of mean follow-up 112 cases of colorectal cancer occurred. The incidence densities of colorectal cancer were 161 (95% CI=123-200) for never-drinkers, 219 (95% CI=125-339) for ex-drinkers, and 137 (95% CI=84-189) for current-drinkers per 100,000 person-year. The status, type, frequency, and daily average amount of alcohol consumption were not significantly related to the incidence of colorectal cancer after controlling for age and gender. Conclusions : There was no significant association between alcohol consumption and colorectal cancer among elderly people after controlling for age and gender.

Labor Market Integration and Transition to Marriage (노동시장통합과 결혼 이행)

  • Yoon, Ja-Young
    • Korea journal of population studies
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    • v.35 no.2
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    • pp.159-184
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    • 2012
  • This study purports to analyze how individuals' labor market integration affect their transition to marriage. In doing so, I construct variables for job stability and continuity to represent labor market integration using labor force status and years of participation at the time of marriage and during the three years up to the point of marriage. In particular, I focus on differential effects of these labor market integration on the transition to marriage by cohorts: one for those who are likely to enter the labor market after the 1997 financial crisis and the other for those who are before the 1997 financial crisis. I used the Korean Labor and Income Panel Study and analyzed individuals aged above 18 in 2008. The main results are as follows. being currently employed and regular employment increases hazards of the first marriage for men but decreases them for women. long-term no-jobs decreases hazards of marriage for both women and men. long-term regular employment increases hazards of marriage for women but not for men at the statistically significant level. These effects vary by cohorts implying that recent economic and labor market instability deteriorated economic conditions for the youth making transitions to marriage.

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A Comparative Study on Risk Factors Related to Patient with Recurrent Stroke Between Recurrent Group and Non-recurrent Group: Single Hospital Based Cohort Study (뇌졸중 재발자와 비재발자의 뇌졸중 재발 위험 요인의 비교 분석: 일개 병원의 뇌졸중 환자 코호트를 기반으로)

  • Jeon, Mi Yang;Cho, Hyung Je;Park, Mingyeong;Jin, Mi Jeong;Ha, Youngmi
    • Journal of muscle and joint health
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    • v.27 no.3
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    • pp.219-228
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    • 2020
  • Purpose: This study was a comparative analysis of stroke-related factors between recurrent patients and non-recurrent patients. Methods: A retrospective cohort study design was used, and data were collected from March 2020 to April 2020 using electronic medical records. 244 patients (221 first-timers and 23 recurrent) were included in this study. Results: The stroke recurrence rate in 5 years was 9.4%, the readmission rate was 39.3%, and the mortality rate was 2.0%. The number of patients hospitalized for stroke was greater among men than among women. Of the patients, 60.7% had an underlying disease. With regard to daily life abilities, over 70% of participants needed more than moderate dependence and about 40% of participants had more than mild cognitive impairment. More than 50% were moved to wheelchairs or stretcher cars. The difference in the stroke readmission rate between recurrent and non-recurrent patients was statistically significant. Conclusions: Based on our findings, a program to prevent recurrence of stroke should be developed to considering age, ability of daily living, place of discharge, gait ability at discharge, and place of discharge.

생태계 복원사업의 생태${\cdot}$경제 통합체계 동태분석 II;임진강 참게 복원사업의 확장모형을 중심으로

  • Jeong, Hoe-Seong;Jeon, Dae-Uk
    • Proceedings of the Korean System Dynamics Society
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    • 2006.11a
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    • pp.49-69
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    • 2006
  • 본 논문은 선행연구인 정회성${\cdot}$전대욱 (2005)의 모형을 중심으로 선행연구에서 미처 다루지 못한 체계 변화 및 모형 확장 등에 대해 다루고 있다. 선행연구에서는 우리나라의 참게 복원사업에 대한 개체수 동태모형(population dynamics)과 자원 경제학적 이론모형을 근거로 생태${\cdot}$경제 통합시스템에 대한 동태모형을 도출하고 이를 통해 실증분석을 수행하였는데, 본 논문에서는 이 통합 모형에 있어서 밀도 제약(density restriction)과 공식 행위(cannibalistic behavior), 주민참여에 의한 환경개선 등 일련의 가정들에 대한 확장을 통해 보다 일반화된 통합체계 및 시스템 다이내믹스 분석을 제시한다. 이와 같은 모형 확장 및 파라메터의 내생화 등은 관련 피드백 루프들의 변형과 추가 등을 의미하며, 이와 같은 변화를 포함한 확장 모델을 제시하고 분석함으로써 참게 복원사업에 대한 보다 폭넓은 논의를 제시하고자 한다.

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한국사회 자살 통계에 대한 장기 추세 분석: 『경찰통계연보』 1953년~2015년 자살통계를 중심으로

  • Jeong, Seung-Hwa
    • Korean Journal of Social Issues
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    • v.18 no.1
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    • pp.83-125
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    • 2017
  • 이 연구는 유신체제 이후 대외비 문서로 분류되어 학자들 사이에서도 잘 알려지지 않았던 『경찰통계연보』의 자살 통계를 통해 1953년부터 2015년까지의 자살자수와 자살률의 시계열적 변화, 자살원인과 자살수단의 장기적인 변화의 추세를 분석하였다. 자살률의 장기시계열적인 변화를 살펴봄으로써 이 논문은 통계청 자살통계로만 파악했을 때 알려지지 않았던 한국사회 1960~70년대 개발독재시기의 자살률 추이를 분석하였고 이 시기 자살률이 매우 높았음을 논의하였다. 그리고 통계청 자살 통계와 경찰청 자살 통계의 비교 검토를 통해 1999년~2007년까지의 통계청 자살 통계가 수정 보완된 점을 지적하였다. 2000년대 초반 통계청 자살 통계의 급증과 관련한 기존 연구의 분석을 검토하면서 통계 작성의 행정적 변화가 자살 통계에 미친 영향에 대해 논의하였다.

Vitamin D and Depression (비타민 D와 우울증)

  • Cho, Su Kyung;Koo, Sle;Park, Kyong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.10
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    • pp.1467-1476
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    • 2014
  • Recent studies have shown that insufficient or deficient vitamin D status may be linked to increased risk of depressive conditions or depression. The aim of this study was to review all available evidence on vitamin D, depression, and any association between them. Cross-sectional, case-control, and cohort studies have reported contradictory results. Some have reported that low levels of vitamin D may be associated with higher risk of depression or depressive symptoms while others reported that vitamin D status may not be related to depression. Recent clinical trials examining the effects of vitamin D supplementation on depression have also showed discrepant results. However, meta-analysis study results are consistent regarding the beneficial effects of vitamin D. Several mechanisms that account for these beneficial effects of vitamin D on depression have been reported but remain largely speculative. Vitamin D deficiency is very common, and prevalence of depression is increasing in the Asian population, especially females. However, limited literature is available on this population. Considering research results of a potential inverse association between vitamin D level and prevalence of depression, it is important to advance our understanding of the role of vitamin D in depression and conduct well-designed prospective trials in the Asian population.

Dioxins and Health: Human Exposure Level and Epidemiologic Evidences of Health Effects (다이옥신과 건강: 인체 노출 수준 및 건강영향에 대한 역학적 연구)

  • Jang, Jae-Yeon;Kwon, Ho-Jang
    • Journal of Preventive Medicine and Public Health
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    • v.36 no.4
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    • pp.303-313
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    • 2003
  • General information is summarized, that is necessary to introduce a scientific assessment of the human health and exposure issue concerning dioxin and dioxin-like compound. Scientific literatures were reviewed to assess the background exposures to the dioxin-like compounds for normal residents. Epidemiologic studies were also reviewed to assess malignant and nonmalignant sweets of dioxins. In 1997, the International Agency for Research on Cancer classified 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) as a human carcinogen, primarily based on occupational cohort studies. The US Environmental Protection Agency made the same decision in it's Draft Dioxin Reassessment. Epidemiologic evidences point to a generalized excess of all cancers, without any pronounced excess at specific sites. Reported non-cancer effects included a range of conditions affecting most systems. Among them, chloracne, elevation in gamma glutamyl transferase(GGT), and alterations in reproductive hormones are related to TCDO, Other adverse outcomes, such as lipid concentrations, diabetes, circulatory and heart diseases, immunologic disorders, neurobehavioral effects, and developmental outcomes require further study before their respective relationships to TCDD can be more definitively assessed.