• Title/Summary/Keyword: 측정효율

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Development of a Method for Analyzing the Nicotine Content in Synthetic Flavoring Substances as Unauthorized E-cigarette Liquid by Using HPLC (전자담배 액상 충진제와 유사한 합성착향료 중 니코틴의 HPLC 분석법 개발)

  • Kim, Jae-Young;Lee, Sang-Mok;Chang, Moon-Ik;Cho, Yoon-Jae;Lee, Han-Jin;Chae, Young-Sik;Rhee, Gyu-Sik
    • Korean Journal of Food Science and Technology
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    • v.45 no.6
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    • pp.693-699
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    • 2013
  • A simple, sensitive, and specific method for quantifying the nicotine content of synthetic favoring substances (SFS) was developed using high performance liquid chromatography (HPLC) with a photo-diode array detector (PDA). Nicotine was extracted from SFS samples by using an acid-base liquid-liquid extraction method with dichloromethane and distilled water. The nicotine content was quantified by HPLC/PDA (261.9 nm) with a $C_{18}$ column under a gradient of 10% acetonitrile with 20 mM ammonium formate (ammonia solution adjusted to pH 8.7) to 100% acetonitrile. The calibration curve, analyzed from concentration standards between 0.1 to 2 mg/L, presented linearity with a correlation coefficient ($r^2$)>0.9999. The limit of quantitation (LOQ) of nicotine in SFS was 0.4 mg/kg, and the average recoveries ranged from 76.4% to 96.3%. The repeatability of measurements, expressed as the coefficient of variation (CV%), ranged from 1.74 to 5.12%. This newly developed method for nicotine quantification in SFS can be considered an analytical method with an acceptable level of sensitivity and repeatability.

Antioxidant activity of premature mandarin vinegar according to harvest period and raw material conditions (수확시기 및 원료 조건에 따른 풋귤 식초의 항산화 활성)

  • Park, Boyeon;Choi, Jae Won;Kim, Sung Hyun;Yun, Ye-Rang;Lee, Young ran;Lee, Young mi;Jung, Ji-Hye
    • Korean Journal of Food Science and Technology
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    • v.52 no.4
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    • pp.333-341
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    • 2020
  • This study aimed at comparing the antioxidant activity of premature mandarin (PM) vinegars by varying harvest periods (July, August, and September) and raw material conditions (PM fruit, PMF; PM fruit with 10% dried Citri Unshius Pericarpium Immaturus (CUPI), PMF-D, and PM fruit with 10% roasted CUPI, PMF-R). We found that the PM harvested in July exhibited the highest phenol content. Meanwhile, the July and August harvests showed stronger DPPH radical scavenging and reducing power. The phenol content of PMF-R vinegar was 0.62±0.02 ㎍ GAE/mL, more than two times higher than that of PMF vinegar. The DPPH radical scavenging capacity and reducing power were the highest in the PMF-R vinegar, at 4.71±0.07 and 7.47±0.28 nL/mL, respectively. Therefore, it could be expected that PM vinegar prepared by adding roasted CUPI and harvested in July would exhibit high antioxidant activity and could be used as functional vinegar.

The Analysis of Activities and Satisfaction of Volunteers for Hospice Care (호스피스 자원봉사자의 활동 및 만족도 분석)

  • Kim, Boon-Han;Jung, Yun;Park, Kyung-Bok
    • Journal of Hospice and Palliative Care
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    • v.5 no.2
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    • pp.163-171
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    • 2002
  • Purpose : The purpose of this study was to analyze activities and satisfaction of volunteers for hospice care. Methods : We used 271 reports of hospice care and 20 questionnaire of activities and satisfaction of volunteers for hospice care from volunteers of in a community. Window SPSS-PC was used for the data analysis and the statistical method used were the descriptive statistics, t-test, ANOVA and Pearson's correlation coefficient. Results : 1) The highest score of activity was emotional area and the next activities was physical area. 2) The degree of emotional area (t=4.94, P<.05) and spiritual area (t=3.80, P<.05) was influence by religion of volunteers. 3) The mean score of satisfaction was 3.61. 4) There was correlation between duration of activity and death experience (r=.558, P<.05), emotional care (r=.698, P<.01), spiritual care (r=.474, P<.05), satisfaction (r=.651, P<.01), and the between physical care and family care (r=.559, P<.05), and the between spiritual cue and family care (r=.512, P<.05), and between emotional care and satisfaction (r=.536, P<.05). Conclution : The above result indicated that we must develope the management and education of volunteer of hospice care for various hospice care. Also, We should to encouraged the continuous education and efficient management.

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Evaluation of a Community-Based Cancer Patient Management Program: Collaboration between a Hospice Center and Public Health Centers (병원 호스피스센터-보건소 연계를 통한 지역사회 재가암환자 관리 프로그램 평가)

  • Lee, Hae-Sook;Park, Sun-Hee;Chung, Young-Soon;Lee, Boo-Kyung;Kwon, So-Hi
    • Journal of Hospice and Palliative Care
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    • v.13 no.4
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    • pp.216-224
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    • 2010
  • Purpose: The purpose of this study was to evaluate a community-based cancer patient management program (CBPCMP) which was collaborated between a hospice center and public health centers. Methods: The CBPCMP proceeded on four steps; 1) Signing agreements with three public health centers, 2) Enrolling the domiciliary terminal cancer patients, 3) Providing home hospice service, and 4) Inquiring patient's level of satisfaction. From February 1 to December 31 in 2009, 43 terminal cancer patients were referred and provided with home hospice service. The hospice team made a total of 605 visits. Medical records for each visit and data from satisfaction surveys were analyzed. Results: 76.7% of patients were older than 60 years, and 90.7% of the patients were alert. The level of functional status for 76.7% of patients rated as lower than ECOG grade 1. 62.8% of the patients or their caregivers signed hospice service agreements. On the initial evaluation, the most frequent reasons for referral were general weakness (86.0%), followed by anorexia (72.1%). Nurses visited the patients' most frequently (371 visits), followed by volunteers (216 visits). Nurses provided emotional support and health promotion counseling on 95.1% and 22.9% of visits, respectively. The mean satisfaction score rated by patients and their family was 4.45 out of 5. Conclusion: This study tested CBPCMP in collaboration with hospice centers and public health centers. CBPCMP showed a possibility to improve the quality of end of life care. To insure the quality care, however, the guidelines for home hospice service should be developed.

Effects of the Planetarium Lesson on Students' Understanding of Astronomical Concepts (천체투영관 수업이 학생들의 천문 개념 이해에 미치는 효과)

  • Kim, Wansoo;Shim, Hyunjin
    • Journal of Science Education
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    • v.42 no.1
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    • pp.49-65
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    • 2018
  • Astronomy is the subject that can easily draw students' interest in studying science, therefore plays an important role in developing scientific core competence. However, it is difficult to develop spatial thinking that is required in understanding astronomical concepts through the classroom lessons. Planetarium, along with the science museum, is one of the most representative informal educational institution where astronomical concepts can be taught beyond time and space constraints. In this study, we developed the astronomy education program that is operated in the planetarium and applied the program to the elementary, middle and high-school students to investigate the effects of the planetarium lesson compared to the classroom lesson. The duration of this research was about 8 months, and the number of the students involved is 761, including participants of the 1 night and 2 days camps in the Daegu National Science Museum. The newly developed planetarium lesson is comparable to the previous classroom lesson of which topics are cardinal points, constellation, and the rotation of the earth. Test items were developed to evaluate the understanding of the astronomical concepts. The study was conducted based on the pre- and post-test with non-equivalent groups design comparing classroom and planetarium lessons. The results of this study are as follows. First, planetarium lesson is more effective for understanding astronomical concepts such as the cardinal points, earth's rotation, and the constellation than classroom lesson. Second, planetarium has a positive effect irrespective of gender and previous knowledge. Third, planetarium for high school students has the same effect as additional observation activities followed by the classroom instruction. Therefore, planetarium can be used as an alternative, effective tool when night observation is not available. In summary, planetarium is an effective tool that helps students to understand the astronomical concepts.

Studies on the Estimation of the Genetic Parameters on All Traits in Korean Native Ogol Fowl IV. Estimations of the Heritabilities and Genetic Correlations on the Body Conformations (한국재래오골계의 제형질에 대한 유전모수 추정에 관한 연구 IV. 체형에 대한 유전력 및 유전상알 추정)

  • 한성욱;상병찬;김홍기
    • Korean Journal of Poultry Science
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    • v.18 no.1
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    • pp.1-8
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    • 1991
  • This study was conducted to estimate heritabilities and genetic correlations on body shape components in Korean Native Ogol fowl , The data analysis were record of 450 pullets producted from 150 dams and 20 sires of Korean Native Ogol fowl raised at Chungnam National University from June 18, 1987 to April 6, 1989. The results obtained are sammarized as follows ; 1. On the body components, shank length at 8, 24 weeks and 300 days of age were $8.717\pm$0.363, $9.576\pm$0.390 and $9.646\pm$0.389cm, the breast width were 3.469$\pm$0.234, $4.310\pm$0.345 and $4.752\pm$0.343cm; the breast girth at 8, 24weeks and 300 days of age were $22.819\pm$1.082, $36.719\pm$1.793 and $39.008\pm$1.709cm; the tibia length at 8, 24weeks and 300days of age were $9.941\pm$0.888, $13.183\pm$0.499 and $13.560\pm$0.552cm. 2. The heritability estimates of body shape components based on the variances of sires, dams and combined components from 8, 24 weeks and 300 days of age were 0.235-0.290, 0.589-0.890 and 0.437-0.565 for shank length ; 0.185-0.237, 0.444-0.536 and 0.314-0.392 for breast width ; 0.218-0.552, 0.499-0.746, 0.486-0.558 for breast girth ; 0.339-0.432, 0.281-0.543 and 0.340-0.446 for tibia length, respectively. 3. The genetic correlation coefficient of body shape components were as follows ; between shank length and breast width, breast girth, tibia length were 0.237-0.836, 0.277-0,729 and 0.378-0.915;between breast width and breast girth, tibia length were 0.637-0.889 and 0.384-0.903;between breast girth and tibia length was 0.905-0.995, respectively.

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Comparison of Electrical Signal Properties about Top Electrode Size on Photoconductor Film (광도전체 필름 상부 전극크기에 따른 전기적 신호 특성 비교)

  • Kang, Sang-Sik;Jung, Bong-Jae;Noh, Si-Cheul;Cho, Chang-Hoon;Yoon, Ju-Sun;Jeon, Sung-Pyo;Park, Ji-Koon
    • Journal of the Korean Society of Radiology
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    • v.5 no.2
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    • pp.93-96
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    • 2011
  • Currently, the development of direct conversion radiation detector using photoconductor materials is progressing in widely. Among of theses photoconductor materials, mercuric iodide compound than amorphous selenium has excellent absorption and sensitivity of high energy radiation. Also, the detection efficiency of signal generated in photoconductor film varies by electric filed and geometric distribution according to top-bottom electrode size. Therefore, in this work, the x-ray detection characteristics are investigated about the size of top electrode in $HgI_2$ photoconductor film. For sample fabrication, to solve the problem that is difficult to make a large area film, we used the spatial paste screen-print method. And the sample thickness is $150{\mu}m$ and an film area size is $3cm{\times}3cm$ on ITO-coated glass substrate. ITO(Indium-Tin-Oxide) electrode was used as top electrode using a magnetron sputtering system and each area is $3cm{\times}3cm$, $2cm{\times}2cm$ and $1cm{\times}1cm$. From experimental measurement, the dark current, sensitivity and SNR of the $HgI_2$ film are obtained from I-V test. From the experimental results, it shows that the sensitivity increases in accordance with the area of the electrode but the SNR is decreased because of the high dark current. Therefore, the optimized size of electrode is importance for the development of photoconductor based x-ray imaging detector.

The Improvement of Knowledge and Management Capability of Oral Health according to the Oral Health Education System for Elementary School Students (구강보건교육에 의한 초등학교 학생의 구강보건 지식도와 구강위생관리능력의 변화)

  • Jeon, Hyun-Ja;Song, Keun-Bae;Lee, Sung-Kook
    • Journal of the Korean Society of School Health
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    • v.12 no.2
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    • pp.295-303
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    • 1999
  • The purpose of this study was to evaluate the effect of systemic oral health education on the improvement of knowledge levels and patient hygiene performance(PHP) for elementary school students. The randomly selected 1st and 5th grade students in a public elementary school of Taegu city were divided by education group(118 students) and non-education group(122 students). The oral health education lesson was systematically held on the education group once a month for 4 months. The questionnaire queried all the subjects about their knowledge and attitudes before and after oral health education, and PHP was also tested at the same time. Corresponding p-values were significantly considered at values less than 0.05. The obtained results were as follows: Due to the oral health education lesson, the education group of both 1st and 5th grade students came to have a higher knowledge level than the non-education group. There was high improvement of items such as toothbrushing time, toothbrushing method, cause of dental caries, treatment after tooth damage, and tongue-brushing. Therefore, these items should be educated to all the elementary school students. By increaseing the knowledge level of oral health after education, the PHP index in the education group was significantly decreased in comparison to the non-education group and hence the capability of oral health management improved. From the above results, a systematically and periodically oral health education system for elementary school students can improve the knowledge level and capability of oral health management. Further study will be required to develop an easy and acceptable systemic oral health education program for elementary schools.

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Gadoteridol's Signal Change according to TR, TE Parameters in T1 Image (T1영상에서 TR, TE 매개변수에 따른 Gadoteridol의 신호강도 변화)

  • Jeong, Hyun Keun;Jeong, Hyun Do;Nam, Ki Chang;Kim, Ho Chul
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.9
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    • pp.117-124
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    • 2015
  • In this paper, we introduce how to control TR, TE physical MR parameters for managing $H_1$ spin's SI(Signal Intensity) which is combined with gadolinium following administration MR agent in T1 effect for diagnostic usefulness. we used MRI phantom made with 0.5 mol Gadoteridol. This phantom was scanned by FSE sequence with different TR, TE parameters. In this study, to make T1 effect, TR was 200, 250, 300, 350, 400, 450, 500, 550, 600 msec. In addition to, TE was 6.2, 12.4, 18.6, 21.6 msec. The results were as follows ; Each RSP(Reaction Starting Point) was 100, 50, 40, 30 mmol in TE 6.2, 12.4, 18.6, 21.6 msec being irrelevant to TR. In MPSI(Max Peak Signal Intensity), 4 mmol was showed in TR 200 msec while peak signal was decreased to low concentration mol in TR 250-600 msec. In terms of RA(Reaction Area), the highest SI was TE 6.2 msec in TR 200-600msec. According to the study, we are able to recognize it is possible to control enhance rates by managing TR and TE of MR parameters; moreover, we expect that enhanced T1 image in MR clinical field can be performed in a practical way with this quantitative data.

Effects of Scutellaria baicalensis Water Extract on Lipid Metabolism and Antioxidant Defense System in Rats Fed High Fat Diet (황금추출물이 고지방 식이를 급여한 흰쥐의 지질대사 및 항산화방어계에 미치는 영향)

  • Yoon, Hye-Jin;Park, Young-Sook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.2
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    • pp.219-226
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    • 2010
  • The objective of this study was to determine the effects of a Scutellaria baicalensis water extract (SDWE) on lipid levels, lipid peroxidation and antioxidant enzyme activities on rats fed a high fat diet for 6 weeks. Thirty-two male Sprague-Dawley rats (4-weeks-old) were randomly divided into four groups: normal diet and deionized water (ND), normal diet and Scutellaria baicalensis water extract (NDS), high fat diet and deionized water (HFD), high fat diet and Scutellaria baicalensis water extract (HFDS). The food intakes were significantly lower, but the food efficiency ratios were significantly higher in the high fat diet groups than those in other groups. The level of HDL-cholesterol and HDL-cholesterol/total cholesterol ratio in plasma were significantly higher and AI (atherogenic index) in HFDS group was significantly lower than that in HFD group. The level of triglyceride in plasma was significantly decreased in SDWE groups. The triglyceride of liver was significantly increased in the high fat diet groups and the total cholesterol of liver in the HFDS group was significantly lower than that in the HFD group. The plasma and liver concentrations of thiobarbituric acid reactive substances (TBARS) in the NDS group were significantly lower than those in the ND group. The total antioxidant status (TAS) in plasma was significantly increased in the HFDS group compared to the HFD group. The activities of SOD, catalase and GST were significantly increased in SDWE groups compared to ionized water groups. The activity of GSH-Px and the concentration of GSH in liver in the HFDS group were significantly higher than those in the HFD group. These results suggest that a supplement of SDWE on rats fed high fat diet reduce levels of lipid and lipid peroxidation in plasma and liver and improve the antioxidant defense systems.