• The Journal of the Convergence on Culture Technology
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• v.5 no.4
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• pp.105-114
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• 2019

Daytime activity services based on community care signify 'participatory integrated community care service' fused with diverse forms of community participation and care for adults with developmental disabilities after school graduation. They have the characteristics of lifelong care by life cycle in that adults with developmental disabilities 18 years and older receive daytime care and community participation programs. The purpose of this study is to examine community care based daytime activity services and to search for vitalization plans for daytime activity services that must unfold in the future for care programs that can be meaningful social participation opportunities for adults with developmental disabilities. Through literature review, we analyzed the state of daytime and social activity of adults with developmental disabilities as community care.Based on these findings, we devised ways to improve the daytime activities for the significant daytime of adults with developmental disabilities. At this, it proposed an increase of activity support vouchers, daytime activity service time expansions, expanded budget formulation for an increased number of daytime activity service subjects, expanded applications for the prioritization of the 20% of those with the most severe developmental disabilities and the composition of separate teams, and the role reinforcement of support centers for people with developmental disabilities.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.4
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• pp.45-56
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• 2012

Objective : This study was done to investigate the correlation between general quality of life(QOL) and disease specific QOL of tinnitus patients. Methods : 2009 National health and nutrition survey(NHNS) data were employed for analyzing the mean estimates of total population and tinnitus sub-group patients, and predicting the regression equation of mapping between EQ-5D and disease severity. Baseline statistical analyses and normality tests were done by using Student t-test, Chi-square test, Shapiro-Wilk test and ladder test. Hierarchial regression analyses were performed using related variables and predicted the optimal regression equations. Statistical significance was achieved if the probability was less than 5%. Results : Firstly, the standardized prevalence of tinnitus patient in South Korea was 18.69% and over 90th age-group was relatively higher than other groups. Mean value of domestic QOL measured by EQ-5D was estimated as 0.9486 and QOL of tinnitus subgroup(0.9169) was lower than the non-tinnitus subgroup(0.9559), significantly. Stratified by age and sex, QOLs of all sub-groups with tinnitus were lower than without tinnitus sub-groups significantly. Regression equations from 2009 NHNS data were developed using hierarchial regression analysis which is as follows. $$Y_{EQ-5D}=0.9224-0.0079{\times}T1-0.0261{\times}T2-0.0951{\times}T3+\sum_{i=1}^{n}{\beta}_i{\times}X_i\\{\hspace{95}}(0.0106){\hspace{3}}(0.0037){\hspace{30}}(0.0072){\hspace{30}}(0.0038)$$ ($X_i$=Other explanatory variables except Tinnitus QOL1, 2, 3, ${\beta}$= Regression Coefficient of Model 4) Conclusion : We confirmed the correlation among THI and EQ-5D and HUI-III, and developed the inference for regression equation of EQ-5D.

• Korean journal of applied entomology
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• v.60 no.3
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• pp.323-329
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• 2021

This study investigated the seasonal distribution of ticks in Boeun, Chungbuk, South Korea, from 2016 to 2020. Over the five-year period, ticks were collected annually from four different sites. A total of 17,704 ticks belonging to three tick species (Haemaphysalis longicornis, Haemaphysalis flava, and Ixodes nipponensis) were collected. H. longicornis was the dominant species across all four sites with the highest density of 68.40% of the total collected specimens, followed by H. flava (3.53%) and I. nipponensis (0.06%). The larvae of unidentified species were also collected: 11.81 T.I. (28.01%). The H. longicornis population peaked during the spring season (May-June), whereas the larval population peaked during August and September. H. longicornis was collected the most from four sites (coniferous forest, broad-leaf forest, mountain path, and copse), with the exception of the larvae, which was collected the most in grassland and grave. H. flava was collected from all sites, but in a small proportion. The SFTS virus was not found in any of the 828 pools of ticks during 2016-2020. Based on the results of this study, the continuous surveillance of the tick population is recommended to mitigate the spread of diseases by these vectors.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.4
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• pp.342-352
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• 2021

We used data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES) (2016~2018) to investigate an association between high sensitivity C-reactive protein (hsCRP) and uric acid in the obese. Obesity was defined as a body mass index (BMI) of 25 kg/m² or more, severe obesity as a BMI of 30 kg/m² or more, and morbid obesity as a BMI of 35 kg/m² or more. In the complex samples multiple logistic regression, despite adjustment by adding major risk factors, the odds ratio (OR) for obesity was higher in the group with high levels of both, hsCRP and uric acid than the reference group at all stages (obesity, OR 1.89, P<0.001 vs. severe obesity, OR 5.04, P<0.001 vs. morbid obesity, OR 8.20, P<0.001). The association between hsCRP and uric acid in obese patients increased from 1.89 to 8.20 as the obesity level increased, suggesting that participants with increased BMI were significantly affected by hsCRP and uric acid. Moreover, the interaction between hsCRP and uric acid was statistically significant even in the model corrected for major confounding factors (P for interaction=0.009).

• Journal of Korean Foot and Ankle Society
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• v.24 no.4
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• pp.129-134
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• 2020

Purpose: This study compared the results of proximal and distal chevron osteotomy in patients with severe hallux valgus. Several recent studies have shown that the indications for distal metatarsal osteotomy with a distal soft-tissue procedure could be extended to include severe hallux valgus. Materials and Methods: This study analyzed 127 severe hallux valgus surgeries. Of these, 76 patients (76 feet) were excluded for lack of adequate follow-up and additional procedures (Akin procedure), leaving 51 patients (51 feet) in the study. The mean age of the patients was 58 years (21~83 years), and the mean follow-up duration was 18 months (12~32 months). The patients were divided into two groups. Group 1 underwent distal chevron osteotomy, and group 2 underwent proximal chevron osteotomy performed sequentially by a single surgeon. The patients were interviewed for the American Orthopaedic Foot and Ankle Society (AOFAS) score before and one year after surgery. The anteroposterior weight-bearing radiography of the foot was taken before and one year after surgery. Results: There were no significant differences in pain and function after one year in either group. Both groups experienced significant pain reduction and an increase in the AOFAS score. Significant improvement of the hallux valgus and intermetatarsal angle corrections was observed in both groups, and the sesamoid position was similar in each group. More improvement in radiographic correction of intermetatarsal angle was noted in group 2. Both procedures gave similar good clinical and radiological outcomes. Conclusion: This study suggests that a distal chevron osteotomy with a distal soft-tissue procedure is as effective and reliable a means of correcting severe hallux valgus as a proximal chevron osteotomy with a distal soft-tissue procedure.

• Journal of Digital Convergence
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• v.19 no.9
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• pp.229-239
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• 2021

This study is to identify the factors influencing the attitudes, behavior controls, and subjective norms related to COVID-19 vaccination on the intention of preventive behavior in K provincial residents. A total of 232 people agreed to participate in the study. Data were analyzed using descriptive statistics, t-test, ANOVA, correlation, and Hierarchical analysis. As a result of this study, the factors that had a statistically significant effect on the intention to conduct COVID-19 vaccination were perceived behavioral control (β=.39, p<.001) and attitude toward COVID-19 preventive behavior (β=.24, p<.001), followed by subjective norm (β=.24, p<.001). The explanatory power for this was 56.8%. The COVID-19 vaccine is an important means of ending the COVID-19 pandemic and helps prevent infection or worsening of COVID-19 and protect those around you. In the post-COVID-19 situation, it is necessary to improve the intention of vaccination against COVID-19 and to take active measures and strategies. At this point in time when COVID-19 vaccination is becoming more prevalent across the country, we hope that the intent of the COVID-19 vaccination action will translate into a COVID-19 vaccination action.

• Journal of Food Hygiene and Safety
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• v.36 no.5
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• pp.363-375
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• 2021

Trends in the developing era to discover and design peptide-based treatments throughout an epidemic infection scenario such as COVID-19 could progress into a more efficient and low-cost therapeutic environment. However, the weakening of proteolysis is one downside of natural peptide drugs. But, peptidomimetics may help resolve this issue. In this review, peptide and peptide-based drug discovery were summarized to target one key entry mechanism of severe coronavirus pulmonary emboli syndrome (SARS-CoV-2), which encompasses the association of the host angiotensin-converting enzyme-2 (ACE2) receptor and viral spike (S) protein. Furthermore, the benefits of proteins, peptides and other possible actions that have been studied for COVID-19 through new peptide-based treatments are discussed in the review. Lastly, an overview of the peptide-based drug therapy environment is comprised of an evolutionary viewpoint, structural properties, operational thresholds, and an explanation of the therapeutic area.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.3
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• pp.266-276
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• 2021

Fundus hemorrhage refers to abnormalities in the retinal tissue and blood vessels. Therefore, when a hemorrhagic change in the fundus occurs, the ophthalmologist orders various ophthalmic tests to evaluate the degree of hemorrhage and determine the progress of the lesion before, during, and after treatment to accordingly establish a treatment plan. Currently, the most useful and universal fundus examination includes optical coherence tomography (OCT), fundus photography (FP), and fluorescein angiography (FAG). Existing fluorescein angiography test methods for establishing a treatment plan for severe fundus bleeding have limitations. The authors propose that peripheral pupil and the 5-quadrant method should be performed using ultra-wide-angle fluorescence fundus angiography (UWFFA). Using this method, it is possible to quickly determine the area to be described, avoid the radius of bleeding as much as possible, and provide the ophthalmologist with a range of damaged tissue and abnormal blood vessels. Nevertheless, there are cases in which ophthalmologists judge that fundus bleeding is so severe that ultra-wide-angle fluorescence fundus angiography is meaningless. In such cases, ophthalmic ultrasound and electroretinogram may be used in that order as alternative methods of examination. Therefore, some clinical situations require the use of ophthalmic ultrasound and electroretinogram and should be performed accurately.

• Journal of the Korean Society of Radiology
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• v.15 no.6
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• pp.911-917
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• 2021

Severe Acute Respiratory Syndrome is being impacted worldwide by the prolonged COVID-19 situation. Due to the impact of COVID-19, domestic educational institutions have also changed their teaching methods. Domestic universities traditionally aim for face-to-face lectures, but due to the pandemic, they are conducting non-face-to-face lectures. This study aims to evaluate the effect of non-face-to-face lectures on radiology students. The subjects of this study are students of the Department of Radiology at University D in Daegu. As for the contents of the study, satisfaction with non-face-to-face lecture delivery, concentration, and comprehension was evaluated. Data analysis was performed in SPSS Ver. 26 was used, and the reliability measurement was found to be Cronbach's alpha coefficient = 0.805. In the results of this study, the satisfaction of non-face-to-face lecture delivery, concentration, and comprehension was overall high. However, satisfaction with theoretical subjects (2.08±0.88) was significantly different from that of practical subjects (2.51±1.10) (t=-9.880, p<.001). Satisfaction by grade level was highest in the first grade. As a result, it is judged that non-face-to-face theoretical lectures require more careful preparation from lecture planning than practical lectures, and further research is expected in the future.

• Journal of The Korean Society of Clinical Toxicology
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• v.19 no.2
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• pp.72-82
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• 2021

Purpose: A high anion gap (AG) is known to be a significant risk factor for serious acid-base imbalances and death in acute poisoning cases. The strong ion difference (SID), or strong ion gap (SIG), has recently been used to predict in-hospital mortality or acute kidney injury (AKI) in patients with systemic inflammatory response syndrome. This study presents a comprehensive acid-base analysis in order to identify the predictive value of the SIG for disease severity in severe poisoning. Methods: A cross-sectional observational study was conducted on acute poisoning patients treated in the emergency intensive care unit (ICU) between December 2015 and November 2020. Initial serum electrolytes, base deficit (BD), AG, SIG, and laboratory parameters were concurrently measured upon hospital arrival and were subsequently used along with Stewart's approach to acid-base analysis to predict AKI development and in-hospital death. The area under the receiver operating characteristic curve (AUC) and logistic regression analysis were used as statistical tests. Results: Overall, 343 patients who were treated in the intensive care unit were enrolled. The initial levels of lactate, AG, and BD were significantly higher in the AKI group (n=62). Both effective SID [SIDe] (20.3 vs. 26.4 mEq/L, p<0.001) and SIG (20.2 vs. 16.5 mEq/L, p<0.001) were significantly higher in the AKI group; however, the AUC of serum SIDe was 0.842 (95% confidence interval [CI]=0.799-0.879). Serum SIDe had a higher predictive capacity for AKI than initial creatinine (AUC=0.796, 95% CI=0.749-0.837), BD (AUC=0.761, 95% CI=0.712-0.805), and AG (AUC=0.660, 95% CI=0.607-0.711). Multivariate logistic regression analyses revealed that diabetes, lactic acidosis, high SIG, and low SIDe were significant risk factors for in-hospital mortality. Conclusion: Initial SIDe and SIG were identified as useful predictors of AKI and in-hospital mortality in intoxicated patients who were critically ill. Further research is necessary to evaluate the physiological nature of the toxicant or unmeasured anions in such patients.