• Title/Summary/Keyword: 조직 유효성

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Measurements of Actual Effective Half-Life in $^{131}I$ Therapy for Graves' Hyperthyroidism (그레이브스 갑상선기능항진증 환자의 방사성옥소($^{131}I$) 치료시 실제 유효반감기의 측정)

  • So, Yong-Seon;Kim, Myung-Seon;Kwon, Ki-Hyun;Kim, Seok-Whan;Kim, Tae-Hyung;Han, Sang-Woong;Kim, Eun-Sil;Kim, Chong-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.30 no.1
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    • pp.77-85
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    • 1996
  • Radioiodine($^{131}I$) has been used for the treatment of Graves' hyperthyroidism since the late 1940's and is now generally regarded as the treatment of choice for Graves' hyperthyroidism who does not remit following a course of antithyroid drugs. But for the dose given, several different protocols have been described by different centers, each attempting to reduce the incidence of long-term hypothyroidism while maintaining an acceptable rate control of Graves' hyperthyroidism. Our goals were to evaluate effective half-life and predict absorbed dose in Graves' hyperthyroidism patients, therefore, to calculate and readminister radioiodine activity needed to achieve aimed radiation dose. Our data showed that the mean effective $^{131}I$ half-life for Graves' disease is 5.3 days(S.D=0.88) and mean biologic half-life is 21 days, range 9.5-67.2 days. The mean admininistered activity and the mean values of absorbed doses were 532 MBq(S.D.=254), 112 Gy (S.D.=50.9), respectively. The mean activity needed to achieve aimed radiation dose were 51MBq and marked differences of $^{131}I$ thyroidal uptake between tracer and therapy ocurred in our study. We are sure that the dose calculation method that uses 5 days thyroidal $^{131}I$ uptake measurements after tracer and therapy dose, provides sufficient data about the effective half-life and absorbed dose of $^{131}I$ in the thyroid and predict the effectiveness of $^{131}I$ treatment in Graves' hyperthyroidism.

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새로운 식품소재로서의 의곡류 amarans, quinoa의 제빵 특성에 관하여

  • Morita, Naofumi
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2000.04a
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    • pp.6-7
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    • 2000
  • 개발도상국의 급격한 인구 증가에 의해 세계 60억 이라는 인구도 2050년을 맞아 약 100억에 도달할 것이라고 일컬어진다. 이로 인한 장래의 식량 위기에 대비하여 벼, 밀, 옥수수 등의 증산, 품종 개발도 물론 필요하지만 선진국을 중심으로 시장성 높은 작물의 소비가 우선되어지는 상황에 맞추어 세계적으로 주식이 될 수 있는 새로운 곡류의 확보와 생산체제도 중요한 문제이다. 한편으로 생활의 향상에 따른 식물의 다양화와 건강지향의 관점으로 본 다 품목 소량형의 식생활을 하는 것이 식물성 allergy의 방지 측면으로서의 곡류 특히 잡곡류의 유효 이용이 부각되어진다. 이들 중 amarans, quinoa는 벼과 식물에 비교해서 광합성능이 좋은 C4식물로서 생장이 빠르고 동시에 비타민, 무기질, 지질이 풍부하고 구성 단백질 중에 필수 아미노산을 많이 함유하여 아미노산 등급도 높고 특히 영양 발란스도 우수하다. 또 cholesterol 저하작용, 식물섬유에 의한 대장암의 억제 작용 등이 잘 알려져 있다. 그리l고 quinoa에 대해서는 아메리카 항공우주국(NASA)에서 CELSS(Controlled Ecological Life Support System; 장기간 우주특무비행의 승선원을 위한 공기중의 이산화탄소를 제거하고 식량·산소·물을 만들어 내기 위해 식물을 이용하는 방법)에 적합한 작물 후보로써 선택되어 신규 식품소재로써 주목받고 있다. 이상과 같은 견지로부터 amarans, quinoa를 일상식화되고 있는 빵에 이용하기 위해 제빵성 및 혼합중의 반죽의 모든 성질에 대해서 검토했다. amarans는 초과의 Amaranthus에 속하고 주요 생산국은 아메리카, 멕시코, 페루등이지만 일본에서는 주로 A.hypochondriacus가 수입되어 이용 되어지고 있다.amarans의 가루는 단독으로는 점탄성 있는 반죽을 형성하지 않기 때문에 밀가루에 일부를 대용한 wheat flour dough를 사용하고 가정용 제빵기로 구워 최종 단계에까지의 제빵성 결과를 산출했다. amarans folur 5%의 대체에는 빵의 비용적이 비교적 증대했지만 그 이상 amarans flour을 대처하면 확연히 비용적은 감소했다. amarans flour 10% 대체에 hemicellulase 1250U 이상을 첨가하면 비용적은 눈에 띄게 증대했다. farinograph에 있어서 반죽의 안정성은 amarans flour 10% 대용에 현저히 감소했다. 반죽의 점탄성(아축응력, 탄성률, 점성계수)는 amarans flour 10%를 대용한 것이 무첨가한 것보다 많이 단단해졌음을 알 수 있었다. 혼합중의 반죽의 조사형 전자현미경 관찰로 amarans flour로 대체한 gluten이 단단해졌음을 알수 있었다. 유화제 stearly 칼슘, 혹은 hemicellulase를 amarans 10% 대체한 밀가루에 첨가하면 확연히 비용적을 증대시킬 수 있다는 사실을 알 수 있었다. quinoa는 명아주과 Chenopodium에 속하고 페루, 볼리비아 등의 고산지에서 재배 되어지는 것을 시료로 사용하였다. quinoa 분말은 중량의 5-20%을 quinoa를 대체하고 더욱이 분말중량에 대하여 0-200ppm의 lipase를 lipid(밀가루의 2-3배)에 대하여 품질개량제로서 이용했다. 그 결과 quinoa 대량 7.5%에서 비용적, gas cell이 가장 긍정적 결과를 산출했고 반죽의 조직구조가 강화되었다. 또 quinoa 대체에 의해 전분-지질 복합제의 흡열량이 증대된 것으로부터 전분-지질복합제의 형성 촉진이 시사되었다.이것으로 인하여 호화억제에 의한 노화 방지효과가 기대되었지만 실제로 빵의 노화는 현저히 진행되었다. 이것은 quinua 대체량 증가에 따른 반죽의 안정성이 저하되어 버린 것으로 생각되어진다. 더욱이 lipase를 첨가하면 반죽이 분화하는 경향이 보여졌지만 첨가량 75ppm에 있어서 상당히 비용적의 증대가 보였다. 이것은 lipase의 가수분해에 의해 생긴 monogliceride에 의한 유화각 일어나서 보존성이 개선되어진 것으로 quinoa를 보다 많이 빨에 이용하기 위해서는 lipaserk 품질개량제로서 유효하다는 것을 알 수 있었다. 또 lipase는 quinoa의 대체량이 비교적 많은 10-20%의 섭취가 곧 allergy 질환 문제의 개선책이 되는 것은 물론 amarans, quinoa에는 lysine, 함황아미노산이 많고 지질중의 지방산조성도 좋고 무기질도 많이 함유되어 있다. 이와같이 우리들 개인의 건강에 대한 배려도 있고 amarans, quinoa등의 식품재료를 적극적으로 사용할 수 있도록 유념해 두었으면 하는 바램이다.

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Tissue Mimicking Phantom for Visualization of Temperature Elevation Caused by Ultrasound (초음파에 의한 온도상승 가시화용 생체 모의매질)

  • Jung, Ji-Hee;Kim, Jung-Soon;Ha, Kang-Lyeol;Kim, Moo-Joon;Cao, Yonggang
    • The Journal of the Acoustical Society of Korea
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    • v.33 no.5
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    • pp.291-299
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    • 2014
  • To probe the temperature elevation effect caused by ultrasound, a tissue mimicking phantom was newly suggested. A carrageenan gel was adopted to realize not only the required transparency for visualization but also acoustic characteristics similar to human tissue. To visualize the temperature elevation inside phantom, thermochromic film with a critical temperature of discoloration was introduced. Acoustic characteristics of the tissue mimicking phantom were examined when the concentrations of carrageenan and sucrose changed. As the results, the attenuation coefficient of the phantom could be controlled in the range of 0.44~0.49 dB/cm/MHz, and the acoustic impedance in the range of 1.52~1.77 Mrayls. We could control the acoustic characteristics of the phantom by different concentration of carrageenan and sucrose, and it was possible to examine the temperature elevation caused by ultrasound in the phantom. The suggested method was verified by noninvasively visualizing the temperature elevation due to planar and focused ultrasound using the fabricated phantom.

Self-Reconfiguration of Service-Oriented Application using Agent and ESB in Intelligent Robot (지능로봇에서 에이전트와 ESB를 사용한 서비스 지향 애플리케이션의 자가 재구성)

  • Lee, Jae-Jeong;Kim, Jin-Han;Lee, Chang-Ho;Lee, Byung-Jeong
    • Journal of KIISE:Computing Practices and Letters
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    • v.14 no.8
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    • pp.813-817
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    • 2008
  • Intelligent Robots (IR) get data of the current situation from sensors and perform knowledgeable services. Self-reconfiguration of IR is an important factor to change itself without stopping while supporting environment and technology change. In this paper, we propose an agent based self-reconfiguration framework of IR using ESB (Enterprise Service Bus). This framework focuses on dynamic discovery and reconfiguration of service-oriented applications using multi-agent system in intelligent robots. When IR meets an irresolvable situation it downloads a necessary service agent from an external service repository, executes the agent, and resolves the situation. Agent technology provides an intelligent approach for collaborations of IR. The prototype has also been implemented to show the validity of our study.

A Attendance-Absence Checking System using the Self-organizing Face Recognition (자기조직형 얼굴 인식에 의한 학생 출결 관리 시스템)

  • Lee, Woo-Beom
    • The Journal of the Korea Contents Association
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    • v.10 no.3
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    • pp.72-79
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    • 2010
  • A EAARS(Electronic Attendance-Absence Recording System) is the important LSS(Learning Support System) for blending a on-line learning in the face-to-face classroom. However, the EAARS based on the smart card can not identify a real owner of the checked card. Therefore, we develop the CS(Client-Sever) system that manages the attendance-absence checking automatically, which is used the self-organizing neural network for the face recognition. A client system creates the ID file by extracting the face feature, a server system analyzes the ID file sent from client system, and performs a student identification by using the Recognized weight file saved in Database. As a result, The proposed CS EAARS shows the 92% efficiency in the CS environment that includes the various face image database of the real classroom.

Effects of Social Support on Job Stress and Job Burnout : Focus on Luxury Hotel in Seoul (호텔구성원의 사회적지지에 대한 인식이 직무스트레스와 직무소진에 미치는 영향)

  • Lee, Sang-Woo
    • The Journal of the Korea Contents Association
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    • v.13 no.11
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    • pp.423-432
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    • 2013
  • It is very important to prevent and management negative sides in advance can occur in service transaction as an employee' attitude during service encounter has a decisive effect on customers' service evaluation. Work stress has become one of the most widely studied topics in research, mainly because of its importance to employees' psychological health, which in turn affects service quality and organizational effectiveness. This study aims to explore how social support that hotel employees perceive influence on job stress and job burnout. Data were collected from 355 hotel employees at Deluxe Hotel in Seoul, analyzed using structural equation modeling techniques. The findings are as follows Firstly, social support had a significant influence on job stress. Secondly, social support had a significant influence on job burnout. Thirdly, job stress had a significant influence on job burnout. To reduce job stress and job burnout recognition, self-esteem and motivation, the hotel need to deliver a stronger coaching program. In addition, for an organization to respond flexibly. Finally, the results were discussed in the context of providing the job burnout management for employee.

Measurement of Viscoelastic Constants from Multiple Phase MR Elastography Fitting Elastic Wave (탄성파를 적용한 다중 위상 MR Elastography로부터의 점탄성 정수의 측정)

  • Jung, Nam-Chae
    • Journal of the Institute of Convergence Signal Processing
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    • v.13 no.3
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    • pp.119-129
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    • 2012
  • In the medical field, the hardening of tissues is one of important informations used in diagnosis or understanding progress of disease, a quantitative measuring method of hardening is important for objective diagnosis. It has been proposed MRE(Magnetic Resonance Elastography) method that measures an index of hardening, viscoelastic properties in a noninvasive. Because the S/N ratio of MRE images go down when measuring viscoelastic properties from local wavelength and local damping factor of a propagating wave in MRE method, methods using multiple phase MRE images have been examined to decrease the effect of noise. We propose a method measuring viscoelastic properties after Fitting a function for multiple phase MRE images in this research. This proposed method has a advantage to set up arbitrarily the variation rate of a space direction of viscoelastic properties or the spatial resolution of measuring values according to changing of the noise included in images, though it applies viscoelastic wave for multiple phase MRE images. We confirmed the effectiveness of a proposed method by experiment using simulation images and experiment using silicone-gel phantom.

Machine Learning Process for the Prediction of the IT Asset Fault Recovery (IT자산 장애처리의 사전 예측을 위한 기계학습 프로세스)

  • Moon, Young-Joon;Rhew, Sung-Yul;Choi, Il-Woo
    • KIPS Transactions on Software and Data Engineering
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    • v.2 no.4
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    • pp.281-290
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    • 2013
  • The IT asset is a core part that supports the management objective of an organization, and the fast settlement of the IT asset fault is very important. In this study, a fault recovery prediction technique is proposed, which uses the existing fault data to address the IT asset fault. The proposed fault recovery prediction technique is as follows. First, the existing fault recovery data were pre-processed and classified by fault recovery type; second, a rule was established for the keyword mapping of the classified fault recovery types and reported data; and third, a machine learning process that allows the prediction of the fault recovery method based on the established rule was presented. To verify the effectiveness of the proposed machine learning process, company A's 33,000 computer fault data for the duration of six months were tested. The hit rate for fault recovery prediction was approximately 72%, and it increased to 81% via continuous machine learning.

The Effect of Leader's Machiavellianism on Turnover Intention: Mediating Effect of Hindsight Bias (리더의 마키아벨리즘이 이직의도에 미치는 영향: 후견지명의 매개효과)

  • Chung, Jaeyoung;Shin, Jegoo
    • Knowledge Management Research
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    • v.22 no.1
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    • pp.155-181
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    • 2021
  • The purpose of this study is to verify the correlation between leader's machiavellianism and turnover intention. To this end, we tried to investigate the overall mechanism of the research model through the mediating effect of hindsight bias. To verify the hypothesis, surveys were conducted twice with 335 employees working at companies with more than 300 employees in various occupations. As a result of the study, first, it was found that the machiavellianism of the leader had a positive significant effect on the employee turnover intention. Second, it was found that hindsight bias had a positive significant mediating effect between the leader's machiavellianism and employee turnover intention. It can be inferred that the higher the machiavellianism tendency of the leader, the higher the hindsight bias is experienced and the negative impact on the effectiveness of the organization, the higher the employee turnover intention. Therefore, this study in-depth verifies the mechanism between the leader's machiavellianism, hindsight bias, and employee turnover intentions, suggesting new implications from a perspective different from the existing research flow, and suggesting future research tasks and limitations on the role of leaders.

The Comparison of Efficacy and Safety between Radiofrequency Ablation Alone and Ethanol Ablation Followed by Radiofrequency Ablation in the Treatment of Mixed Cystic and Solid Thyroid Nodule (낭성 및 고형성 혼합 갑상선 결절 치료에서 고주파 절제술 단독요법과 에탄올 절제 후 고주파 절제술 요법의 유효성 및 안전성 비교)

  • Min Gang Jo;Min Kyoung Lee;Jae Ho Shin;Min Guk Seo;So Lyung Jung
    • Journal of the Korean Society of Radiology
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    • v.85 no.3
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    • pp.618-630
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    • 2024
  • Purpose To compare the efficacy and safety of radiofrequency ablation (RFA) and ethanol ablation (EA) followed by RFA in treating mixed cystic and solid thyroid nodules. Materials and Methods We included 243 nodules from 243 patients who underwent RFA for mixed cystic and solid benign nodules. The nodules were divided into two groups (RFA alone and EA + RFA). We evaluated volume reduction rate (VRR), therapeutic success rate, improvement in symptomatic and cosmetic issues, complications, and adverse effects. Results The RFA group included 204 patients, and the EA + RFA group included 39 patients. The long-term success rates in the RFA only and EA + RFA groups were 90.2% and 97.4%, respectively. The mean VRR at the last follow-up in the RFA and EA + RFA groups were 81.6% and 87.2%, respectively. Therapeutic results were similar in both groups at the last followup. Cosmetic and symptomatic problems markedly improved in both groups. No major complications were observed. Conclusion Both RFA alone and EA + RA are safe and effective methods for treating mixed cystic and solid thyroid nodules, although EA + RFA is slightly more effective.