• Journal of Sasang Constitutional Medicine
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• 제25권3호
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• pp.243-253
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• 2013

Objectives The aim of this study was to examine significant improvement of dizziness, gait disturbance, insomnia and xerostomia after treatment with Jowisengcheong-tang in a Taeeumin patient with olivopontocerebellar atrophy (OPCA). Methods The patient's subjective and objective symptoms were observed daily throughout the hospitalization period using global assessment (G/A), and the Unified Multiple System Atrophy Rating Scale (UMSARS) was used to assess the overall function of patient. Results The symptoms of dizziness and xerostomia decreased from G/A 100 to G/A 10~30 for five days, and the UMSARS score decreased in Part I,II. Conclusions This case showed that Sasang constitutional medicine treatment can be effective treatment method for OPCA. We consider that consistent treatment can contribute to improve the patient's quality of life.

• Journal of Acupuncture Research
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• 제22권3호
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• pp.145-153
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• 2005

Objective : This study was designed to investigate the effects and adverse effects of Choweseuncheng-tang on obesity patients Methods : Choweseuncheng-tang was given to 20 obesity patients who have no abnormality of GOT, GPT and past medical history. Additionally, electroacupuncture was performed on Fuchao(腑巢) with 60Hz. We compared body weight, body fat and laboratoy test(GOT, GPT, BUN, Creatinine) between before and after treatment. Blood pressure, heart rate and clinical symptoms were checked to investigate the side effects. Decrease of body weight was checked in accordance with Sasang constitutional type, appetite type, and BMI. Results : 6 patients(BMI 23-24.9), 10 patiets(BMI 25-29.9), and 4 patients(BMI over 30) were showed decrease of body weight. We found body fat was decerased $3.16{\pm}1.25%$. BUN, Creatinine, GOT and GPT were increased within normal range. There were adverse event of autonomic hyperactivity(11 patients), gastrointestinal symptoms(7 patients) and others(3 patients). Conclusions : According to above results, Choweseuncheng-tang could be used effectively, but should be taken cautiously on obese patients.

• The Journal of Korean Obstetrics and Gynecology
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• 제26권2호
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• pp.178-187
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• 2013

Objectives: These cases are that of three girls who are diagnosed as precocious puberty. It seems that the incidence of precocious puberty is rapidly increasing these days. In addition to the psychosocial disturbances associated with precocious puberty, the premature pubertal growth spurt and the accelerated bone maturation result in reduced adult height. The aim of this study was to report the effect of Jowisengchung-tang in 3 cases of precocious puberty. Methods: Retrospective and comparative analysis of 3 children who had been diagnosed with preco cious puberty. Anthropometric measurements including height, weight, body fat, body fat percent, AHP and body mass index were measured. Endocrine investigations including estradiol, luteinizing hormone(LH), FSH were conducted. Pubertal stages were determined with a questionnaire using Tanner stages. Jowisengchung-tang was given to 3 precocious puberty girls. Results: After treatment, the hormone(estradiol index) and accompanying symptoms (breast bud with elevation of breast and papilla; enlargement of areola) were reduced compared with first visit day. Conclusions: We may conclude that Korean traditional treatment of Jowisengchung-tang is effective in patients with precocious puberty and menopausal symptoms.

• Journal of Oriental Neuropsychiatry
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• 제19권3호
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• pp.205-217
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• 2008

After recovery from acute carbon monoxide poisoning, some patients suffer from neuropsychiatric problems such as cognitive impairement, movement disorder, change of personality and mental disorder after lucid interval in which the patient has no symptom. This sequela of carbon monoxide poisoning is called delayed post-anoxic encephalopathy(DPE). No neuroprotective drug has yet demonstrated ecfficacy and hyperbaric oxygen treatment's effect have little scientific evidence in preventing and improving DPE. In such situation, korean traditional treatment may be helpful in treating the patient suffering from DPE. In this case report, we will describe the patient that has suffered from severe DPE involving cognitive impairment, gait disturbance and incontinence but has been improved successfully by korean traditional medicine treatment, especially Jowiseungchungtang. This case could present how we will study about DPE.

• The Journal of Pediatrics of Korean Medicine
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• 제15권2호
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• pp.43-51
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• 2001

Background : In recent years, obese patient have increased, but there were a few clinical report of herb &acupunture of the obesity. Objective : The aim of this study was to report the effect of Kamijowisengchungtang &Acupunture in 66 cases of obese patient. Material and Method : The clinical study were done on 66 cases of obese patients who were treated by Kamijowisengchungtang &Acupunture in Dept. of Oriental Medicine Kunsan Medical Center from February 2000 to May 2000 Result : After treatment, the weight was reducted statistically from $70.14{\pm}10.69kg\;to\;66.26{\pm}10.37kg$. Conclusion : We know that Kamijowisengchungtang &Acupunture Therapy is effective treatment in obese patient.

• The Journal of Korean Oriental Chronic Disease
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• 제10권1호
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• pp.39-45
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• 2005

Objectives It is the case study of a critically ill patient with cerebral infarction and acute edematous change at femur due to a hematoma, of whom taken care with herb medicine according to the diagnosis of SCM(Sasang Constitutional Medicine). Methods The syndrome of the patient was diagnosed as a superficial disease of Taeumin. So after the on-set of the femoral edema, Jowiseungchung-tang added Castanea mollissima(Gunyul) and Maladera castanea(Jejo) was used. And we checked the change of the circumferencial size her thigh and followed up the sonography. Results and conclusions The therapy was significantly effective, and the edema was rapidly absorbed. The circumferential size was 83cm at on-set time, but got smaller to 57cm almost same to the healthy side of her thigh, and there was no more hematoma or systemic hemorrhagic sign on the body.

• Journal of Sasang Constitutional Medicine
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• 제14권1호
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• pp.100-111
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• 2002

1. The Purpose of study An experimental study has done to examine the effect of defense on gastric mucosal damage of Jowesungcheong-tang. 2. The Material and Method of study Mice had intragastric injected with JST extract before indome thacin treatment which induces hemorrh age erosion artificially. General morphology, infiltrative cell in mucosa, the distribution of UEA-I, COX-1, MAC-1. ICAM, and Apoptotic cell were objected (Ahhreviation) JST :Jowesungcheong-tang, UEA-I : ulex europaeus agglutinin-I, COX-1: cyclooxyhenase-1, ICAM : intercellular adhesion molecule-1, GPE : Gastropathy elicitated mice 3. The results and Conclusions of study 1) The degree of hemorrhage erosion in GPE-group had increased conspicuously in gastric gland proper. JST -group were the same as normal 2) The noticeable increase of granular lecocytes and lymphocytes in GEP-group were seen, but in JST group, the configuration is decreased 3) The decrease of UEA-I positive reacted cells, COX-1, surface epithelial cells and the increase of MAC-l positive cells, ICAM-l positive cells had shown in GPE-group, but in JST-group UEA-I positive cells, COX-1 surface epithelial cells were in creased and MAC-1 positive cells, ICAM-l positive cells were decreased than GPE-group. 4) A number of apoptotic cells were distributed in hemorrhage erosion. The remarkable decrease of apoptotic cells were shown in JST-group.

• Journal of Sasang Constitutional Medicine
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• 제14권1호
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• pp.67-78
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• 2002

Jowiseungcheongtang(JST) has been in Sasang constitution medicine for many years as a therapeutic agent for cerebral disease. But the effect of Jowiseungcheongtang(JST) on neurotoxicity is not known. The purpose of this study was to determine the effects of Jowiseungcheongtang(JST) on the hippocampal cell injured by Xanthine Oxidase/Hypoxanthine. The results were as follows: 1. XO/HX decreased the survival rate of the cultured hippocampal cells on NR assay and MTT assay. 2. JST water extract have efficacy of decreasing a amount of lipid peroxidation increased by XO/HX in cultured hippocampal cells. 3. JST water extract have efficacy of increasing DNA synthesis decreased by XO/HX in cultured hippocampal cells. From the above results, It is concluded that JST has marked efficacy in preventing cultured hippocampal cells from the damages by XO/HX.

• Journal of Oriental Neuropsychiatry
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• 제8권1호
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• pp.69-79
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• 1997

This study was conducted to find out the effects of Jowiseungchungtang on learning and memory of rats. For this purpose, the radial-arm maze was used. The results of the study were summarized as follows.1. It was shown that the rate of rats that met the learning criteria when performing the learning is that the control group amounted to 40.0% while the Jowiseungchungtang group did 73.3%. The other showed higher learning effect than the one but there was no statistical significance.2. In the retention test performed with rats that met the learning criteria, the frequency of errors made by the two groups was 3.33$\pm$2.25 times for the control group and 1.36$\pm$1.12 times for Jowisrungchungtang group. The other was remarkably lower than the one in the frequency of errors.In conclusion, the study suggested that the Jowiseungchungtang have an effect on improvement of learning and memory.

• Korean Journal of Pharmacognosy
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• 제17권1호
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• pp.12-18
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• 1986

In order to investigate experimentally the clinical effects of Choweesungchung-Tang that has been widely used in the cardiovascular and neuropsychogenic disease, experimental studies with experimental animals were carried out. The results of these studies were summarized as follows; Suppressive action was not shown on the convulsion induced by strychnine, but significant effect was noted on the convulsion induced by picrotoxin and caffeine. In acetic acid method, analgesic effect was noted. By the rotor rod and wheel cage method, sedative action was noted. A prolongation of hypnotic time induced by pentobarbital-Na was obtained. Relaxing action was noted remarkably on the ileum of mice, also about mice and guinea-pigs, the same effect was recognized on the smooth muscle of the ileum. The expansion of blood vessels by relaxation of smooth muscle and hypotensive action were noted.