DOI QR코드

DOI QR Code

A Report on the Effect of Jowisengchung-tang in 2 Cases of Precocious Puberty

조위승청탕(調胃升淸湯)을 투여한 성조숙 증상을 주소로 한 여아의 한방치료 2례

  • 김지은 (동신대학교 한의과대학 부인과 교실) ;
  • 양승정 (동신대학교 한의과대학 부인과 교실) ;
  • 조성희 (동신대학교 한의과대학 부인과 교실) ;
  • 박경미 (동신대학교 한의과대학 부인과 교실)
  • Received : 2013.04.26
  • Accepted : 2013.05.09
  • Published : 2013.05.31

Abstract

Objectives: These cases are that of three girls who are diagnosed as precocious puberty. It seems that the incidence of precocious puberty is rapidly increasing these days. In addition to the psychosocial disturbances associated with precocious puberty, the premature pubertal growth spurt and the accelerated bone maturation result in reduced adult height. The aim of this study was to report the effect of Jowisengchung-tang in 3 cases of precocious puberty. Methods: Retrospective and comparative analysis of 3 children who had been diagnosed with preco cious puberty. Anthropometric measurements including height, weight, body fat, body fat percent, AHP and body mass index were measured. Endocrine investigations including estradiol, luteinizing hormone(LH), FSH were conducted. Pubertal stages were determined with a questionnaire using Tanner stages. Jowisengchung-tang was given to 3 precocious puberty girls. Results: After treatment, the hormone(estradiol index) and accompanying symptoms (breast bud with elevation of breast and papilla; enlargement of areola) were reduced compared with first visit day. Conclusions: We may conclude that Korean traditional treatment of Jowisengchung-tang is effective in patients with precocious puberty and menopausal symptoms.

Keywords

References

  1. Korean Society of Pediatric Endocrinology. Pediatric endocrinology. 2nd ed. Seoul: Kwangmoon Publishing Co. 2004:242-279.
  2. Mi Jung Park. Recent Advance in Pathogenesis and Treatment of Precocious Precocity. Korean Journal of Pediatrics. 2006;49(7):18-725. https://doi.org/10.3345/kjp.2006.49.1.18
  3. 서병규. 성조숙증의 진단과 치료. 대한소아과학회지. 2001;44:607-613.
  4. Health education forum. Menarche in Korea Women. 2009.
  5. 이민정 등. 성조숙증性早熟證에 관한 연구의 최근 동향-최근중의 잡지를 중심으로-. 대한한방소아과학회지. 2008; 22(1):163-187.
  6. 전국 한의과대학 사상의학교실. 개정 증보 사상의학. 서울:집문당. 2008:712.
  7. 김호철. 한방약리학. 서울:집문당. 2004:63-66
  8. 신현정 등. 초음파를 이용한 골연령의 측정. 대한소아내분비학회지. 2006;11(1): 93-97.
  9. 김호성. 성조숙증의 진단과 최신 치료 경향. 대한내분비학회지. 2008;23(3):165
  10. 대한한방부인과학회 편저. 한방여성의학(상). 서울:의성당. 2012:198.
  11. 헬스조선 편집부. 우리 아이 키 정상적으로 크고 있나. 서울:헬스조선. 2008: 50-57.
  12. 건강보험심사평가원 심사평가연구소 연구조정실. 조기발견 중요한 성조숙 증, 혹시 내 아이도? 건강보험심사평가원 보도자료. 2011.
  13. Lakshman, R. et al. Association between age at menarche and risk of diabetes in adualts: Results from the EPICNorefolk cohort study. Diabetologia. 2008;51:781-786. https://doi.org/10.1007/s00125-008-0948-5
  14. Kampert JB, Whittemore AS, Paffenbarger Jr RS. Combined effects of childbearing, mensturual events, and body size on age-specific breast cancer risk. American Journal of Epidemiology. 1998;128: 62-979.
  15. 박미정. 성장클리닉의 실제. 가정의학회지. 2006;27(11):596-599.
  16. Wassim C, et al. Central precocious puberty: clinical and laboratory features. Clin Endocrinol. 2001;54:289-294. https://doi.org/10.1046/j.1365-2265.2001.01229.x
  17. Paul K. Clinical characteristics of 104 children referred for evaluation of precocious puberty. J Clin Endocrinol Metab. 2004;89:3644-3650. https://doi.org/10.1210/jc.2003-031532
  18. Lee PA. Advances in the management of precocious puberty. Cin Pediatr. 1994;33:54-61.
  19. Kappy MS, Ganong CS. Advances in the treatment of precocious puberty. Adv Pediatr. 1994;41:1286-1290.
  20. 전국한의과대학 원전학교실. 현토교감 조본황제내경소문. 서울:집문당. 2010.
  21. 劉慧丽, 柳靜. 從肝腎論治女童性早熟. 北京中醫. 2006;25(2):90-91.
  22. 高華. 柳云鵬治療女童特發性性早熟經 驗. 湖北中醫雜誌. 2004;26(12):13-14.
  23. 李海浪, 郑意楠, 蔡德培. 滋陰瀉火中 藥治 療女孩特發性眞性性早熟. 铁道醫學. 1999;27(2):101-102.
  24. 陳小平, 李海浪, 鄭意楠. 滋陰瀉火中 藥爲主治療女特發性性早熟的臨床分析. 中國當代兒科雜誌. 2007;9(3):249-250.
  25. 蔡德培, 李志英, 時毓民. 滋陰瀉火中 藥及甲地孕酮 治療 女性 特發性 性 早熟的 臨床硏究. 中國中西醫結合雜誌. 2001;21(10):732-735.
  26. Lim JS. Changes and Their Correlations of Body Compositions and Serum Leptin Concentrations according to the Healthy Children and Adolescents. Seoul National University. Seoul.2002.
  27. Car JF et al. Leptin: the tale of an obesity gene. Diabetes. 1996;45(11): 1455-1462. https://doi.org/10.2337/diab.45.11.1455
  28. 한주원 등. 감비 2호방이 고지방식이로 유도된 비만 생쥐에 미치는 영향. 동의생리병릭학회지. 2009;23(4):837-847.
  29. 권미원 등. 조위승청탕과 배수혈 침구치료를 통한 비만환자 66례의 임상적 보고. 대한한방소아과학회지. 2001; 15(2):43-51.
  30. 김기훈 등. 특발성 진성 성조숙증으로 진단된 소아의 원인 및 임상적 분석. 대한한방소아과학회지. 2011;25(2)11:1-120.

Cited by

  1. A Case Report of Efficacy of Growth Height and Peak-Luteinizing Hormone Level Suppression on Idiopathic Gonadotropin-Dependent Precocious Puberty Patient Using Herbal Remedy, vol.36, pp.4, 2015, https://doi.org/10.13048/jkm.15042
  2. A Study of the Characteristics of the HRV of the Girl Showing a Precocious Puberty vol.29, pp.3, 2016, https://doi.org/10.15204/jkobgy.2016.29.3.010
  3. A Case Report of Precocious Puberty in a Female Patient : Significant Improvement in Controlling the Sex Hormone Levels vol.28, pp.4, 2014, https://doi.org/10.7778/jpkm.2014.28.4.064
  4. 성조숙증 치료에 대한 임상 연구 동향 -최근 중의학 저널을 중심으로- vol.31, pp.1, 2017, https://doi.org/10.7778/jpkm.2017.31.1.063
  5. 특발성 성조숙증으로 진단받은 환아 2례에 대한 증례보고 vol.31, pp.1, 2013, https://doi.org/10.7778/jpkm.2017.31.1.074
  6. 빠른 2차 성징이 우려되는 여아에 대한 사상의학적 치험 5례 vol.29, pp.2, 2017, https://doi.org/10.7730/jscm.2017.29.2.174
  7. 한약 치료를 이용한 여성 특발성 성조숙증의 임상연구에 대한 문헌고찰 vol.30, pp.3, 2013, https://doi.org/10.15204/jkobgy.2017.30.3.020