• Title/Summary/Keyword: 정신과약물

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EVALUATION OF THE THERAPEUTIC EFFECTS OF CARBAMAZEPINE IN AUTISTIC CHILDREN (자폐증 아동에 있어서 Carbamazepine의 치료효과 평가)

  • Hong, Kang-E;Choi, Jin-Sook;Shin, Min-Sup;Hwang, Yong-Seung;Ahn, Yun-Ok
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.2 no.1
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    • pp.87-96
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    • 1991
  • A double bhad, placebo controlled study was performed to evaluate the therapeutic effects of Carbamazepine in autistic children, 23 boys with the diagnosis of Pervasive Developmental Disorders according to the DSM-IIIR were selected for study subjects, from Child and Adolescent Psychiatric Outpatient Department of Seoul National University Children Hospital during Oct. $1989{\sim}Nov.$ 1991. Subjects with histories of medical disease or psychiatric diseases were excluded and all study subjects had drug free periods more than 2 Months. Study subjects were randomly assigned to Cabamazepine treatment group(N=12) and placebo group(N=11). After the baseline observation periods, the double blind drug treatment and observation were performed for 12 weeks. Several scales (Ritvo-Freedman Real Life atring Scale. Behavior Checklist) were employed to evaluate the effects of drug treatment during baseline observation periods and the drug treatment periods by two raters blind to the study. Interrater reliability of each scales were .4875~.6613, the socrodemographic variables and the rating scores during baseline observation periods were not significantly different between two groups. Reduction of total scores in Autsm Behavior Checklist scale, i.e.. improvement of global autistic symptoms were noted significantly in Carbamazepine treatment group. Improvement in significant social maturations according to Vineland Social Mataration scale were observed in both patient groups after drug treetment periods.

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An Experimental Study on the Nursing Therapy as a Emotional Crisis Intervention of the Psychiatric Emergency Patient (정신과 응급환자의 위기 해결로서의 간호치료에 관한 실험적 연구)

  • Kim, Chung-In
    • Journal of Korean Academy of Nursing
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    • v.5 no.1
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    • pp.48-58
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    • 1975
  • 대부분의 정신과적 위기 (자살시도.도주 공격적 파괴적행동.싸움 등)는 노여움이 원인이 되는데 심한 불안. 초초나 또는 규칙등을 위반하였을 때에. 고지식한 병원직원들의 마구 다툼에 의해서 자신의 권리나 존엄성을 모욕 받았다고 생각될 때 그것에 대한 반응으로 일어나게 된다. 이러한 환자들의 흥분및 공격적 파괴적 행동들에 대해서 우리 간호원들은 과연 겁내야 하며 곧 진정제를 투여하거나 강박의를 입혀야 하는가 하는 것이 이 연구의 촛점이다. 본인은 이러한 환자들의 위기상황에 성급한 행동들이 주어지기에 앞서 과학적이고 체계적인 간호적 이해가 따른다면 환자들의 태도는 휠씬 달라질 수 있을 것이라는 가정하에 국립정신 병원에서 1973년 6월 1일부터 9월30일까지 실험군 10명. 통제군 10명의 환자에게 관찰기 (5일). 간호기(5일). 후반기 (5일)로 나누어 실험군에는 간호기에 유효적절한 과학적 체계적 간호를 실시하고. 통제군에는 실시하지 않음으로써 그 효과도를 검증하였다. 환자의 치료에는 간호적 치료이외에도 약물요법, 정신치료. 충격요법 등 관계 요인이 많으므로. 이러한 기간동안의 환자의 행동변화가 간호적 치료 (Nursing Therapy)에 의해 변화된 것인가를 확인하기 위해 검증하였다. 그 결과는 다음과 같다. (P<.01) 표6. 7에서 관찰기. 간호기. 후반기 동안의 정신과 응급 행동의 빈도는, 실험군에서는 15.4. 7.0. 2.9 로 감소되어 p <.01의 수준에서 의미 있는 변화임이 밝혀졌고, 통제군에서는 10.6. 6.9. 6.6으로 행동빈도가 감소되었으나 p >.05의 수준에서 의미 있는 변화가 아님을 보이고 있다. 위의 결과들로 미루어 본 연구는 다음과 같은 결론을 내릴 수 있을 것이라고 생각한다. \circled1환자의 위기 행동에 관한 사전의 이해없이 무조건의 안정제 투여와 강박의 사용은 금해야 할 것이다. \circled2유효 적절한 자학적 체계적 간호치료 (Scientific & Systematic Nursing Therapy 로서 정신과적 위기는 해 결될 수 있을 것이다. \circled3간호원은 치료적 요원의 역할을 담당할 수 있을 것이다. 본 논문을 시종 지도하여 주신 이부영선생님과 조언을 주신 이은옥 선생님. 이귀향 선생님. 그리고 국립정신병원의 김종해선생님, 보건대학원의 이영환 선생님께 진심으로 감사를 드리며. 아울러, 실험에 협력하여 주신 모든 분들께도 감사를 드립니다.

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A CASE OF CLOZAPINE TRIAL FOR A MANIC EPISODE SUFFERED BY AN ADOLESCENT RECOVERING FROM NEUROLEPTIC MALIGNANT SYNDROME (신경이완제 악성증후군 회복후 지속되는 조증에 Clozapine을 사용한 청소년 환자 1례)

  • Cho, Soo-Churl;Hong, Kang-E;Kim, Yong-Sik;Chung, Sun-Ju;Bahn, Geon-Ho
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.9 no.2
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    • pp.247-252
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    • 1998
  • Neuroleptic malignant syndrome(NMS) is an acute, potentially fatal, idiosyncratic reaction to neuroleptic medication. Early recognition and intensive care are crucial. An important issue is whether NMS will recur after initial recovery and subsequent use of neuroleptic medication. The authors presented with a male adolescent who had suffered a bipolar disorder manic episode and been taking clozapine after recovering from MNS. He had been admitted into a psychiatric ward once before and similarly diagnosed. On the second admission, he showed muscle rigidity, autonomic instability, mild fever, severe diaphoresis, and altered mental status on the fourth hospital day following a haloperidol injection. He was diagnosed with NMS, according to the clinical signs and laboratory data. After the use of antipsychotics was discontinued, he was moved to intensive care unit and given dantrolene. His condition began to improve about 48 hours after the onset of NMS. Due to manic behavior, he returned to the psychiatric ward. On the 21 st hospital day, clozapine was administered to counter the manic symptoms. The final dose was 350mg and showed good remission signs without further recurrence of NMS.

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THERAPEUTIC APPROACH FOR CHILD AND ADOLESCENT AFTER DISASTER (재해를 당한 소아청소년에 대한 치료적 접근)

  • Lee, Young-Sik
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.13 no.1
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    • pp.24-29
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    • 2002
  • The social attention about disaster psychiatry was increased after 911 terror in New York. The role of child psychiatrist and specific consideration for the treatment of child victim in disaster were reviewed. The following were main points. 1) The most single determining factor of prognosis is supporting system and parental attitude to their child victim. So family therapy and parental eucation are needed. 2) Cognitive Behavior Therapy is known to the most effective treatment in many literature. 3) Brief group therapy with fellow victim is cost effective preventive methods and screening tool for more serious victim, 4) Eye Movement Desensitization and Reprocessing(EMDR) could be a very amazing method in reducing repetative horrible traumatic image. 5) Many kinds of drug using in adult are considered with caution.

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Anger and Social Support of Elderly Women (여성노인의 분노와 사회적 지지)

  • Ko, Sung-Hee;Kim, Hyun-Kyung;Chin, Eun-Young
    • The Journal of the Korea Contents Association
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    • v.13 no.6
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    • pp.300-308
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    • 2013
  • The purpose of this study was to explore the level of anger and social support and to identify factors affecting anger in elderly women. This was a cross-sectional descriptive survey. A convenience sample of 155 elderly women was recruited from two senior welfare centers and three nursing homes in J city. Data were collected from June 15 to July 15, 2010 through interviews using a structured questionnaire. Data were analyzed with descriptive statistics, independent t-test, one-way ANOVA, Pearson's correlation coefficient, and multiple linear regression using the SPSS WIN 18.0 program. The level of social support and anger was 3.73 and 2.72 out of 5, respectively. Anger was statistically significantly different according to type of residence (B=0.21, t=2.42, ${\rho}$=.017), psychiatric medication (B=0.66, t=4.93, ${\rho}$ <.001), physical medication (B=0.41, t=4.22, ${\rho}$ <.001), and evaluation support (B=-0.15, t=-3.00, ${\rho}$=.004), and these accounted 33.0% of anger. Providing proper information and developing social support program would be useful for managing anger of elderly women.

A Case of a Panic Disorder(with Agoraphobia) Patient Improved by Herbal Extracts - Gyejigayonggolmoryo-tang(Guizhijialonggumuli-tang) and Jakyakgamcho-tang(Shaoyaogancao-tang) - (한약(韓藥) Extract 제제의 투여로 호전을 보인 광장공포증을 동반한 공황장애 환자 1례(例) - 계지가용골모려탕(桂枝加龍骨牡蠣湯)과 작약감초탕(芍藥甘草湯) -)

  • Suh, Hyun-Uk;Hwang, Eun-Young;Jung, Sun-Young;Kim, Jong-Woo
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.4
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    • pp.207-218
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    • 2010
  • Objectives : This case report presents a 33-year-old male patient who complained chest pain and anxiety. diagnosed with panic disorder with agoraphobia improved by Herbal Extracts. SRP(Stress Reduction Program) and Acupuncture treatment. Methods : In early treatment period. we evaluated his general psychological state through interview and self-questionnaires(STAI, SCL-90-R, STAXI, BDI) for treatment planing. And then we had prescribed herbal extracts for 20 weeks with applying SRP and acupuncture treatment. After 20 weeks we assessed his psychological symptoms with same evaluation tools. Results : After 20 weeks. We found that patient's somatic and psychological symptoms(anxiety, depression, anger) were alleviated. Frequency and severity of panic attacks were reduced also. Conclusions : Herbal extracts. especially Gyejigayonggolmoryo-tang(桂枝加龍骨牡蠣湯) and Jakyakgamcho-tang(芍藥甘草湯), may be useful therapeutic tool for control of panic attack symptoms and anxiety.

A Case with Delirium during Medication for Hallucination and Disorientation (환각 및 지남력 저하에 대한 약물치료 중 발생한 섬망 환자 1례(例) 증례보고)

  • Choi, Eun-Young;Seok, Seon-Hee;Kim, Geun-Woo;Koo, Byung-Soo;Kim, Joo-Ho
    • Journal of Oriental Neuropsychiatry
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    • v.17 no.2
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    • pp.227-235
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    • 2006
  • Delirium is a acute syndrome of disorientation caused by dysfunction of brain tissue and has a many varied symptom. The characteristic symptoms of delirium are conscious disturbance with disorientation and dys-mnesia and emotional disturbance. We experienced a 77 year-old male who had a hallucination and disorientation as well as delirium caused by antipsychotic medication, and whose condition was improved through discontinuing medication and traditional Korean medical treatment. We had given herb medication, acupuncture treatment and decreased medication to this patient, and observed. The patient's delirium symptom ad improved through oriental medical treatment and decreasing medication. It was able to improve a delirium caused by not specified origin and side effect of drug abuse through oriental medical treatment and decreasing medication.

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Korean Medical Treatment and Language Therapy in Patient with Fluent Aphasia after Stroke : Case Report (한방치료 및 언어치료를 병행한 중풍 유창성 실어증 환자 치험 1례)

  • Yeo, Jin-Ju;Jang, In-Soo;Yoo, Gyung;Jeong, Eun-Hee;Kim, Lak-Hyung
    • Journal of Oriental Neuropsychiatry
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    • v.17 no.1
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    • pp.137-143
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    • 2006
  • In this study, we evaluated the effects of herbal medicine, acupuncture and language therapy in a patient with fluent aphasia after stroke. We treated the patient with Jihwangumja, special acupuncture points and Language-Oriented Treatment(LOT). The language abilities of the patient in this study was markedly increased in Korean-Western Aphasia Battery(K-WAB) and Communicative Ability in Daily Living Test(CADLT). Aphasia quotient, fluency, comprehension, repetition and naming score of K-WAB were improved in second and third examination compared with those of the first examination. Each item of CADLT was improved in second examination compared with that of the first examination.

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Neuroprotective Effect of Yukmijihwamg-tang(Liuweidihuangtang) Gamibang on the Deficits of Learning and Memory in Trimethyltin-Intoxicated Rats (트리메틸틴에 의해 유도된 흰쥐의 학습과 기억력 손상에 대한 육미지황탕가미방의 신경보호 효과)

  • Jeung, Hee-Sang;Kim, Geun-Woo;Koo, Byung-Soo
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.1
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    • pp.75-87
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    • 2009
  • 목적 : 이 연구는 알쯔하이머 병에 대한 육미지황가미방의 효과를 조사하였다. 육미지황가미방은 산약, 산수유, 복령, 목단피, 구기자, 택사, 숙지황을 포함한 여러 가지 한약재의 전탕액으로 치매의 한약 치료제로 널리 사용되어 왔다. 방법 : 이 약물의 신경보호 작용을 조사하기 위해, 수중미로를 사용하여 학습과 기억에 대한 육미지황가미방의 효과를 평가 했고, 트리메틸틴은 강력한 유독물질로 선택적으로 중추신경계와 면역계의 세포를 파괴시킨다. 트리메틸틴(6.0 mg/kg, i.p.)주입 후, 쥐에게 육미지황가미방(400mg/kg, p.o.)를 2주 동안 날마다 복용시켰으며, 수중미로를 수행시켰다. 결과 : 육미지황가미방을 트리메틸틴에 노출시킨 쥐에 투약했으며, 그들은 수중미로에서 학습과 기억의 향상을 보였고, 이는 육미지황가미방이 어떠한 환경에서는 트리메틸틴으로 유발된 신경퇴화 후 중추신경계의 결손을 감소시킬 수 있음을 보여준다. 결론 : 이러한 결론은 육미지황가미방이 인지능력을 증가시키고, 트리메틸틴으로 유발된 신경퇴화에서 콜린 아세틸전환효소의 정도를 변화시킬 수 있음을 보여준다.

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Case Report of Unspecified Tremor with Xerostomia Resulting from Psychometric Drug Intake Treated by Traditional Korean Medicine (한방치료로 호전된 상세불명의 떨림과 동반된 정신과계통 약물유발성 구강건조증 치험 1례)

  • Jung, Yu-jin;Kim, Minserh;Hong, Sang-hoon
    • The Journal of Internal Korean Medicine
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    • v.39 no.5
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    • pp.914-928
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    • 2018
  • Objectives: This case report examines the effects of traditional Korean medicine for unspecified tremor with xerostomia caused by psychometric drug intake. Methods: A patient who suffered from unspecified tremor with xerostomia caused by psychometric drug intake was treated with acupuncture, pharmacopuncture, and traditional Korean medicine for 30 days. We provided the patient with herbal medicines including Ondam-tang-gagam (溫膽湯加減), Pumsimgieum-gagam (忿心氣陰加減), and Hoichunyanggyeok-san-gami (回春凉隔散加味). Symptoms were charted and evaluated using the Yin-deficiency questionnaire score, Yin-deficiency scale score, dry mouth symptom questionnaire, and visual analogue scale. Results: After treatment with Korean Medicine and pharmacopuncture, the frequency and degree of tremor has decreased, and degree of Xerostomia also improved. The Scores of Yin-deficiency questionnaire score, Yin-deficiency scale score, dry mouth symptom questionnaire, and visual analogue scale were also improved. And we could see reduction in the level of distribution of gastrointestinal heat at Digital Infrared Thermal Imaging test. The patient's Symtoms (Xerostomia as well as unspecified tremor) were improved after treated with Korean Medicine and pharmacopuncture. Conclusion: Korean medicine treatments may be valuable for xerostomia caused by psychometric drug intake.