• 한국신재생에너지학회:학술대회논문집
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• 2010.11a
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• pp.121.2-121.2
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• 2010

제주도는 지질학적으로 제4기에 형성된 화산섬으로 지금까지 고온의 지열징후는 보고된 바 없으나, 남한에서 가장 최근까지 화산활동이 있었던 것으로 기록되어 있어 화산활동과 관련된 심부 지열자원 부존 가능성은 아직 열려있다고 할 수 있다. 본 연구에서는 제주도에서 지열부존 가능성을 타진하고 제주도 심부 지질구조 파악을 목적으로 2차원 및 3차원 자기지전류 (MT) 탐사를 수행하였다. 탐사는 중산간지역에서 한라산을 중심으로 동, 서, 남, 북의 4방향 4측선과 제주 서부지역에 남북방향의 1측선을의 총 5개 측선에 대해 수행하였으며, 이에 대한 MT 탐사자료의 2차원 및 3차원 역산을 통하여 한라산 하부 및 주변의 심부 지질구조를 파악하고자 하였다. 역산 해석 결과는 천부 구조는 기존 시추조사 결과 밝혀진 층서구조의 형태를 잘 나타내어 획득된 자료의 신뢰도가 높음을 지시하였다. 즉, 제주도 최 상부를 피복하고 있는 현무암 등의 화산암류는 고비저항(수백 ohm-m)으로, 그 하부의 해성 미고결퇴적층(U층 및 서귀포층)은 저비저항으로, 그리고 최하부의 응회암이나 화강암으로 구성된 기반암은 1,000 ohm-m 이상의 고비저항 층으로 잘 구분되어 나타났다. 특히, 제주도에서 특징적으로 해수면 하부 수십 ~ 수백 m에 존재하는 것으로 알려진 미고결퇴적층이 10 ohm-m 내외로 측선 전반에 걸쳐 나타났다. 이는 기존의 시추결과에서 미고결 퇴적층이 제주도 전역에 걸쳐 해수면 하부 100 m 내외의 심도에서 관찰되는 것과 일치하는 결과이다. 기반암 하부에서는 특징적으로 모든 측선의 중앙부에서 저비저항 이상대가 영상화되었으며 이는 2차원 역산과 3차원 역산해석에서 공통적으로 나타났다. 특히, 3차원 해석에서는 이러한 저비저항 이상대가 한라산 정상에서 서북쪽 부근에 나타나는데 이는 과거의 화산활동과 관련된 지질학적인 구조에 의한 영향일 가능성과 측선의 양단과 중앙에서 주변 바다의 영향이 다르게 나타나기 때문일 가능성으로 볼 수 있다. 즉, 전자는 심부에 발단된 각각의 파쇄대가 모든 측선의 중앙부에서 교차하거나 이를 통한 한라산의 생성과정과 연관된 지질학적인 구조일 가능성을 의미한다. 만약 한라산을 형성한 화성활동의 영향이 아직 지하 심부에 남아있다면 지열수의 부존 혹은 마그마의 통로가 되었을 단층의 영향으로 한라산 하부에 저비저항 이상대로 나타날 가능성이 높다. 그러나 후자에 의한 가능성도 배제할 수는 없으므로 향후 주변바다에 대한 영향을 고려한 3차원 역산해석이나 심부시추 등을 통한 상세한 지질조사 등 추가적인 연구가 이루어져야 할 것으로 판단된다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.9 no.1
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• pp.98-104
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• 1998

A 12-year-old girl with a 6 year history of childhood-onset schizophrenia required 2 hospitalizations and long-term clozapine trial due to inadequate responses to combinations of typical neuroleptics and traditional treatments of schizophrenic disorder. On admission, she had continuous auditory and visual hallucinations, persecutory delusion, emotional instability, regression of behaviors including temper tantrums as well as specific developmental delays in learning, language, and motor coordination. The clozapine trial significantly reduced most of the positive symptoms, and facilitated in successful discharge from the hospital. During the 4 year clozapine treatment, no significant adverse reactions were noted, and she returned to a structured school setting with minimal degrees of schizophrenic symptoms. From this clinical experience, we suggest that clozapine might be safe and effective in treating treatment-refractory schizophrenic children.

• Proceedings of the KIEE Conference
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• 2008.10c
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• pp.15-17
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• 2008

전동차용 견인전동기 시스템은 저항 및 쵸퍼 제어에 의한 직류 전동기 방식에서 인버터 제어에 의한 유도전동기 방식으로 발전하였다. 오늘날 유도전동기 기술은 어느 정도 성숙기에 접어들었지만 최근에는 소음 제거, 효율 극대화 및 유지보수 비용 절감 등의 이점이 있는 감속기를 제거한 직접 구동용 영구자석 전동기가 새로이 각광받고 있다. 따라서 본 논문에서는 자기적 포화특성이 심한 영구자석 전동기를 대상으로 비선형 수치 해석 기법을 적용하여 운전조건별 특성해석 및 설계기술에 대해 나타내었다.

• Proceedings of the KIEE Conference
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• 1999.07a
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• pp.3-5
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• 1999

The 4-pole LHSM was composed of the figure-of-eight shaped 3-phase armature windings, DC field windings, and the segmented secondary with the transverse bar track. Three dimensional model of LHSM provided the equivalent reluctance and PM model for 2D FEA. From these 2D FEA models, when the motor was fed by DC and 3-phase currents, the magnetic field were calculated and compared with the results of 3D FEA.

• Journal of Astronomy and Space Sciences
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• v.24 no.2
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• pp.125-134
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• 2007

In this paper, we analyze the orbital variation of the Korea Multi-Purpose SATellite-1(KOMPSAT-1) in a strong space environment due to satellite drag by solar and geomagnetic activities. The satellite drag usually occurs slowly, but becomes serious satellite drag when the space environment suddenly changes via strong solar activity like a big flare eruption or coronal mass ejections(CMEs). Especially, KOMPSAT-1 as a low earth orbit satellite has a distinct increase of the drag acceleration by the variations of atmospheric friction. We consider factors of solar activity to have serious effects on the satellite drag from two points of view. One is an effect of high energy radiation when the flare occurs in the Sun. This radiation heats and expands the upper atmosphere of the Earth as the number of neutral particles is suddenly increased. The other is an effect of Joule and precipitating particle heating caused by current of plasma and precipitation of particles during geomagnetic storms by CMEs. It also affects the density of neutral particles by heating the upper atmo-sphere. We investigate the satellite drag acceleration associated with the two factors for five events selected based on solar and geomagnetic data from 2001 to 2002. The major results can be summarized as follows. First, the drag acceleration started to increase with solar EUV radiation with the best cross-correlation (r = 0.92) for 1 day delayed F10.7. Second, the drag acceleration and Dst index have similar patterns when the geomagnetic storm is dominant and the drag acceleration abruptly increases during the strong geomagnetic storm. Third, the background variation of the drag accelerations is governed by the solar radiation, while their short term (less than a day) variations is governed by geomagnetic storms.

• Investigative Magnetic Resonance Imaging
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• v.3 no.2
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• pp.173-178
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• 1999

Purpose : To evaluate the usefulness of functional MRI (fMRI) of visual cortex in patients with ischemic infarction in the occipital lobe. Materials and Methods : Four patients with the symptoms and signs of visual cortical ischemia were included. Functional MRI was performed by 2D-FLASH technique with the parameter of 90/56msec TR/TE, $40^{\circ}$ flip angle, $240{\times}240{\;}FOV,{\;}64{\times}128$ matrix number, 8.32 seconds acquisition time, 8mm slice thickness. An axial slice including both visual cortices was selected and alternative activation and resting of the visual cortex was performed using red color photostimulator. all patients undertook visual field test, and vascular abnormality was examined by MRA (n=4) and DSA (n=2). fMRI results were compared with the results of a visual field test, conventional MRI and cerebral angiography. Results : On fMRI, decreased activity of the visual cortex was found in the occipital lobe corresponding to stenosis of the posterior cerebral artery or its branch noted on angiogram. However, 2 of 4 patients showed no abnormal findings on conventional MRI. Visual field defect was noted in 3 patients, one and of whom showed no abnormality on conventional MRI and diffusion-weighted image, but revealed decreased activity in the corresponding visual cortex on fMRI. Conclusion : fMRI may be a sensitive method for detection of the status of decreased blood flow or vascular reserve which other methods can not.

• Journal of the Korean Society for Railway
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• v.11 no.4
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• pp.398-403
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• 2008

The propulsion for locomotive application has changed from the DC motor system to the induction motor system. Although the induction motor system has almost reached the stage of maturity, this system also needs to be changed to the PM motor system for the direct drive without using reduction gear. Thus, the IPMSM (Interior buried Permanent Magnet Synchronous Motor) has been adopted to meet the locomotive driving specification. Where the wheel is directly dirven by the traction motor. In this paper, the investigation on IPMSM satisfying driving specifications for the direct drive has been performed using the advanced FEM.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.1
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• pp.9-15
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• 2007

Purpose: Repetitive transcranial magnetic stimulation (rTMS) has recently been clinically applied in the treatment of drug resistant depressed patients. There are mixed findings about the efficacy of rTMS on depression. Furthermore, the influence of rTMS on the physiology of the brain is not clear. We prospectively evaluated changes of regional cerebral blood flow (rCBF) between pre- and post-rTMS treatment in patients with drug resistant depression. Materials and Methods: Twelve patients with drug-resistant depression (7 male, 5 female; age range: $19{\sim}52$ years; mean age: $29.3{\pm}9.3$ years) were given rTMS on right prefrontal lobe with low frequency (1 Hz) and on left prefrontal lobe with high frequency (20 Hz), with 20-minute-duration each day for 3 weeks. Tc-99m ECD brain perfusion SPECT was obtained before and after rTMS treatment. The changes of cerebral perfusion were analyzed using statistical parametric mapping (SPM; t=3.14, uncorrected p<0.01, voxel=100). Results: Following areas showed significant increase in rCBF after 3 weeks rTMS treatment: the cingulate gyrus, fusiform gyrus of right temporal lobe, precuneus, and left lateral globus pallidus. Significant decrement was noted in: the precental and middle frontal gyrus of right frontal lobe, and fusiform gyrus of left occipital lobe. Conclusion: Low-frequency rTMS on the right prefrontal cortex and high-frequency rTMS on the left prefrontal cortex for 3 weeks as an add-on regimen have increased and decreased rCBF in the specific brain regions in drug-resistant depressed patients. Further analyses correlating clinical characteristics and treatment paradigm with functional imaging data may be helpful in clarifying the pathophysiology of drug-resistant depressed patients.

• Korean Journal of Food Science and Technology
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• v.33 no.5
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• pp.507-513
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• 2001

An effective extraction methods of a garlic were investigated in order to improve the functional properties of the extracts. The solid yield, electron donating ability (EDA), nitrite-scavenging effects (NSE), peroxide value (POV) and total thiosulfinates contents of garlic extracts were determined. In order to improve the functional properties of extracts prepared with several organic solvents and acids, concentration and pH adjustment of the selected solvent and addition of acids and salts to solvents were also examined. Among the solvents tested, the methanol and ethanol extracts were found to be the most effective on the base of functionality and solid yields. The highest EDA, NSE and thiosulfinate value were obtained with 50% ethanol. The pH control of solvent and addition of citric acid, NaCl and phosphates to 50% ethanol did not affect on the functionality of the extracts. Therefore the optimal solvent for the best functional properties of garlic extract was 50% ethanol.

• Journal of the Korean Applied Science and Technology
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• v.37 no.1
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• pp.91-101
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• 2020

The purpose of this study was to investigate the influence of obesity on the expression of autophagy-related proteins in cardiac muscle. To this end, obesity was induced in rats through 20 weeks of high-fat diet, and the animals were then subjected to 8 weeks of treadmill exercise. Subsequently, the expression of proteins that regulate the induction of autophagy, formation of autophagosome, and fusion of autophagosome and lysosome was confirmed. Obesity was induced in the experimental animals (SD rats) through 20 weeks of high-fat diet (carbohydrate: 20%, fat: 60%, and protein: 20%), and they were subsequently subjected to 8 weeks of treadmill exercise (5 days/week, 30 min/day, 5 minutes; 8m/min, 5 minutes; 11m/min, 20 minutes; 14m/min). The experimental groups comprised the normal diet control group (ND-CON, n=10), high-fat diet comparison group (HFD-CON, n=10), and high-fat exercise group (HFD-TE, n=10). Oral glucose tolerance test was conducted before and after 8 weeks of treadmill exercise, and the area under the curve (AUC) was calculated. Through fasting insulin and fasting glucose levels, HOMA-IR, which is an index of insulin resistance, and abdominal visceral fat/body weight (AVF/BW) were calculated for comparison. Moreover, autophagy-related proteins were analyzed from cardiac tissue to investigate the effects of exercise training. Obesity was successfully induced in the HFD-CON group through long-term high-fat diet, and the HFD-CON group had higher body weight, AUC, HOMA-IR, and AVF/BW compared to the ND-CON group. The HFD-TE group, which underwent 8 weeks of treadmill exercise, showed improvements in AUC, HOMA-IR, and AVF/BW. Although the body weight tended to decrease as well, there was no statistically significant difference. mTOR and AMPK, which are involved in the induction of autophagy, both decreased in obesity but increased upon exercise. Beclin-1, BNIP3, ATG-7, p62, and LC3, which are related to the formation of autophagosomes, all increased in obesity and decreased after exercise. Cathepsin L and LAMP2, which regulate the fusion of autophagosome and lysosome, both decreased in obesity and increased upon exercise. Physical activity, including treadmill exercise, was found to induce normal autophagy and improve pathological phenomena observed in metabolic diseases. Therefore, the findings suggest the need to consider treadmill exercise as a primary means to achieve effective prevention and treatment of cardiac diseases.