• Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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• 2003.04a
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• pp.239-246
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• 2003

BPR(Business Process Re-engineering)은 업무 프로세스를 혁신적으로 재설계 함으로써 급속한 외부환경과 내부환경의 변화에 능동적으로 대처하고자 하는 기업의 경영혁신 기법, 조직 재설계의 수단으로 도입되었다. 해마다 시행되고 있는 정보화평가위원회의 국가 정보화 사업에 대한 평가는 정보화 사업의 성과관리에 있어 BPR에 따른 조직과 제도개선 성과를 포함하여 제도혁신에 대한 인센티브 제공 둥 조직과 제도혁신 강화의 필요성이 강하게 주장되는 등 BPR은 공공부문으로 점차 확대 될 추세이다. 본 연구는 조직적 문제의 해결을 통하여 지방자치단체 GIS의 효율성을 제고 하고자 하는 목적으로 출발하였다. 따라서 BPR의 이론적 고찰을 통하여 지자체 GIS BPR의 개념을 정의하고, 지방자치단체의 GIS 시스템 도입 이후의 업무 프로세스의 변화, 업무 변화의 양상, 잠재적 업무 효과를 BPR의 기법을 통해 보여줌으로써 조직 재설계의 수단으로 GIS BPR의 가능성을 모색하였다. 이는 GIS 발달 단계에 따른 효과 창출의 패러다임을 고려한 지방자치단체 GIS 업무의 변화를 수용하는 능동적이고 융통성 있는 조직 모형을 찾는 것이라 할 수 있다. 따라서 단위조직, 진화조직, 전체조직의 GIS 발달 단계에 따른 지방자치단체 GIS 조직 모형을 규정하였다. 본 연구를 통한 시사점은 지방자치단체 GIS 조직이 현재의 단위조직 수준에서 진화조직의 단계를 걸쳐 전체조직으로 향하는 가능성을 제시했다는 점이다. 이는 지방자치단체가 각각의 단계에서 GIS의 도입 효과를 창출하기 위하여 충실히 수행해 할 것이 무엇인지를 BPR을 통해 조직적 차원에서, 그리고 조직이 다루는 업무영역의 차원에서 접근했다는 점에서 그 의의가 있다. 본 연구의 결과를 통해 지방자치단체 GIS 기본계획에 있어 조직 측면의 장기적 비전의 제시가 가능하며 이를 통해 보다 성숙된 GIS 사업의 추진과 효율적인 시스템의 운영이 가능할 것이다.. 이상의 결과를 종합해볼 때, ${\beta}$-glucan은 고용량일 때 직접적으로 또는 $IFN-{\gamma}$ 존재시에는 저용량에서도 복강 큰 포식세로를 활성화시킬 뿐 아니라, 탐식효율도 높임으로써 면역기능을 증진 시키는 것으로 나타났고, 그 효과는 crude ${\beta}$-glucan의 추출조건에 따라 달라지는 것을 알 수 있었다.eveloped. Design concepts and control methods of a new crane will be introduced in this paper.and momentum balance was applied to the fluid field of bundle. while the movement of′ individual material was taken into account. The constitutive model relating the surface force and the deformation of bundle was introduced by considering a representative prodedure that stands for the bundle movement. Then a fundamental equations system could be simplified considering a steady state of the process. On the basis of the simplified model, the simulation was performed and the results could be confirmed by the experiments under various conditions.뢰, 결속 등 다차원의 개념에 대한 심도 깊은 연구와 최근 제기되고 있는 이론의 확대도 필요하다. 마지막으로 신뢰와 결속에 영향을 미치는 요소간의 개념적 분류, 차이의 검증, 영향력 등

• Korean Journal of Social Welfare Studies
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• v.43 no.1
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• pp.5-29
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• 2012

The present study was to explore what makes adolescents think of themselves as troublemakers even without conduct problems. It was expected that the failure to attain socio-developmental milestones(e.g., healthy relationships with others, academic achievement) would lead to form trait aspect of deviant self-concept. A latent state-trait autoregressive modeling was used to analyze five annual waves of data from 3,449 adolescents taken from the Korean Youth Panel Study. We decomposed trait and state aspect of deviant self-concept and identified significant predictors of trait-like deviant self-concept, while additionally testing for gender differences. Our results showed that conduct problems had greater effect on deviant self-concept among girls compared with boys. Conduct problem was most predictive of deviant self-concept, and yet both poor peer-relations and school failures predisposed adolescents to have deviant self-concept. Low academic achievement conferred risk for trait aspects of deviant self-concept with no gender difference, whereas poor peer relation was more predictive among girls. It highlights the cultural value system underlying self-concept and how and why adolescents think of themselves as troublemakers.

• Korean Journal of Social Welfare Studies
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• v.44 no.2
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• pp.169-199
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• 2013

This study has a purpose to analyze trajectories of life satisfaction of the elderly after their retirement and how the characteristics of individual, retirement and family relationship have an effect on the life satisfaction. This study has investigated the Korean elderly, who had been retired, using the data from three waves(1st wave(2005)~3rd wave(2009) of the Korean Retirement and Income Panel(KReIS). Data analysis has been used to identify the predictors of the intercept and slope related to the life satisfaction after retirement, focusing the trajectories of the life satisfaction after retirement and individual characteristics, retirement characteristics and family relationship with application of the growth curve model by Amos 20.0. First, the intercept of the life satisfaction after retirement was somewhat below average. Life satisfaction averagely increased little by little from 1st wave to 3rd wave. Second, by conducting the conditional growth curve model, the study revealed that the intercept of the life satisfaction after retirement is high on individual characteristics(sex, educational level, income, health status) and in retirement characteristics(voluntary retirement) and satisfaction with family relationship and married life). Furthermore, health status, voluntary retirement, and satisfaction with family relationship asserted the meaningful variables in the slope of life satisfaction after retirement.

• The Journal of the Convergence on Culture Technology
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• v.9 no.2
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• pp.57-65
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• 2023

This study examined the obstacles of important factors involved in the start-up decision process for prospective entrepreneurs and plans after graduation while attending hair and beauty colleges and analyzed them in a phenomenological way to establish countermeasures. The subjects of the study agreed to collect data from 10 prospective entrepreneur doctors and plans after graduation while attending hair and beauty college located in G, and were in-depth from December 15 to December 30, 2022. The collected data were analyzed using the Colaizzi method. The results of this study were extracted with 13 topics and two subject collections that represent the characteristics of the experience in the preliminary start-up process of the participants. Based on the results of this study, it is meaningful to examine the obstacles of the factors that are importantly involved in the start-up decision process and establish countermeasures accordingly. In conclusion, at a time when the market for start-ups is expanding and government support is increasing, the factors affecting the will of college students, who are potential professional managers in the future, and effective implications for enhancing the university's start-up infrastructure, start-up difficulties, and start-up motivation were obtained. Therefore, it is urgent to develop efficient performance counseling research or program counseling that can promote and support mental and environmental growth through career development required for the difficulties of the decision process of prospective entrepreneur hair college students and the situations they face. It is necessary to develop various measurement tools in consideration of the level of career development and development of a start-up decision-making process model that can fully grasp the status of start-ups of prospective start-ups.

• Journal of Distribution Science
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• v.10 no.5
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• pp.37-44
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• 2012

In this paper, we investigate several factors that affect the locational decision of discount stores by using previous studies on the marketing area and the location of commercial facilities. We selected 21 primary variables that are expected to influence the decision of store location and, by factor analysis, grouped them into five underlying factors. Among these, the demographic factor, which shows the potential purchasing power level, had the greatest impact on the locational decision for the store. However, we found individual stores positioned according to unique locational characteristics in addition to the demographic factor. It means that we have to additionally consider if the vicinity of the market is based on any physical properties. Many previous studies proposed four decision factors for store location: the economic factor, the demographic factor, the land utilization factor, and traffic factor. However, the fivefold factors-our distinctive contribution-are more concrete and persuasive according to Korean reality. We show that location preference is based on the following criteria: (1) the area is densely populated, (2) houses stand close together, (3) residents have a high income level, (4) road traffic is developed and easy to access, and (5) public transportation is well developed. The demographic factor has the greatest impact on the location of a discount store. The number of households has a greater relevance to the demographic factor than does the individual consumer. Second, discount stores relatively prefer places where houses are located close together because such places offer easy access to the market. Third, a place whose residents have a high income level will be preferred, with its large cars and excellent traffic conditions. Fourth, a location would be highly rated if the roads around commercial facilities are well developed and their accessibility is good. Finally, discount stores must be located close to bus stops because female consumers, including housewives-the most important customers-evaluate stores based on distance. In this research, the variable of consumer attitude and preference was excluded, and the location factors of discount stores were analyzed according to a microscopic view through physical spatial data. In the future, the opening of new discount stores based on the five factors indicated above will require a comparatively shorter time from the first project feasibility analysis. In addition, the result of our study can be applied to the field of public policy for constructing and attracting large-scale distribution facilities.

• Proceedings of the Korean Society of Computer Information Conference
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• 2013.01a
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• pp.149-152
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• 2013

이 연구는 스마트교육환경에서의 교육용 앱을 평가하기 위한 신뢰롭고 타당한 도구를 개발하는데 있다. 기존 선행연구에 기초해서 교육용 앱의 평가를 위한 평가모형을 도출했으며, 이 모형은 4개의 평가영역(교수 학습측면, 화면디자인측면, 기술측면, 경제 윤리측면)과 13개 평가요소들로 구성되었다. 이 잠재모형의 통계적 타당성 검증을 위한 자료수집을 하고자, 경기도 소재 중학교 1곳과 고등학교 2곳의 학생 156명을 대상으로 교육용 앱을 평가하는데 있어서 각 평가문항이 갖는 중요도를 평가하였다. 수집된 자료를 탐색적 요인분석한 결과, 교육용 앱을 평가하는 영역으로 교수 학습(흥미성 자기주도성 실용성, 인지발달성), 화면디자인(디자인의 적합성, 어휘의 정확성), 기술(호환성, 안정성), 경제 윤리(경제성, 윤리성) 등 4개 영역이 제안되었다. 또한 문항내적일관성을 확인하고자 신뢰도 분석한 결과, 각 평가영역 별 Cronbach ${\alpha}$는 .88, .85, .82, .80으로 모두 적합한 수준을 보였다. 따라서, 이 연구를 통해 도출된 교육용 앱 평가도구는 통계적으로나 타당성과 신뢰성 측면에서 의미 있는 것으로 판단할 수 있다.

• Development and Reproduction
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• v.10 no.1
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• pp.55-61
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• 2006

There is growing concern that dietary soy intake is associated with protection of breast cancer. However, questions persist on the potential adverse effects of the main soy constituent genistein(GS) on female reproductive physiology. In this study, we examined whether prepubertal exposure to GS affected on the onset of puberty and the associated reproductive parameters such as hormone receptor expressions in female rats. GS(100mg/kg/day) was administrated daily from postnatal day 25(PND 25) to the day when the first vaginal opening(VO) was observed, and the animals were sacrificed on the day after VO occurred. Gross anatomy and tissue weight were compared to test the GS's effect on the cell proliferation. Furthermore, histological studies were performed to assess the structural alterations in tissues. Specific radioimmunoassay(RIA) were carried out to measure serum LH levels. To determine the transcriptional changes in progesterone receptors(PR), total RNAs were extracted from ovary and uterus and were applied to semi-quantitative reverse transcription polymerase chain reaction(RT-PCR). As a results, advanced VO was shown in the GS group(PND $31.2{\pm}0.6$) compared to the vehicle group (PND $35.3{\pm}0.7$). GS treatment significantly increased wet weight of ovaries and uteri compared to the vehicle group. Increased serum LH levels were also shown in the GS group. Graafian follicles and corpora lutea(CL) were observed only in the ovaries from GS treated animals. Similarly, hypertrophy of luminal and glandular uterine epithelium were found only in the GS group. Collectively, these effects were probably due to the estrogenic effects of GS. In the semi-quantitative RT-PCR studies, the transcriptional activities of PR in both ovary and uterus from GS-treated group were significantly higher than those from the vehicle group. The present studies demonstrated that acute exposure to GS, at levels comparable to the ranges of human exposure, during the critical period of prepubertal stage activates the reproductive system resulting precocious puberty in immature female rats.

• Journal of Korean Home Economics Education Association
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• v.15 no.3
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• pp.1-12
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• 2003

The purpose of this study is to provide basic information for the development of Creative Discretionary Activity Program to Home Economics teachers. The need scales were developed based on the development characteristics of adolescence and data was collected from 521 middle school students in the seoul. The results are as fallows. 1. Among the seven areas self-understanding and career explorations showed the highest degree of demand. and the area of family relationship and friendship and maladjustment of adolescents followed, knowledge about sex and manner awareness took the lowest position. 2. Finding potential ability, understanding aptitude and personality. understanding IQ and EQ, solution of character showed the highest degree of demand. and solution of stress, interest identification. changing society and new career followed. 3. Demands for Creative Discretionary Activity showed significant difference according to socio-demographic variables such sex, family types and economic levels.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.1819-1823
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• 2007

유역에서 상류 유역 또는 수변을 따라 자연 자원을 이용하여 조성되어야 할 완충지대는 비점오염의 영향을 줄이기 위한 중요한 최적 관리공법이다. 교란된 토지 피복과 수변 완충지대를 관리 및 복원할 때 같은 지형조건이라도 식생 종류, 발달정도, 토양조건에 따라 오염물 제거효과가 다를 수 있으며, 최소 완충지대 길이도 제거 오염물질 대상별로 적합하게 설계되고 해석되어야 한다. 본 연구의 목적은 용담댐 유역에서 SWAT 모델을 이용하여 식생 완충지대의 비점오염원 저감 모의 재현성을 평가하는 것이였다. 소유역의 관측값과 모델 예측값에 대한 모델의 검 보정이 선행되었으며 그 중에서 가장 높은 모델 효율을 가지는 소유역에서 three zone concept의 90m 수변완충지대를 지방하천을 경계로 하여 토지 피복도를 변화시켜 SWAT 모델에 적용하였다. 이 때 교목으로는 포플러 (Populus, 30m)을 적용하였고, 포플러의 높이 및 Leaf area index를 조정하여 관목 지대(30m)에 입력하였다. 잔디 지대(30m)는 자연초지를 선택하였다. 또한 지형변수(average slope)와 Manning's coefficient을 수변완충지대의 조건에 고려하여 변화를 주었고 이에 따른 유출량 및 유사량, T-N, T-P의 변화율을 조사하였다. 또한 5, 10, 30m의 식생 여과대를 밭 지역에만 적용하여 오염물의 저감 효율을 평가하였다. SWAT 모델은 각 소유역에서 발생된 전반적인 유출량과 수질변수의 추세를 잘 예측하였으며 정자천 소유역이 선택되었다. 모의된 완충지대에서는 연평균 940 m3/ha의 유출량이 감소되는 것으로 유사농도는 28.7 %의 저감효과를 보였다. 그러나 T-N, T-P의 농도는 오히려 증가되었는데 본 연구에서 고려된 보다 수변완충지대를 조성할 때 지하수 수위, 식생 성장변화 등과 같은 보다 정확한 설계 인자 산출 및 모델 DB 개발이 유역모델에 포함되어야 할 것으로 판단되었다.한 해결책을 얻어내는 상호보완적인 결과를 추구한다. 그가 디자인하는 작품은 전형적인 이미지를 내포하지 않는다. 즉 그의 작품은 기존의 가치와 이념적인 것은 배제하고, 창의적인 개념을 도출하였다.형모서리는 건물 특화 성격이 강하므로 불가피할 경우 소형 액센트 광고 위치를 미리 벽면으로 할애하는 것이 경관 및 입면계획에 유리한 것으로 분석되었다. 불확실도 해석모형 등의 새로운 기능을 추가하여 제시하였다. 모든 입출력자료는 프로젝트 단위별로 운영되어 data의 관리가 손쉽도록 하였으며 결과를 DB에 저장하여 다른 모형에서도 적용할 수 있도록 하였다. 그리고 HyGIS-HMS 및 HyGIS-RAS 모형에서 강우-유출-하도 수리해석-범람해석 등이 일괄되게 하나의 시스템 내에서 구현될 수 있도록 하였다. 따라서 HyGIS와 통합된 수리, 수문모형은 국내 하천 및 유역에 적합한 시스템으로서 향후 HydroInformatics 구현을 염두에 둔 특화된 국내 수자원 분야 소프트웨어의 개발에 기본 토대를 제공할 것으로 판단된다.았다. 또한 저자들의 임상병리학적 연구결과가 다른 문헌에서 보고된 소아 신증후군의 연구결과와 큰 차이를 보이지 않음을 알 수 있었다. 자극에 차이가 있지 않나 추측되며 이에 관한 추후 연구가 요망된다. 총대장통과시간의 단축은 결장 분절 모두에서 줄어들어 나타났으나 좌측결장 통과시간의 감소 및 이로 인한 이 부위의 통과시간 비율의 저하가 가장 주요하였다. 이러한 결과는 차가운 생수 섭취가 주로 결장 근위부를 자극하는 효과를 발휘하는 것이 아닌가 해석된다. 이와 같은 연구결과를 통해 생다시마를 주원료로 개발된 생다시마차와 생다시마 음료가 만성 기능성 변비 증세를 개선하는 효능이 잠재적으로 있음을 확인하였다. 그러나 생약제재의 변비약 수준으로 변비 개선 효능을 증대하기 위해서는 재료 배합비의 개선이나 대장 운동기능을 향상시키는 유효성분의 보강 등이 필요하다는 점도 알 수 있었다.더불어 산화물질 해독에 관

• Journal of Life Science
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• v.32 no.1
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• pp.63-69
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• 2022

The thioredoxin reductase (TrxR) system is essential for cell survival and function by playing a pivotal role in maintaining homeostasis of cellular redox and regulating signal transduction pathways. The TrxR system comprises thioredoxin (Trx), TrxR, and nicotinamide adenine dinucleotide phosphate. Trx reduced by the catalytic reaction of the TrxR enzyme reduces downstream proteins, resulting in protection against oxidative stress and regulation of cell differentiation, growth, and death. Cancer cells survive by improving their intracellular antioxidant capacity to eliminate excessively generated reactive oxygen species (ROS) due to infinite cell proliferation and a high metabolic rate. Therefore, cancer cells have high dependence and sensitivity to antioxidant systems, suggesting that focusing on TrxR, a representative antioxidant system, is a potential strategy for cancer therapy. Several studies have revealed that TrxR is expressed at high levels in various types of cancers, and research on anticancer activity targeting the TrxR system is increasing. In this review, we discuss the feasibility and value of the TrxR system as a strategy for anticancer activity research by examining the relationship between the function of the intracellular TrxR system and the development and progression of cancer, considering the anticancer activity and mechanism of TrxR inhibitors.