• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.11
• /
• pp.189-196
• /
• 2019

This study identifies the moderating effects of cognition on the relationship between self-care confidence and self-care behavior in the diabetic elderly. The participants were 205 elderly subjects with diabetes, who visited a citizen health center located in D city, Korea. Data were collected from 20th April to 31st August 2015, and were analyzed by t-test and multiple regression. Our results reveal no significant differences between the depressive and non-depressive groups, when considering diabetes self-management confidence, knowledge, behavior and cognitive function. Cognitive function had a moderating effect in the relationship between self-care confidence and self-care behavior only in the depressed group. Our results indicate that it is therefore necessary to apply individual nursing intervention based on cognitive function and depression level, and to develop various programs for improving the cognitive function and depression amongst the diabetic elderly.

• Journal of Life Science
• /
• v.32 no.10
• /
• pp.812-820
• /
• 2022

Depression is a psychiatric disorder characterized by depressed mood, anhedonia, fatigue, and altered cognitive function, leading to a decline in daily functioning. In addition, depression is a serious and common mental illness not only in an individual's life but also in society, so it must be actively treated. Autophagy is involved in the pathophysiological mechanism of mental illness. According to a recent study, it is known that autophagy-induced apoptosis affects neuroplasticity and causes depression and that antidepressants regulate autophagy. Autophagy is a catabolic process that degradation and removes unnecessary organelles or proteins through a lysosome. And, it is essential for maintaining cellular homeostasis. Autophagy is activated in stress conditions, and depression is a stress-related disease. Stress causes damage to cellular homeostasis. Recently, although the role of autophagy mechanisms in neurons has been investigated, the autophagy of depression has not been fully studied. This review highlights the new evidence for the involvement of autophagy in the pathophysiological mechanisms and treatment of depression. To highlight the evidence, we present results from clinical and preclinical studies showing that autophagy is associated with depression. Understanding the relevance of autophagy to depression and the limitations of research suggest that autophagy regulation may provide a new direction for antidepressant development.

• Journal of Hospice and Palliative Care
• /
• v.8 no.2
• /
• pp.190-199
• /
• 2005

Purpose: Objectives of this study was to investigate the level of anxiety and depression according to the stages of autologous and allogeneic hematopoietic stem cell transplantation (HSCT). It would be provide the basis for effective psycho-emotional nursing intervention. Methods: We report on 52 patients, including 19 with autologous HSCT, and 33 with allogeneic HSCT from August 2002 to August 2003, at a university hospital. Spielberger's State-Trait Anxiety Inventory and Jung's Depression Inventory were used to measure levels of anxiety and depression, respectively, at admission time, the day before HSCT, and discharge time. Data was analyzed using SAS program that included Chi-square test, Fisher's exact test, repeated measures ANOVA and Stepwise multiple regression analysis. Results: In all stages of HSCT, the level of anxiety of patients who underwent allogeneic HSCT was significantly higher than that of autologous HSCT (P=0.047). The depression at the day before HSCT was significantly higher than that at admission. The major variable affecting anxiety in autologous HSCT was depression. Specially depression and gender were significant predictors to explain anxiety in allogeneic HSCT at admission time (61%). Experience of relapse and gender were significant predictors to explain anxiety in allogeneic HSCT at discharge time (36%). Conclusion: We recommend that the anxiety and depression be researched during the stages of allogeneic HSCT, specifically in the day before HSCT. It is necessary to develop an effective psycho-emotional nursing intervention according to the stages of HSCT.

• 한국노년학
• /
• v.32 no.4
• /
• pp.961-973
• /
• 2012

The aims of this study are to identify levels of diabetes self-care activities and find associated factors of the elderly with Type 2 diabetes. The participants for this study were 264 elderly Koreans over 65 years old who visited one general hospital in S city in South Korea for their medical treatment. In the results, there are few statistically significant differences in general characteristics and disease related variables according with diabetes self-care activities (DSCA). DSCA showed negative correlation with depression (r=-.278, p=.033) and positive correlation with ADLs(r=.310, p=.013)and IADLs(r=.415, p=.001). Therefore, the findings of this study suggest implementing self-care activities to the elderly with diabetes based on their psychological factors (depression) and functional capacities (ADL and IADL). In addition, the advanced research will be needed for developing tailored nursing educations and interventions to improve diabetes self-care activities of elderly patients.

• The Journal of the Korea Contents Association
• /
• v.13 no.3
• /
• pp.211-217
• /
• 2013

A body dysmorphic disorder refers to a state that individuals whose external appearance is normal consider their appearance to be meta-morphosed, or think there's something wrong with it, or view a trifle deficiency as severely disfigured. The purpose of this study was to examine the body dysmorphic disorder and depression of health-related and health-unrelated majors in an effort to compare the two groups. And it's also meant to investigate the relationship between body dysmorphic disorder and depression. The subjects in this study were 400 students at K college located in Gangwon Province. Out of them, the major of the 200 students belonged to the health science track, and that of the 200 students didn't. After a self-administered survey was conducted, the answer sheets from 319 respondents were analyzed. As a result, there appeared no differences between the health-related majors and the health-unrelated majors in body dysmorphic disorder. Although there might be various factors to concern body dysmorphic disorder, both groups found themselves to suffer from more depression when they had a severer body dysmorphic disorder, and their body dysmorphic disorder exerted a statistically significant influence on their self-rated depression. Therefore the careful management of body dysmorphic disorder was required, and it's especially needed to make research in that of health-related majors. At the same time, more detailed clinical research efforts should be directed into body dysmorphic disorder and self-rated depression.

• Journal of the Korea Convergence Society
• /
• v.12 no.3
• /
• pp.27-34
• /
• 2021

This study aims to provide basic data to identify the effects of oral health behavior and autologous oral health symptoms on factors that affect quality of life of COVID-19 (coronavirus disease 19) depression. This study collected data from July 2020 to September 2020, the research method was finally analyzed for 89 people in the group of depression non-increase and 86 people in the group of depression due to COVID-19. As an analysis method, oral health behavior, autologous oral health symptom and quality of life were compared, and the hierarchical regression analysis was implemented to check the effect of depression on the quality of life. As a result, the effects of depression (��=-0.155, p=0.012) and autologous oral health symptoms (��=0.524, p<0.001) were significant as a result of controlling demographic characteristics and checking the effects on quality of life. Therefore, it is urgent to develop programs related to the mental health of the community to relieve depression and anxiety with COVID-19, and public relations activities will be needed to relieve anxiety about dental visits so that dental treatment can be received at an appropriate time.

• Journal of agricultural medicine and community health
• /
• v.37 no.4
• /
• pp.246-257
• /
• 2012

Objectives: To compare the self-rated health in chronic disease patients with depression, chronic disease patients, and depression patients, and to observe the related factors to the self-rated health of people age 65 and older. Methods: The subjects were 2,549 elderly people, over 65 years old in Busan Metropolitan City who participated in 2009 community health survey. Association between self-rated health and general characteristics, life style and disease status were observed. Depressive symptoms were measured using the Centre for Epidemiologic Studies Depression Scale (CES-D). Analysis of complex sample was done with SAS (ver. 9.2), using ${\chi}^2$-test and multiple logistic regression. Results: Among total 2,549, there were 740 normal people (29.8%), 50 people with depression (1.8%), 1,495 people with other chronic diseases (58.2%), and 264 people with the comobidity of depression and other chronic diseases (10.1%). Good self-related health accounted for 20.3% for the whole, 33.4% for normal, 16.7% for chronic disease, 16.1% for depression, and 3.2% for chronic diseases with depression. Disease, gender, education, income, alcohol drinking, regular exercise and regular walking were independent factors associated with the good self-related health. Conclusions: It is suggested that when the chronic disease control program for the elderly is developed, depression care should be considered along with the program. This program should be given priority to the women and the vulnerable classes and should also be related to the regular walking.

• Journal of Hospice and Palliative Care
• /
• v.8 no.1
• /
• pp.18-29
• /
• 2005

Purpose: Aroma therapy is one modality of alternative medicine. It was well known to have an analgesic, antidepressive and anxiolytic effects. This study is designed to investigate the effect of aroma self hand massage on vital signs, pain, depression, anxiety and stress in breast cancer patients. Methods: 32 female patient over 20 years old were divided into two groups by a non-blinded randomized controlled method. Patient in the aroma group (n=15) massaged their hands twice a day using aroma oil by themselves in their home for 2 weeks. However, those in control group (n=17) had not received my intervention during the study periods. Pain intensity, state anxiety, depression and stress of subjects were evaluated three times (0, 1, 3 weeks) using Visual Analogue Scale (VAS, $0{\sim}10cm$), State Trait Anxiety Inventory (STAI), Beck Depression Inventory Scales (BDIS), Brief Encounter Psychosocial Instrument (BEPSI revised edition). Also the change of patients' accompanying symptoms after aroma massage were analyzed using a structured questionnaire. Results: Pain Intensity decreased in the aroma group compared with control group (VAS changes $-0.83{\pm}1.01\;vs\;0.38{\pm}0.86$, P=0.005). The numbers of accompanying symptoms (P=0.044), depression score (P=0.001) and anxiety score (P=0.008) were significantly decreased in the aroma group, while in control group they increased after 2 weeks. However, the stress score showed no significant changes in both groups ($0.05{\pm}0.85\;vs\;0.04{\pm}0.20$, P=0.1519). The depression, anxiety and stress score showed negative correlation with compliance of aroma massage, but statistically no significant. The systolic blood pressure was a little increased in aroma group ($4.53{\pm}14.43\;vs\;0.0{\pm}7.22$, P=0.026), but was not significant clinically. Patients in the aroma group complained of several symptoms such as headache (20%), paresthesia (6.75%) and nausea (6.7%). However, there were no drop-out patients for those side effects. Conclusion: Aroma self massage during two weeks in breast cancer patients alleviates the pain intensity, depression and anxiety significantly.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.21 no.2
• /
• pp.94-102
• /
• 2020

This study conducted a meta-analysis of the effects of self-management intervention for reducing the depression and anxiety of osteoarthritis patients. The research sources were PubMed, EMBASE, CINAHL, Ovid-MEDLINE and Korean databases from the Korean and foreign literature published until September 30, 2019. The R version 3.5.1 program was used to identify the effectiveness of self-management intervention. As a result, 11 studies from a total of 1,877 articles in the relevant literature were analyzed, and the total number of participants was 2,751. The results showed that the overall effect size for reducing depression and anxiety was -0.44 (95% CI: -0.66, -0.22) in osteoarthritis patients (p <.001). On the sub-analysis, depression was -0.37 (95% CI: -0.66, -0.08), and anxiety was -0.56 (95% CI: -0.92, -0.20). To explain the heterogeneity, the meta-ANOVA was the setting, duration, and provider of intervention. Analysis of the publication bias was performed by a Funnel plot, which was visually relatively symmetrical and was not asymmetric according to Egger's Regression test (bias=0.19, p=.928). The results of this study established clinical evidence by identifying the effects of self-management intervention for reducing the depression and anxiety of osteoarthritis patients.

• Proceedings of the Korea Contents Association Conference
• /
• 2016.05a
• /
• pp.379-380
• /
• 2016

본 연구는 빠르게 진행되고 있는 노인 인구의 증가에 따라 노인들의 사회적, 경제적, 건강상의 복잡한 문제로 발생되는 정신병 문제가 대두되고 있고. 그중 우울증은 노인들의 자살로 이끄는 중대한 질병이므로 본 연구에서는 간단한 자가 치료가 가능한 귀자극 요법을 활용하여 노인들의 우울증에 대한 치료 효과를 알아보고 이에 대한 활용 방법을 제시하고 한다.