• Journal of Applied Biological Chemistry
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• v.53 no.2
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• pp.99-104
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• 2010

The influences on antioxidant activities of the substituents ($R_1-R_4$) on benzo ring in 4-Methyl-2H-benzopyran-2-one analogues (1-23) were discussed quantitatively using three dimensional quantitative structure-activity relationships (3D-QSARs: Comparative molecular field analyses (CoMFA) and Comparative molecular similarity indice analyses (CoMSIA)) methods. The statistical qualities of CoMSIA models were better than those of CoMFA models and the CoMSIA 2 model was optimized model ($q^2$=0.700 & $r^2$=0.979). Also, the contribution ratios (%) of the optimized CoMSIA 2 model were H-bond donor field 43.5%, electrostatic field 41.8% and steric field 14.7% so that the antioxidant activity exhibited a strong correlation with H-bond donor and electrostatic factor of molecules. From the analytical results of the CoMSIA contour maps, if the positive charge favor group and H-bond donor disfavor group were placed in the $R_1-R_4$ positions on the benzo ring, it was predicted that the groups would raised the antioxidant activity.

• The Korean Journal of Pesticide Science
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• v.12 no.1
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• pp.18-23
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• 2008

3D-QSAR on the inhibitory activities of 6-bromobenzo-[4,5]imidazo[$1,2{\alpha}$]-pyridin-8,9-diones analogues as substrate molecule were studied quantitatively using CoMFA and CoMSIA methods. The statistical values of CoMFA model was better predictability and fitness than CoMSIA model. The inhibitory activities according to the optimized CoMFA 2 model were dependent on the steric field (90.4%). From the CoMFA contour maps, it is found that the branched side chain as R-group will be directly attached to the carbon atom (ipso carbon) of substituent, the inhibitory activities had expected to increase. The positive charge favor groups were placed in the position between imidazol ring and pyridine ring, the inhibitory activities would increase. And if the groups of liner type will be substituted, hydrophilic favor group would raise inhibitory activities.

• Journal of Broadcast Engineering
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• v.25 no.4
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• pp.487-496
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• 2020

For the purpose of next generation technology for robot perfomances, a RAoRA (Robot Actor on Robot Arm) structure was proposed using a robot arm joined with a humanoid robot actor. Mechanical analysis, machine design and fabrication were performed for motions combined with the robot arm and the humanoid robot actor. Kinematical analysis for 3D model, spline interpolation of positions, motion control algorithm and control devices were developed for movements of the robot actor. Preliminary visualization, simulation tools and integrated operation of consoles were constructed for the non-professionals to produce intuitive and safe contents. Air walk was applied to test the developed platform. The air walk is a natural walk close to a floor or slow ascension to the air. The RAoRA also executed a performance with 5 minute-running time. Finally, the proposed platform of robot performance presented intensive and live motions which was impossible in conventional robot performances.

• Tunnel and Underground Space
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• v.24 no.4
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• pp.255-274
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• 2014

The target of this study is large scale rock slope collapsed by around 7 pm on August, 2012, which is located at ${\bigcirc}{\bigcirc}$ limestone quarries of Gangneung city, Gangwondo. The slope prior to the collapse is formed as the height of about 200 m and the average inclination of $45^{\circ}$. The estimated amount of the collapse is about $1,500,000m^3$ with respect to the slope after the collapse. Geotechnical and field investigations such as boring, geophysical prospecting, surface geological survey, geological lineaments, borehole imaging, metric 3D imaging, experimental and field test, mining work by year, and daily rainfall were performed to find the cause of rock slope failure. Various analyzes using slope mass rating, stereonet projection, limit equilibrium method, continuum and non-continuum model were conducted to check of the stability of the slope. It is expected that the cause of slope failure from the results of various analysis and survey is due to the combined factors such as topography, rainfall, rock type and quality, discontinuities, geo-structural characteristics as the limestone cavity and fault zones, but the failure of slope in case of the analysis without the limestone cavity is not occurred. Safe factor of 0.66 was obtained from continuum analysis of the slope considering the limestone cavity, so the ultimate causes of slope failure is considered to be due to the influence of limestone cavity developed along fault zone.

• Applied Chemistry for Engineering
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• v.1 no.2
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• pp.190-196
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• 1990

The biological active monomer, 1-(methacryloyloxymethyl)-5-fluorouracil(MAOMFU) was synthesized from 2, 4-bis(trimethylsilyloxy)-5-fluoropyrimidine. Poly(MAOMFU) poly(1-methacryloyloxymethyl-5-f1uorouracil-co-methyl methacrylate), and poly(MAOMFU-co-MMA) were also obtained by radical polymerization at $60^{\circ}C$. The monomer reactivity ratios, $r_1$ and $r_2$ were determined by $Kelen-T\ddot{u}d\ddot{o}s$ method ; $r_1(MAOMFU)=0.72$, and $r_2(MMA)=1.24$. These reactivity values imply that the copolymerization was mainly affected by the steric hindrance of MAOMFU. It was found from kinetic measurements that the rate constants of solvolysis are given as $6.42{\times}10^{-5}sec^{-1}$ and $7.40{\times}10^{-6}sec^{-6}$, respectively, for MAOMFU and poly(MAOMFU).

• Journal of Korean Society for Geospatial Information Science
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• v.12 no.4 s.31
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• pp.27-33
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• 2004

Recently, as a part of NGIS project, cultural-assets digital map is produced by cultural properties administration and local autonomous entities. Cultural-assets unified GIS(Geographic Information System) is essential to cultural properties managers md other organizations which are executing land related business for appling it at planning stage. With explosive national land developments, it has been obligated to implement surface survey by the cultural properties protection Art. In this paper, the authors used the district of Sachon city and made 3D terrain model using digital map which is made of 1/5000 stale. Moreover, the authors improved to RDBMS(Relational Database Management System) structure and remodeled the existing DB design in detail, and also tried recovery of past sea level, based on researches about the water level of southern area. By recover past sea level. the shell mound, apart from lever is actually near lever at past, and it make sure its nature. The authors suggested to realize shape and kind of remains which have 3D information of accuracy and actualization from surface-surveying to excavation.

• The Journal of Korean Academy of Prosthodontics
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• v.50 no.2
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• pp.85-91
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• 2012

Purpose: The object of this study was to determine if the low-priced alloy and metal UCLA abutment could be available for manufacturing bar-retained framework of implant prosthesis. Materials and methods: Bar structure was classified into 4 groups, The specimen of group 1 and 2 were based on casting high noble metal alloys and noble metal alloys with gold UCLA abutment. The specimen of group 3 and 4 were based on casting noble metal alloys and base metal alloys with metal UCLA abutment. Cast bar structure was installed in an acrylic resin model and only the screw on the hexed abutment side was tightened to 20 Ncm. On the opposite side, vertical discrepancy was measured with stereo microscope from front, back, and lateral side of the implant-abutment interface. One-way ANOVA was performed to analyze the marginal fit discrepancy. Results: One-way ANOVA test showed significant differences among all groups ($P$<.05) except for Group 1 and 3. Among them, difference between Group 1 and 2 was noticeable. Measured vertical discrepancies were all below $70{\mu}m$ except to Group 2. Conclusion: Base metal alloy and metal UCLA abutment could be used as an alternative to high-priced gold alloy for implant bar-retained framework.

• Journal of The Korean Association For Science Education
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• v.35 no.5
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• pp.919-929
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• 2015

This study aims to develop a modeling-based learning program about geologic structures and to reveal the relationship between the argumentation patterns and levels of students' mental models. Participants included 126 second grade high school students in four sessions of modeling-based learning regarding continental drift, oceanic ridges, transform faults, and characteristics of faults. A modeling-based learning program was implemented in two classes of the experimental group, and teacher-centered traditional classes were carried out for the other students in the comparison group. Science achievement scores and the distribution of students' mental models in experimental and comparison groups were quantitatively compared. The video-taped transcripts of five teams' argumentation were qualitatively analyzed based on the analytic framework developed in the study. The analytic framework for coding students' argumentation in the modeling-based learning was composed of five components of TAP and the corresponding components containing alternative concepts. The results suggest that the frequencies of causal two-dimensional model and cubic model were high in the experimental group, while the frequencies of simple two-dimensional model and simple cross sectional model were high in the comparison group. The higher the frequency of claims, an argumentation pattern was proven successful, and the level of mental model was higher. After the rebuttal was suggested, students observed the model again and claimed again according to new data. Therefore, the model could be confirmed as having a positive impact on students' argumentation process.

• Journal of Digital Convergence
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• v.12 no.3
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• pp.277-288
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• 2014

The purpose of the study is to investigate the students' learning motive through the application of the learner-centered program Creative Teaching Technique(CTT) conducted by undergraduate school of Medical Record Information Management(MRIM), and to improve learning from the results. A questionnaire survey was carried out that started March to June 2013 among the sixty freshmen college students from the Health Administration Department who participated in the CTT during the 12 weeks training. The main results are as follows. The subjects' cognitive results form CTT were relativiely higher in 'increased voluntary participation(4.03)', 'improved concentration(4.00)', 'increased understanding(3.97)' in order. The effects of the tools used in CTT were higher as well in 'two members in a tem(4.08)', 'three-dimensional tools(4.03)' and 'quiz cards(3.95)' in order. While undergoing CTT, the learners considered reviewing repeatedly the content before starting and finishing as mostly helpful. Concludingly, this learner-centered CTT program identified having positive effects on their participation, concentration and understanding. To maximize the learning effects, development and activating a systematic, continuous and supportive program like this CTT is highly recommended.

• Journal of the Korean Chemical Society
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• v.53 no.3
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• pp.302-307
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• 2009

Investigation was conducted to examine whether photochemical reaction of N-(tributylstannyl)- methylphthalimide generates an azomethine ylide intermediate in its excited state as its silyl derivative N-(trimethylsilyl)methylphthalimide which has been observed to form an azomethine ylide. The irradiation of N-(tributylstannyl)methylphthalimide in $D_2O-CH_3$CN generates mono-deuterated N-methylphthalimide as an exclusive product which supports the efficient generation of azomethine ylide intermediate and its trapping by water molecule through a proto-destannylation pathway. However the generated tributylstannyl subsitiuted ylide was not observed to be trapped with a dipolarophile such as methyl acrylate and acrylonitrile present in the reactions which is in contrast with the ylide from N-(trimethylsilyl)methylphthalimide.