• Title/Summary/Keyword: 임상적 연관성

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Brain wave results in children with attention deficit hyperactivity disorder and treatment result with central nervous system stimulants (주의력결핍 과잉행동장애 환아에서 시행한 뇌파 결과 및 중추신경자극제 치료에 따른 결과)

  • Lim, Young Su;Sim, Ji Yun;Son, Jung-Woo;Kim, Won Seop
    • Clinical and Experimental Pediatrics
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    • v.51 no.12
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    • pp.1324-1328
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    • 2008
  • Purpose : Attention deficit hyperactivity disorder (ADHD) is a syndrome characterized by inattention, impulsive disruptive behavior, impaired concentration, and motor restlessness. This study examined the relationships among electroencephalographic (EEG) findings, stimulant use, and seizure occurrence in children with ADHD. Methods : We retrospectively studied 308 children with ADHD who visited the neuropsychiatric clinic of our hospital from January 2001 to December 2005. We retrospectively analyzed age distribution, etiology, abnormal EEG findings, and use of CNS stimulants. Among these children, brain waves was recorded in 84 patients. Results : Eighty-four children (72 males, 85.7%, 9.3 years mean age; 12 females, 14.3%, 8.0 years mean age) with ADHD had electroencephalograms (EEGs) performed at our institute. Nineteen patients (22.6%) demonstrated epileptiform abnormalities, and 65 (77.4%) demonstrated normal EEGs. Stimulant therapy was applied to 59 of 84 patients (70.2%). Seizures occurred in 1 of 65 patients with a normal EEG (incidence, 1.5%) and 3 of 19 treated patients with epileptiform EEGs (incidence, 15.7%). Conclusion : These data suggest that patients with normal EEGs have minor risk for seizure. In contrast, patients with epileptiform EEGs have higher risk for seizure than patients with normal EEGs.

The Relationships Between Mycoplasmic Pneumonia and Production Traits in Pigs (돼지의 마이코플라즈마성 폐렴과 경제형질간의 상관관계 연구)

  • Yoo, Im-Jong;Oh, Hyung-Gil;Park, Byung-Suk;Lee, Ha-Bok;Lee, Jong-Gwan;Jeon, Byung-Kook;Kim, Na-Rae;Lee, Jun-Heon
    • Journal of Animal Science and Technology
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    • v.50 no.4
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    • pp.437-444
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    • 2008
  • Pneumonia is one of the important diseases in commercial pig. In order to delineate the relationships with pneumonia and productions traits, five different economic traits including carcass weight(CW), backfat thickness(BF), meat quality(MQ), carcass characteristics(CC) and pork belly thickness(PB) were measured in 6,362 commercial pigs. Significant differences were observed in all the traits with pneumonia(P<0.01). Carcass weight and backfat thickness decreased significantly as the symptom of pneumonia was severed (P<0.01). Also, when the pneumonia was severed, the carcass characteristics and meat quality became worse compared with normal unaffected animals(P<0.01). In case of pork belly thickness, the significant decrease was observed in pneumonia infected animals compared with normal animals(P<0.01). Based on this study, the pneumonia infection affects most of the important economic traits in pigs and it is ultimately needed to pay more attention to prevent this disease.

Incidental Breast Lesions on Chest CT: Clinical Significance and Differential Features Requiring Referral (흉부 전산화단층촬영에서 우연히 발견된 유방 병변: 임상적 중요성 및 진료 의뢰가 필요한 특징적 영상 소견)

  • Choi, Yun Jung;Kim, Tae Hoon;Cha, Yoon Jin;Son, Eun Ju;Gweon, Hye Mi;Park, Chul Hwan
    • Journal of the Korean Society of Radiology
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    • v.79 no.6
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    • pp.303-310
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    • 2018
  • Purpose: To evaluate the CT features of incidental breast lesions on chest CT and to suggest useful criteria for referral to a specialized breast unit. Materials and Methods: Between May 2009 and April 2014, enhanced chest CT examination reports containing the key word 'breast' were reviewed retrospectively. Patients who had incidental breast lesion and were referred to a specialized breast unit and then underwent pathological confirmation or follow-up over a 1-year period were included. Finally, 86 patients (all female, mean age, $48.9{\pm}12.6years$) were enrolled. Two radiologists evaluated lesion characteristics, including size, shape, margins, and enhancement. The correlations between the CT features and pathologies were evaluated, and the diagnostic accuracy of CT features in various combinations was assessed. Results: Among the CT features, irregular shape, non-circumscribed margin, and high contrast enhancement were different between malignant and benign lesions (p < 0.05). The combination of non-circumscribed margin and high contrast enhancement had the highest accuracy (97.7%). Conclusion: Reliable CT features for incidental malignant breast masses are irregular shape, non-circumscribed margin, and high contrast enhancement. The combination of non-circumscribed margin and high contrast enhancement could help distinguish incidental malignant breast lesions and indicate referral to a specialized breast unit.

The Characteristics of Imipenem-Resistant Bacteria Isolated from One Patient (한 환자에게서 분리된 Imipenem 내성세균들의 특성)

  • Park, Chul;Lee, Hyeok-Jae;Seo, Min-Young
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.413-419
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    • 2017
  • Four imipenem-resistant bacteria were isolated from the clinical specimens of a patient with pneumonia. To identify the isolates, we used the GN card of Vitek II system and performed a phylogenetic analysis based on 16S rRNA gene sequence. The isolates were identified as P. aeruginosa (2 strains), P. monteilii (1 strain), and P. putida (1 strain), and were tested for antibiotic resistance after determining the MIC of imipenem to be $${\geq_-}8{\mu}g/mL$$ using the AST-N225 card of Vitek II system. The imipenem-resistant genotypes were determined using PCR products amplified using specific ${\beta}-Lactamase$ gene primers. The MBL gene was identified in all four isolates. One strain of P. aeruginosa exhibited the VIM and SHV-1 type genes, while the other strain exhibited both VIM and OXA group II genes. According to the antimicrobial susceptibility test, the bacteria were more susceptible to amikacin than other antibiotics. DNA fingerprint analysis using ERIC-PCR to analyze the epidemiological relationship between strains estimated that both the P. aeruginosa isolates were similar, but exhibited different DNA band types. It is uncommon to find four strains of imipenem-resistant bacteria with different DNA band types in a single patient.

Outbreak of Acinetobacter septicemia in a neonatal intensive care unit (신생아 집중치료실에서 집단 발생한 Acinetobacter septicemia)

  • Kim, Myo Jing;Lee, Hye Jin;Son, Sang Hee;Huh, Jae Won
    • Clinical and Experimental Pediatrics
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    • v.49 no.5
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    • pp.494-499
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    • 2006
  • Purpose : Acinetobacter baumannii is increasingly recognized as an important cause of nosocomial infection, especially in neonatal intensive care units. But little is known about the clinical significance and hospital epidemiology of Acinetobacter species other than A. baumannii. The objective of this study is to describe the clinical characteristics and epidemiology of septicemia due to Acinetobacter species other than A. baumannii. Methods : We retrospectively reviewed 11 cases of blood culture proven nosocomial infection which occured in our neonatal intensive care unit from $4^{th}$ to $24^{th}$, February, 2004. To establish epidemiological analysis, we performed environmental cultures and an antibiogram was obtained from susceptability tests of isolated Acinetobacter species. Results : Clinical manifestations including fever, poor feeding, abdominal distension, diarrhea, bloody stool passage, vomiting, tachypnea and apnea were similar to other infectious diseases. Benign clinical courses were compared with poor prognose, including a high mortality rate in septicemia due to A. baumannii. The major predisposing factor among our patients was the presence of a peripheral intravascular catheter. Antibiogram was similar, but surveillance cultures of environmental specimens failed to identify the source of infection. Conclusion : Acinetobacter species other than A. baumannii were often considered relatively avirulent bacteria, but could be pathologic organisms if cultured in patients with clinical symptoms.

Surgical Treatment of Multiple Rice Bodies in Chronic Subacromial and Subdeltoid Bursitis: A Case Report (만성 견봉하 및 삼각근하 점액낭염에 발생한 다발성 쌀소체의 수술적 치료: 증례 보고)

  • Kim, Do-Young;Hwang, Jung-Taek;Lee, Sang-Soo;Seo, Eun-Min;Jo, Yoon-Geol
    • The Journal of the Korean bone and joint tumor society
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    • v.19 no.2
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    • pp.69-73
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    • 2013
  • Multiple rice body formation is a complication of chronic bursitis frequently associated with seronegative rheumatoid arthritis or tuberculosis. It resembles synovial chondromatosis on imaging and clinically. We report on a pathologically diagnosed multiple rice body formation in subacromial and subdeltoid bursitis in a 44-year-old man who was treated by surgical removal and bursectomy. At 16 months after the removal, range of motion of affected shoulder was normal. No evidence of recurrence of rice body in plain X-ray and ultrasonography. Multiple rice body formed in chronic subacromial and subdeltoid bursitis could be treated with surgical removal and bursectomy successfully.

THE STUDY ON THE RELATIONSHIP BETWEEN THE MENARCHE AND THE BONE MATURITY OF MALOCCUSION GROUP (초경시기와 골성숙도의 연관성에 관한 연구)

  • Chang, Youn-Hee;Chung, Kyu-Rhim
    • The korean journal of orthodontics
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    • v.25 no.4
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    • pp.415-423
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    • 1995
  • In order to investigate the relationship between the menarche and the bone maturity of growing girls, the author interviewed about the date of menarche of 70 girls and assessed their bone maturity by hand-wrist radiographs. The results and conclusion were as iollows ; 1. The mean menarcheal age was $12.04{\pm}0.82$ year. 2. There was significant correlation between the time interval after menarche and the ossification stage. 3. The skeletal maturation level at menarche was stage SMI 7 and SMI 8. 4. There was statistically different among the time intervals after menarche according to the ossification stage. 5. The epiphyseal union of radius began about 2 years after menarche. According to this study, the probability of clinical use can be accepted in some range. In another words, skeletal age can be predicted by just interviewing the date and time interval of menarche without hand-wrist radiograph, also, with this information, the level of maxillofacial growth can be assessed.

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FDG-PET/CT Complements Bone Scan with Respect to the Detection of Skip Metastasis of Osteosarcoma: A Case Report (골육종의 도약전이 진단에서 골스캔의 보완검사로서의 FDG-PET/CT: 증례 보고)

  • Cheon, Gi-Jeong;Choe, Jae-Gol;Chae, In-Jung;Lee, Dae-Hee;Song, Sang-Heon;Kim, Myo-Jong;Park, Jong-Hoon
    • The Journal of the Korean bone and joint tumor society
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    • v.18 no.1
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    • pp.45-49
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    • 2012
  • Skip lesion is not uncommon feature in osteosarcoma and considered to be importantly associated with poor prognosis factor, and thus, should be excised with the main mass. The accurate pre-operative evaluation of the intramedullary extent of osteosarcoma is essential, because it determines the level of bone resection. Among the reliable detection methods, bone scan has a drawback of high rate of false negative results and regional MRI has a difficulty to cover the whole involved lesions without clinical suspicion. The authors report a case of osteosarcoma of the distal femur with a proximal skip lesion that was not detected by either regional MR imaging or by bone scan, but which was visualized by FDG-PET/CT.

Music Choices of GIM(Guided Imagery and Music) Therapist in GIM: Narrative Literature Review (GIM(Guided Imagery and Music)에서 GIM 치료사의 음악 선택에 관한 내러티브 문헌 고찰)

  • Kim, Young Shil
    • Journal of Music and Human Behavior
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    • v.11 no.1
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    • pp.39-62
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    • 2014
  • The purpose of this research was to review the music choices of GIM therapists in GIM. Seven databases and nine music therapy journals were searched with keywords such as "Guided Imagery and Music", "GIM", "Helen Bonny", "Bonny method", "Music and Imagery" and "BMGIM" between 1964 to 2013. Every abstract was confirmed to see whether it meets this research topic. 12 of 126 articles that described the reasons for music choices were selected. It is the result of narrative literature review that GIM therapists chose music to match clients' qualities of moods, emotions, feelings related with issues and clients' themes in therapy. In 5 articles among the 12 articles, authors chose music with considering music elements analytically to match clients' states. Reasonable explanations for music choice were reviewed in these 5 articles. There were limitations to obtain common facts between articles because most of 126 articles were case studies which described from therapists's point of view in a qualitative way. A more fundamental research is required to obtain rationales of music choices in GIM as a music-centered music psychotherapy for the further research.

MDM2, p53 and pRb Expression Prior to Definitive Chemoradiotherapy in Esophageal Carcinoma (식도암에서 MDM2, p53, pRb 발현과 동시적 항암화학방사선요법의 결과)

  • Yoon, Mee-Sun;Lee, Jae-Hyuk;Cho, Sang-Hee;Song, Ju-Young;Ahn, Sung-Ja;Chung, Ik-Joo;Chung, Woong-Ki;Nah, Byung-Sik;Nam, Taek-Keun
    • Radiation Oncology Journal
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    • v.25 no.4
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    • pp.193-200
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    • 2007
  • Purpose: This study evaluated the pretreatment expression patterns of MDM2, p53, and pRb proteins to determine if the expression patterns could predict the outcome of concurrent chemoradiotherapy (CCRT) for esophageal squamous cell carcinoma and aid in the decisions for the selection of treatment modalities. Materials and Methods: Fifty-one patients that were treated with definitive chemoradiotherapy for stage $I{\sim}IVa$ esophageal squamous cell carcinoma were selected for this study. Radiotherapy was administered with daily $1.8{\sim}2\;Gy$ fractions up to a median dose of 54 Gy for primary tumors, and with four cycles of cisplatin/5-fluorouracil chemotherapy that was administered every 4 weeks, the first two cycles of which were administered concurrently with radiotherapy. Expression of MDM2, p53, and pRb was investigated by immunohistochemical analysis using pretreatment biopsy specimens. Results: MDM2, p53, and pRb were detected with high immunoreactivity in 19.6%, 27.5%, and 66.7% of the patients, respectively. However, there was no significant correlation between expression of these factors and clinical outcome. By the use of multivariate analysis with nine covariates-age, tumor location, tumor length, stage, pathological response, clinical response, MDM2 expression, p53 expression, and pRb expression, only pathological response and stage were significant factors for cause-specific survival. Conclusion: Expression of MDM2, p53, and pRb was not found to be clinically significant for predicting outcomes after CCRT in this study. Further studies with a larger patient population and longer follow-up periods are needed to re-evaluate the expression pattern and to identify new predictors for CCRT response.