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http://dx.doi.org/10.3345/kjp.2008.51.12.1324

Brain wave results in children with attention deficit hyperactivity disorder and treatment result with central nervous system stimulants  

Lim, Young Su (Department of Pediatrics, College of Medicine and Medical Research Institute, Chungbuk National University)
Sim, Ji Yun (Department of Pediatrics, College of Medicine and Medical Research Institute, Chungbuk National University)
Son, Jung-Woo (Department of Neuropsychiatry, College of Medicine and Medical Research Institute, Chungbuk National University)
Kim, Won Seop (Department of Pediatrics, College of Medicine and Medical Research Institute, Chungbuk National University)
Publication Information
Clinical and Experimental Pediatrics / v.51, no.12, 2008 , pp. 1324-1328 More about this Journal
Abstract
Purpose : Attention deficit hyperactivity disorder (ADHD) is a syndrome characterized by inattention, impulsive disruptive behavior, impaired concentration, and motor restlessness. This study examined the relationships among electroencephalographic (EEG) findings, stimulant use, and seizure occurrence in children with ADHD. Methods : We retrospectively studied 308 children with ADHD who visited the neuropsychiatric clinic of our hospital from January 2001 to December 2005. We retrospectively analyzed age distribution, etiology, abnormal EEG findings, and use of CNS stimulants. Among these children, brain waves was recorded in 84 patients. Results : Eighty-four children (72 males, 85.7%, 9.3 years mean age; 12 females, 14.3%, 8.0 years mean age) with ADHD had electroencephalograms (EEGs) performed at our institute. Nineteen patients (22.6%) demonstrated epileptiform abnormalities, and 65 (77.4%) demonstrated normal EEGs. Stimulant therapy was applied to 59 of 84 patients (70.2%). Seizures occurred in 1 of 65 patients with a normal EEG (incidence, 1.5%) and 3 of 19 treated patients with epileptiform EEGs (incidence, 15.7%). Conclusion : These data suggest that patients with normal EEGs have minor risk for seizure. In contrast, patients with epileptiform EEGs have higher risk for seizure than patients with normal EEGs.
Keywords
Attention deficit hyperactivity disorder; Electroencephalography; Seizure; Methylphenidate;
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