• Title/Summary/Keyword: 임상사용

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Development of Clinical Trial Guidelines for Using Korean Herbal Medicine in Treatment of Common Cold (감기 치료를 위한 한약제제 임상시험 가이드라인 개발)

  • Jiwon Park;Kwan-Il Kim
    • Journal of Society of Preventive Korean Medicine
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    • v.28 no.1
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    • pp.131-157
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    • 2024
  • 목적 : 본 연구는 감기에 대한 한약제제 임상시험을 수행하고 평가하는 데 보편적인 원칙을 제공하는 가이드라인 개발과정 및 내용을 소개하여 가이드라인 활용성 및 접근성을 높이고자 한다. 방법 : 임상시험 가이드라인 개발을 위해 총 9인으로 이루어진 위원회를 구성하고, 전반적인 절차를 수립하였다. 먼저, 가이드라인 집필위원회에서 관련된 국내외 가이드라인을 고찰하고, 감기에 대한 최신 임상시험 논문을 분석하여 초안을 완성하였다. 이후 대한한방내과학회 소속 전문가 자문위원회 검토 및 8인의 전문가로 구성된 협의회 자문을 통해 최종 가이드라인을 도출하였다. 결과 : 본 가이드라인은 (1) 일반적 사항 (2) 유효성 평가 기준 (3) 유효성 평가 방법 (4) 시험 대상자 선정 (5) 임상시험 설계 (6) 안전성 평가 (7) 감기 치료에서의 병용요법 (8) 한의학적 고려 사항의 8가지 범주로 나뉘어진다. 최종 개발된 가이드라인은 한의약임상시험센터 협의회와 대한한방내과학회의 인증을 득하였다. 결론 : 본 가이드라인은 감기 치료를 위한 임상시험을 수행하고 평가하는 데 유용하게 사용될 것이며, 이를 통해 신뢰할 수 있는 결과를 이끌어내고 정확한 해석을 용이하게 할 수 있을 것이라 기대된다. 또한 추후 해당 가이드라인 개정 및 관련된 호흡기질환 가이드라인 개발 과정에 도움을 줄 수 있을 것으로 사료된다.

Effects of the Lasater's Clinical Rubric of Debriefing in Advanced Cardiovascular Life Support Training (전문심폐소생술 교육에 Lasater의 임상판단 루브릭을 적용한 디브리핑의 효과)

  • Eun, Young;Bang, Sul-yeong
    • The Journal of the Korea Contents Association
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    • v.16 no.4
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    • pp.516-527
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    • 2016
  • The purpose of this study was to test the effects of the Lasater's debriefing on critical thinking disposition, problem- solving skills and clinical judgement of nursing students. The study design was a nonequivalent control group non synchronized design. The subjects were 60 students for 12 groups. They were randomly assigned to the experimental group (n=30) or control group (n=30). Critical thinking and problem-solving skills were measured using a self-administered questionnaire. Clinical judgement was measured by a Lasater's clinical judgement rubric. The Results of the study was : After Lasater's debriefing, the level of students' critical thinking, problem-solving skills and clinical judgment in experimental group were higher than the level of control group. Through this experiment the rubric of Lasater debriefing is an effective tool for clinical judgment, therefore we know that the future of simulation training is needed to use the Lasater's clinical judgement rubric of debriefing in simulation training.

Dental hygiene students' stress during clinical practices (치위생과 재학생의 임상실습 스트레스 요인)

  • Oh, na-rae;Jeong, mi-ae
    • Proceedings of the Korea Contents Association Conference
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    • 2018.05a
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    • pp.395-396
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    • 2018
  • 본 연구는 치위생과 재학생들의 교외 임상실습과정에서 느끼는 스트레스를 파악하고 이를 관리하는 프로그램을 개발하는데 기초자료로 사용하고자 실시하였다. 대구 경북지역 치위생과 재학생을 대상으로 자기기입식 설문조사를 실시하여 전공만족도와 실습기관의 유형이 임상실습 스트레스에 영향을 미치는 것으로 나타났다. 향후 치과환경에 학생들의 스트레스를 대처할 수 있는 대처방안의 개발이 필요할 것이라 사료된다.

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A MORPHOMETRIC STUDY ON THE PRIMARY MOLARS AND PREFORMED STAINLESS STEEL CROWN (유구치 치관 및 기성금속관의 크기에 관한 계측학적 연구)

  • Choi, Ji-Eun;Cheong, Tae-Sung;Kim, Shin
    • Journal of the korean academy of Pediatric Dentistry
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    • v.28 no.3
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    • pp.355-362
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    • 2001
  • Data derived from odontometric studies are useful in many areas. Especially crown diameter of primary teeth is important in not only anthropology but also clinical dentistry. The purposes of this study were to compare diameters of primary molars of Korean children with those of preformed stainless steel crown, and examine racial characteristics of primary molars of Korean children. The mesiodistal and buccolingual diameters of primary molars were measured on dental casts taken from 235 children(male 105, female 131), with digital calipers. And the data were compared with those of preformed stainless steel crowns. The results were as follows; 1. No significant difference was observed between the right and left members of antimeric teeth and all primary molars of male were larger than those of female. 2. The diameters of primary molars of Korean are smaller than those of Austrailian aborigines and there was significant difference between diameters of primary molars of Korean and those of other populations. 3. There were size differences between diameters of maxillary, mandibular first molar and preformed stainless steel crown than other primary molars, relatively.

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Clinical Features Affecting Antipsychotic Prescription for Delirium Patients (섬망 환자에서 항정신병약물 처방에 영향을 주는 임상적 특징)

  • Kim, Jongwon;Kim, Min-Hyuk;Paik, Soo-Hyun
    • Korean Journal of Psychosomatic Medicine
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    • v.27 no.2
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    • pp.111-118
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    • 2019
  • Objectives : The purpose of this study was to investigate the clinical characteristics of antipsychotic medication prescription for the symptom control in patients with delirium. Methods : One hundred and eighty-five patients referred to consultation-liaison psychiatric services for delirium due to general medical condition were included in this study. All subjects were divided into two groups (antipsychotics users vs. antipsychotics nonusers), and comparison analyses on their clinical characteristics were performed. Results : One hundred and twenty nine patients (66.5%) used antipsychotics for their delirium, and 56 patients (30.3%) did not use antipsychotics. The history of psychotropic medication was more frequently observed in antipsychotic users (5.4% vs. 18.6%, χ2=5.498, p=0.022). Especially, the history of benzodiazepine use was significantly high in antipsychotics users. The total score and sub-items of delirium rating scale-severity items except for the psychomotor retardation item showed higher scores in antipsychotic users than in nonusers (all p<0.05). The total score of the delirium rating scale-diagnosis items was higher in antipsychotic users than in the nonusers (p=0.010). Conclusions : Delirium patients with more severe delirium symptoms and with more history of benzodiazepine use were treated with antipsychotics more frequently than those without. These findings imply that benzodiazepine may not only exacerbate delirium but be associated with aggression or psychomotor agitation that need immediate intervention. Clinicians may need to pay attention not only these external symptoms but also to hypoactive symptoms that may lead to misdiagnosis and undertreatment.

Comparison of the nonlinear dynamics of EEG signals (EEG 신호의 비선형 동역학의 비교)

  • 신동선;조한범;김응수
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2001.05a
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    • pp.179-182
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    • 2001
  • 인체 활동에 따라 우리 몸에는 다양한 전기적 생체신호가 발생하며 특히 뇌의 활동에 따라 발생되는 뇌파(EEG)는 비침습적 방법으로 측정될 수 있는 장점 때문에 뇌기능 연구 및 임상 등에서 널리 사용되어지고 있다. 또한 임상에서는 주로 뇌 신경계 질환환자의 병인 규명 및 기전 연구를 위하여 뇌파가 사용되어지고 있다. 최근에는 컴퓨터 발달에 따라 카오스, 비선형 이론 등의 다양한 방법으로 복잡한 시계열 신호인 뇌파를 분석하는 기법들이 개발되어 뇌파의 특징점을 찾아 임상에 활용하거나 뇌기능 연구에 적용하려는 연구가 진행되고 있다. 본 논문에서는 잡화(artifact)가 섞여 있는 뇌파신호 및 artifact가 제거된 다음 재구성된 뇌파신호(reconstructed EEG signal), 그리고 독립성분으로 분리된 각각의 신호에 대하여 특징점을 찾기 위하여 비선형 및 선형 분석을 실시하여 유의한 차이점을 밝혔다.

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The Necessity of Independent Data Monitoring Committee in Domestic Clinical Trials (현재 국내임상시험에서 독립적 자료모니터링위원회의 필요성)

  • Kang, Seung-Ho
    • The Korean Journal of Applied Statistics
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    • v.22 no.2
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    • pp.317-327
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    • 2009
  • In adaptive designs important components of clinical trials may be changed based on the results of interim analysis. Several international guidelines point out that such interim analysis should be performed by independent experts who do not participate in clinical trials when adaptive designs are used in therapeutic confirmatory clinical trials, and if not, it may cause bias. The international guidelines recommend the establishment of independent data monitoring committee for conducting interim analysis independently.

A Study of on the Forest Map Update Using Orthorecified High Resolution Satellite Imagery Data (고해상도 정사위성영상을 이용한 임상도 수정에 관한 연구)

  • 성천경;조정호
    • Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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    • 2004.03a
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    • pp.571-577
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    • 2004
  • The operational availability of multispactal high-resolution satellite imagery, opens up new possibilities for updating forest stand map. Compared with information acquired by traditional methods (Panchromatic Aerial Photo), these data offer a number of advantages, In this study used 1m resolution and 4 band multispectral, which are capability to update forest map of kind of tree. Therefore, high-resolution satellite imagery is good method for updating forest map in the future.

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