• Title/Summary/Keyword: 임상결과

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Needs for clinical dietitian in hospital settings: Importance of doctor's awareness regarding clinical nutrition service as mediating variable (의료기관 임상영양사 요구도에 미치는 영향 : 임상영양서비스의 중요도에 대한 의사의 인식을 매개역할 중심으로)

  • Um, Mi Hyang;Park, Yoo Kyoung;Song, Yoon Mi;Lee, Song Mi;Lyu, Eun Soon
    • Journal of Nutrition and Health
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    • v.50 no.5
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    • pp.519-529
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    • 2017
  • Purpose: The purpose of this study was to explore whether or not there is a relationship between doctor's awareness of clinical nutrition service and needs for a clinical dietitian. Methods: A cross-sectional survey design was used. The research was carried out by using questionnaires that had been specifically designed for the study. The research was conducted from September to October, 2013 for 311 doctors at 43 hospitals (with over 400 beds). Frequency analysis, factor analysis, reliability analysis, confirmatory factor analysis, and bootstrapping analysis were conducted using SPSS 21.0. Results: 'Implementation of clinical nutritional service' (p < 0.001) and 'usefulness on clinical nutrition service' (p < 0.001) were found to be correlated with 'importance of clinical nutrition service' as an independent variable. The correlation between 'importance of clinical nutrition service' as a mediating variable and 'needs for clinical dietitian' as a dependent variable was also confirmed (p < 0.001). The results of the bootstrapping test showed that the mediating effect of 'importance of clinical nutrition service' was significant. The indirect effect value between 'implementation of clinical nutrition service' and 'needs for clinical dietitian' was 0.040, indirect effect value between 'usefulness on clinical nutrition service' and 'needs for clinical dietitian' was 0.095. Conclusion: The frequency of providing clinical nutritional services, the quality of clinical nutritional services, and the degree of implementation of clinical nutritional services were found to be important for positive perception of clinical nutrition services by doctors. Therefore, proper provision of clinical nutrition services and effective therapeutic effects will be continuously highlighted, which will increase the awareness of the physician and ultimately increase the demand for clinical nutrition service.

Exenatide: a New Agent for the Treatment of type 2 Diabetes Mellitus as Adjunctive Therapy

  • Yoo, Ju-No;Yoo, Dong-Joo;Yoo, Bong-Kyu
    • Korean Journal of Clinical Pharmacy
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    • v.15 no.2
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    • pp.165-172
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    • 2005
  • 엑세나타이드는 2005년 4월에 미국 FDA로부터 허가된 새로운 계열의 당뇨병치료제로서 적응증은 멧포르민이나 설포닐유레아계열의 당뇨병치료제로서 치료를 받고 있음에도 불구하고 혈당이 목표치로 저하되지 않는 제2형 당뇨병환자에게 기존의 치료법에 부가적으로 사용하는 것으로 제한되어 있다. 엑세나타이드는 39개의 아미노산으로 구성되어 있으며 미국 캘리포니아주에 자생하는 도마뱀의 타액에서 유래된 물질과 조성과 기능이 유사하도록 합성된 펩타이드 약물이다. 이 약물은 혈중포도당의 농도에 의존적으로 인슐린분비를 촉진하며, 비정상적으로 높은 혈중 글루카곤농도를 저하시키며, 음식물의 위통과시간을 연장하며, 식욕을 저하시키는 등의 여러 가지 기전을 통하여 혈당을 조절하는 것으로 알려져 있다. 멧포르민으로 1일 1500 mg을 사용하고 있는데도 불구하고 당화혈색소가 7%를 초과하는 제2형 당뇨병환자 336명을 대상으로 부가적으로 30주간 엑세나타이드 $5{\mu}g$또는 $10{\mu}g$을 1일 2회 피하주사 한 임상시험결과에 의하면, 당화혈색소가 7% 미만인 환자의 비율은 intent-to-treat 로서 각각 27%와 40%로 나타났다. 이는 기존의 치료법과 위약으로 치료받은 군에서의 13%에 비하여 통계적으로 매우 유의성 있는 결과인 것으로 분석되었다(p<0.01). 또 다른 임상시험에서는 상기 임상시험과 유사한 임상시험계획을 바탕으로 하여 설포닐유레아로 치료받고 있었지만 당화혈색소가 7%를 초과하는 제2형 당뇨병환자를 대상으로 임상시험을 실시하였으며, 그 결과에 의하면 엑세나타이드와 설포닐유레아의 병용치료 시 혈당조절에 매우 유리한 것으로 나타났다. 멧포르민과 설포닐유레아의 병용요법으로 치료받고 있던 당뇨병환자를 대상으로 실시한 임상시험에서도 동일한 결과가 나타났다. 이 약의 부작용은 치료개시 후 나타나는 메스꺼움이 문제로 지적되었으며 저 혈당현상은 큰 문제가 되지 않는 것으로 나타났다. 이 약은 인슐린 대용약물이 될 수 없으며 당뇨병성 케토산증의 치료에 사용할 수 없다. 또한 이 약물은 심한 신부전이 있거나 말기신장질환 환자에게 사용해서는 안 된다.

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The Effects of Clinical Practice Stress, Grit and Self-Efficacy on Clinical Competency in Nursing Students (간호대학생의 임상실습 스트레스, 그릿, 자기효능감이 임상 수행 능력에 미치는 영향)

  • Kim, Young-Sook
    • The Journal of the Korea Contents Association
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    • v.22 no.9
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    • pp.451-460
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    • 2022
  • This study was conducted to understand the correlation between clinical practice stress, grit, self-efficacy, and clinical performance of nursing students and to identify factors affecting clinical performance. A survey was conducted on 160 students in 3rd and 4th grade students enrolled in a nursing department located in G city. As a result of the study, clinical performance was negatively correlated with clinical practice stress(r=-.383, p< .001) and positively correlated with grit(r=.310, p< .001), self-efficacy (r=.327, p< .001). Factors affecting the clinical performance of nursing students were clinical practice stress(β=-.37, p<.001), clinical practice satisfaction (β=.35, p< .001), self-efficacy (β=.31, p< .001), grit (β=.28, p< .001) and the explanatory power was 42.8%. Based on the results of this study, in order to improve the clinical performance of nursing students, it is necessary to reduce the clinical practice stress and make them satisfied with the clinical practice. In addition, it is necessary to develop a program to improve self-efficacy and grit

Convergence Relationship between Clinical Practice Stress after Gerontological Nursing Practice, Clinical Practice Satisfaction and Nursing Image of Nursing College Students (간호대학생의 노인간호학 실습 후 임상실습 스트레스, 임상실습 만족도 및 간호이미지와의 융복합적 관련성)

  • Kim, Moon-Ok;Cha, Ju-Ae
    • Journal of Digital Convergence
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    • v.16 no.9
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    • pp.247-256
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    • 2018
  • The purpose of this study was to investigate the relationship between clinical practice stress, practice satisfaction, and nursing image of nursing students with experience of Gerontological nursing practice and to identify factors affecting nursing image. Data were collected from 150 nursing students from September 1 to 23, 2016 and analyzed using SPSS / Win 23.0. Results showed, practise stress was 3.13, satisfaction, 3.14 and nursing image, 3.32. Correlation analysis revealed that there was negative correlation between practice stress and practicec satisfaction, practice stress and nursing image, and a positive correlation between nursing image and practice satisfaction. Meanwhile, the factor affecting nursing image was practice satisfaction (${\beta}=.602$) and the explanatory power was 40%. Therefore, effective nursing education and practical strategies are needed to improve the nursing image and practice satisfaction of Gerontological nursing practice of nursing students.

Development of Clinical Trial Guidelines for Using Korean Herbal Medicine in Treatment of Common Cold (감기 치료를 위한 한약제제 임상시험 가이드라인 개발)

  • Jiwon Park;Kwan-Il Kim
    • Journal of Society of Preventive Korean Medicine
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    • v.28 no.1
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    • pp.131-157
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    • 2024
  • 목적 : 본 연구는 감기에 대한 한약제제 임상시험을 수행하고 평가하는 데 보편적인 원칙을 제공하는 가이드라인 개발과정 및 내용을 소개하여 가이드라인 활용성 및 접근성을 높이고자 한다. 방법 : 임상시험 가이드라인 개발을 위해 총 9인으로 이루어진 위원회를 구성하고, 전반적인 절차를 수립하였다. 먼저, 가이드라인 집필위원회에서 관련된 국내외 가이드라인을 고찰하고, 감기에 대한 최신 임상시험 논문을 분석하여 초안을 완성하였다. 이후 대한한방내과학회 소속 전문가 자문위원회 검토 및 8인의 전문가로 구성된 협의회 자문을 통해 최종 가이드라인을 도출하였다. 결과 : 본 가이드라인은 (1) 일반적 사항 (2) 유효성 평가 기준 (3) 유효성 평가 방법 (4) 시험 대상자 선정 (5) 임상시험 설계 (6) 안전성 평가 (7) 감기 치료에서의 병용요법 (8) 한의학적 고려 사항의 8가지 범주로 나뉘어진다. 최종 개발된 가이드라인은 한의약임상시험센터 협의회와 대한한방내과학회의 인증을 득하였다. 결론 : 본 가이드라인은 감기 치료를 위한 임상시험을 수행하고 평가하는 데 유용하게 사용될 것이며, 이를 통해 신뢰할 수 있는 결과를 이끌어내고 정확한 해석을 용이하게 할 수 있을 것이라 기대된다. 또한 추후 해당 가이드라인 개정 및 관련된 호흡기질환 가이드라인 개발 과정에 도움을 줄 수 있을 것으로 사료된다.

Quality Improvement of Clinical Practice in Nursing Students : Focused on Delivery Room Clinical Practice (간호대학생의 분만실 임상실습 질 향상 방안)

  • Chun, Nami;Noh, Gie-Ok
    • The Journal of the Korea Contents Association
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    • v.16 no.7
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    • pp.513-521
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    • 2016
  • Purpose of this study was to provide strategies to improve quality in clinical practice by identifying the nursing student contents of clinical practice, performance level and satisfaction in the delivery room setting and correlations between the performance level and satisfaction. As the result, Nursing students were mostly rely on observational experiences with very limited experiences of performance and assist. Nursing students' clinical practice satisfaction were relatively low with 69 percentile score. The women's health clinic group showed higher score on frequency of clinical observation, clinical practice satisfaction than the tertiary hospital group. Correlations among frequencies of observation, assist and satisfaction were identified. Simulation based clinical practice as alternative ways to enhance students' performance level, utilizing community based speciality healthcare facilities for clinical practice, increasing observational experiences in the clinical field were suggested as strategies to improve quality of nursing clinical practice and ultimately to improve quality of healthcare services.

Effects of Preceptorship on Nursing Students' Clinical Competency, Stress of Clinical Practice, and Practice Satisfaction in Clinical Practice (프리셉터십 적용이 간호학생의 임상수행능력, 임상실습 스트레스, 임상실습 만족도에 미치는 효과)

  • Hong, Sung-Jung;Kim, Eunhee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.10
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    • pp.6204-6214
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    • 2014
  • This study examined effects of preceptorship in a clinical maternity nursing course. The study design was a quasi-experimental, nonequivalent control group post-test design. The control groups (n=70, from July to October, 2012) participated in traditional practice method and the experimental groups (n=70, from December, 2012, to February, 2013) participated by a preceptor who attended a systematic preceptor education program. The data analyzed included the numbers, percentages, mean, standard deviation, and t-test using SPSS 19.0/WIN. In the experimental group, the clinical competency and practice satisfaction showed significantly higher scores, and the stress of clinical practice showed significantly lower scores than control group. Consequently, the preceptorship was effective in clinical maternity nursing education for student nurses and it is necessary to adapt this many areas in the clinical nursing education field for nursing students.

Relationship Between Nursing Students Simulation Practice Education, Clinical Practice Satisfaction, Problem-solving Ability and Clinical Performance Ability (간호대학생의 시뮬레이션 실습교육 경험, 임상실습만족도, 문제해결능력 및 임상수행능력과의 관계)

  • Yang Hyunmi
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.3
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    • pp.219-226
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    • 2024
  • The purpose of this study is to determine the between nursing students simulation pratice education experience, clinical practice satisfaction, problem-solving ability, and clinical performance ability. The research design was a descriptive correlational study, and the participants were third-year nursing students. A total of 197 people were involved, including 95 students from a university with simulation training in the curriculum and 102 students from a university without simulation training in the curriculum. It was composed. Frequency analysis, descriptive statistics, independent t-test, and pearson correlation were used to analyze the collected data. As a result of the study, nursing students who had experience in simulation practice education showed significant differences in clinical practice satisfaction and clinical performance ability during clinical practice. However, there was no significant difference in problem-solving ability. In addition, it was confirmed that there was a correlation between simulation training experience, clinical practice satisfaction, and clinical performance ability. Based on the results of this study, it will be possible to develop and utilize simulation education programs in various situations to increase the effectiveness of clinical practice for nursing students.

The Correlation Analysis Between Soil Bacterial Community and Growth Characteristics of Wild-simulated Ginseng (Panax ginseng C. A. Mey er) in Different Forest Phy siognomy (임상별 토양세균군집과 산양삼 생육특성 간의 상관관계 분석)

  • Kiyoon Kim;Hyun-Jun Kim;Yurry Um;Dae-Hui Jeong;Jeong-Hoon Huh;Kwon-Seok Jeon
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.08a
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    • pp.61-61
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    • 2020
  • 본 연구는 우리나라 임상 중에서 침엽수림과 침활혼효림으로 구성된 산양삼 시험포지를 선정하고, 임상별 토양의 토양세균군집을 분석하여 산양삼 생육특성과의 상관관계 구명하고자 수행하였다. 산양삼 시험포지는 침염수림으로 구성된 충주 산양삼 종자공급단지와 침활혼효림으로 구성된 함양 산양삼 종자공급단지를 선정하여 각각 조성하였다. 토양세균군집 분석은 pyrosequencing analysis (Illumina platform)를 이용하였고, 토양세균군집과 생육특성 간의 상관관계는 Pearson's correlation을 이용하여 분석하였다. 임상별 시험포지의 토양세균은 두 시험포지 모두 Acidobacteria가 우점종으로 확인되었다. 주좌표 분석을 통해 임상별 산양삼 시험포지에서 우점하는 토양세균 군집을 확인한 결과, 먼저 토양세균 군집은 임상별 시험포지에 따라 군집화를 이루는 것으로 확인되었고, Pearson's 상관관계 분석 결과, 토양세균 군집의 상대적 빈도수는 수종 비율에 따라 상이한 상관관계를 보이는 것으로 확인되었다. 이 중에서 Proteobacteria, Alphaproteobacteria, Actinobacteria_class, Phycisphaerae는 침엽수의 비율과 유의적인 정의 상관관계를 보였고, Nitrospirae, Chlamydiae, Planctomycetia, Acidobacteria_6는 활엽수의 비율과 유의적인 정의 상관관계를 보이는 것으로 나타났다. 또한 임상별 산양삼 시험포지의 토양세균 군집과 산양삼 생육특성 간의 상관관계를 분석한 결과, Nitrospirae, Chlorobi, Planctomycetia, Acidobacteria_6가 산양삼의 생육과 유의적인 정의 상관관계를 보였다. 본 연구결과를 바탕으로 다양한 산림환경에서 토양세균군집과 산양삼 생육특성 간의 상관관계를 명확하게 구명할 수 있다면 향후 산양삼의 최적 재배지를 선정하는데 있어 도움을 줄 수 있을 것으로 사료된다.

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