• The Korean Journal of Applied Statistics
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• v.14 no.2
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• pp.429-437
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• 2001

단순 이단계 표본 추출의 경우에 최적 선택률은 Hansen과 Hurwitz(1949)에 의하여 구하여졌다. 그러나 통계청에서 실시하는 표본조사등은 층화 이단계 추출을 한다. 따라서 실제적인 필요성에 의하여 층화 2단계 표본 설계를 시도 하였다. 층화 이단계 표본추출시에 주어진 비용아래서 모총계의 추정량의 분산을 최소로 하는 최적의 선택확률(optimum selection probability), 표본추출율과 부차 표본추출율을 Lagrangean 승수법에 의하여 구한다.

• KSBB Journal
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• v.22 no.2
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• pp.73-77
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• 2007

The effects of Fucoidan extracted from Ulva lactuca on carbon tetrachloride ($CCI_4$)-induced dysfunction in $CCI_4$-posttreated rats were investigated. Ulva lactuca fucoidan (ULF) of 100 mg/kg concentration was intraperitoneally administered into rats at dose of 1 ml/kg for 14 days. On the day 15, 3.3 ml/kg of $CCI_4$ dissolved in olive oil (1 : 1) was injected 12 hours before anesthetization. We examined the levels of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) in serum of rats, superoxide dismutase (SOD) in mitochondrial fraction and catalase (CAT), glutathione peroxidase (GPx), malondialdehyde (MDA) in liver of rats. SOD, CAT, GPx decreased, and GOT, GPT, MDA increased in the $CCI_4$-treated group. But SOD, CAT, GPx increased, and GOP, GPT, MDA decreased in the ULF and $CCI_4$-treated group. These results showed that ULF had the protective effects on the liver dysfunction of $CCI_4$-treated rats.

• The Korean Journal of Applied Statistics
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• v.24 no.2
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• pp.393-400
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• 2011

In a large scale survey, cluster sampling design in which a set of observation units called clusters are selected is often used to satisfy practical restrictions on time and cost. Especially, a two stage cluster sampling design is preferred when a strong intra-class correlation exists among observation units. The sample Primary Sampling Unit(PSU) and Secondary Sampling Unit(SSU) size for a two stage cluster sample is determined by the survey cost and precision of the estimator calculated. For this study, we derive the optimal sample PSU and SSU size when the population SSU size across the PSU are di erent by extending the result obtained under the assumption that all PSU have the same number of SSU. The results on the sample size are then applied to the $4^{th}$ Korea Hospital Discharge results and is compared to the conventional method. We also propose the optimal sample SSU (discharged patients) size for the $7^{th}$ Korea Hospital Discharge Survey.

• Proceedings of the KAIS Fall Conference
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• 2011.05a
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• pp.64-66
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• 2011

최근 웰빙에 대한 사회적 관심이 증가하면서 다양한 기능성 식품들이 앞다퉈 개발되고 있다. 본 논문에서는 제주산 감태에서 추출한 후코이단이라는 해조류 추출물 성분을 이용하여 기능성 차를 개발하였다. 후코이단은 암의 치료에 효능이 있을 뿐만 아니라 뇌의 혈액 개선의 효과가 있으며, 면역력 증강작용, 혈액응고 저지 작용, 비만억재와 당뇨 치료에도 효과가 있다. 후코이단은 분말가루, 액상형, 과립형 등으로 시판되고 있다. 하지만 홍보가 미약하여 많이 알려져 있지 않고 있으며 또한 항암작용에 대한 기능만이 부각되어 있어 오히려 소비확대가 이루어지지 않고 있다. 본 논문에서는 일반적으로 사람들이 쉽게 접할 수 있는 식품을 통해 후코이단의 섭취를 권장할 수 있는 올레차를 개발하였으며, 후코이단 특유의 비릿한 향을 중화하기 위해 제주의 유채꽃과 꿀을 이용하였다.

• Journal of Life Science
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• v.16 no.7 s.80
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• pp.1104-1108
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• 2006

The purpose of this study was to investigated the effects of Laminaria japonica fucoidan extract (LJFE) through the enzymatic regulation against the hepatotoxicity-inducing carbon tetrachloride $(CCl_4)$ in LJFE and $CCl_4-treated$ rats. LJFE of 100mg/kg concentration was intraperitoneally administered into rats at dose of 1.5m11kg for 14 days. On the day 15, 3.3ml/kg of $CCl_4$ dissolved in olive oil (1:1) was injected 12 hours before anesthetization. We examined the levels of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) in serum of rats, superoxide dismutase(SOD) in mitochondrial fraction, and catalase(CAT), glutathione peroxidase(GPx) in liver homogenate. $CCl_4-treatment$ markedly increased the levels of GOT and GPT, and significantly decreased those of SOD, CAT and GPx. But LIFE pretreatment decreased the levels of GOT and GPT, by 40% and 64%, respectively and increased those of SOD, CAT and GPx, by 114%, 36.1% and 55.9%, respectively These results showed the LIFE had the enzymatic regulatory effects against the hepatotoxicity-inducing $CCl_4$ in the preventive way.

• The Korean Journal of Applied Statistics
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• v.8 no.2
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• pp.99-108
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• 1995

When modeling a complicated system with a computer model, it is of vital importance to choos input values efficiently. The Latin Hypercube sampling (LHS) proposed by MaKay et al.(1979) has been most widely used for choosing input values for a computer model. We propose the two-stage Latin Hypercube sampling(TLHS) which is an improved version of the LHS for procucing input values in estimating the excectation of a function of the output variable. The proposed method is applied to simulation study of the performance of a printer actuator and it is shown to outperform the other sampling methods including the LHS in accuracy.

• Bulletin of the Korean Mathematical Society
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• v.10 no.2
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• pp.69-75
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• 1973

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.6
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• pp.1287-1295
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• 2015

This research is the study on the comparative evaluation of SPC (Staggered Pedestrian Crossings) vs PC (Pedestrian Crossings) using risk analysis. Accident factor was elicited by survey of driver's and pedestrian's at SPC & PC. I estimated the weight of a risk of violation and a mental burden by AHP (Analytic Hierarchy Process) and compared degree of risk at SPC AND PC. In conclusion, a new alternative plan of a pedestrian crossing system, staggered pedestrian crossing which plays an important role in traffic flow, pedestrian's crossings which plats an important role in traffic flow, pedestrian's convenience and traffic safer is sager than pedestrian crossings the degree of risk used this study doesn't imply an measure of the number of accident and the rate of accident, in estimating the degree of risk of pedestrian crossings, we should analyze more data of accident, behaviors, and road circumstance to include driver's and pedestrian's violation behavior in an estimate index.

• Food Science of Animal Resources
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• v.29 no.1
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• pp.34-39
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• 2009

The objective of this study was investigated to apply the fucoidan and laminarin extract from low-grade Undaria pinnatifida to real food product, a pork patty. Pork patties added with fucoidan and laminarin showed lower lipid oxidation and the inhibition against lipid oxidation was shown to be dependent on the irradiation doses. The Hunter color values of pork patty added with fucoidan increased significantly with an increase of irradiation dose. The hardness profiles of the patties with fucoidan and laminarin was decreased, but the amount of water in the patties was increased. Also, the combination of gamma irradiation and addition of fucoidan and laminarin was shown to be effective for the microbiological control. These results suggested that gamma irradiation and fucoidan and laminarin treatment showed the positive effect on microbial stability and quality of the pork patty.

• Korean Chemical Engineering Research
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• v.50 no.4
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• pp.604-609
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• 2012

Properties of fucoidan used for functional cosmetic ingredients and the effect of fucoidan molecular weight on the cosmetic functions were studied. Fucoidan was extracted from Undaria pinnatifida sporophylls and molecular weight (35~160 kDa) of fucoidan was controlled by contact glow discharge electrolysis (CGDE). To test possibility of fucoidan as a cosmetics material, tyrosinase inhibition property, water-holding property, elastase activity inhibition property and DPPH free radical scavenging property were measured. Water-holding property of fucoidan was higher than that of hyaruronic acid, which is known as the one of the best water-holding material. The water-holding strength of fucoidan slightly increase as molecular weight of fucoidan decrease. Elastase activity inhibition (anti wrinkle effect) of fucoidan was higher than that of adenosine using standard material for anti wrinkle test. Optimum molecular weight of fucoidan to obtain highest tyrosin inhibition effect, elastase inhibition effect and radical scavenger effect is 100 kDa.