• Membrane Journal
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• v.27 no.6
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• pp.511-518
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• 2017

The membrane emulsification (ME) is a technology for producing emulsions with narrow size distribution by using the well-defined porous membranes such as the SPG membrane. In this study, the preparation of polycaprolactone (PCL) microcapsules by using the multiple emulsions obtained from membrane emulsification method is studied. After the making of $W_1/O$ single emulsions by sonication method, then $W_1/O/W_2$ multiple emulsions are formed by premix-ME method. The PCL microcapsules impregnated with BSA model drug are prepared by solvent evaporating from $W_1/O/W_2$ multiple emulsions. The effects of various parameters such as the ratio of disperse/continuous phase (D/C ratio), the concentration of PCL, emulsifier and model drug and the transmembrane pressure on the size and distribution of PCL microcapsules are investigated. The uniform PCL microcapsules with about $5{\sim}6{\mu}m$ of mean size and 26% of BSA loading are obtained by the premix membrane emulsification.

• Journal of the Korean Applied Science and Technology
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• v.34 no.3
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• pp.545-554
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• 2017

This study is concerned with the stability of liquid crystal forming emulsifier with localized depend on change of pH using liquid crystal forming agent of advanced company. The liquid crystal emulsifying agent was localized using Sugar Crystal-LC (bio-tech Co., Ltd., Korea), and comparative samples were measured by using Nikkomulese-LC (Nikko Camicarls, Japan) and Alacel-LC (Croda Camicarls, UK). Liquid crystal formation was confirmed microscopically to show the formation of liquid crystal structure at acidic (pH=4.2), neutral (pH=7.0) and alkaline (pH=11.7). The particles of the liquid crystal were observed with a polarizing microscope according to the stirring speed. The stirring time was all the same for 3 minutes with a homo-mixer, and the stirring speed was increased to 2500 rpm, 3500 rpm and 4500 rpm to observe the liquid crystal state. As a result, it was found that the Korean surfactant was more stable and clear liquid crystal structure was formed than the two foreign acids. In the case of the UK in acid zone, the emulsion particle size was uniform and unstable. In the case of Japanese surfactant, it has similar structure and performance to those of localized Korean. It was found that Korean surfactant had superior emulsifying performance in acid zone compared with foreign products. It is possible to develop various formulations such as liquid crystal cream, lotion, eye cream, etc. using Sugar Crystal-LC emulsifier as an application cosmetic field, and it is expected that it can be widely applied as emulsifying technology for skin care external application in the pharmaceutical industry and the pharmaceutical industry as well as the cosmetics industry.

• Journal of the Korean Society of Food Science and Nutrition
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• v.11 no.1
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• pp.45-49
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• 1982

This study aims to substitute the emulsifier and gelifier for the poly phosphates with regard to diminishing the foreign phosphates in diet and production cost. It is desirable to introduce the application of theory for melting phenomenon in this investigation since the rate of peptisation is very representative index during the conversion of Ca-paracaseinate to Na-paracaseinate in processed cheese. It will be impossible to substitute completely for polyphosphates but partial substitution could be possible if one consider the organoleptic quality of typical processed cheese.

• Proceedings of the Korean Institute of Industrial Safety Conference
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• 2003.10a
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• pp.148-153
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• 2003

고분자 물질은 유기용제를 사용하여 제조되는 경우가 일반적이다. 이들 중에서 용제형 아크릴계 고분자는 점착강도, 내습성, 내수성 그리고 내열성 등이 우수하여 페인트, 접ㆍ점착제, 섬유 등의 산업전반에 이용되고 있으나 용제사용에 따른 화재의 위험성과 환경적인 문제점 때문에 규제의 대상이 되고 있다. 이러한 위험성과 환경문제점은 유화중합법에 의해 고분자물질을 제조함으로써 해결되며, 그 중에서 단계 유화중합법은 다른 중합법에 비해 온도조절이 용이하며, 반응속도와 분자량을 조절할 수 있다는 장점 때문에 latex 공업이나 고분자 blending 기술면에서 많이 이용되고 있는 실정이다.(중략)

• Bulletin of Food Technology
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• v.9 no.2
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• pp.173-180
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• 1996

필자들은 96년 4월 28일부터 5월 6일까지 8박 9일간 미국 Indiana주의 Indianapolis에서 열린 미국유화학회에 참석하여 "초임계유체로 추출한 들기름의 특성과 산화안전성"에 관한 논문을 발표하고, 학회 개최지에서 약 3시간 정도 떨어진 Peoria에 위치한 USDA를 방문하여 유지 관련분야의 최근동향 및 연구과제를 탐색하였다. 또한 시카코에서 5월 5일부터 5월 8일까지 열리는 Food Marketing institute에 참석하여 식품에 관련된 신제품의 개발 현황과 수퍼마켓의 운영방법에 대한 것을 살펴보았다.

• Proceedings of the KOSOMBE Conference
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• v.1992 no.11
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• pp.157-160
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• 1992

표면에 여러 가지 기능성기를 가지는 microspheres는 immunoassay, drug delivery system, cell separation등 의용공학분야에 응용이 기대되고 있다. 이들 분야의 응용을 위하여 유화제를 사용하지 않으면서, 기존의 회분식, 반회분식, seed 중합법등의 문제점을 극복한 two stage shot growth technique올 개발하여 여러 가지 기능성기가 표면에 도입된 microspheres를 제조하였으며, 응용의 전단계로서 이들 microspheres에 대한 모델 단백질(BSA)의 흡착실험을 pH, 기능 성기의 종류와 양, BSA농도를 변수로 행하여 최대 흡착량을 보이는 조건을 결정하였다.

• Safe Food
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• v.6 no.3
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• pp.3-10
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• 2011

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2001.05a
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• pp.172-173
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• 2001

젤라틴은 일반적으로 콜라겐의 가수 분해로 생성되어지는 단백질로서 대부분 동물의 결합 조직이나 피부, 배에 존재한다. 젤라틴은 젤리, 제빵 및 제과, 유화제 및 chewing gum base 등과 같은 식품용은 물론이고, 의약용, 사진용, 미생물 배양용 등으로도 사용되어 지고 있다. 젤라틴은 대부분 돼지나 소와 같은 육상 동물에서 얻어지고 있으나 최근 들어 광우병과 구제역과 같은 안전상의 문제가 대두되는 시점에서 그들의 대체 원료가 필요로 하게 되었고 이들을 대신하기 위해 어류에서 추출한 젤라틴에 많은 관심을 보이고 있다. (중략)

• Applied Chemistry for Engineering
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• v.31 no.4
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• pp.429-437
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• 2020

In this study, a cationic gemini surfactant was synthesized using isosorbide, in order to modify the alkyl chain length in the range of C₁₀~C₁₆. The c.m.c and surface tension of the synthesized cationic gemini surfactant were measured to be in the ranges of 5.13 × 10^-4~1.62 × 10^-4 mol/L and 31.86~37.41 dyne/cm, respectively. The surface tension increased with increasing the length of the alkyl group. In addition, as the area per molecule occupied by the surfactant adsorbed on the interface increased with the reduced extent of adsorption, the bubble generation at the air-water interface decreased. The emulsifying capacity in benzene was maintained above 60 ± 5% after 8 h while that in soybean oil tended to decrease above 50 ± 5%. The performance was superior in benzene, a highly hydrophobic substance, and the emulsion stability was shown to be consistent beyond 1 h during the preparation of pre-emulsion in oil and water. The antimicrobial activity was dependent on the length of the hydrophobic chain of the synthesized cationic gemini surfactant due to the increased size of the clean zone in Escherichia coli (E.coli) and Staphylococcus aureus.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.147-153
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• 2018

PLGA microcapsule particles encapsulating BSA aqueous solutions were prepared using a water-in-oil-in-water emulsion method. The morphology, particle size, BSA encapsulating efficiency, and in-vitro release test were also studied using the microcapsule particles. In the outer aqueous phase, an emulsifier, e.g., PVA, was replaced with metal salts for surface solidification. Scanning electron microscopy (SEM) showed that the microcapsule particles had smooth surfaces and were between $1{\mu}m$ and $7{\mu}m$ in size. The microcapsule particle morphology was affected directly by the ratio between the polymer solution and inner aqueous solution, and composition of the outer aqueous solution. The factors also partially affected the BSA encapsulation efficiencies and in-vitro release rates. All the microcapsule particles showed an initial burst release through the in-vitro release test. On the other hand, the particles also showed a relatively long release period. Metal salts could be good choices to replace the emulsifier to solidify the microcapsule particle surfaces.