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http://dx.doi.org/10.12925/jkocs.2017.34.3.545

A Study on the Formation of Liquid Crystalline Structure depend on pH Change in O/W Emulsion  

Kim, Ji-Seop (Dept. of Bio-chemistry, Yang Young Digital High School)
Hong, Jin-Ho (Dept. of Bio-chemistry, Yang Young Digital High School)
Jeon, Mi-Kyeong (Dept. of Bio-chemistry, Yang Young Digital High School)
Kim, In-Young (Bio- R&D Center, Biobeautech Co., Ltd.)
Publication Information
Journal of the Korean Applied Science and Technology / v.34, no.3, 2017 , pp. 545-554 More about this Journal
Abstract
This study is concerned with the stability of liquid crystal forming emulsifier with localized depend on change of pH using liquid crystal forming agent of advanced company. The liquid crystal emulsifying agent was localized using Sugar Crystal-LC (bio-tech Co., Ltd., Korea), and comparative samples were measured by using Nikkomulese-LC (Nikko Camicarls, Japan) and Alacel-LC (Croda Camicarls, UK). Liquid crystal formation was confirmed microscopically to show the formation of liquid crystal structure at acidic (pH=4.2), neutral (pH=7.0) and alkaline (pH=11.7). The particles of the liquid crystal were observed with a polarizing microscope according to the stirring speed. The stirring time was all the same for 3 minutes with a homo-mixer, and the stirring speed was increased to 2500 rpm, 3500 rpm and 4500 rpm to observe the liquid crystal state. As a result, it was found that the Korean surfactant was more stable and clear liquid crystal structure was formed than the two foreign acids. In the case of the UK in acid zone, the emulsion particle size was uniform and unstable. In the case of Japanese surfactant, it has similar structure and performance to those of localized Korean. It was found that Korean surfactant had superior emulsifying performance in acid zone compared with foreign products. It is possible to develop various formulations such as liquid crystal cream, lotion, eye cream, etc. using Sugar Crystal-LC emulsifier as an application cosmetic field, and it is expected that it can be widely applied as emulsifying technology for skin care external application in the pharmaceutical industry and the pharmaceutical industry as well as the cosmetics industry.
Keywords
liquid crystalline structure; polarized microscopy; stability; emulsification; skin care cosmetics;
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Times Cited By KSCI : 6  (Citation Analysis)
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1 S. R. Hwang, J. O. Nam, B. J. Lee, W. H. Song, and C. S. Lee, Recent emulsion technology in cosmetics, Korean Society for Biotechnology and Bioengineering Journal, 27, 207-214 (2012).
2 I. Y. Kim, C. K. Zhoh, H. C. Ryu, Liquid crystalline technology of cosmetic industry and moisturizing effect of skin, J . Soc., Cosmet. Scientist Korea, 30(2), 279 (2004).
3 Kim, In-Young, Choi Wha-Sook, Lee So-Ra, Choi Seong-Ho, Self Assembly and Formation of Bi-continuous Cubic Liquid Crystalline Phase, J. of The Korean Oil Chemists' Soc., 31(3), 478-485 (2014).   DOI
4 Wanping Zhang, Lingyan Liu, Study on the formation and properties of liquid crystal emulsion in cosmetic, Journal of cosmetics, dermatological sciences and applications, 3, 139-144 (2013).   DOI
5 S. A. Lavaselli, C. I. Pedemonte, J. I. Mazon, G. J. Lillini, R. C. Pasquali, B. Riquelme, Rheological behavior of liquid-crystalline emulsion of topic application with econazole nitrate, Series on Biomechanics, 27(3-4), 34-38 (2012).
6 Krister Holmberg, Identification of lyotropic liquid crystalline mesophases, Handbook of applied surface and colloid chemistry, 299-301(2001).
7 M.J. Choi, Y.M. Lee, B. S. Jin, Study on the liquid crystal and stability in w/oemulsion systems using beeswax and Silicone surfactants, J. of Korean Oil Chemists', 21(4), 279-288 (2004).
8 Park, In Ae and An, In Sook, The study for the emulsifier and the formation of liquid crystal, Korean Esthetics and Cosmetology, 5(22), 119-128 (2007).
9 M. Y. Hyun, Y. H. Lee, W. J. Oh, K. H. Yoo, K. Y. Park, M. N. Kim, C. K. Hong, and B. J. Kim, Effects of topical moisturizers on the skin of healthy full-term infants and toddlers, J. Soc. Cosmet. Sci. Korea, 41(1), 63-71 (2015).   DOI
10 Kim, Bun-Hee / Bae, Kun-Hye, Formation of Essencial oil-Liquid Crystal by Solubilization, Korean Esthetics and Cosmetology, 3(3), 133-141 (2005).
11 K. Liu, D. Chen, A. Marcozzi, L. Zheng, J. Su, D. Pesce, W. Zajaczkowski, A. Kolbe,W. Pisula, K. Mullen, N. A. C., and A. Herrmann, Thermotropic liquid crystals from biomacromolecules, PNAS, 111(52), 18596-18600 (2014).   DOI
12 Ben J. Boyd, Darryl V. Whittaker, Shui-Mei Khoo, Greg Davey, Lyotropic liquid crystalline phases formed from glycerate, surfactants as sustained release drug delivery systems, International Journal of Pharmaceutics, 309, 218-226 (2006).   DOI
13 E. Sepulveda, D. O. Kildsig, E. S. Ghaly, Relationship between internal phase volume and emulsion stability: the cetyl alcohol/stearyl alcohol system, Pharmaceutical Development and Technology, 8(3), 263-275 (2003).   DOI
14 M. C. Kim, C .S. Lee, and H. K. Park, Emulsion stability of water/oil emulsified fuel by associated with emulsifiers, J. of The Korean Oil Chemists' Soc., 25(3), 395-403 (2008).
15 M. J. Lee, N. H. Jeong, B. S. Jang, Preparation and Properties of Soybean Lecithin Liposome using Supercritical Reverse Phase Evaporation Method, J. of The Korean Oil Chemists' Soc., 27(4), 391-398 (2010).
16 C. K. Zhoh, K. Y. Lee, D. N. Kim, The influences of fatty alcohol and fatty acid on rheological properties of O/W emulsion, J. Soc. Cosmet. Scientists Korea, 35(2), 103-110 (2009).
17 W. Zhang, L. Liu, Study on the Formation and properties of liquid crystal emulsion in cosmetic, Journal of Cosmetics, Dermatological Sciences and Applications, 3, 139-144 (2013).   DOI
18 N. Krog, Structures of emulsifier-water mesophases related to emulsion stability, European journal of lipid science and technology, 77(7), 267-271 (1975).