• Title/Summary/Keyword: 유전자 매개변수

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A Study on Acceptance of Blockchain-Based Genetic Information Platform (블록체인 기반 유전자분석 정보플랫폼의 수용에 대한 연구)

  • In Seon Choi;Dong Chan Park;Doo Hee Chung
    • Information Systems Review
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    • v.23 no.3
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    • pp.97-125
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    • 2021
  • Blockchain is a core technology to solve personal information leakage and data management issues, which are limitations of existing Genomic Sequencing services. Due to continuous cost reduction and deregulation, the market size of Genomic Sequencing has been increasing, also the potential of services is expected to increase when Blockchain's security and connectivity are combined. We created our research model by combining the Technology Acceptance Model (TAM) and the Innovation Resistance Theory also analyzed the factors affecting the acceptance intention and innovation resistance of the Blockchain Based Genomic Sequencing Information Platform. A survey was conducted on 150 potential users of Blockchain and Genomic Sequencing services. The analysis was conducted by setting the four Blockchain variables: Security, transparency, availability, and diversity). Also, we set the Perceived Usefulness, Perceived risk, and Perceived Complexity for Technology Acceptance and Innovation Resistance variables and analyzed the effect of the characteristics of the Blockchain on acceptance intention and innovation resistance through these variables. Through this analysis, key variables that need to be considered important to reduce resistance and increase acceptance intention could be identified. This study presents innovation factors that should be considered in companies preparing a new Blockchain Based Genomic Sequencing Information Platform.

The Effects of Time Scale Variation on The Runoff Calculation of TOPMODEL (TOPMODEL 유출계산에서 시간 스케일에 대한 영향 분석)

  • Kim, Kyung-Hyun;Lee, Hak-Su;Kim, Won;Jung, Sung-Won;Kim, Sang-Hyun
    • Journal of Korea Water Resources Association
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    • v.35 no.2
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    • pp.125-136
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    • 2002
  • The effects of the temporal scale of input hydrological data on runoff simulation have been studied using hydrological data with various time scales. TOPMODEL has been employed to explores these effects. The Genetic a1gorithm was used to calibrate model Parameters. The results of sensitivity analysis in various time scales provide the insight of parameter space for TOPMODEL operation of different time scale. The variation of temporal scale of input hydrological data appeared to have significant impacts on the model efficiency, average water table depth, the ratio of the surface runoff to the total runoff and the calibrated parameters. Generally, the longer the time scale, the more surface runoff and the less average water table death were calculated. It is found that the impact of lime scale to runoff simulation results from the structure of TOPMODEL and the hydrographic morphology.

Dynamic Traffic Assignment Using Genetic Algorithm (유전자 알고리즘을 이용한 동적통행배정에 관한 연구)

  • Park, Kyung-Chul;Park, Chang-Ho;Chon, Kyung-Soo;Rhee, Sung-Mo
    • Journal of Korean Society for Geospatial Information Science
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    • v.8 no.1 s.15
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    • pp.51-63
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    • 2000
  • Dynamic traffic assignment(DTA) has been a topic of substantial research during the past decade. While DTA is gradually maturing, many aspects of DTA still need improvement, especially regarding its formulation and solution algerian Recently, with its promise for In(Intelligent Transportation System) and GIS(Geographic Information System) applications, DTA have received increasing attention. This potential also implies higher requirement for DTA modeling, especially regarding its solution efficiency for real-time implementation. But DTA have many mathematical difficulties in searching process due to the complexity of spatial and temporal variables. Although many solution algorithms have been studied, conventional methods cannot iud the solution in case that objective function or constraints is not convex. In this paper, the genetic algorithm to find the solution of DTA is applied and the Merchant-Nemhauser model is used as DTA model because it has a nonconvex constraint set. To handle the nonconvex constraint set the GENOCOP III system which is a kind of the genetic algorithm is used in this study. Results for the sample network have been compared with the results of conventional method.

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Automatic Acquisition of Fuzzy Reasoning Rules for Double Inverted Pendulum Controller Using Modified DNA coding method (변형된 DNA 코딩 방법을 이용한 이중 도립진자 제어기의 퍼지 추론규칙 자동획득)

  • Yun, Sung-Yong;Han, Il-Suk;Oh, Sung-Kwun;Ahn, Tea-Chon
    • Proceedings of the KIEE Conference
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    • 1999.11c
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    • pp.576-578
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    • 1999
  • 본 논문에서는 생물학적인 DNA와 유전자 알고리즘의 진화 메커니즘에 근거를 둔 DNA 코딩방법을 변형하여 새로운 DNA 코딩 방법을 제안한다. 이 방법은 기존의 DNA 코딩 방법이 DNA 유전자의 Redundancy와 Over-lapping 성질 때문에 갖고 있는 DNA 자체의 특성인 염색체의 길이를 자유자재로 변화시킬 수 있는 코딩 기술에 진화단계에서 변형을 가할 수 있는 새로운 유전자 알고리즘을 추가하여, 초기에 국소해로 접근하는 일반적인 유전자 알고리즘의 위험 부담률을 줄이고, 전역 해로의 접근 가능성을 높이는 방법을 제시한다. 또한. 이 변형된 DNA 코딩 방법의 가능성을 입증하기 위하여 시스템 제어에 필요한 지식을 표현하는 적당한 퍼지 규칙을 후건부의 매개변수의 동조만을 통하여 획득하고, 이 규칙에 변형된 DNA 코딩 방법을 적용하여 최적화 된 새로운 퍼지규칙 획득 알고리즘을 개발한다. 제안된 알고리즘을 이용한 퍼지 제어기를 설계하고. 이 제어기의 유용성을 입증하기 위하여 병렬형 이중 도립진자 시스템에 적용하여 시뮬레이션을 실행한 결과 효과적으로 퍼지규칙을 획득하고 제어함을 알 수 있다.

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Optimization of direct design system of semi-rigid steel frames using advanced analysis and genetic algorithm (고등해석과 유전자 알고리즘을 이용한 반강접 강뼈대 구조물의 직접설계시스템의 최적화)

  • Choi, Se Hyu
    • Journal of Korean Society of Steel Construction
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    • v.18 no.6
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    • pp.707-716
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    • 2006
  • The optimization of the direct design system of semi-rigid steel frames using advanced analysis and genetic algorithm was presented. Advanced analysis can predict the combined nonlinear effects of connection, geometry, and material on the behavior and strength of semi-rigid frames. Geometric nonlinearity was determined using stability functions. On the other hand, material nonlinearity was determined using the Column Research Council (CRC) tangent modulus and parabolic function. The Kishi-Chen power model was used to describe the nonlinear behavior of semi-rigid connections. The genetic algorithm was used as the optimization technique. The objective function was assumed as the weight of the steel frame, with the constraint functions accounting for load-carrying capacities, deflections, inter-story drifts and ductility requirement. Member sizes determined by the proposed method were compared with those derived using the conventional method.

Acquisition of Fuzzy Rules Using DNA Coding Method (DNA Coding Method를 이용한 퍼지 규칙의 획득)

  • 윤성용;박종규;오성권;안태천
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 1998.03a
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    • pp.16-19
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    • 1998
  • 본 논문에서는 생물학적인 DNA와 인위적인 DNA의 개발 메커니즘에 근거를 둔 새로운 DNA coding mithod를 소개한다. 이 방법은 DNA 유전자의 Redundancy 성질과 Over-lapping 성질을 분석하여 구성한 알고리즘으로, DNA 자체의 특성 때문에 염색체의 길이를 자유자재로 변화시킬 수 있는 장점을 가지고 있다. 즉 삽입과 삭제의 과정을 쉽게 처리할 수 있다. 따라서 본 연구에서는 이 DNA coding method를 사용하여 시스템 제어에 필요한 지식을 표현하는 적당한 퍼지규칙을, 전건부와 후건부의 구조 및 매개변수 동조를 통하여, 획득하고, 이 규칙을 새로운 유전자 알고리즘을 이용하여 최적화 시킬 수 있는 새로운 퍼지규칙 획득 알고리즘을 개발한다. 이 방법의 유용성을 입증하기 위하여 물탱크 시스템에 적용한 결과 효과적으로 퍼지규칙을 획득한다.

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A study on Comparison of the Palate Methods for Multi-objective optimization ptoblem (다중 최적화 문제에서 파레토 방법들 비교 연구)

  • Ko, Young-Sang
    • Proceedings of the KIEE Conference
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    • 2003.07d
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    • pp.2639-2641
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    • 2003
  • 유전자 알고리즘은 다윈의 자연선택설과 유전자의 진화 개념을 이용한 적응 탐색 알고리즘으로 적용하고자 하는 문제의 매개 변수를 유전자와 비슷한 데이터 구조로 부호화하고, 유전 연산자를 이용하여 문제의 해답을 찾는 알고리즘이다. 최근 유전자 알고리즘은 이러한 복수개의 목적 함수를 최적화 하기 위한 다중 최적화 문제를 위한 최적화 기술로서의 관심이 크게 다루어지고 있으며 전송 문제, 생산 공정 문제 계획 등과 같은 다목적 함수를 다루는 많은 응용 부분에 대해 적용되고 있다. 본 논문에서는 기본적인 다중 목적 함수용 예와 Gen과 Kim이 제안한 네트워크 신뢰도를 고려한 연결 비용과 메시지 지연을 고려한 이중 구속 통신망 설계 문제를 가지고 가중치 합과 여러 가지 파레토 방법들을 비교하고 연구 검토 하고자 한다.

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Derivation of Probable Rainfall Intensity Formula Using Genetic Algorithm (유전자 알고리즘을 이용한 확률강우강도식의 산정)

  • La, Chang-Jin;Kim, Joong-Hoon;Lee, Eun-Tai;Ahn, Won-Sik
    • Journal of the Korean Society of Hazard Mitigation
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    • v.1 no.1 s.1
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    • pp.103-115
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    • 2001
  • The current procedure to design hydraulic structures in a small basin area is to estimate the probable rainfall depth using rainfall intensity formula. The estimation of probable rainfall depth has many uncertainties inherent with it. However, it has been inevitable to simplify the nonlinearity if the rainfall in practice. This study attend to address a method which can model the nonlinearity in order to derive better rainfall intensity formula for the estimation of probable rainfall depth. The results show that genetic algorithm is more reliable and accurate than trial-and-error method or nonlinear programming technique(Powell's method) in the derivation of the rainfall intensity formula.

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Derivation of Plotting Position Formulas Considering the Coefficients of Skewness for the GEV Distribution (왜곡도 계수를 고려한 GEV 분포의 도시위치공식 유도)

  • Kim, Soo-Young;Heo, Jun-Haeng;Choi, Min-Young
    • Journal of Korea Water Resources Association
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    • v.44 no.2
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    • pp.85-96
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    • 2011
  • Probability plotting position is generally used for the graphical analysis of the annual maximum quantile and the estimation of exceedance probability to display the fitness between sample and an appropriate probability distribution. In addition, it is used to apply a specific goodness of fit test. Plotting position formula to define the probability plotting position has been studied in many researches. Especially, the GEV distribution which is an important probability distribution to analyze the frequency of hydrologic data was popular. In this study, the theoretical reduced variates are derived using the mean value of order statistics to derived an appropriate plotting position formula for the GEV distribution. In addition, various forms of plotting position formula considering various sample sizes and coefficients of skewness related with shape parameters are applied. The parameters of plotting position formulas are estimated using the genetic algorithm. The accuracy of derived plotting position formula is estimated by the errors between the theoretical reduced variates and those by various plotting position formulas including the derived ones in this study. As a result, the errors by derived plotting position formula is the smallest at the range of shape parameter with -0.25~0.10.

Calibration of the Ridge Regression Model with the Genetic Algorithm:Study on the Regional Flood Frequency Analysis (유전알고리즘을 이용한 능형회귀모형의 검정 : 빈도별 홍수량의 지역분석을 대상으로)

  • Seong, Gi-Won
    • Journal of Korea Water Resources Association
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    • v.31 no.1
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    • pp.59-69
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    • 1998
  • A regression model with basin physiographic characteristics as independent variables was calibrated for regional flood frequency analysis. In case that high correlations existing among the independent variables the ridge regression has been known to have capability of overcoming the problems of multicollinearity. To optimize the ridge regression model the cost function including regularization parameter must be minimized. In this research the genetic algorithm was applied on this optimization problem. The genetic algorithm is a stochastic search method that mimic the metaphor of natural biological heredity. Using this method the regression model could have optimized and stable weights of variables.

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