• Korean Journal of Psychosomatic Medicine
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• v.4 no.1
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• pp.37-43
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• 1996

This study was designed to investigate the relationship between changes in manic symptoms and in thyroid hormone level in manic patients. Thyroid hormones(T3, T4) and TSH were measured, and Young's Mania Rating Scale(YMRS) was scored in twenty manic inpatients, at the time of admission and 6 weeks later. Mean value of T3 was slightly increased(increase : 9, decrease : 11). Mean value of T4 was fairly decreased(increase 4, decrease 16), while that of TSH was increased(increase 14, decrease : 6). Mean total score of YMRS was fairly decreased and mean values of each eleven subscales were decreased. Subjects were classified as increased, decreased and unchanged group for each thyroid hormones. for T3, there was statistically significant differences in YMRS subscale of 6(speech : speed/amount), 7(language, thought disturbance) and 10(appereance) between 3 groups. With the above results, the changes of manic symptom during the course of illness could probably be indicated by the thyroid hormon change, and manic symptoms could be classified as subtypes in terms of thyroid hormone change.

• The Journal of the Korea Contents Association
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• v.14 no.7
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• pp.376-385
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• 2014

This study is aimed to ascertain the hospital information inquired by medical consumers and to propose the consumer-oriented marketing direction of the medical institutions. In the pursuit of this purpose, we examined about the purpose of the hospital information usage by medical consumers, the contents of the inquired information, the method of the information acquisition and the practicability of the acquired information. As the result of this study, more than 90% out of the purposes of hospital information usage is for the practical use of the medical institution, especially, 58.7% is for the effective selection of the medical institutions when consumer's family or relatives are sick. Regardless of the purpose of hospital information usage, for the contents of the inquired information, more than 50% responded with the medical institution facility, the specific contents about the professional field and the special field. The most favorite method to acquire the information according to the purpose of hospital information usage is through 'Acquaintance' which are the highest rate, more than 50% and the level of 24~28% are through 'Internet'. And the practicability of the acquired information was fairly low like the result as 4.8% for the selection of the medical institutions when consumer's family or relatives are sick and 0.5% for the health counseling or the medical check-up.

• Proceedings of the Korea Contents Association Conference
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• 2009.05a
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• pp.244-249
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• 2009

At the 21th century management environment with the emotion and creativity, as design has recognized the core element of management strategy, the combination of design and management, design management, has been increased the importance worldwidely. In the rapid changing enterprise environment, the small or venture enterprises in flexible management environment than the large enterprise have advantage on management process. The design management has created the various field of knowledge in the integrated solution, the integrated approach methods of management are the effective operative process in the importance of design management. As CEOs in small/venture enterprise take part in the innovation of design management, a specialistes in recognition of specificity and design management are defined and created the design management process through the enterprise resource planning programs. With the understanding on the above situation, the purpose of this study is to suggest the design is strategically applied in the management level of Daejeon region small/venture enterprises and the recognition of design management as a strengthen the competitiveness.

• The Korea Journal of Herbology
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• v.31 no.1
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• pp.7-15
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• 2016

Objectives : Polygalae Radix (POL) has an ameliorating effect on learning and memory impairment caused by cerebral hypoperfusion. In regard to POL's action mechanism, this study was carried out to investigate the effects of POL on oxidative damage and neuronal apoptosis induced by cerebral hypoperfusion in rats.Methods : The cerebral hypoperfusion was induced by permanent bilateral common carotid artery occlusion (pBCAO) in Sprague-Dawley rats. POL was administered orally once a day (130 mg/kg of water-extract) for 28 days starting at 4 weeks after the pBCAO. Superoxide dismutase (SOD) activities and malondialdehyde (MDA) levels in the brain tissue were measured using ELISA method. Expressions of 4-hydroxynonenal (4HNE) and 8-hydroxy-2'- deoxyguanosine (8-OHdG) were observed using immunohistochemistry. In addition, neuronal apoptosis was evaluated with Cresyl violet staining, TUNEL labeling, and immunohistochemistry against Bax and caspase-3.Results : POL treatment significantly increased SOD activities and significantly reduced MDA levels in the cerebral cortex. The up-regulations of 4HNE and 8-OHdG expression caused by pBCAO in the CA1 of hippocampus were significantly attenuated by POL treatment. POL treatment also restored the reduction of CA1 thickness and CA1 neurons caused by pBCAO and significantly attenuated the apoptotic markers including TUNEL-positive cells, Bax, and caspase-3 expression in the CA1 of hippocampus.Conclusions : The results show that POL attenuated the oxidative damage in brain tissue and neuronal apoptosis in the hippocampus caused by the cerebral hypoperfusion. It suggests that POL can be a beneficial medicinal herb to treat the brain diseases related to cerebral hypoperfusion.

• Journal of the Korea Convergence Society
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• v.10 no.12
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• pp.81-91
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• 2019

This study empirically examines the relationship between the characteristics of a company and its performance through open innovation. It was intended to accept open innovation as a strategic means to overcome various situations in which companies faced and to understand it as a process of generating corporate performance. In various situations, companies must overcome environmental and internal factors. As an environmental factor, the dynamics of the market and the dynamics of technology allow for the adoption of open innovation, which in turn becomes a strategic tool for generating results. In addition, the internal environment of the company should strengthen the organization's capacity considering the characteristics of the company. In order to reinforce entrepreneurial orientation, openness of organizational culture, delegation and R & D capabilities, which are internal characteristics of the company, open innovation has a positive effect on the performance of the company. In overcoming the environment given to the company, open innovation was found to be an important medium for generating various results for the company. For this study, we conducted a structured questionnaire survey on 176 Korean companies. This study suggests that open innovation is strategically accepted and understood as a management strategic philosophy in order to overcome the environment in which a company is faced and generate results.

• The Journal of Korean Medicine
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• v.29 no.3
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• pp.144-154
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• 2008

Objectives: Osteoporosis is one of the most common metabolic bone disorders in the menopausal stage, a disease signified by decrease of bone mass. The purpose of this study was to learn how Lycii Fructus influences SD rats with osteoporosis caused by the removal of the ovaries. Methods: After the removal of the ovaries from 24 female Sprague-Dawley rats, they were divided into a normal group, a control group, and a Lycii Fructus (25mg/100g) administration group. After 8 weeks, the rats were sacrificed and their weights, albumin, AST, ALT, ALP, total-cholesterol, triglyceride, P, Ca, T4, E2, weight of a femur, ash content of the tibia, and area and thickness of trabecular bone were measured. Results: Regarding the density of ALT, ALP, and estradiol from serum, the Lycii Fructus group was significantly decreased compared to the control group, and the density of phosphorous and calcium also decreased slightly. Moreover, albumin, triglyceride, and T4 showed an increasing propensity, but AST and total-cholesterol showed a decreasing propensity, but not significant. Regarding the variation of bone, femur weight and ash content of tibia, the Lycii Fructus group was increased compared to the control group but significance wasn't shown. The Lycii Fructus group increased significantly over the control group in area and thickness of trabecular bone and osteoclast number. Conclusions: From the results of the above study, Lycii Fructus should be effective for osteoporosis treatment and prevention.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.3
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• pp.173-179
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• 2016

Purpose: This study is to help assist in the management of optical shops by using the importance sequence of optical shop selection attributes, which is related to the consumer's selection method of consumer, and by using the importance sequence of optical shop information sources which is related to a route for optical shop selection. Methods: Customer surveys were conducted from March 10 to March 31, 2015 targeting customers who have visited an optical shop in Seoul and Northern Gyeonggi-do regions. The analys method was descriptive statistics and data were analyzed by utilizing SPSS v.10.0 statistical package program. Results: The highest ranking five attributes among the importance of optical shop selection are "friendliness and politeness of staff", "cleanliness of an optical shop", "quick resolution of customer's complaints by staff", "eyes examination and glasses dispensing skill of staff", "customer's complaints and claims handling". The lowest ranking five attributes among the importance of optical shop selection are "provide free gifts", "scale or size of an optical shop", "opening time and closing time", "convenient parking facilities", "favorable countenance of staff". The two highestr ranking criteria among the importance of optical shop information sources are "previous utilization experience", "recommendation by a relative, a friend and a family etc". The two lowest ranking criteria among the importance of optical shop information sources are "advertisement" and "spatial exterior view of optical shop". Conclusions: It is shown that the important thing in management of an optical shop is an inner caliber like ability of ophthalmic optician, interaction with customers, and previous utilization experience rather than external factors like advertisement, exterior view, and bonus gift.

• Journal of the Korea Convergence Society
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• v.9 no.9
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• pp.245-252
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• 2018

This study interprets the corporate social responsibility and its management through analysis of philosophical view of Mozi(墨子). Mozi was a chinese philosopher during the Hundred Schools of Thought period. He advocated Universal love(兼愛), which stresses that people should care for everyone equally. This principle is in accord with the sustainable management strategy for global market environments. The realization of the value that the company pursues in the rapid growth of such enterprises is an important issue. The pursuit of corporate value in its own interest under the rapidly changing business environment is perceived very negative. And it has demanded a different philosophy as a new management philosophy. The philosophical strategies of these companies were centered around the core philosophy of the ancient Chinese philosopher, Mozi. It is not merely an outcome approach as the act or moral principle but the inner motive to love each other and the principle of sharing the profits of each other. In order to pursue the sustainable value of the enterprise, We would like to suggest a way to pursue the existing absolute value, and to suggest a philosophical strategy based on the philosophy of Mozi.

• The Journal of the Korea Contents Association
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• v.11 no.10
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• pp.405-415
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• 2011

The primary purpose of this paper is to identify the influencing factors on the new products adoption between countries and generations. For this purpose, a research is developed based on the relevant literature reviews. Data have been collected from 524 persons and were tested by t-test and various statistical methods. The results of this empirical study are summarized as follows. In the cultural factors, the groupism has high discretion in China old generation. The materialism and shopping preference have high discretion in two young generations. There is no difference between the two groups in the distance of power. In innovativeness of personality, Korea and China young generation have high discretion. Innovativeness has high discretion in Korea and China youngs. Cognition and sensory innovativeness are has low discretion in Korea old. In the social risk perception, physiological, functional general and financial risk has high discretion in China old. In risk reducing behavior, the normative taking level and ad, new product adoption has high discretion in Korea and China youngs. But, the influence of others has high discretion in China old generation. The safety and brand reputation are no influences. The findings have a several marketing strategies in generation and countries.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6905-6916
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• 2015

The primary purpose of this paper is to find out the environmental regulation in our global society with complex system concept. After the industrial revolution, there were working toward solving various problems while there has been an industry advancement. But, there are various issues that a simple international trade or economic technologic levels were not solved. The evolution of technologies through complex systemic thought are not accidental issues. These issues build and provide a predictable technology innovation that system was emergent a new order. With complex systemic thought, the earth that was facing environmental problems was in the phrase edge of chose. These conditions played the trigger role for the solving various problems in environmental regulations but they don't get along well together. There were no causal relationship between structural elements. This paper describes an emergence of new order through these interactions in environmental regulation. These environmental regulations make desperate efforts not only public sectors but also private or/and firms that make an emergence of new order with the critical point reached. Also, we provide the understanding base an environmental regulation with new order for uncertainty.