• Journal of the Korean Society of Food Science and Nutrition
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• v.40 no.9
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• pp.1201-1207
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• 2011

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been proposed as a potent tool to trigger apoptosis in cancer therapy. However, as many types of cancer cells remain resistant towards TRAIL-induced cytotoxicity, several combined therapy approaches aimed to sensitize cells to TRAIL have been developed. Genistein, a natural isoflavonoid phytoestrogen, has been shown to have anticancer activity by inducing cell cycle arrest at G2M phase as well as apoptosis in various cancer cell lines. In the present study, we showed that treatment with TRAIL in combination with subtoxic concentrations of genistein sensitized U937 human leukemia cells to TRAIL-mediated apoptosis. Combined treatment with genistein and TRAIL effectively activated caspases through Bid truncation (tBid) and down-regulation of cellular caspase-8 (FLICE)-like inhibitory proteinL ($cFLIP_L$). However, the apoptotic effects of co-treatment with genistein and TRAIL were significantly inhibited by specific caspase inhibitors, which demonstrates the important role of caspases in apoptosis induced by genistein and TRAIL. Overall, our results indicate that genistein can potentiate TRAIL-induced apoptosis through down-regulation of $cFLIP_L$ and up-regulation of pro-apoptotic tBid proteins.

• Culinary science and hospitality research
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• v.17 no.5
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• pp.74-91
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• 2011

The purpose of this study is to investigate the efficiency of a government-supported project developed to improve the quality and hygiene levels of food, service, and restaurant facilities for foreign customers in Chungnam province. Data was collected from 53 restaurant owners and restaurant managers. This study empirically analyzes and presents a mode with key factors influencing transfer of training and training satisfaction. Multiple regression analysis methods were used to test the relationships among four factors for transfer of training, training satisfaction, and retraining intentions. There are three main findings. First, teaching methods and relevance factors had a significant effect on transfer, but instructor and education environment factors did not. Second, the teaching methods, instructor and education environment factors had a direct influence on training satisfaction, but the relevance factor didn't. Third, transfer and satisfaction both were influenced significantly by retraining. Based on the findings of this study, a trainer, designing training curriculum for a production environment, should emphasize the role of the trainer and focus on learning tools. Finally, a thorough learning design is needed for learner's satisfaction.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.10
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• pp.1277-1286
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• 2018

In this paper, we provide flexible scalability of computing resources in cloud environment and Apache Hadoop based cloud environment for analysis of public medical information big data. In fact, it includes the ability to quickly and flexibly extend storage, memory, and other resources in a situation where log data accumulates or grows over time. In addition, when real-time analysis of accumulated unstructured log data is required, the system adopts Hadoop-based analysis module to overcome the processing limit of existing analysis tools. Therefore, it provides a function to perform parallel distributed processing of a large amount of log data quickly and reliably. Perform frequency analysis and chi-square test for big data analysis. In addition, multivariate logistic regression analysis of significance level 0.05 and multivariate logistic regression analysis of meaningful variables (p<0.05) were performed. Multivariate logistic regression analysis was performed for each model 3.

• The Journal of the Korea Contents Association
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• v.21 no.9
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• pp.528-542
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• 2021

This study aims to examine the attitudes toward online advertisement targeting YouTube content users and to present implications for the direction and regulation of personal media broadcasting advertisement. The study used the data from 'Awareness of On-line Ads and Blocking Tools' conducted by the Korea Press Foundation in 2020. For the statistical analysis, correspondent analysis was employed. The main results followed as: women tended to perceive more discomfort about the ads before the start of the content compared to men, and women in twenties perceived the highest discomfort with intermediate advertisement. Second, respondents who watch more YouTube contents tended to accept more ads to use contents for free. Third, respondents who are willing to use the advertisement blocking service were most aware of the inconvenience of advertisements before starting of YouTube contents. Although users are aware of the inconvenience, the use of advertisement blocking service has not yet been found to be generalized. However, the use of ad blocking service is expected to increase gradually. It would be expected that efforts to regulate advertisement to reduce discomfort about advertisement among users are also required.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.5
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• pp.465-474
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• 2021

This study investigated knowledge about the human papillomavirus (HPV), attitudes toward HPV vaccination, and intention to receive HPV vaccination among marriage-immigrant women, and identified factors associated with intention to receive HPV vaccination. The subjects of this study were 136 marriage-immigrant women in J Province. Data were collected from September 28 to December 21, 2017, and analyzed using SPSS for Windows version 24.0. The participants' knowledge of HPV was low (mean score, 2.74) and their attitude towards HPV vaccination was positive (mean score, 36.66). The factors affecting the intention to take the HPV vaccination included Vietnamese nationality (odds ratio [OR]=2.899, p=.048), desire for education about the HPV vaccine (OR=5.967, p<.001), and a positive attitude towards HPV vaccination (OR=1.083, p=.034). Therefore, educational programs about HPV vaccination targeting marriage-immigrant women are needed. It is also necessary to provide accurate information about the HPV vaccination using various methods, at health care facilities and through mass media.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.594-603
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• 2019

This purpose of this study is for an Airline company to discover and utilize new knowledge because knowledge and information are considered core tools for achieving high performance and competitive advantage, and achieving high performance and competitive advantage will surely determine the long-term survival of airline companies. Therefore, this study aims to reveal the causal relationships among different types of organizational culture, the knowledge sharing activities and the effectiveness of organizational work by airline members from a holistic viewpoint. The results of analysis are as follows. First, when examining the effects of the organizational culture types of airline members on knowledge sharing, a creative innovation culture, a relational group culture and a hierarchical orientation culture all showed positive effects on knowledge sharing. Second, the knowledge sharing by airline members showed a significant positive effect on the effectiveness of organizational work. Third, the creative innovation culture, the relational group culture and the hierarchical orientation culture all showed positive effects on the effectiveness of organizational work. Fourth, knowledge sharing did not have a mediating effect on the relationship between organizational culture and the effectiveness of organizational work.

• 한국노년학
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• v.36 no.3
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• pp.633-648
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• 2016

This study focuses on the sleep pattern of the elderly people living in the community and its relationship to the occurrences of the depression and deterioration of the cognitive function. Our primary data is the raw data gathered by the Korean Ministry of Health and Welfare in 2008 in the National Senior Living Conditions and Well-being Needs Assessment Survey. The survey contained data from 12,087 people over 65 years of age living in the community. We have used the secondary data analysis method on this raw data to see if there exists correlation between age, gender, soundness of the sleep, total sleep time and the depression and the cognitive difficulties. Our study finds that the older a person is, the more trouble she has in sleeping. It also shows that too much sleep (in excess of 9 hours) and too little sleep (less than 6 hours) can both be linked to more occurrence of depression. Lack of restful sleep could also be linked to more frequent occurrence of depression and cognitive difficulties. Changes in the sleep pattern is not always pathological in elderly people. However, our study shows that it is important the primary health-care givers understand the role of sleep in elderly person's daily life. They should examine the elderly person's sleep pattern focusing on the quantity and the quality of sleep and develop programs suited for individuals to prevent and intervene sleep disorder.

• Journal of Korea Water Resources Association
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• v.55 no.1
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• pp.71-84
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• 2022

The objective of this study is to develop a two-dimensional (2D) flood model that can perform accurate flood analysis with simple input data. The 2D flood inundation models currently used to create flood forecast maps require complex input data and grid generation tools. This sometimes requires a lot of time and effort for flood modeling, and there may be difficulties in constructing input data depending on the situation. In order to compensate for these shortcomings, in this study, a grid-based model that can derive accurate and rapid flood analysis by reflecting correct topography as simple input data was developed. The calculation efficiency was improved by extending the existing 2×2 sub-grid model to a 5×5. In order to examine the accuracy and applicability of the model, it was applied to the Gamcheon Basin where both urban and river flooding occurred due to Typhoon Rusa. For efficient flood analysis according to user's selection, flood wave propagation patterns, accuracy and execution time according to grid size and number of sub-grids were investigated. The developed model is expected to be highly useful for flood disaster mapping as it can present the results of flooding analysis for various situations, from the flood inundation map showing accurate flooding to the flood risk map showing only approximate flooding.

• The Journal of the Convergence on Culture Technology
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• v.8 no.2
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• pp.367-372
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• 2022

With the recent advent of the New Normal era, realistic technologies and non-contact technologies are receiving social attention. However, the hair styling field focuses on the direction of the hair itself, individual movements, and modeling, focusing on hair simulation. In order to create an improved practice environment and demand of the times, this study proposed a non-contact hair styling VR system. In the theoretical review, we studied the existing cases of hair cut research. Existing haircut-related research tend to be mainly focused on force-based feedback. Research on the interactive haircut work in the virtual environment as addressed in this paper has not been done yet. VR controllers capable of finger tracking the movements necessary for beauty enable selection, cutting, and rotation of beauty tools, and built a non-contact collaboration environment. As a result, we conducted two experiments for interactive hair cutting in VR. First, it is a haircut operation for synchronization using finger tracking and holding hook animation. We made position correction for accurate motion. Second, it is a real-time interactive cutting operation in a multi-user virtual collaboration environment. This made it possible for instructors and learners to communicate with each other through VR HMD built-in microphones and Photon Voice in non-contact situations.

• The Journal of the Convergence on Culture Technology
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• v.7 no.2
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• pp.85-95
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• 2021

Currently, we stand between computers as creative tools and computers as creators. A new genre of movies, which can be called a post-cinema situation, is emerging. This paper aims to diagnose the possibility of the emergence of AI cinema. To confirm the possibility of AI cinema, it was examined through a case study whether the creation of a story, narrative, image, and sound, which are necessary conditions for film creation, is possible by artificial intelligence. First, we checked the visual creation of AI painting algorithms Obvious, GAN, and CAN. Second, AI music has already entered the distribution stage in the market in cooperation with humans. Third, AI can already complete drama scripts, and automatic scenario creation programs using big data are also gaining popularity. That said, we confirmed that the filmmaking requirements could be met with AI algorithms. From the perspective of Manovich's 'AI Genre Convention', web documentaries and desktop documentaries, typical trends post-cinema, can be said to be representative genres that can be expected as AI cinemas. The conditions for AI, web documentaries and desktop documentaries to exist are the same. This article suggests a new path for the media of the 4th Industrial Revolution era through research on AI as a creator of post-cinema.