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Expression of Cytochrome P450 Aromatase Genes during Sex Differentiation in Korean Rockfish, Sebastes schlegeli (조피볼락, Sebastes schlegeli의 성분화 기간 중 Cytochrome P450 Aromatase 유전자의 발현)

  • Lee, Chan-Hee;Kwon, Joon-Yeong
    • Development and Reproduction
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    • v.11 no.3
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    • pp.195-203
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    • 2007
  • Sex determination and sex differentiation are influenced by genotype in many gonochoristic fish. Cytochrome P450 aromatase (CYP19) is the terminal enzyme in steridogenic pathway that converts androgens into estrogens. In this study, partial fragments of aromatase genes (ovarian aromatase, P450aromA and brain aromatase, P450aromB) were cloned and sequenced in Korean rockfish (Sebastes schlegeli), and gene specific primers were designed based on their sequences. Using these primers, aromatase gene expression during sex differentiation was investigated by RT-PCR. Expression of these aromatase genes were detected both in the head and body parts at 35 dab (days after birth). The number of fish that expressed the aromatase genes decreased at 52 dab, implying down-regulation of these genes. However, these genes were expressed at 59 dab in almost all fish studied here. The expression patterns of both genes are similar throughout the investigated period except for 45 dab where the expression of P450aromB was detected in more fish than that of P450aromA both in the head and body parts. Timing of sex differentiation in this species has been shown to be at around $50{\sim}65$ dab by histological analysis. However, the results from this study suggest that sex differentiation of rockfish may take place $1{\sim}2$ weeks earlier than the period proposed previously. The results also suggest that the mechanism of sex differentiation in viviparous fish may be similar to that in oviparous fish in terms of the importance of aromatase action during the critical period.

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Analysis of Patent Trends on the CCUS Technologies (특허 정보 분석을 통한 CCUS 연구개발 동향 분석)

  • Kim, Jung-min;Kim, Seong-Yong;Bae, Junhee;Shinn, Young-Jae;Ahn, Eunyoung;Lee, Jae-Wook
    • Economic and Environmental Geology
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    • v.53 no.4
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    • pp.491-504
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    • 2020
  • Given the continued climate change and global warming, various technologies for greenhouse gas reduction were discussed worldwide as all 195 countries participated in the Paris Agreement on the reduction of greenhouse gases. The agreement was adopted at the 21st Conference of Parties to the UNFCCC (COP21), which was held in Paris, France, in December 2015, and it revealed that reducing CO2 is the most efficient method of greenhouse gas reduction. Accordingly, carbon capture/utilization/storage (CCUS) technology has been noted as a means of making practical contributions to CO2 reduction, and research and development (R&D) activities in many countries are active in the field of CCUS technology. Therefore, this study aims to provide a basis for CCUS R&D and strategic support measures by analyzing patent trends in technologies related to CCUS. The patent analysis collected a total of 10,137 patents in the United States, Korea, Japan, Europe, and China; the number of patents in the United States was the highest according to patent analysis by country. According to an analysis by technology, capture-related technology was high at 60%, but given the recent increase in technology related to utilization, technology demonstration, R&D, and policy support should be continued.

A Study on the Optimization of Edutainment Website design For Juvenile Users (에듀테인먼트 기반의 어린이 웹사이트 디자인에 관한 연구)

  • 손은미;임은정;이현주
    • Archives of design research
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    • v.15 no.1
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    • pp.143-152
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    • 2002
  • As the Internet has been a daily instrument of our lives, the numbers of Internet users are increasing rapidly. Especially, we have to pay special attention to about rapid increasing of juvenile users. In the 1990's, Kids are growing up literally surrounded by new technologies and mu1timedia experiences. For these kids, most of the techno1ologies that we adults find surprising or even incredible are a part of their everyday landscape, a fact of life. Currently, only few of research and discussion has gone into understanding this field. And most of these web sites, set importance on furnishing information only. So educational characters of web are not manifested fully as well as children soon get board with learning with Internet so that feel difficulties in searching and accepting information. At this point, we must try to develop educational sites Not only to show information but also to offer a rich and entertaining time for kids while providing playful teaming and increased technological fluency. Fer this purpose, Web site should be all about combining play with learning. Site navigation should be easy and the pages load quickly. The page download time is also being considerable, which could send kids withy mouse-fingers looking for entertainment elsewhere. Everything about the site must have a familiar feel, uses adequate colors to be satisfied with the juveniles. Multimedia can help the communications in the websites. To maximize the educational effect, technological research and continues invest are need, in addition to usability test.

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The Analysis on Patterns of Questions in Elementary School Science Textbooks under the 2007 Revised Curriculum (2007년 개정교육과정에 따른 초등 과학교과서에 제시된 발문의 유형 분석)

  • Choi, Yoon-mi;Lee, Hyeong Cheol
    • Journal of Science Education
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    • v.36 no.1
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    • pp.120-129
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    • 2012
  • The purpose of this study is to provide informations for developing next elementary school science textbooks and educational implications for a spot of science class through analyzing patterns of questions in the elementary school science textbooks under the 2007 revised curriculum. To get a meaningful results, the 2,446 questions extracted by operation definition from 3~6 grade science text books were analyzed by modified analysis frame work based on Blosser's classified system. The findings of this study were as follows: First, among 2,446 questions, the propositional pattern element had the highest rate, 49.2%, the appreciable pattern element had the lowest rate, 1.4%, of all pattern elements. Second, from the results of comparing patterns of questions in each grade's science textbook, as the grade went higher, the rate of the applicable and the divergent pattern element tended to increase, and that of the other elements tended to decrease. Third, as the results of comparing patterns of questions of 4 each field in elementary science textbooks, the energy field questions were the largest in number, followed by the substance field. The rate of the propositional pattern element was the highest of all question elements in common in each field. In the reproductive and the propositional pattern element, the energy and the substance field had a little higher rate than the other fields. On the other hand, in the applicable and the divergent pattern element, the earth and the life field had a little higher rate than the other fields.

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Combining Ability Analysis and Selection Effectiveness for Tolerance to Cold-Induced Sterility in Rice (벼 장해형 내냉성의 조합능력검정과 선발효과)

  • Huhn Pal, Moon;J. Neil, Rutger
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.33 no.4
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    • pp.412-419
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    • 1988
  • Cold-induced sterility is a problem of rice (Oryza sativa L.) production in temperate regions and high elevation tropics. The present study was conducted to measure combining ability, determine character associations. and to evaluate effectiveness of F$_2$selection for tolerance to this type of cold injury. The F$_1$, F$_2$, F$_3$ and reciprocal backcross F$_1$ populations of a nine-parent diallel were grown at Davis, California. a relatively cool location for rice. Additive genetic variance was predominant but some non -additive genetic variance existed for cold tolerance. Good general combining ability (GCA) was generally associated with the cold tolerant parents, 'M-201', and 'L-201', and poor GCA with the most susceptible parent. 7703008. Sterility was positively correlated with late heading. negatively with mature plant height. and negatively with spikelet number. Of the three agronomic characters, heading date had the greatest influence on sterility. Selection of F$_2$'s in seven crosses involving M-101, the most cold-tolerant parent, was effective for increasing cold tolerance. Realized heritability estimates for cold tolerance averaged 0.53, and observed selection response for cold-induced sterility averaged -9.4 percentage points.

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Analysis on Multi-Components of Neurotransmitter Release in Response to Light of Retinal ON-Type Bipolar Cells (망막 ON형 쌍극세포의 광응답에 따른 다중성분의 전달물질 방출에 관한 해석)

  • Jung, Nam-Chae
    • Journal of the Institute of Convergence Signal Processing
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    • v.14 no.4
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    • pp.222-230
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    • 2013
  • Retinal bipolar cells according to the light stimulus respond to potential slowly, emit neurotransmitter release(glutamine acid) to depend on membrane potential. In this paper, the several physiological information on neurotransmitter release mechanism in the presynaptic terminal of the ON-type bipolar cells are incorporated into the formula model. The source of fast components and slow components of neurotransmitter release was arranged in parallel, this model was able to reproduce the membrane potential and intracellular $Ca^{2+}$ concentration dependence of neurotransmitter release faithfully. In addition, because the fast releasable components of neurotransmitter was represented by the membrane potential dependence of trapezoid type, whereas the slow releasable components was represented by the membrane potential dependence of a bell type, $Ca^{2+}$ concentration rise in intracellular is suppressed by $Ca^{2+}$ buffer to reduce slow releasable components, it was confirmed that the membrane potential dependence of neurotransmitter release was characteristics of a trapezoid type. And, in the light response of ON type bipolar cell, the result of the simulation of the neurotransmitter release caused by the components of transient and persistent was that the start of light response occurred the fast release of neurotransmitter, it was confirmed that the transient component and persistent component of the light response occurred the slow release. It was confirmed that the later of persistent component of the light response occurred due to the continuous release by synaptic vesicle supplemented from the storage pool.

On the Requirements and Risk Management using QFD Methods for ACTD Programs (신개념기술시범(ACTD) 사업에서 QFD 기법을 이용한 요구사항 및 위험관리 방안에 관한 연구)

  • Lee, Tae-Hyung;Lee, Jae-Chon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.12B
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    • pp.1744-1751
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    • 2011
  • The concept of the advanced concept technology demonstration (ACTD) has previously been introduced in USA in order to make it possible to rapidly transfer advanced technologies developed in commercial sectors to develop weapon systems in the defense area. Since then in Korea several ACTD programs have been developed and being carried out However, there are few program management methods suitable for the characteristics of the ACTD programs, which requires stringent management of the program requirements and risks due to the radically shortened development time. In this paper such a problem has been addressed and as a solution approach the quality function deployment (QFD) method has been adopted, which is being served as a successful model in various areas such as manufacturing. The QFD method is used in our study to improve communication between various stakeholders involved in the ACTD programs and also to reduce risks related to requirements. Specifically we have developed the ACTD standard templates based on the QFD method and discussed how to use the developed templates. Finally, the application of the study result is demonstrated through the ACTD program of flight information demonstration system and also specific ways are suggested to use the standard templates, to manage requirements, and to reduce risks.

BPAF2.0: Extended Business Process Analytics Format for Mining Process-driven Social Networks (BPAF2.0: 프로세스기반 소셜 네트워크 마이닝을 위한 비즈니스 프로세스 분석로그 포맷의 확장 표준)

  • Jeon, Myung-Hoon;Ahn, Hyun;Kim, Kwang-Hoon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.12B
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    • pp.1509-1521
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    • 2011
  • WfMC, which is one of the international standardization organizations leading the business process and workflow technologies, has been officially released the BPAF1.0 that is a standard format to record process instances' event logs according as the business process intelligence mining technologies have recently issued in the business process and workflow literature. The business process mining technologies consist of two groups of algorithms and their analysis techniques; one is to rediscover flow-oriented process-intelligence, such as control-flow, data-flow, role-flow, and actor-flow intelligence, from process instances' event logs, and the other has something to do with rediscovering relation-oriented process-intelligence like process-driven social networks and process-driven affiliation networks from the event logs. The current standardized format of BPAF1.0 aims at only supporting the control-flow oriented process-intelligence mining techniques, and so it is unable to properly support the relation-oriented process-intelligence mining techniques. Therefore, this paper tries to extend the BPAF1.0 so as to reasonably support the relation-oriented process-intelligence mining techniques, and the extended BPAF is termed BPAF2.0. Particularly, we have a plan to standardize the extended BPAF2.0 as not only the national standard specifications through the e-Business project group of TTA, but also the international standard specifications of WfMC.

The Effects of Institutional Block Ownership on Market Liquidity (기관투자자의 대량주식보유가 시장유동성에 미치는 영향)

  • Cho, Kyung-Shick;Jung, Heon-Yong
    • Management & Information Systems Review
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    • v.33 no.1
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    • pp.83-97
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    • 2014
  • This study examined the effects institutional block ownership on the stock market liquidity in Korean Stock Market. The two measures of institutional block ownership are used. They are the percentage of a stock owned by institutional blockholder and the number of institutional blockholder that own the stock. This study used the Amihud(2002) illiquidity measure to measure stock market liquidity. The results are as fellows. First, this study showed that the number of institutional blockholder is significantly negatively correlated with the Amihud(2002) illiquidity measure in the analysis which is used the whole data. But we found no a consistent results between the number of institutional blockholder and the Amihud(2002) illiquidity measure in the grouped institutional blockholder's number analysis. This indicates that the effects institutional blockholder on market liquidity is not simple. Second, this study showed that the percentage of a stock owned by institutional blockholder are negatively related with Amihud(2002) illiquidity measure, especially revealed statistically significant in the group 3(11.71%~17.38%) and group 4(7.45%~11.65%). This results suggest that the institutional blockholder have positive effect on the market liquidity in the group 3 and 4. Third, the significance of the percentage of institutional block ownership and the number of institutional block ownership in explaining illiquidity are more showed in the term of the global financial crisis(2008) than the before and the after of the global financial crisis.

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A Study on factors affecting the viewer rating of"My Little Television": Focusing on SNS Big Data (마이리틀 텔레비전 시청률에 영향을 미치는 요인에 관한 연구 : SNS 빅데이터 중심으로)

  • Kim, Sang-Cheol;Kim, Kwang-Ho
    • Journal of Digital Contents Society
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    • v.17 no.1
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    • pp.1-10
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    • 2016
  • < My Little Television > with the new format which extends one person media broadcasting to terrestrial broadcasting is creating a huge Topic Index. It started the first broadcast on April 2015 and has continued the number one in viewer rating in the same time. While viewers directly participate in the program through the Daum TV Pod and a host communicates with viewers in a real time, various opinions are being reflected on the program. While a lot of information about the program has spread through SNS, it has led to raising the viewer rating of program. Recently, the Topic Index on the program has been published through the big data analysis rather than the program evaluation only by the viewer rating. The research on the correlation between the program viewer rating and amount of buzz has increased. In this study, it has analyzed how the Topic Index which is an extended concept of the amount of buzz affects the viewer rating. Study results show that the Topic Index is analyzed to positively influence the viewer rating. It will give a lot of help in studying big data of SNS on the program.