This study was to optimize the medium components for astaxanthin production in Paracoccus sp. through surface response methodology. A screening test was first conducted on 5 medium components using a Plackett-Burman design, from which $MgSO_4$ and yeast extract were identified as the significant factors affecting astaxanthin production. These significant factors were optimized by central composite design of experiments and response surface methodology, as 2.83 g/L $MgSO_4$ and 7.02 g/L yeast extract, respectively. The expected astaxanthin concentration with these optimized medium compositions were 0.925 mg/L. In flask culture, the experimentally obtained concentration of astaxantin was 1.021 mg/L, where it had been 0.4 mg/L before optimization.
Kim, Ho-Kyung;Cho, Min-Kook;Cheong, Min-Ho;Shon, Cheol-Soon;Hwang, Sung-Jin;Ko, Jong-Soo;Cho, Hyo-Sung
Journal of Radiation Protection and Research
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v.30
no.2
/
pp.69-75
/
2005
Gas avalanche microdetectors, such as micro-strip gas chamber (MSGC), micro-gap chamber (MGC), micro-dot chamber (MDOT), etc., are operated under high voltage to induce large electron avalanche signal around micro-size anodes. Therefore, the anodes are highly exposed to electrical damage, for example, sparking because of the interaction between high electric field strength and charge multiplication around the anodes. Gas electron multiplier (GEM) is a charge preamplifying device in which charge multiplication can be confined, so that it makes that the charge multiplication region can be separate from the readout micro-anodes in 9as avalanche microdetectors possible. Primary electron collection efficiency is an important measure for the GEM performance. We have defined that the primary electron collection efficiency is the fractional number of electron trajectories reaching to the collection plane from the drift plane through the GEM holes. The electron trajectories were estimated based on 3-dimensional (3D) finite element method (FEM). In this paper, we present the primary electron collection efficiency with respect to various GEM operation parameters. This simulation work will be very useful for the better design of the GEM.
Journal of the Korea Academia-Industrial cooperation Society
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v.21
no.6
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pp.227-237
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2020
This study was designed to examine whether the self-directed learning method could improve self-directed learning readiness and the effects of academic achievement level. Self-directed learning readiness was investigated among 63 first-year Medical Terminology undergraduates in the C area. A repeat measurement variance analysis of the general linear model was conducted to evaluate the effects of improving self-directed learning readiness according to the general characteristics and level of academic achievement, while a regression analysis was performed to identify the factors affecting self-directed learning readiness. Self-directed learning readiness increased from 177.3 to 180.8 for those under 18 years of age, and 192.9 to 196.5 for those over 19 years of age (p<0.05). After the team activity, the overall self-directed learning readiness was improved, and both high- and low-achieving groups showed statistically significant improvements (p<0.05). The environment surrounding learners was confirmed to have a positive effect on improving self-directed learning when given the right degree of self-directed learning and appropriate feedback. The study results are expected to form basic foundation material for professors and class designers who want to draw self-directed learning skills from memorizing subjects.
In this study, for the purpose of water supply planning, we propose a sophisticated multi-period mixed integer programming model that can coordinate the behavior of multi-reservoir operation, minimizing unnecessary spill. It can simulate the system with operating rules which are self- generated by the optimization engine in the algorithm. It is an optimization model in structure, but it indeed simulates the coordinating behavior of multi-reservoir operation. It minimizes the water shortfalls in demand requirements, maintaining flood reserve volume, minimizing unnecessary spill, maximizing hydropower generation release, keeping water storage levels high for efficient hydroelectric turbine operation. This optimization model is a large scale mixed integer programming problem that consists of 3.920 integer variables and 68.658 by 132.384 node-arc incidence matrix for 28 years of data. In order to handle the enormous amount of data generated by a big mathematical model, the utilization of DBMS (data base management system)seems to be inevitable. It has been tested with the Han River multi-reservoir system in Korea, which consists of 2 large multipurpose dams and 3 hydroelectric dams. We demonstrated successfully that there is a good chance of saving substantial amount of water should it be put to use in real time with a good inflow forecasting system.
The objective of this study was to examine whether there is an association of oral health conditions between mothers and their preschool children in Korea. A sample of 823 preschool children and their mothers were selected for this study from the database of the fourth Korean National Health and Nutrition examination Survey. Preschool children were defined as children aged 4, 5, and 6 years old. The subjects were clinically examined for the presence of caries lesions (dft index) and their mother was checked for the presence of dental caries (DMFT index) and periodontal status (CPI). The socio-demographic characteristics and mother's oral health behaviours were considered covariates in this study. Univariate and multivariate analysis was adapted to assess the association of oral health condition between mothers and their preschool children. In univariate analysis, there were significant differences between preschool children's dft index and their mother's age (p=0.005), dental treatment demand for the past one year (p=0.034), and DMFT index (p=0.016). In multivariate analysis, only mother's DMFT index was significantly associated with their children's dft index after adjusting for covariates. In conclusion, the mother's oral health was partly associated with their preschool children's oral health in Korea.
Journal of the Computational Structural Engineering Institute of Korea
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v.30
no.5
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pp.405-413
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2017
In this paper, we study the biaxial buckling analysis of nonlocal MEE(magneto-electro-elastic) nano plates based on the first-order shear deformation theory. The in-plane electric and magnetic fields can be ignored for MEE(magneto-electro-elastic) nano plates. According to magneto-electric boundary condition and Maxwell equation, the variation of magnetic and electric potentials along the thickness direction of the MME plate is determined. In order to reformulate the elastic theory of MEE(magneto-electro-elastic) nano-plate, the nonlocal differential constitutive relations of Eringen is used. Using the variational principle, the governing equations of the nonlocal theory are discussed. The relations between nonlocal and local theories are investigated by computational results. Also, the effects of nonlocal parameters, in-plane load directions, and aspect ratio on structural responses are studied. Computational results show the effects of the electric and magnetic potentials. These computational results can be useful in the design and analysis of advanced structures constructed from MEE(magneto-electro-elastic) materials and may be the benchmark test for the future study.
The purpose of this study was to evaluate the applicability of hybrid ventilation system in apartment housings and present a design method to improve the performance of hybrid ventilation system using the CFD simulation. As the object of CFD simulation, a small apartment houses with area of $51m^2$ and $81m^2$ were selected and evaluated. The test hybrid ventilation system are window frame natural air supply & duct exhaust hybrid system(Hybrid 1) and window frame natural air supply & bathroom and livingroom exhaust hybrid ventilation system(Hybrid 2). To evaluate the ventilation efficiency, we used the locations of diffuser installed for each system as the variables through the CFD simulation. In the case of Hybrid 1, the ventilation efficiency of the exhaust duct diffuser located on the inside room was higher rather than the exhaust duct diffuser located on the entrance. In the case of Hybrid 2, the most efficient system was the system that the diffuser connecting the bathroom static pressure fan is installed on the center of the living room. The ventilation efficiency of the Hybrid 2 in the case of $51m^2$ type was more than 20% of the Hybrid 1. But, The ventilation efficiency of the Hybrid 2 in the case of $84m^2$ type was more than 14% of the Hybrid 1. Therefore, to apply the Hybrid ventilation, a study that considers various variable should be conducted.
The research which it sees is the simulation research for "The Ecological Diversion of Forest Land-Use System". It accomplished the simulation which applies a permission standard, it developed escape it did a model and the basic draft. From the research which it sees in order to investigate the application characteristic of natural intimate mountain district application standard the mountain district whole aspect instance middle actual object a time mountain district use standard about under selecting which it will yell it applied. "Natural intimate mountain district development standard triangular position plan research" from compatibility of the mode of life mountain district whole aspect permission standard which is proposed about under investigating it presented the improvement program and a institutional improvement direction of corresponding standard. About under preserving plan it applies the yearly environment the mountain district to sleep it prepares the foundation for it accomplished the transcendental research for. With the achievement resources which the mountain district has resultantly must preserve a value, limit of the development size it will be able to minimize the effect which it follows in development, the arrangement method back could be proposed, also the case which will use the mountain district where it is damaged induces the development which cabinets to the concept of demobilization, the case which will apply the existing forest resources takes a triangular position with the act it will be able to increase the circulating value of the resources and will do.
Magazine of the Korean Society of Agricultural Engineers
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v.37
no.3_4
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pp.34-47
/
1995
It is experienced fact as a regular annual event that the structure to he designed on unreasonable flood for the agricultural structures including reservoirs have been brought not only loss of lives, but also enormous property damage. For the solution of this problem at issue, this study was conducted to develop an optimal runoff hydrograph model by comparison of the peak flows and time to peak between observed and simulated flows derived by linear time-invariant and linear time-variant models under the condition of having a short duration of heavy rainfall with uniform rainfall intensity at nine small watersheds which are within the range of 55.9 to 140.7 square kilometers in area in Han, Geum, Nagdong and Yeongsan Rivers. The results obtained through this study can be summarized as follows. 1. Storage constants and Gamma function arguments were calculated within the range of 1.2 to 6.42 and of 1.28 to 8.05 respectively by the moment method as the parameters for the analysis of runoff hydrograph based on linear time-invariant model. 2. Parameters for both linear time-invariant and linear time-variant models were calibrated with nine gaged watershed data, using a trial and error method. The resulting parameters including Gamma function argument, N and storage constant, K for linear time-invariant model were related statistically to watershed characteristic variables such as area, slope, length of main stream and the centroid length of the basin. 3. Average relative errors of the simulated peak discharge of calibrated runoff hydrographs by using linear time-variant and linear time-invariant models were shown to be 0.75 and 5.42 percent respectively to the peak of observed runoff hydrographs. Correlation coefficients for the statistical analysis in the same condition were shown to be 0.999 and 0.978 with a high significance respectively. Therefore, it can be concluded that the accuracy of a linear time-variant model is approaching more closely to the observed runoff hydrograph than that of a linear time-invariant model in the applied watersheds. 4. Average relative errors of the time to peak of calibrated runoff hydrographs by using linear time-variant and linear time-invariant models were shown to be 16.44 and 19.89 percent respectively to the time to peak of observed runoff hydrographs. Correlation coefficients in the same condition were also shown to be 0.999 and 0.886 with a high significance respectively. 5. It can be seen that the shape of simulated hydrograph based on a linear time- variant model is getting closer to the observed runoff hydrograph than that of a linear time-invariant model in the applied watersheds. 6. Two different models were verified with different rainfall-runoff events from data for the calibration by relative error and correlation analysis. Consequently, it can be generally concluded that verification results for the peak discharge and time to peak of simulated runoff hydrographs were in good agreement with those of calibrated runoff hydrographs.
The Journal of the Convergence on Culture Technology
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v.6
no.2
/
pp.271-280
/
2020
Purpose : The purpose of this study examines the mediating effect of women leader's characteristics in the relationship between clan culture and market culture of global companies. In addition, this study attempts to analysis the mediating effect of women leader's position and carrier in the relationship among facilitator, mentor, producer, and director leadership using partial mediation and completed mediation model. Research design, data, methodology : Conceptual research model is designed with three constructs such as clan culture, woemn leader's characteristics, and market culture. Based on five hundred cases with leadership styles and organizational culture of global companies, this study examine the mediating effect of women leader's characteristics in the relationship between clan culture and market culture using structured equation modeling. Results : Facilitator leadership have a significantly positive influence on women leader's position and carrier. Mentor leadership have a significantly positive influence on women leader's carrier while they are not correlated with mentor leadership and women leader's position. Women leader's position and carrier have a significantly positive influence on director leadership while women leader's position and carrier not have a positive influence on procucer leadership. Also facilitator and mentor leadership have a significantly positive on producer and director leadership. Conclusions : By controlling for the mediating effect of women leader's characteristics, this study have improved the academic contributions as well as policy and practical implications through empirical study of clan culture that affect market culture in the filds of leadership style and organizational. In addition, this study means that the mediating effects on the variables of women leader's position and carrier were examined.
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