• Title/Summary/Keyword: 생존요인

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Long-Term Survival Benefit of the Bronchial Arterial Embolization for Patients Presenting with Non-Traumatic Hemoptysis in a District Emergency Center (권역 응급의료센터에 내원한 비외상성 객혈 환자에서 기관지 동맥 색전술의 장기 생존 효과)

  • Chon, Song Bin;Jung, Sung Koo;Kwak, Young Ho;Suh, Gil Joon;You, Eun Young;Shin, Sang Do
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.2
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    • pp.148-159
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    • 2004
  • Background : This study was conducted to evaluate the survival benefit of the bronchial arterial embolization (BAE) for patients presenting with non-traumatic hemoptysis. Methods : The clinical data were retrospectively collected from the medical records and the Order Communicating Systems (OCS). The information dealing with death was collected from national death certificates. After enrolled patients were divided with two group such as BAE group (patients who were managed with BAE) and non-BAE group (patients who were managed with conservative modality), the survival benefit of BAE was estimated during the observational period of 24 months through using the Kaplan-Meier survival graph and the Cox-proportional hazard regression analysis. Results : The number of total cases was 272. Of these, BAE group involved 63 and non-BAE group involved 209. 69 cases had the malignant pulmonary lesions, 149 cases had non-malignant chronic lung lesion such as the mycobacteria infection, fungus ball, or bronchiectasis (BE), and 54 cases had the other pathologic conditions. For each sub-groups such as 'malignant lung lesion' group, 'non-malignant chronic lung lesion' group as well as about all cases, the adjusted hazard ratios (HRs) of BAE for death was not significantly different compared to the conservative management. But the adjusted HRs as to underlying causes such as 'malignant lung lesion' group and 'the other conditions' group increased significantly compared to 'non-malignant chronic lung lesion' group. Conclusion : There was no significant survival benefit by BAE procedure on survival in patients presenting with non-traumatic hemoptysis.

The Effect of Equity Crowdfunding on Job Creation (주식형 크라우드 펀딩이 고용창출에 미치는 효과)

  • Chun, Hesuk
    • The Journal of the Korea Contents Association
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    • v.15 no.12
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    • pp.541-549
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    • 2015
  • Research about U.S. and European countries demonstrated that startups and young firms account for nearly all net job creation. If we want to bring down unemployment and to increase economic growth rate, we need to create new companies and to make them to grow. Credit availability is one of the most important factors for entrepreneurs as they attempt to start or expand a business. For young firms, access to credit for business growth can mean the difference between survival and failure. Equity crowdfunding is an innovative means of raising capital for businesses. Crowdfunding campaigns can give new business access to a large pool of investors. This brings huge benefits for marketing and increase provability of success of business and ROI, so it leads follow-on investment from Venture Capital and Angel investors. In Korea, the survival rate of startups and average growth rate of survivors is far lower than those of the U.S or other countries due to lack of funds for startup or early business growth. Equity crowdfunding can be a new funding source for venture or startups. It can increase startup and survival rate, in addition to the growth rate of survivors, resulting in decreased unemployment rate. In Korea, Equity crowdfunding will be available from 2016. Further study is needed to determine whether the impact of crowdfunding in Korea on job creation will be similar to its impact in the U.S.

The Prediction of Survival of Breast Cancer Patients Based on Machine Learning Using Health Insurance Claim Data (건강보험 청구 데이터를 활용한 머신러닝 기반유방암 환자의 생존 여부 예측)

  • Doeggyu Lee;Kyungkeun Byun;Hyungdong Lee;Sunhee Shin
    • Journal of Korea Society of Industrial Information Systems
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    • v.28 no.2
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    • pp.1-9
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    • 2023
  • Research using AI and big data is also being actively conducted in the health and medical fields such as disease diagnosis and treatment. Most of the existing research data used cohort data from research institutes or some patient data. In this paper, the difference in the prediction rate of survival and the factors affecting survival between breast cancer patients in their 40~50s and other age groups was revealed using health insurance review claim data held by the HIRA. As a result, the accuracy of predicting patients' survival was 0.93 on average in their 40~50s, higher than 0.86 in their 60~80s. In terms of that factor, the number of treatments was high for those in their 40~50s, and age was high for those in their 60~80s. Performance comparison with previous studies, the average precision was 0.90, which was higher than 0.81 of the existing paper. As a result of performance comparison by applied algorithm, the overall average precision of Decision Tree, Random Forest, and Gradient Boosting was 0.90, and the recall was 1.0, and the precision of multi-layer perceptrons was 0.89, and the recall was 1.0. I hope that more research will be conducted using machine learning automation(Auto ML) tools for non-professionals to enhance the use of the value for health insurance review claim data held by the HIRA.

Discrete-Time Survival Analysis of the Determinants of the Onset of Adolescents' Status Delinquency (비연속시간 생존분석을 활용한 청소년의 최초 지위비행에 대한 영향요인 분석)

  • Yun, Hongju
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.459-467
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    • 2021
  • This study examined the onset of adolescent delinquency through discrete-time survival analysis. Our analysis used data obtained from the Korean Children & Youth Panel Survey, and included 2,277 middle school students. The main analysis results are as follows. First, the hazard probability for the occurrence of delinquency was the highest at 16.6% in the second year of middle school, slightly decreased in the third year of middle school, but continued to increase as the overall grade increased. Second, adolescent psychological and emotional factors have significantly affected the onset of delinquency. Third, negative parenting methods had a significant impact on delinquency, but neglect was not significant. Fourth, having delinquent friends was an important factor affecting the status of delinquency. Fifth, among the school factors, adjustment of learning activities, adjustment of school rules, and adjustment of friendship relations influenced the status of delinquency, while the adjustment of teacher relations was not significant. As early intervention is important to prevent juvenile delinquency, education and support for establishing healthy relationships are needed.

Isolation, Culture and Electroporation of Rice Protoplasts (벼 원형질체의 분리, 배양 및 Electroporation에 관한 연구)

  • 황성진
    • Journal of Plant Biology
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    • v.34 no.1
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    • pp.19-23
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    • 1991
  • Culture of embryogenic callus and suspension were induced from rice seeds in MS2.5 medium. In hormone free N6 medium, whole plantlets were regenerated from embryogenic callus. We observed cell division and reformation of embryogenic callus on culture of protoplast isolated from embryogenic cell suspensions. In addition, we studied the influencing factors on viability of protoplast treated with electroporation. Viability was decreased according to the increase of voltage and capacitance during electroporation. An optimal level of viability was obtained after treatment with $200-300\;V/1180\;\mu\textrm{F}$ in HEM buffer at $4^{\circ}C$..

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Cd 및 Cu의 노출에 따른 넙치, Paralichthys olivaceus의 생존 및 성장

  • Jin, Pyung;Shin, Yoon-Kyung;Ji, Jung-Hoon;Lee, Jung-A;Lee, Jung-Sik;Kang, Ju-Chan
    • Proceedings of the Korean Society of Fisheries Technology Conference
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    • 2001.10a
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    • pp.329-330
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    • 2001
  • 연안의 오염으로 인한 수생생물의 피해를 파악하기 위하여 여러방면으로 연구가 진행되고 있다. 특히 여러 오염원에 대한 수생생물의 생존과 성장은 중요한 평가요인이 될 수 있다(Marr et al., 1996). 이들 중금속에 대한 여러 연구들이 현재 진행 되 고 있으며 (Gagne' et al.,1990; Castano et al.,1998), 현재 우리나라 연안에 분포하는 중금속에 대한 수생생물의 영향분석의 일환으로 구리 및 카드륨이 넙치의 생존, 성장 및 사료효율에 미치는 만성적 영향을 파악하는 것을 본 연구의 목적으로 한다. (중략)

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A Study of Survivability Improvement Method for Naval Ships′Design I - Design Method Considering Box Girder - (함정 설계의 생존성 향상 방안에 관한 연구 I - Box Girder를 고려한 설계 방법 -)

  • Kim, Jae-Hyun;Park, Myeong-Gyu
    • Journal of Navigation and Port Research
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    • v.27 no.2
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    • pp.199-207
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    • 2003
  • In the combat environments at the sea, the naval ships should have enough structural integrity to perform the task under the enemy's attack and possible damages. Although the naval ships can be damaged from the enemy's attack, those damages should be minimized and the naval ships must maintain their combat capabilities continuously after recoveries from the damages. Therefore, it is ve교 important for modem naval ships, especially combat naval ships, to ensure the survivability. This paper reviewed the developing procedure for the technique of the naval ships structures and described method, especially box girder system considering survivability. The efficiency of box girder is examined by numerical simulation, and it is found that the establishment of box girder is a good design method to improve the survivability.

Effects of Environmental Factors and Live Food on Growth and Survival Rate of Zoea and Mysis Larvae of Fleshy Shrimp, Penaeus chinensis (대하 (Penaeus chinensis)의 Zoea와 Mysis기 유생의 성장과 생존율에 미치는 환경요인 및 먹이생물의 영향)

  • KIM Hyun Jun;HUR Sung Bum
    • Journal of Aquaculture
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    • v.6 no.3
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    • pp.159-171
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    • 1993
  • The effects of environmental factors (density, light, temperature) and live food on growth and survival rate of zoea and mysis of fleshy shrimp, Penaeus chinensis, were examined. The percent survival rates at the culture densities of 200 and 300 larvae per liter were significantly higher than that of 500 larvae per liter (p< 0.05). The percent survival rates at the culture densities of 100, 200, 300 and 500 larvae per liter were $90.3^{ab},\;95.2^a,\;94.3^a\;and\;86.7^b\%$ (p< 0.05). The effects of light conditions with diatom premix diet showed that continuous light was the best for the survival rate, $96.5\%$. Natural light and continuous darkness showed the survival rates $79.0\%\;and\;4.3\%$, respectively. On the rearing temperature, the survival rates were $97.3\%\;at\;19^{\circ}C\;and\;96.7\%\;at\;22^{\circ}C$ with little difference but the higher temperature resulted in faster growth. The survival rate was $51.6\%;at\;25^{\circ}C$ thus showing significant decrease compared to $19^{\circ}C\;and\;22^{\circ}C$. At this temperature the growth was also suffered. With regard to dietary value of live food, both the best survival rate and the fastest growth were obtained when 6 mixed species of diatom (A. normaii, C. simplex, N closterium, P. tricornutum, S. costatum and T. weissflogii) were provided. When single species was supplied the best survival rate $(82.1\%)$ was obtained with S. costatum, but the other species resulted in much inferior survival rates $(below\;80.0\%)$ and poor growth.

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A Study on the Survival Probability and Survival Factors of Small and Medium-sized Enterprises Using Technology Rating Data (기술평가 자료를 이용한 중소기업의 생존율 추정 및 생존요인 분석)

  • Lee, Young-Chan
    • Knowledge Management Research
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    • v.11 no.2
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    • pp.95-109
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    • 2010
  • The objectives of this study are to identify the survival function (hazard function) of small and medium enterprises by using technology rating data for the companies guaranteed by Korea Technology Finance Corporation (KOTEC), and to figure out the factors that affects their survival. To serve the purposes, this study uses Kaplan-Meier Analysis as a non-parametric method and Cox proportional hazards model as a semi-parametric one. The 17,396 guaranteed companies that assessed from July 1st in 2005 to December 31st in 2009 are selected as samples (16,504 censored data and 829 accident data). The survival time is computed with random censoring (Type III) from July in 2005 as a starting point. The results of the analysis show that Kaplan-Meier Analysis and Cox proportional hazards model are able to readily estimate survival and hazard function and to perform comparative study among group variables such as industry and technology rating level. In particular, Cox proportional hazards model is recognized that it is useful to understand which technology rating items are meaningful to company's survival and how much they affect it. It is considered that these results will provide valuable knowledge for practitioners to find and manage the significant items for survival of the guaranteed companies through future technology rating.

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Radiotherapy in Medically Inoperable Early Stage Non-small Cell Lung Cancer (내과적 문제로 수술이 불가능한 조기 비소세포성 폐암에서의 방사선치료)

  • Kim, Bo-Kyoung;Park, Charn-Il
    • Radiation Oncology Journal
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    • v.18 no.4
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    • pp.257-264
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    • 2000
  • Purpose: For early stage non-small-cell lung cancer, surgical resection is the treatment of choice. But when the patients are not able to tolerate it because of medical problem and when refuse surgery, radiation therapy is considered an acceptable alternative. We report on the treatment results and the effect of achieving local control of primary tumors on survival end points, and analyze factors that may influence survival and local control. Materials and Method : We reviewed the medical records of 32 patients with medically inoperable non-small cell lung cancer treated at our institution from June, 1987 through June, 1997. All patients had a pathologic diagnosis of non-small cell lung cancer and were not candidate for surgical resection because of either patients refusal (4), old age (2), lung problem (21), chest wail invasion (3) and heart problems (3). In 8 patients, there were more than 2 problems. The median age of the patients was 68 years (ranging from 60 to 86 years). Histologic cell type included souamous (24), adenocarcinoma (6) and unclassiried squamous cell (2). The clinical stages of the patients were 71 in 5, 72 in 25, 73 in 2 patients. Initial tumor size was 3.0 cm in 11, between 3.0 cm and 5.0 cm in 13 and more than 5.0 cm in 8 patients. Ail patients had taken chest x-rays, chest CT, abdomen USG and bone scan. Radiotherapy was delivered using 6 MV or 10 MV linear accelerators. The doses of primary tumor were the ranging from 54.0 Gy to 68.8 Gy (median; 61.2 Gy). The duration of treatment was from 37 days through 64 days (median; 0.5 days) and there was no treatment interruption except 1 patient due to poor general status. In 12 patients, concomitant boost technique was used. There were no neoadjuvant or adjuvant treatments such as surgery or chemotherapy. The period of follow-up was ranging from 2 months through 93 months (median; 23 months). Survival was measured from the date radiation therapy was initiated. Results : The overall survival rate was 44.6$\%$ at 2 years and 24.5$\%$ at 5 years, with the median survival time of 23 months. of the 25 deaths, 7 patients died of intercurrent illness, and cause-specific survival rate was 61.0$\%$ at 2 years and 33.5$\%$ at 5 years. The disease-free survival rate was 38.9$\%$ at 2 years and 28.3$\%$ at 5 years. The local-relapse-free survival rate was 35.1$\%$, 28.1$\%$, respectively. On univariate analysis, tumor size was significant variable of overall survival (p=0.0015, 95$\%$ C.1.; 1.4814-5.2815), disease-free survival (P=0.0022, 95$\%$ C.1., 1.4707-5.7780) and local-relapse-free survival (p=0.0015, 95$\%$ C.1., 1.2910- 4.1197). 7 stage was significant variable of overall survival (p=0.0395, 95$\%$ C.1.; 1.1084-55.9112) and had borderline significance on disease-free survival (p=0.0649, 95$\%$ C.1.; 0.8888-50.7123) and local-relapse-free survival (p=0.0582, 95$\%$ C,1.; 0.9342-52.7755). On multivariate analysis, tumor size had borderline significance on overall survival (p=0.6919, 955 C.1., 0.9610-5.1277) and local-relapse-free survival ( p=0.0585, 95$\%$ C.1.; 0.9720-4.9657). Tumor size was also significant variable of disease-free survival (p=0.0317, 95% C.1.; 1.1028-8.4968). Conclusion : Radical radiotherapy is an effective treatment for small (71 or f3 cm) tumors and can be offered as alternative to surgery in elderly or infirmed patients. But when the size of tumor is larger than 5 cm, there were few long-term survivors treated with radiotherapy alone. The use of hypefractionated radiotherapy, endobronchial boost, radisensitizer and conformal or IMRT should be consider to improve the local control rate and disease-specific survival rate.

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