• 가정의 벗
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• 제34권12호통권400호
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• pp.7-7
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• 2001

• 대한한의학회지
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• 제25권2호
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• pp.22-32
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• 2004

Objectives: In order to determine the effect of CPs, experimental studies were performed in hyperlipidemia humans. The contents of serum total cholesterol, TG (triglyceride), LDL cholesterol, HDL cholesterol, AST/ALT and BUN/creatinine were measured. Methods: We made a comparative study of total cholesterol, TG (triglyceride), LDL cholesterol, HDL cholesterol, AST/ALT and BUN/creatinine during one month off and on for twenty patients with hyperlipidemia who visited Gunpo Oriental Medical Center of Wonkwang University from December 2002 to July 2003. Results: The following result were obtained: 1. The serum TG and total cholesterol of patients who took CPs for one month showed significant (p<0.01) decrease. 2. The serum HDL-cholesterol and LDL-cholesterol of patients who took CPs for one month showed significantly increase in HDL, and decrease in LDL (p<0.05). 3. The serum AST/ALT and BUN/creatinine of patients who took CPs for one month showed no significant effects. Conclusions: According to the results mentioned above, the effects of CPs on serum triglyceride and total cholesterol of hyperlipidemia patients were significantly confirmed for decreasing effects.

• 동아시아식생활학회지
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• 제18권4호
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• pp.455-465
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• 2008

강화 지역의 전통음식, 시절식과 12달 동안의 절기식 및 출산시, 삼칠일, 백일, 돌, 화갑, 혼례 등의 통과 의례 음식에 대한 조사를 실시하여 전통문화의 계승 발전에 필요한 기초자료를 제시하고자 강화에서 20대 전후부터 거주하여 30년 이상 계속 거주한 50대를 대상으로 설문 조사하였다. 그 결과, 절기식은 정월대보름(87.5%), 추석(84.4%), 정월초하루 설날(79.8%), 동지(77.4%)로 주로 농사와 관련된 명절이 우세한 것으로 보였다. 통과 의례 음식 중 돌상은 86.4%가 차렸으며, 백설기, 수수팥떡, 송편, 인절미, 과일, 잡채 등의 음식이 전통적으로 사용되었다. 또한, 아이 낳은 산모에게 쌀밥과 미역국을 대접하는 경우가 367명(96.1%)이었다. 생일상을 집에서 차리는 경우는 256명(67.0%), 차리지 않는 경우는 126명(33.0%)이었다. 차리지 않는 이유는 '시간이 없어서'는 38.2%, '귀찮아서'는 19.4%로 57.6%를 차지하였다. 폐백상차림은 육포(닭), 대추, 밤이 기본적인 음식이었으며, 회갑상을 차리는 경우는 120명(31.4%)이었다. 제사를 장남집에서 모신다고 한 경우는 53.4%이었으며, 제사가 필요한 이유는 관습대로 지키는 것보다 조상에게 감사하는 마음이 더 많았다(p<0.05). 제사 음식은 주로 천주교는 친정어머니(66.7%)에게서 배우고, 불교는 37.9%, 유교는 54.5%가 시어머니에게서 배워 종교간에 유의적인 차이를 보였다(p<0.05). 임신 중 금기 식품은 개고기, 게장, 꽃게, 닭고기, 오리고기, 토끼고기, 팥죽, 팥밥, 커피, 모난 것, 물렁뼈가 있는 것, 불결한 모양, 비늘 없는 생선이라고 하였다. 이와 같이 시대가 지남에 따라 전통적인 의례 행사가 많이 변형되고 쇠퇴하는 것을 볼 수 있는데, 앞으로 지역의 축제나 전시회, 품평회, 대중매체를 통해 꾸준한 홍보 활동 등으로 전통의 맥을 이어야 하겠다.

• 대한가정학회지
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• 제45권1호
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• pp.63-73
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• 2007

Korean children's clothes have unique aesthetic characteristics distinguished from other countries'. Our folk beliefs handed down from ancient times always contained fortune - seeking thoughts and particularly mothers' earnest wishes for the happiness of their children were sublimated into the symbolic beauty of their children's clothes. The present study examined children's clothes in the royal family and among the people for 50 years of the transitional period from the late Joseon Dynasty to modern times, by classifying them into ritual dress for new-born babies, festival dress and everyday dress. Male children's clothes included caps such as Bokgeon(복건), Hogeon(호건) and Gulle(굴레) topcoats such as Durumagi(두루마기), Sagyusam(사규삼) Koija(쾌자) and Jeonbok(전복) and others such as Magoja(마고자), Baeja(배자), Joggi(조끼) and Bajijeogori(바지저고리), Female children's clothes included caps and head ornaments such as Gulle, Jobawi(조바위) and Daenggi(댕기) and others such as Durumagi, Jegori and Chima(치마). What is interesting is that old clothes handed down to the present are mostly boys' and few of them are girls'. This is probably because of the strong preference for boys rather than girls that continued until the end of the 20th century. Ordinary people dressed their new - born babies with simple white clothes until Samchilil (the 21st day) or Baekil (the 100thday) but, for these occasions, the royal family prepared clothes as formal as those for the $1^{st}$ birthday among the public. Rainbow-striped garments were more popular among the public than in the royal family. As rainbow colors were known to Korean people to dispel evil power and bring in fortunes, rainbow - striped garments were essential for the $1^{st}$ birthday and festive days. However, they were seldom used in ordinarytimes, and most boys and girls wore plain jackets and plain topcoats. When children's clothes in noble families were compared with royal family's ones, either handed down to the present or found in old literature, no significant difference was observed in the basic composition of everyday dress. In particular, it was found that Andong Kim's family had dressed their children with very formal dress such as Dopo and Sagyusam. Among children's clothes, the most gorgeous one was that worn on the $1^{st}$ birthday, and those for other occasions or festive days were similar or simpler. Colors, patterns and designs used in decorating children's clothes mostly had the meanings of seeking fortunes for children such as long life, wealth and prosperity.

• 여성건강간호학회지
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• 제13권4호
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• pp.299-309
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• 2007

Purpose: The purpose of this study was to compare the predictors between the early and late postpartum period in parturient women. Methods: The Subjects were 399 healthy postpartum women who visited the obstetric clinic at 5 hospitals for a routine check up after childbirth. They were divided into two groups: one was in the early postpartum period, the first three weeks after childbirth (n=107), the other was in the late postpartum period, four to six weeks after childbirth (n=292). The data were collected by using a self-report questionnaire from July to September, 2006. The data were analyzed with the SPSS 12.0 Win program. Results: There were significant statistical differences in age and parity between the two groups. Postpartum fatigue was significantly predicted by postpartum depression and age in the early period, and postpartum depression, sleep satisfaction, and childcare stress in the late period. The mean scores of childcare stress and perceived infant difficulty in the late period were significantly higher than those of the early postpartum period. Conclusion: Postpartum depression was the most important predictor of postpartum fatigue regardless of the postpartum period. In addition, especially in the late period, sleep satisfaction and childcare stress were significant predictors of postpartum fatigue. Based on these results, primary nursing interventions for reducing postpartum fatigue should focus on postpartum depression management, and nursing interventions for increasing sleep satisfaction and decreasing childcare stress would be helpful for management of postpartum fatigue in parturient women in the late period.

• 동의생리병리학회지
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• 제22권4호
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• pp.863-870
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• 2008

The aim of this study was to investigate that Injinoryung-san-Ga-Samchilgun(IJORS) has an inhibitory effect on the development of liver fibrosis in rats. The influence of IJORS on liver stellate cell viability in rat was measured by the MTT assay, and proliferation was measured by the BrdU assay. The mRNA expression of procollagen type $1{\alpha}2$, ${\alpha}-SMA$, TIMP1, and TIMP2 all of which are associated with liver fibrosis, were analyzed by RT-PCR. The inhibitory effect of IJORS on procollagen production in hepatic stellate cell was examined using by enzyme immuno assay(procollagen Type 1 C-Peptide EIA). And after IJORS was orally administered to experimental rats with thioacetamide(TAA)-induced liver fibrosis for 4 weeks, the body weight, liver function test, complete blood and the change of portal pressure were measured. IJORS prevented hepatic stellate cell viability and proliferation in a dose-dependent manner. IJORS reduced the mRNA expression of procollagen type $1{\alpha}2$, ${\alpha}-SMA$ and TIMP1 and the production of procollagen protein. IJORS inhibited the increase of AST, ALT, WBC and portal pressure in rats administered by TAA. IJORS is considered to prevent liver fibrosis by inhibiting the activation of stellate cell and production of procollagen and prevent the progress of liver fibrosis by inhibiting the inflammation of liver tissue complicated in many liver disease.

• 동의생리병리학회지
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• 제20권5호
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• pp.1187-1195
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• 2006

Panax notoginseng exhibit several beneficial effects including anti-oxidant effects. P. notoginseng is used as a therapeutic agent to stop haemorrhages and a tonic to promoted health in Korean and Chinese medicine. The pharmacokinetic profiles of the main P. notoginseng are still not accurately investigated. The exact mechanism of the anti-oxidant activitys of water extracts of P. notoginseng, however, has not been determined. in present study, I examined the effects of water extracts of P. notoginseng on high cholesterol diet atherosclerosis-induced rats in serum and abdominal aorta. A total of 3-week old 9 male rats of Sprague-Dawley were divided into 3 groups and fed with the basal diet (normal group), high cholesterol diet (atherosclerosis induced group) for 8 weeks, high cholesterol diet supplemented with water extracts of P. notoginseng (P. notoginseng group) for 4 weeks. And rats were sacrificed, serum lipid level, abodominal aortic anti-oxidant activities and lipid peroxide were measured. These results indicated that serum total cholesterl, LDL-cholesterol, triglycerides concentration significently lowered in P. notoginseng group than high cholesterol diet group. But HDL-cholesterol concentraion significently higher in P. notoginseng group than high cholesterol feed group. And abdominal aortic xanthine oxidase activity was significantly reduced by dietary water extracts of P. notoginseng supplementation (p<0.05) Also abdominal aortic superoxide dismutase, catalase, glutathione peroxidase activities were significantly increased by dietary water extracts of P. notoginseng supplementation (p<0.05) Especially, abdominal aortic level of lipid peroxide tended to increase in high cholesterol feed group, but water extract of P. notoginseng intake reduced the value (p<0.05).

• 한국응용과학기술학회지
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• 제35권1호
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• pp.43-54
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• 2018

본 연구에서는 삼칠화 에탄올 추출물의 항산화 및 피부 세포 독성, 항염증을 확인하고, 삼칠화 함유 화장품을 여드름 피부에 적용하여 수분, 홍반, 모공, 블랙헤드에 미치는 영향을 분석하여 화장품 소재로서의 가능성을 규명하고자 하였다. 연구 결과, 삼칠화 에탄올 추출물의 DPPH radicial 소거능을 확인하였고, 높은 폴리페놀 함량과 플라보노이드 함량을 나타내었다. 삼칠화 에탄올 추출물은 RAW 264.7 세포에 대한 독성이 적었고, LPS에 의해 유도된 NO 생성을 유의하게 억제하는 것을 확인하였다. 4주간 삼칠화 에탄올 추출물이 3% 함유된 스킨 토너와 스팟 솔루션을 여드름 피부에 적용한 결과, 수분 증가와 홍반지수, 눈에 띄는 모공수, 블랙헤드 감소가 유의하게 나타났고, 사용 후 만족도 조사에서 피지량 감소, 붉음증 완화에 대한 만족도가 높은 것을 확인하였다. 따라서 삼칠화는 항산화 및 항염증 효과가 있으며, 여드름 관리용 화장품 소재로서 활용 가능할 것으로 사료된다.

• 한국식품저장유통학회지
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• 제18권4호
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• pp.620-625
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• 2011

당뇨병에 효과가 있는 식품소재의 탐색과 그 소재를 이용한 기능성 빵제품 개발에 관한 연구의 일환으로 당뇨병에 효과가 있다고 알려진 소장흡수 저해효소인 ${\alpha}$-glucosidase를 target로 시중에 유통되는 다양한 생약재를 대상으로 탐색을 하였다. ${\alpha}$-Glucosidase 저해활성을 조사하고자 생약재 200여종을 대상으로 물층과 메탄올 층으로 구분하여 탐색한 결과 물층에서는 황기(70.9%)가, MeOH층에서는 구인(72.9%)이 70%이상의 강력한 저해효과를 나타났으며 60%이상으로는 물층에서는 육두구(69%), 상백피(66.9%), 오미자(65%), 삼칠(63.9%), 전호(62.9%), 천문동(62.1%), 정공등(60.9%), 호장근(60.7%), 창출(60.2%), 소자(60.2%)등 이었으며, MeOH층으로는 만삼(67.8%), 도인(67.6%), 방기(63.5%), 동규자(61.6%) 순으로 활성효과를 나타내었으며 50%이상의 저해효과를 보인 것으로는 물층에서는 황정(59.8%), 신곡(59.7%), 택사(59.5%), 의인(59.2%), 세신(59.0%), 시호(53.0%)를 포함한 31여종, MeOH층에서는 사군자(58.8%), 구기자(58.3%), 과루인(58.0%), 백자인(55.9%), 백강잠(55.6%), 계내금(55.4%), 독활(55.3%), 구척(52.7%), 대극(52.7%), 백편두(52.5%) 10종이 저해효과를 나타내었다. 따라서 당뇨병 환자의 기능성 소재로 개발하는데 기초 자료가 될 것으로 기대된다.

• 한국식품과학회지
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• 제37권4호
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• pp.549-556
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• 2005

45종 식용 및 약용식물 에탄을 추출물의 에스트로젠 활성 및 항산화활성을 측정하였고 폴리페놀과 플라보노이드 함량을 측정 비교하였다. 재조합 효모법을 이용하여 에스트로젠 활성을 측정한 결과 감초, 강황, 경포부자, 구아바, 느릅(줄기), 도꾸다미, 백화사설초, 대황, 상백피(중국산), 상황버섯, 석류, 복분자(과육, 씨), 원지, 은행, 초두구, 홍화, 황정이 유의적으로 높은 활성을 나타내었다. 특히, 감초와, 대황은 $100{\mu}g/mL$의 농도에서 1mg/mL 보다 더 높은 활성을 나타내었다. DPPH 라디칼 소거능과 TBARS 생성 억제능 두 가지가 모두 우수한 소재는 감초, 구아바, 느릅, 대황, 복분자, 초두구였다. 총 폴리페놀은 초두구가 594.7mg/g catechin eq.으로 가장 높았으며 삼칠근이 8.6mg/g catechin eq.으로 가장 낮았고, 플라보노이드 함량은 강황이 약 394.9mg/g naringin eq.으로 가장 높았고 황정이 1.7mg/g naringin eq.으로 가장 적었다. 폴리페놀의 함량이 높은 식물의 대부분이 플라보노이드의 함량도 많았다. 시료 추출물의 라디칼 소거 활성과 폴리페놀 함량간에 양의 상관관계를 나타내었으나$(r^2=0.61)$, 지질 과산화 억제능 및 에스트로젠 활성과 폴리페놀 함량 간에는 유의적인 상관성이 적었다. 감초, 대황은 에스트로젠 활성이 높으면서 항산화능이 높았다. 이상의 결과는 파이토에스트로젠 활성을 가진 천연 소재를 선정하는데 기초 자료로 활용될 수 있을 것으로 사료된다.