Effects of CPs (Combined Preparations) of Radix Salvia Miltiorrhiza, Radix Notoginseng, and Borneolum on Hyperlipidemia

CPs(단삼, 삼칠, 빙편 복합제)가 고지혈증에 미치는 영향

  • 이건목 (원광대학교 한의학전문대학원 제3의학과 동서협진한의학) ;
  • 이길숭 (원광대학교 한의학전문대학원 제3의학과 동서협진한의학)
  • Published : 2004.06.01

Abstract

Objectives: In order to determine the effect of CPs, experimental studies were performed in hyperlipidemia humans. The contents of serum total cholesterol, TG (triglyceride), LDL cholesterol, HDL cholesterol, AST/ALT and BUN/creatinine were measured. Methods: We made a comparative study of total cholesterol, TG (triglyceride), LDL cholesterol, HDL cholesterol, AST/ALT and BUN/creatinine during one month off and on for twenty patients with hyperlipidemia who visited Gunpo Oriental Medical Center of Wonkwang University from December 2002 to July 2003. Results: The following result were obtained: 1. The serum TG and total cholesterol of patients who took CPs for one month showed significant (p<0.01) decrease. 2. The serum HDL-cholesterol and LDL-cholesterol of patients who took CPs for one month showed significantly increase in HDL, and decrease in LDL (p<0.05). 3. The serum AST/ALT and BUN/creatinine of patients who took CPs for one month showed no significant effects. Conclusions: According to the results mentioned above, the effects of CPs on serum triglyceride and total cholesterol of hyperlipidemia patients were significantly confirmed for decreasing effects.

Keywords

References

  1. 上海中醫雜誌 no.8 治療高脂血症47例臨床觀察 孫培桐(外)
  2. 臨床脂質學 金辰圭
  3. 家庭醫學會誌 v.8 no.7 高脂血症 이혜리
  4. 慶熙大學校 論文集 v.7 淸暈化痰湯이 脂質代謝에 미치는 影響 金辰泰
  5. 家庭醫學會誌 v.13 no.5 健康診斷을 받은 사람들에게서 나타난 高血壓과 高脂血症의 相關性에 관한 硏究 김용철(외)
  6. 대한의학협회지 v.31 지방질 섭취와 리포단백질대사 채범석
  7. Ann Rev Nutr. v.3 Absorption and metabolism of dietary cholesterol Grundy SM;Metzer AL
  8. 대한내분비학회지 v.4 no.2 콜레스테롤의 운반과 대사 채범석
  9. 국민영양조사 보고서 보건사회부
  10. 한국지질학회지 v.4 no.2 고지혈증의 식사요법 조성희;최영선
  11. JAMA v.251 The Lipid Research Clinics Coronary Prevention Trial Results : Ⅱ, The relationship of reduction in incidence of coronary heart disease to cholesterol lowering The Lipid Research Clinics Program
  12. 중약대사전 강소신의학원(편);김창민;신민교;이경순;안덕균(역)
  13. Arch Intem, Med. v.141 Lipoprpteins, cardiovascular disease and death. The Framingham study Gordon T;WB Kanne;WP Castelli;TR Dawber
  14. JAMA v.254 Lowering blood cholesterol to prevent heart disease CONSENSUS CONFERENCE
  15. 제6회 한국지질학회 추계학술대회 고콜레스테롤혈증의 원인과 치료 이광우
  16. N Engl J Med. v.317 Helsinki Heart Study : Primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia Frick MH;Elo O;Haapa K;Heinonen OP;Heinsalmi P;Helo P(et al.)
  17. J. Korean Acad Fam Med. v.19 no.5 高脂血症 신현호
  18. Clin Chem. v.18 Estimation of the concetration of low-density lipoprotein cholesterol in plasma without use of the preperative ultra centrifuge Friedwald WT;Levy RJ;Frederickson DS
  19. N Engl J Med. v.320 Beyond Cholesterol, Modification of Low-Density-Lipoprotein that increase it, Artherogenecity Steinberg D;Parthasarathy S;Carew TE;Khoo JC;Witztum JL
  20. Endocrinology(2nd ed) Disorder of lipoprotein transport Schonfeld G.;DeGroot LJ(eds)
  21. 제9차 한국지질학회 춘계학술대회 고지혈증의 식이요법에 대한 제언 조여원
  22. Am J Hypertens v.7 Established risk factors and coronary artery disease : The Framingham Study Wilson PWF
  23. Am J Epidemiol. v.114 Serum cholesterol and motality in a Japanese-American population : The Honolulu Heart Program Kagan A;McGee DL;Yano K;Rhoads GG;Nomura A
  24. J Chronic Dis. v.27 Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California : Demographic, physical, dietary and biological characteristics Kagan A;Harris BR;Winkelstein W Jr;Johnson KG;Kato H;Syme SL(et al.)
  25. JAMA v.256 Is relationship between serum cholesterol and risk of premature death from coronary heart disease continous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial(MRFIT) Stamler J;Wentworth D;Neaton JD(for the MRFIT Research Group)
  26. JAMA v.251 The Lipid Research Clinics Coronary Primary Trial results : Ⅰ. Reduction in the incidence of coronary heart disease Lipid Research Clinics Program
  27. J. Korean Acad Fam Med. v.19 no.5 高脂血症 신현호
  28. 생화학(개정11판) Peter Karlson
  29. Lancet v.1 Plasma high density lipoprotein concentration and development of ischemic heart disease Miller GJ;NE Miller
  30. Eur J Clin Invest v.7 Alterations of lipid metabolism in healthy volunteers during long-term ethanol intake Belfrage P;Berg I Hagerstand;P Nilsson-Ehle;H Tomquist;T Wibe
  31. Atherosclerosis v.21 Quantitative and qualitative serum lipoprotein analysis. Part Ⅰ. Studies in healthy men and women Carlson LA;M Ericsson
  32. Am J Epidmiol. v.105 Characteristics of smokers, non-smokers and ex-smokers among 10,000 adult males in Israel. Ⅱ. Psychologic, biochemical and genetic characteristics Goldbourt U, JH
  33. Lancet v.2 Effects of therapy on plasma high-density lipoprotein-cholesterol concen- tration in diebetes melletus Calvert GD;T Mannik;JJ Graham;PH Wise;RA Yeates
  34. 임상화학 이귀녕;김진규
  35. 臨床化學(理論과 實際) 李昌珪
  36. JAMA v.269 Summary of the second report of the National Cholesterol Education Program(NCEP) Expert Panal on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults(Adult Treatment Panel Ⅱ)
  37. 東醫病理學 文濬典(外)
  38. 黃帝內經文句索引 任應秋
  39. 대한동의병리학회지 v.11 no.2 白鼠의 高脂血症에 蒼朴二陳湯이 미치는 影響 金曠洛(外)