• Radiation Oncology Journal
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• v.26 no.2
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• pp.91-95
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• 2008

Purpose: To evaluate the response and survival rate after three-dimensional conformal radiation therapy(3D-CRT) of patients with a solitary sternal relapse of breast cancer. Materials and Methods: Seventeen patients between May 1996 and June 2005 were evaluated with the salvage 3D-CRT treatment of a solitary sternal relapse of breast cancer. The treatment fields included the gross tumor volume with 2 cm margins. The total radiation dose was $35.0{\sim}61.5$ Gy(biologic effective dose of $43.7{\sim}76.9Gy_{10}$ using an $\alpha/\beta$ ratio of 10 Gy), with a daily dose of $1.8{\sim}3.0$ Gy. The tumor response was evaluated by the change in maximum tumor size via follow up CT scans $1{\sim}3$ months after the completion of treatment. Results: An objective tumor response was achieved in all patients, with a complete response in 5 patients and a partial response in 12 patients. The 5-year overall survival rate was 51.9%(median survival time: 27 months), and the most important factor affecting overall survival was the disease-free interval(interval from primary surgery of breast cancer to the development of sternal metastasis): The 5-year overall survival rate was 61.8% for patients with a disease-free interval ${\geq}12$ months and 0.0% for patients with disease-free interval <12 months(p=0.03). Conclusion: The response to 3D-CRT was good in patients with solitary sternal relapse of breast cancer. Particularly, patients with long disease-free interval from primary surgery survived significantly longer than patients with short disease-free interval from primary surgery.

• Investigative Magnetic Resonance Imaging
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• v.17 no.4
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• pp.275-285
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• 2013

Purpose : The objective of this study was to investigate effects of different smoothing kernel sizes on brain tissue-masked susceptibility-weighted images (SWI) obtained from normal elderly subjects using voxel-based analyses. Materials and Methods: Twenty healthy human volunteers (mean $age{\pm}SD$ = $67.8{\pm}6.09$ years, 14 females and 6 males) were studied after informed consent. A fully first-order flow-compensated three-dimensional (3D) gradient-echo sequence ran to obtain axial magnitude and phase images to generate SWI data. In addition, sagittal 3D T1-weighted images were acquired with the magnetization-prepared rapid acquisition of gradient-echo sequence for brain tissue segmentation and imaging registration. Both paramagnetically (PSWI) and diamagnetically (NSWI) phase-masked SWI data were obtained with masking out non-brain tissues. Finally, both tissue-masked PSWI and NSWI data were smoothed using different smoothing kernel sizes that were isotropic 0, 2, 4, and 8 mm Gaussian kernels. The voxel-based comparisons were performed using a paired t-test between PSWI and NSWI for each smoothing kernel size. Results: The significance of comparisons increased with increasing smoothing kernel sizes. Signals from NSWI were greater than those from PSWI. The smoothing kernel size of four was optimal to use voxel-based comparisons. The bilaterally different areas were found on multiple brain regions. Conclusion: The paramagnetic (positive) phase mask led to reduce signals from high susceptibility areas. To minimize partial volume effects and contributions of large vessels, the voxel-based analysis on SWI with masked non-brain components should be utilized.

• Progress in Medical Physics
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• v.26 no.3
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• pp.137-142
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• 2015

We retrospectively analyzed the outcomes in patients who underwent reirradiation for brain metastasis. Twenty-three patients with brain metastases who were initially treated with palliative brain radiotherapy and were retreated with a second course of brain RT between June 2008 and December 2012. WBRT, 3DCRT and SRS were used for brain metastasis. The median dose of the first course of WBRT was 30 Gy (range, 23.4~30 Gy). The dose of the first course 3DCRT for lesion was 30 Gy in 3 Gy per fraction. The median dose of the first course of SRS was 16 Gy in 1 fraction (range, 12~24 Gy). The median dose of the second course of WBRT was 27.5 (range, 12~30 Gy). The median dose of the second course of 3DCRT for lesion was 30 Gy (range, 25~30 Gy). The dose of the second course of SRS was 16 Gy in 1 fraction. The second course of WBRT was administered on radiographic disease progression with symptom in all patients. With median follow-up of 25 months, overall symptom resolution rates were 47.8%. Rate of palliative efficacy was 82.6% including stable disease. The median survival time after initiation of reirradiation was 3.2 months. Median value of KPS prior to reirradiation was 30. Median value of KPS after reirradiation was 60. Reirradiation of brain metastasis maybe feasible and effective in select patients with a good performance status $KPS{\geq}60$ (: ECOG 0~2) prior to reirradiation.

• The Korean Journal of Applied Statistics
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• v.16 no.2
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• pp.455-467
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• 2003

There has been a long debate on the applicability of the chi-square approximation to statistics based on small sample size. Extending comparison results among Pearson chi-square Χ$^2$, generalized likelihood .ratio G$^2$, and the power divergence Ι(2/3) statistics suggested by Rudas(1986), recently developed disparity statistics (BWHD(1/9), BWCS(1/3), NED(4/3)) we compared and analyzed in this paper. By Monte Carlo studies about the independence model of two dimension contingency tables, the conditional model and one variable independence model of three dimensional tables, simulated 90 and 95 percentage points and approximate 95% confidence intervals for the true percentage points are obtained. It is found that the Χ$^2$, Ι(2/3), BWHD(1/9) test statistics have very similar behavior and there seem to be applcable for small sample sizes than others.

• The Journal of the Convergence on Culture Technology
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• v.5 no.3
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• pp.283-288
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• 2019

We propose a method to search for similar images by using outline lines and viewpoints. In the first test, the three-dimensional image, which can't control the motion, has lower search accuracy than the static flat image. For the cause analysis, six specific tropical fish data were selected. We made a 3D graphics of tropical fishes of each kind, and we made 144 image outline lines with 12 stage viewpoints of top, bottom, left and right. Tropical fish by type were collected and sorted by time of search through similar search. Studies have shown that there are many unique viewpoints for each species of tropical fish. To increase the accuracy of the search, a User Interface was created to select the user's point of view. When the user selects the viewpoint of the image, a method of showing the result in consideration of the range of the related viewpoint is proposed.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.3
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• pp.301-307
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• 2011

Turbo blowers are mainly used in refuse collection systems. We discuss blower performance in relation to the angle of the inlet vane installed at the upstream of the blower. The flow characteristics of the components are analyzed by three-dimensional Navier-Stokes analysis and compared to experimental results. A two-stage serially connected turbo blower is introduced to analyze the performance experimentally. Throughout the experimental measurements and the numerical simulation, the distorted inlet velocity generated in the small vane angle reduces the performance of the blower, because of the local leading-edge separation and the resulting non-uniform blade loading. We also perform a detailed flow analysis using the results obtained in the numerical simulation.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.22 no.3
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• pp.85-93
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• 2016

Flower-like zinc oxide (FZnO) was successfully synthesized via a sonochemical process. The chemical structure, morphology, and antimicrobial properties of as- prepared FZnO were investigated. Additionally, pure LDPE and five different LDPE/FZnO composite films were prepared with different FZnO content by using a twin screw extruder. According to the FTIR and SEM analyses, there exists weak interfacial interaction between LDPE and FZnO. Compared with pure LDPE, the LDPE/FZnO composite films showed UV barrier and enhanced antimicrobial activity against Escherichia coli (E. coli) as a Gram-negative micro-organism and Staphylococcus aureus (S. aureus) as a Gram-positive micro-organism. To enhance the interfacial interaction and good dispersion of FZnO into the LDPE matrix, and resultantly to such as UV barrier and antimicrobial properties of LDPE/FZnO composite films as the packaging materials, further efforts are required.

• Polymer(Korea)
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• v.24 no.2
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• pp.201-210
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• 2000

To determine the effect of chain length of linear amine curing agents on the thermal and mechanical properties, standard epoxy resin, diglycidyl ether of bisphenol A (DGEBA) was cured with diethylenetriamine (DETA), triethylenetetraamine (TETA) and tetraethylenepentaamine (TEPA) in a stoichiometrically equivalent ratio. From this work, the effect of linear amine curing agents on the thermal and mechanical properties was significantly influenced by chain length of curing agents. In contrast, the results showed that the DGEBA/DETA system had higher values than the DGEBA/TETA and DGEBA/TEPA system in the density, shrinkage (%), thermal expansion coefficient, tensile modulus, and flexural strength. Whereas the DGEBA/DETA cure system had lower values than the DGEBA/TETA and DGEBA/TEPA cure system in the maximum exothermic temperature, conversion (%), and T$_{g}$. These findings imply that the differences in the maximum conversion about the chain length of curing agents affect the thermal and mechanical properties.s.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.9
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• pp.843-850
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• 2010

This In this paper, we describe the performance characteristics of a turbo blower as a function of the shape of the volute casing: expansion diameter and width of the volute casing. The turbo blower considered in the present study is mainly used in a refuse collection system. The flow characteristics inside the turbo blower were analyzed by a three-dimensional Navier-Stokes solver and compared with experimental results. The distributions of pressure and efficiency obtained by numerical simulation were in good agreement with those determined experimentally. Throughout the numerical simulation of the turbo blower, the blower performance was enhanced by decreasing the local losses in the blade passage and the outlet flow. The efficiency and pressure for the design flow condition were enhanced by about 3% and 2%, respectively, compared to the efficiency and pressure of the reference blower. Detailed flow analysis was performed using the results of the numerical simulation

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.7
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• pp.71-81
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• 2014

In this paper, the performance variations of tri-gate FinFET are analyzed for different fin shapes and source/drain epitaxy types using a 3D device simulator(Sentaurus). If the fin shape changes from a rectangular shape to a triangular shape, the threshold voltage increases due to a non-uniform potential distribution, the off-current decreases by 72.23%, and the gate capacitance decreases by 16.01%. In order to analyze the device performance change from the structural change of the source/drain epitaxy, we compared the grown on the fin (grown-on-fin) structure and grown after the fin etch (etched-fin) structure. 3-stage ring oscillator was simulated using Sentaurus mixed-mode, and the energy-delay products are derived for the different fin and source/drain shapes. The FinFET device with triangular-shaped fin with etched-fin source/drain type shows the minimum the ring oscillator delay and energy-delay product.