• Journal of Life Science
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• v.28 no.10
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• pp.1186-1192
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• 2018

The purpose of this study was to compare the effects of either aerobic exercise or polyphenols supplementation on mRNA expression of endoplasmic reticulum stress in skeletal muscle of high fat diet-induced obese mice. In the study, mice were divided into five groups: (1) NC (normal diet for 16 weeks as a control, n=10), (2) HC (high fat diet for 16 weeks as a control, n=10), (3) H-Re (high fat diet with resveratrol 25 mg/kg supplementation for 16 weeks, n=10), (4) H-Ch (high fat diet with chrysin 50 mg/kg supplementation for 16 weeks, n=10), and (5) HE (high fat diet with aerobic exercise for 16 weeks, n=10). Aerobic exercise was performed on a treadmill for 40~60 min/day at 10~14 m/min, 0% grade, four days/week for 16 weeks. Endoplasmic reticulum stress related genes were measured by real-time polymerase chain reaction. ATF6, PERK, $IRE1{\alpha}$, and BIP/GRP78 mRNA were significantly decreased in HE compared with those in HC (p<0.05). Also, ATF6, $IRE1{\alpha}$, and BIP/GRP78 mRNA were significantly decreased in H-Re compared with those in HC (p<0.05). ATF6 mRNA was significantly decreased in H-Ch compared with that in HC (p<0.05). These findings suggest that aerobic exercise, resveratrol, and chrysin supplementation changed ER stress markers. However, aerobic exercise was most effective on ameliorating the high fat diet induced ER stress markers. Thus, it seems that aerobic exercise might have a more positive effect on skeletal muscle endoplasmic reticulum stress compared with polyphenol supplementation in high fat diet-induced obese mice.

• Journal of the Korean Applied Science and Technology
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• v.35 no.3
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• pp.807-815
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• 2018

This study was investigated the effect of dietary probiotic mixture on blood biomarkers, immune responses, caecal microorganism and productivity in broiler chickens under heat stress (HS). A total of 400 broiler chick males (Ross 308) were divided into four groups of 100 heads each, group C (control, room temperature $25^{\circ}C$), HS (heat stress $33^{\circ}C$) and HSP (HS plus probiotic mixture 500, 750 mg/kg of diet), respectively. Broiler body weight gain, feed intake, feed conversion ratio and immune organ weight increased in the HSP group compared to the HS group. The concentrations of blood IgG and lymphocyte were increased in the HSP group compared to the HS group, and the heterophil:lymphocyte (H:L) ratio, corticosterone concentration and mortality were low. Lactobacillus in the cecum increased in the HSP group compared to the HS group, but was lower in Escherichiacoli (E. coli), coliform bacteria and aerobic bacteria. These results indicate that feeding probitic mixture including three strains such as B. subtilis, S. galilaeus and Sphingobacteriaceae to broiler exposed to heat stress can improve production with lowering mortality by improving immune response and microbial balance.

• Journal of the Korean Society of Radiology
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• v.9 no.6
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• pp.337-342
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• 2015

The one-year-follow-up test of abdomen/pelvis from 10 patients who were scanned more than twice a years were analyzed the radiation dose and image quality depend on the position of the arm retrospectively from January to December in 2013. There were classified two groups, group A was examined with raising an arm on standard position and group B was performed with lowering an arm, respectively. Group A of an average mAs from the first dose amount was shown 11.4% less compared to Group B. And the value of CTDI from Group B also was investigated 11.3% less. To compare the quality comparison of the second image as histogram value, the value of max from both of two groups was measured similarly. However, a big difference was shown from the value of min and SD, the short dose was appeared depends on the position of arm even though Group A was radiated more than Group B. Less exposure to the medical image quality only by working CT scan when the examiner actively raise the arm before the development and testing of high-end equipment introduction of complex algorithms for obtaining an optimized image will be provided to the patient.

• The Journal of Korean Academy of Prosthodontics
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• v.47 no.3
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• pp.342-347
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• 2009

Statement of problem: when using resin for class II restoration, micoleakage by instrumentation can be regarded as the primary negative characteristic. A review of the available literature suggests that using flowable resin as liner to decreased microleakage. Purpose: The aim of this study was to determine the influence of the nanofilled flowable resin lining on marginal microleakage after load cycling in class II composite restoration fillings using nanofiller resin. Material and methods: 24 extracted premolars were prepared with class II cavity. F group was restored the nanofilled resin with the nanofilled flowable resin as liner. NF group was restored the nanofilled resin only. After restoration, an experiment was performed on 2 groups using a 300N load at 104, 105 and 106 cycles. Prior to and before each load cycling, it was gauged length on total marginal microleakage, axial marginal microleakage and buccal, gingival, lingual marginal microleakage. Data were analyzed with the Mann-Whitney test & Kruskal-Wallis test. Results: There were statistically significant differences between 2 groups and between individual groups. (P <.05) The result showed less microleakage in teeth restored by the nanofilled resin, which was lined by the nanofilled flowable resin. Conclusion: There was significant reduction in microleakage when the nanofilled flowable resin lining was placed underneath the nanofilled resin in class II composite restoration fillings.

• Journal of Dental Rehabilitation and Applied Science
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• v.28 no.1
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• pp.47-56
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• 2012

As attractive lips are important component of appealing faces, the study was conducted to investigate the association of mouth-breathing and thickness of lower lips in mouth-breathers and nasal-breathers. The subjects were 436 adolescent patients aged 8~18 years who took cephalometrics. The results were as follows. The ratio of lower lip thickness to that of upper lip thickness in mouth breathing and nasal breathing groups were $1.13{\pm}0.14$, $1.02{\pm}0.14$, respectively. According to subjects' skeletal pattern, the ratio in Class I sample was $1.05{\pm}0.09$. Class II subjects showed $1.20{\pm}0.12$, and Class III showed $0.97{\pm}0.11$. Mouth - breathers had higher lower/upper lip ratio than nasal breathers meaning their lower lips were thicker. Skeletal Class II patients group showed the most thickest lower lips among Class I, II, III subgroups.

• Korean Journal of Plant Resources
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• v.32 no.1
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• pp.29-37
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• 2019

This study was conducted to provide a basic data such as leaf morphological characteristics, total 110 individual trees selected from 11 wild population, for selective breeding. As a result of investigation of the twenty morphological characteristics of the leaf, there were statistically significant differences in all leaf characteristics among the populations. Especially, Mt. Mani population had larger leaf length (LL), width (LW) and area (LAR) than other populations. On the other hand, Mt. Beakwoon and Mt. Duryun had smaller leaf size (LL, LW and LAR) among the populations. Its principal component analysis (PCA) results showed that it represented 72.9% accumulated explanation from three principal component. The characteristics such as leaf area, leaf length and leaf width were highly contributed for classification among populations. According to the cluster analysis, the natural S. alnifolia populations were classified into five groups and Mt. Mani population was different from the other population.

• Journal of Korean Society for Geospatial Information Science
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• v.21 no.3
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• pp.37-46
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• 2013

Similarity measure of catchments is essential for regionalization studies, which provide in depth analysis in hydrological response and flood estimations at ungauged catchments. However, this similarity measure is often biased to the selected catchments and is not clearly explained in hydrological sense. This study applied a type of hydrological similarity distance measure-Flood Estimation Handbook to 25 Geum River catchments, Korea. Three Catchment Characteristics, Area(A)-Annual precipitation(SAAR)-SCS Curve Number(CN), are used in Euclidian distance measures. Furthermore, six index of Flow Duration Curve are applied to clustering analysis of SPSS. The catchments' grouping of hydrological similarity measures suggests three groups (H1, H2 and H3) and the four catchments are not grouped in this study. The clustering analysis of FDC provides four Groups; F1, F2, F3 and F4. The six catchments (out of seven) of H1 are grouped in F1, while Sangyeogyo is grouped in F2. The four catchments (out of six) of H2 are also grouped in F2, while Cheongju and Guryong are grouped in F1. The catchments of H3 are categorized in F1. The authors examine the results (H1, H2 and H3) of similarity measure based on catchment physical descriptors with results (F1 and F2) of clustering based on catchment hydrological response. The results of hydrological similarity measures are supported by clustering analysis of FDC. This study shows a potential of hydrological catchment similarity measures in Korea.

• Journal of Convergence for Information Technology
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• v.12 no.5
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• pp.271-277
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• 2022

In this study, the effect of the anatomical practice extracurricular program on the major efficacy and satisfaction of medical health students was investigated. The research tool used a major efficacy survey, a program satisfaction survey, the major efficacy survey compared and analyzed the improvement before and after participation in anatomy practice and the satisfaction survey between anatomy pictures after completion of the extracurricular program. As a result of comparative analysis between the two groups, the effect on major efficacy was significant after the program progression, and in the case of satisfaction, the satisfaction of the anatomical practice group was higher than that of the anatomical picture group. Through these research results, when operating an anatomical practice extracurricular program, it is thought that operating an anatomical practice program rather than creating an anatomical picture improves the major efficacy and satisfaction score.

• Journal of the Korean Society of Radiology
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• v.14 no.3
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• pp.319-336
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• 2020

The purpose of this study was to compare the outcomes of two interventional methods, overlapping drug-eluting stents (DES) and long DES, for long-term clinical outcomes in patients with acute myocardial infarction (AMI). A total of 438 patients with AMI (65.9±11.0 years, 306 males) from June 2008 to March 2019 who had diffuse long coronary artery lesion, more than 30mm were divided into two groups; group I (overlapped DES group; n=140) and group II (long DES group; n=298). We compared the incidences of major adverse cardiac events [MACEs; cardiac death, myocardial infaction (MI), target lesion revascularization (TLR) and stent thrombosis (ST)] during 12 months between the two groups. Everolimus-eluting stent was more commonly used in group II than in group I (28.1% vs. 51.8% p<0.001). Mean lesion diameter was slightly longer in group II (3.1±0.3mm vs. 3.2±0.3mm, p=0.042), and prevalence of ACC/AHA lesion type C was higher in group I (41.7% vs. 25.4%, p<0.001). Incidences of MACEs during 12 months were higher in group I than group II (18.5% vs. 14.4%, p=0.034). The rates of cardiac death (2.1% vs. 4.4%, p=0.667), MI (5.0% vs. 2.7%, p=0.260) and stent thrombosis rate (0.7% vs. 1.7%, p=0.669) were similar between the two groups. However, TLR rate was higher in group I (10.7% vs. 5.6%, p=0.041). In multivariate logistic regression analysis, presence of diabetes mellitus [Hazard ratio (HR) 2.383, 95% confidence interval (CI) 1.332-4.260, p=0.003] and use of paclitaxel-eluting stent (HR) 2.367, 95% CI 1.371-4.086, p=0.002) were independent predictors of 12-month MACEs, without significant differences in prevalence between the two groups. In AMI patients with diffuse long lesion, TLR rate was higher in the overlapped DES group during 12-month follow-up. Presence of diabetes and use of paclitaxel-eluting stent were independent predictors of MACEs.

• Communications for Statistical Applications and Methods
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• v.19 no.1
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• pp.33-45
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• 2012

The primary interest of drug development studies is to estimate the smallest dose that shows a significant difference from the zero-dose control. The smallest dose is called the Minimum Effective dose(MED). In this paper, we suggest a nonparametric procedure to simultaneously find the MED of each group based on placements. The Monte Carlo simulation is adapted to estimate the power and the family-wise error rate(FWE) of the new procedures with those of discussed nonparametric tests to find MED.