• Title/Summary/Keyword: 분산특성

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Preparation and Characterization of Lipid Nanoparticles Containing Fat-Soluble Vitamin C Derivatives and Gallic Acid (지용성 비타민 C 유도체 및 갈릭산을 함유한 지질나노입자 제조 및 특성)

  • Ji Soo Ryu;Ja In Kim;Jae Yong Seo;Young-Ah Park;Yu-Jin Kang;Ji Soo Han;Jin Woong Kim
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.50 no.2
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    • pp.103-110
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    • 2024
  • Lipid nanoparticles (LNPs) are a stable and an effective system that protects cell-impermeable biologically active compounds such as nucleic acids, proteins, and peptides against degradation caused by subtle environmental changes. This study focuses on developing LNPs encapsulating gallic acid (GA), an antioxidant, to effectively prolong the half-life of tetrahexyldecyl ascorbate (THDC), a oil-soluble vitamin C derivative. These LNPs were synthesized in small, uniform sizes at room temperature and pressure conditions using a microfluidics chip. Compared to liposomes manufactured under high pressure and high temperature conditions through conventional microfluidizers, LNPs manufactured through microfluidics chips had excellent dispersion and temperature stability, and improved skin absorption as well as improved oxidative stability of fat-soluble vitamin C derivatives. Future studies will focus on ex vivo and in vivo evaluations to study skin improvement to further validate these results.

The Effect of Self-Awareness and Other-Awareness on College Life adjustment in Dental Hygiene Students (일부 치위생과 학생의 자기인식 및 타인인식이 대학생활 적응에 미치는 영향)

  • Ji-Young Lee
    • Journal of Korean Dental Hygiene Science
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    • v.6 no.2
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    • pp.161-172
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    • 2023
  • Background: The purpose of this study is to assess the degree of self-awareness, recognition of others, and adaptation to college life of dental hygiene students, and to identify the factors affecting college life adjustment. Methods: The effect size was calculated using the G*power 3.1.9.4 program, based on the data of 191 people who agreed to participate in the questionnaire. Independent samples t-test, one way ANOVA, Post HOC Scheffe, correlation analysis, and multiple regression analysis were conducted to explore the difference and correlation between self-awareness, perception of others, and college life adjustment according to general characteristics. Results: A significant positive correlation was found in self-awareness (r=.301). The highest positive correlations were with social adjustment in both private (r=.340) and public self-awareness (r=.331) (p<0.01). Recognition of others (r=-.051) showed a negative correlation with college life adjustment, though it was not statistically significant. As factors for adapting to college life, private self-awareness (β=.232) and public self-awareness (β=.254) had a positive (+) effect, and internal self-awareness (β=-.205) was found to have a negative (-) effect (p<0.01) Conclusion: The self-awareness and recognition of others among dental hygiene students influence their smooth adjustment to college life. Improvement measures are recommended to enhance adaptability to college life and develop core competencies related to their major

Groundwater Flow Analysis During Excavation for Underground Tunnel Construction (지하 터널 건설을 위한 굴착 시 지하수 유동 분석)

  • Sungyeol Lee;Wonjin Baek;Jinyoung Kim;Changsung Jeong;Jaemo Kang
    • Journal of the Korean GEO-environmental Society
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    • v.25 no.6
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    • pp.19-24
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    • 2024
  • Urban densification has necessitated the development of subterranean spaces such as subway networks and underground tunnels to facilitate the dispersal and movement of populations. Development of these underground spaces requires excavation from the ground surface, which can induce groundwater flow and potentially lead to ground subsidence and sinkholes, damaging structures. To mitigate these risks, it is essential to model groundwater flow prior to construction, analyze its characteristics, and predict potential groundwater discharge during excavation. In this study, we collected meteorological, topographical, and soil conditions data for the city of ○○, where tunnel construction was planned. Using the Visual MODFLOW program, we modeled the groundwater flow. Excavation sections were set as drainage points to monitor groundwater discharge during the excavation process, and the effectiveness of seepage control measures was assessed. The model was validated by comparing measured groundwater levels with those predicted by the model, yielding a coefficient of determination of 0.87. Our findings indicate that groundwater discharge is most significant at the beginning of the excavation. Additionally, the presence of seepage barriers was found to reduce groundwater discharge by approximately 59%.

A Study on the Differences in Awareness of the Social Value of Public Libraries between Public library Users and Non-Users: Focused on Paju City (공공도서관의 사회적 가치에 대한 이용자와 비이용자의 인식 차이에 관한 연구 - 파주시를 중심으로 -)

  • Dong-Geun Oh;Dong-Jo Noh
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.35 no.1
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    • pp.47-71
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    • 2024
  • This study aims to compare the awareness of the social value of public libraries between users and non-users to materialize the abstract concept of social value and, thereby, to present measures that can be applied to the library field. For this purpose, a survey was conducted in person or online for 15 days from May 7, 2023, targeting Paju citizens. Frequency analysis, factor analysis, independent samples t-test, and one-way analysis of variance were conducted on 206 valid response copies using SPSS 25.0. In the results, it is shown that, first, for awareness of the social value of public libraries according to socio-demographic characteristics, there were significant differences depending on age, with in particular, awareness among those in their 10s and 40s being higher than other age groups. For awareness of community development, the awareness of the female group was higher than that of the male group, while, for the awareness according to occupation, it is shown that awareness was highest in the following order: student, others, housewife, self-employed, and office worker. Second, for the awareness of the social value of public libraries, the awareness of the user group was higher than that of the non-user group in all areas. Third, for awareness of the social value of public libraries according to the level of library use, there was no significant difference between groups. In conclusion, it is suggested that measures to encourage non-users to become users, develop new content and services targeting male group and those in their 60s, and 20s, and strengthen community activities are needed to raise awareness of the social value of Paju City public libraries in the future.

A Study on the Effect of Personality Types of College Students on Information Use Behavior and Satisfaction for University Libraries: Focusing on Cultural Learning (대학생의 성격유형이 대학도서관 정보이용행태와 만족도에 미치는 영향 연구: 교양학습을 중심으로)

  • Tae Hee Lee;Woo Kwon Chang
    • Journal of the Korean Society for information Management
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    • v.41 no.3
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    • pp.205-247
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    • 2024
  • The purpose of this study is to investigate how information use behavior and satisfaction appear by personality type for liberal arts learning among college students, and to propose a customized information service plan that can help college students study in university libraries. To this end, a survey was conducted on 169 university students enrolled in C University. The analysis consisted of demographic characteristics, MBTI personality type, information use behavior, satisfaction, and university library service perception survey. Frequency analysis, cross-analysis, multinomial logistic regression, one-way ANOVA, and hierarchical regression analysis were performed on the collected data using the SPSS 29 statistical program. As a result of the study, first, significant results were found in 'preferred information sources', 'information source consideration factors', and 'information collection patterns' according to personality type. Second, there were statistically significant differences in satisfaction according to personality type in 'system utilization ability', 'data selection ability', and 'the degree of recognition of the usefulness of learning activities'. Third, in the relationship between preferred information sources and satisfaction based on personality types and information use behaviors, there appears to be an inverse relationship when the content includes various topics with a lack of academic depth or expertise. However, the preference for 'social media' is positively correlated with 'satisfaction with search results,' as it provides diverse perspectives and viewpoints in liberal education

Experiment to Improve Bioavailability and Oral Absorption of Solubilized Curcumin Using Beta-cyclodextrin and Lysine (Beta-cyclodextrin과 Lysine을 이용한 가용화 커큐민 생체 이용률 및 경구 흡수율 개선 확인 실험)

  • Ye Jin Hwang;Hyeon Woo Kim;Seo Kyung Lee;Ji Hoon Park;Sang Yoon Lee;Jae Seon Kang
    • Journal of Life Science
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    • v.34 no.8
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    • pp.548-557
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    • 2024
  • Curcumin, the primary active compound in Curcumae Radix of the ginger family, exhibits a range of therapeutic effects, including blood sugar regulation, immunoregulation, antioxidant, antibacterial, and antitumor activities. However, its poor water solubility and chemical instability result in suboptimal pharmacokinetics with low oral absorption (0.18%) and bioavailability, thus limiting its efficacy. To overcome these limitations, this study aimed to enhance the oral absorption and bioavailability of curcumin by incorporating lysine and β-cyclodextrin. Following oral administration of solubilized cur- cumin, blood samples were collected to assess the oral absorption rate. Solubilized curcumin showed an approximately 1.55-fold increase in absorption at 120 min compared to its non-solubilized form. Furthermore, intravenous administration followed by blood analysis showed a 25-fold increase in bio- availability at 61 min for the solubilized curcumin compared to the non-solubilized variant. In conclusion, employing lysine for dispersion and stabilization, combined with β-cyclodextrin to enhance solubility, significantly improves curcumin's oral absorption and bioavailability. The results of this experiment are expected to lead to the development of herbal medicines and pharmaceuticals that amplify curcumin's anti-inflammatory, anti-tumor, and blood-sugar-regulation effects.

The Impact of Nursing Students' Empathy, Communication Competence, and Personality on College Adaptation (간호대학생의 공감능력, 의사소통능력 및 인성이 대학적응에 미치는 영향)

  • Seon-Hwa Ban;Se-Hyun Hwang;Koung-Oh Chang
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.5
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    • pp.557-567
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    • 2024
  • This study was a descriptived research study to determine the impact of empathy, communication competence, and personality on college adaptation among nursing students attending a university in City Y. The research method was a self-administered survey targeting 200 nursing students at a university in Y City, and data were collected from April 29, 2024 to May 27, 2024. The research statistical method used was the SPSS/WIN 25.0 statistical program, and was analyzed using t-test, one-way analysis of variance, Pearson correlation, and multiple regression analysis. In the correlation between each variable, college adaptation is related to empathy(r=.522, p<.001), communication competence(r=.557, p<.001), and personality(r=.561, p<.001). And as a result of regression analysis, as a factor affecting the subjects' college adaptation, second-year students(β=-.148, p=.013) had a higher level of college adaptation than first-year students(β=-.297, p<.001). Additionally, the level of college adaptation was high in the order of empathy(β=.295, p<.001), personality(β=.230, p<.001), and communication competence(β=.157, p=.050), and the explanatory power was 47.6%(Adj R2=.476, p<.001). Therefore, in order for nursing students to adapt to college, various psychological and emotional supports must be provided at the school and department level, and various customized programs that can improve empathy, communication competence, and personality should be developed and applied by considering the characteristics of nursing students by grade.

A study on the Change in the Characteristics of Fashion Design Created through the Use of Fashion Flat Drawing and Midjourney (패션 도식화와 미드저니의 활용을 통하여 생성한 패션디자인의 특징 변화 연구)

  • Park, Keunsoo
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.5
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    • pp.397-406
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    • 2024
  • Today, in the field of contemporary fashion design, AI is being actively utilized as a new design tool, leading to a new paradigm of collaboration between designers and AI. This study is about a method for developing integrated fashion design through collaboration between human designers and AI. The purpose of this study is to analyze the visual and formative characteristics and changes of fashion design images generated using the AI generation program Midjourney, thereby expanding the understanding and utilization methods of AI image generation programs in fashion design development. The results of this study are as follows. First, Midjourney has the characteristic of relying more on the characteristics of the existing image used rather than the command when creating the image. It also creates new images by distributing and applying the design through an eclectic interaction between the costume and the image background. By excluding the names of fashion items from the commands, you can generate images that can give you more diverse ideas. Second, Midjourney initially expressed clothing colors using colors used in fashion schematics in color creation, and gradually expanded to various color series. Third, there is a kind of compromise between color and design when Midjourney creates an image, and accordingly, by specifying and limiting the image background and clothing colors, more diverse and advanced fashion design images can be created.

A Study on Factors Influencing College life adjustment of Nursing Students who experienced the COVID-19 pandemic (COVID-19 팬데믹을 경험한 간호대학생의 대학생활적응 영향 요인에 관한 연구)

  • Yang, Seung Ae
    • Journal of Internet of Things and Convergence
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    • v.10 no.4
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    • pp.77-88
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    • 2024
  • This study aims to identify the degree of the major selection motivation, self-efficacy, resilience, social support, academic stress, and college life adjustment of nursing students who experienced the COVID-19 pandemic, and to identify the correlations between variables and factors affecting college life adjustment. The data of this study was collected from May 14, 2024 to June 20, 2024 through a Google online questionnaire targeting 182 nursing students in Seoul and the metropolitan area and descriptive statistics, Student's t-test, one-way ANOVA, Pearson's Correlation, and linear multiple regression were conducted using SPSS Statistics 25.0. The results of the difference analysis by general characteristics showed that there was a significant difference in college life adjustment by age (F=10.602, p=.000) and grade (t=-2.334, p=.021). College life adjustment showed a significant positive (+) correlation with major selection motivation (r=.581, p<.010), self-efficacy (r=.551, p<.010), resilience (r=.699, p<.010), and social support (r=.557, p<.010), but a significant negative (-) correlation with academic stress (r=-.495, p<.010). The variables that affected college life adjustment were identified as resilience (𝛽=.366, p<.01), academic stress (𝛽=-.183, p<.05), motivation for choosing a major (𝛽=.168, p<.05), and age (𝛽=.117, p<.05), and the explanatory power for college life adjustment was 56.7%. The finding of this study can be used as basic data for developing strategies to enhanced the college life adjustment of nursing students.

Studies on the selection in soybean breeding. -II. Additional data on heritability, genotypic correlation and selection index- (대두육종에 있어서의 선발에 관한 실험적연구 -속보 : 유전력ㆍ유전상관, 그리고 선발지수의 재검토-)

  • Kwon-Yawl Chang
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.3
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    • pp.89-98
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    • 1965
  • The experimental studies were intended to clarify the effects of selection, and also aimed at estimating the heritabilities, the genotypic correlations among some agronomic characters, and at calculating the selection index on some selective characters for the selection of desirable lines, under different climatic conditions. Finally practical implications of these studies, especially on the selection index, were discussed. Twenty-two varieties, determinate growing habit type, were selected at random from the 138 soybean varieties cultivated the year before, were grown in a randomized block design with three replicates at Chinju, Korea, under May and June sowing conditions. The method of estimating heritabilities for the eleven agronomic characters-flowering date, maturity date, stem length, branch numbers per plant, stem diameter, plant weight, pod numbers per plant, grain numbers per plant and 100 grain weight, shown in Table 3, was the variance components procedures in a replicated trial for the varieties. The analysis of covariance was used to obtain the genotypic correlations and phenotypic correlations among the eight characters, and the selection indexes for some agronomic characters were calculated by Robinson's method. The results are summarized as follows: Heritabilities : The experiment on the genotype-environment interaction revealed that in almost all of the characters investigated the interaction was too large to be neglected and materially affected the estimates of various genotypic parameters. The variation in heritability due to the change of environments was larger in the characters of low heritability than in those of high heritability. Heritability values of flowering date, fruiting period (days from flowering to maturity), stem length and 100 grain weight were the highest in both environments, those of yield(grain weight) and other characters were showed the lower values(Table 3). These heritability values showed a decreasing trend with the delayed sowing in the experiments. Further, all calculated heritability values were higher than anticipated. This was expected since these values, which were the broad sense heritability, contain the variance due to dominance and epistasisf in addition to the additive genetic variance. Genotypic correlations : Genotypic correlations were slightly higher than the corresponding phenotypic correlations in both environments, but the variation in values due to the change of environment appeared between grain weight and some other characters, especially an increase between grain weight and flowering date, and the total growing period(Table 6). Genotypic correlations between grain weight and other characters indicated that high seed yield was genetically correlated with late flowering, late maturity, and the other five characters namely branch numbers per plant, stem diameter, plant weight, pod numbers per plant and grain numbers per plant, but not with 100 grain weight of soybeans. Pod numbers and grain numbers per plant were more closely correlated with seed yields than with other characters. Selection index : For the comparison and the use of selection indexes in the selection, two kinds of selection indexes were calculated, the former was called selection index A and the later selection index B as shown in Table 7. Selection index A was calculated by the values of grain weight per plant as the character of yield(character Y), but the other, selection index B, was calculated by the values of pod numbers per plant, instead of grain weight per plant, as the character of yield'(character Y'). These results suggest that selection index technique is useful in soybean breeding. In reality, however, as the selection index varies with population and environment, it must be calculated in each population to which selection is applied and in each environment in which the population is located. In spite of the expected usefulness of selection index technique in soybean breeding, unsolved problems such as the expense, time and labor involved in calculating the selection index remain. For these reasons and from these experimental studies, it was recognized that in the breeding of self-fertilized soybean plants the selection for yield should be based on a more simple selection index such as selection index B of these experiments rather than on the complex selection index such as selection index A. Furthermore, it was realized that the selection index for the selection should be calculated on the basis of the data of some 3-4 agronomic characters-maturity date(X$_1$), branch numbers per plant(X$_2$), stem diameter(X$_3$) and pod numbers per plant etc. It must be noted that it should be successful in selection to select for maturity date(X$_1$) which has high heritability, and the selection index should be calculated easily on the basis of the data of branch numbers per plant(X$_2$), stem diameter(X$_3$) and pod numbers per plant, directly after the harvest before drying and threshing. These characters should be very useful agronomic characters in the selection of Korean soybeans, determinate growing habit type, as they could be measured or counted easily thus saving time and expense in the duration from harvest to drying and threshing, and are affected more in soybean yields than the other agronomic characters.

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