• Development and Reproduction
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• v.7 no.2
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• pp.69-80
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• 2003

The zebrafish(Danio rerio) is a pre-eminent vertebrate model system for clarification of the roles of specific genes and signaling pathways in development. We show examples of positional cloning in two developmental mutants in zebrafish. headless: The severe head defects in headless(hdl) mutants are due to a mutation in T-cell factor-3(Tcf3). Loss of Tcf3 function in the hdl mutant reveals that Hdl represses Wnt target genes. The results provide genetic evidence that a component of the Wnt signaling pathway is essential in vertebrate head formation and patterning. mind bomb: Reduced lateral inhibition in mind bomb(mib) mutants permits too many neural precursors to differentiate as neurons. Positional cloning of mib revealed that it is a gene in the Notch pathway that encodes a ubiquitin E3 ligase. Mib interacts with the intracellular domain of Delta to promote its internalization. The results suggest a model for Notch activation where the Delta-Notch interaction is followed by endocytosis of Delta and transendocytosis of the Notch extracellular domain by the signaling cell.

• Journal of the Korean Society for information Management
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• v.25 no.4
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• pp.205-226
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• 2008

The success of social networking sites (SNSs) may depend on many factors. Continuance use of SNSs is one of these. Especially, in the Web environment where users can leave one service with a single mouse click, maintaining existing members cost much time and efforts. Without continuance use of SNSs, SNS-based service would not create any value. This study focused on identifying factors influencing users' continuance intention in SNSs. Based on relevant literature review, six influencing factors were initially identified. They were reputation, relational capital, knowledge quality, compatibility, personalization, and satisfaction. Web-based questionnaire survey was conducted and a total of 325 usable responses were collected. Reliability test and two rounds of exploratory factor analyses resulted in identifying five factors. The relationship between the factors and the continuance intention was tested by using multiple regression analyses. The analyses revealed that satisfaction was the most significant factor. Knowledge quality and relational capital also had significant effects while reputation and personalization did not have significant effect on continuance intention. Instead, reputation and personalization showed significance in influencing satisfaction.

• 한국신재생에너지학회:학술대회논문집
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• 2008.05a
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• pp.406-407
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• 2008

지난 8년간 세계 태양광 시장은 연평균 40% 이상 성장하여 2006년 200억 불 규모로 초고속성장을 지속하고 있으며 2010년 1,300억 불, 2012년에는 2,000억 불에 이를 것으로 전망되며, 2015년에는 메모리반도체 시장규모를 추월할 것으로 예상된다. 국내 태양광 산업은2004년 이후 적극적인 기술개발 및 보급정책의 결과 2008년 현재 산업 기반이 조성되었으며 수출산업으로 전환단계에 있다. 태양광 분야는 반도체/디스플레이 시장과 같이 기술력과 자금력을 보유한 소수의 기업이 이익을 독점하는 구조로서 2007년 상위 5개국이 전체 생산량의 85%를 차지하는 실정이다. 이것은 우리가 조기에 기술 및 규모를 확보하지 못할 경우 추후 경쟁에서 매우 불리함을 인식하고 실리콘 소재 기술력의 국산화 및 박막형 태양전지의 양산화 조성 등 세부기술의 분류를 나열하고 2-3년 이내에 상용화 가능한 요소기술, 4-5년 이내에 양산구동력을 구축할 수 있는 핵심기술, 10년 이내에 글로벌경쟁력을 갖출 수 있는 원천기술력을 발굴하고 정부-기업-연구소(대학)가 공동의 지원책을 강구하여 융합된 미래 글로벌 기술력을 확보한 신성장 동력원으로 가치창출 요소를 발굴할 필요성이 있다.

• Korean Journal of Construction Engineering and Management
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• v.18 no.4
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• pp.17-26
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• 2017

The sustainable growth of Construction Management(CM) market depends on clients'acceptance from positive project outcomes of CM services. Achieving the positive outcomes requires CM firms'competency and efforts. Equally, it is critical to understand and overcome barriers of CM performance, which cause inefficiencies and under-performance of CM services. The objective of the study is to identify and discuss the barriers of CM performance during pre-construction stages in private CM projects based on the FMEA technique. Major findings basically suggest that clients and CM firms have roles to play, individually and collaboratively, in order to improve CM performance by eliminating performance barriers.

• International Commerce and Information Review
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• v.2 no.1
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• pp.149-158
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• 2000

[ $\Box$ ]무역업계는 인터넷의 발전에 따라 급속히 사이버화 하고 있는 무역환경에 적극적으로 대응하기 위해 사이버무역의 도입과 활성화를 위한 움직임을 급속히 확대하고 있는 것으로 나타났다. - 조사대상업체의 절반이 넘는(51.8%) 업체들이 자사제품 홍보, 거래선 발굴, 오퍼 및 거래협상 둥 각종 무역업무에 인터넷을 이용하고 있는 것으로 나타났다. - 그러나 무역업계의 사이버무역 활용은 아직 초기단계 수준으로, 이용업체의 절반이상(57.3%)은 작년(1999년) 이후에 처음으로 사이버무역을 시작하였으며 사이버무역에 의한 수출비중도 10% 미만(1999년: 8.8%)의 낮은 수준인 것으로 조사되었다. - 반면, 향후 무역업계의 사이버무역 도입 확대와 수출비중 증가는 가속화될 것으로 나타나, 2000년에는 사이버무역 비중이 전년보다 두 배 이상 늘어난 18.7%에 달할 것으로 예상되었으며, 특히 중소기업의 경우 사이버무역 비중이 상대적으로 대기업보다 커질 것으로 전망되었다. $\Box$ 무역업계가 사이버무역을 도입하는 이유로는 "해외시장 개척효과" 때문이라는 응답이 가장 많았으며, 다음으로 "수출업무 신속화률 통한 인건비 절감"과 "광고비의 절약" 등의 효과를 염두에 두고 있는 것으로 나타났다. - 따라서 여러 수출단계 중에서도 "해외거래선 발굴"， "해외시장정보의 수집", "자사 제품의 해외 홍보" 등 주로 시장개척과 마케팅단계에서 사이버무역이 가장 많이 활용되고 성과도 큰 것으로 나타났다. - 시장개척과 마케팅을 위하여 약 40%의 무역업체가 무역거래 알선 사이트를 이용하고 있으며 특히 중소기업의 활용이 두드러진 것으로 파악되었다. - 반면, 사이버무역 활동이 애로를 겪고 있는 수출단계로는 "대금결제, 물류 유통", "신용조회", "거래계약 체결" 등의 순으로 조사되었는데, 이는 국제적 인증제도의 미비, 신용조사에 대한 공신력 부족 둥이 주된 요인인 것으로 분석되었다. $\Box$ 한편, 무역업계는 사이버무역의 필요성과 활용성과에 대해 긍정적인 인식을 갖고 있으나, 사이버무역을 활성화하는데 필요한 인프라로서 사이버 무역 전문인력이나 인터넷 통신환경 등은 아직 만족할 만한 수준이 못 되는 것으로 조사되었다. - 사이버인력 부문에서는 무역업무 종사자 중 인터넷 활용직원의 비율이 50%가 되지 않는 업체가 전체의 절반을 넘고 있으며, 특히 중소기업의 인터넷 활용 직원의 비율이 대기업에 비해 낮은 것으로 나타났다. - 향후 무역업체가 10명의 무역인력을 채용한다고 가정할 경우, 평균 4.5명을 사이버무역 전문인력으로 채용할 계획이라고 밝히고 있으며, 중소기업(4.7명)이 대기업(3.4명)보다 사이버무역 전문인력에 대한 수요가 더 큰 것으로 나타나 이에 대한 대책이 시급한 것으로 파악되었다. - 인터넷 전용선 설치비율도 전체적으로 40%대에 그치고 있으며, 특히 중소기업의 경우 전용선 이용비율(38.5%)이 대기업(80%)의 절반에도 못미치는 열악한 수준에 있어 중소기업의 사이버 무역이용에 하나의 걸림돌이 되고 있는 것으로 조사되었다. $\Box$ 사이버 무역활성화를 위해 가장 시급한 과제로는 "사이버무역 전문인력 확충을 위한 체계적 교육 및 훈련제공"과 "사이버무역 관련법규 및 제도의 마련"으로 나타나, - 정부나 유관기관이 앞장서서 사이버무역 관련 교육프로그램의 개발, 자격시험제도의 도입 등과 아울러 대외무역법 둥 관련법률 및 제도를 정비해 줄 것을 무역업계에서 기대하는 것으로 지적되었다.

• Korean Journal of Comparative Education
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• v.27 no.3
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• pp.101-127
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• 2017

The purpose of this study is to analyze how the debates on learning and learning outcomes in global education agendas have changed and to understand the discourses and issues about learning under the agendas, and finally based on the understanding, to know what is the implication we should take in international education development cooperation in Korea. To do this, this study critically analyzed 1) what is the main features and directions, and 2) the method and limitation in handling learning concept on three major global education forums which are Jomtien global education forum in 1990, Dakar in 2000, and Incheon in 2015. Major finding shows that there are little learning concept discussed in Jomtien and Dakar forums and in SDGs education agenda, learning is vaguely defined and discussed and there are problems of too much focus on learning outcomes itself and absence of study on proper assessment system. Major lessons and implications for international education development cooperation could be stated that postcolonial perspectives and learner centered approaches is required in developing countries's education ecology. And continuous support for sustainable development for learners' capacity should be underlined. We needs to focus on developing software not hardware from the first of educational ODA. Finally, it is needed to embed within pedagogical approaches.

• The Journal of the Korea Contents Association
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• v.12 no.9
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• pp.226-233
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• 2012

Purpose: The purpose of this study was to develop and analyze the effectiveness of an education program counseling manual (EPCM) for community-based visiting nurses. Methods: Seventy-eight of community-based visiting nurses was enrolled in this study. Data were collected using structured questionnaires and analyzed using descriptive statistics, the ${\chi}^2$-test, and the paired t-test in SPSS version 18.0. Results: Nurses had higher mean scores for counselor activity self-efficacy: skill self-efficacy, session management self-efficacy and counseling challenges self-efficacy, after EPCM than before EPCM. Significant differences were found after applying the EPCM. Conclusion: The results of this study indicate that the EPCM is effective at improving counselor self-efficacy of community-based visiting nurses.

• Design Convergence Study
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• v.13 no.5
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• pp.131-145
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• 2014

Considering the number of population commuting from Gyeonggi to Seoul, the development of the bus system is relatively slow. There are many problems to be solved but it has been overlooked, leaving the users in discomfort. The goal of this research is to improve the current system to satisfy the unmet needs, using HCI methods, which is composed of five steps, including Define, Find, Analyze & Synthesize, Ideation, Develop. In Define, we recruited the interviewees using the extreme user method to find their needs. In Find, we proceeded 'be the customer', shadowing for background research and in-depth interview. In Analyze & Synthesis, we analyzed the customer needs and clustered to similar needs to draw useful ideas. After that we suggested sophisticated ideas based on design principles from previous stage and visualized in user scenarios and mock-ups. Overall, the research suggests with text message service, informative light service and mobile application to improve the existing bus station.

• Journal of Life Science
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• v.19 no.5
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• pp.587-592
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• 2009

A dramatic morphological change of embryos occurs at peri-implantation. Maternal and embryonic cross-talk during this period, initiated by signals from embryo(s), provides signals for maternal recognition of pregnancy and establishing and maintaining the pregnancy. However, the cellular, biochemical and genetic processes that direct embryo remodeling in mammalian species are not well studied or understood. In order to identify potential genes responsible for morphological change and cross-talk between embryo and uterus, an initial EST analysis was performed. A catalog of expressed genes (Transcriptome) from the d12 peri-implanting porcine embryos was constructed. Six clones were chosen from the initial ESTs for elucidation of their expression patterns during embryogenesis in early pregnancy. A number of these genes demonstrated unique expression profiles in a tissue, cell-type, and temporal fashion, indicating dynamic regulation of embryonic and endometrial gene expressions at different stages of pregnancy. Cross-talk between the embryo and endometrium of the pregnant uterus has provided a suitable micro-environment for the embryo's rapid and dramatic morphological changing process at the peri-implantation stage.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.163-177
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• 2016

This study suggests a method for making a system of basic materials for the restoration of the 3X3 Kan central hall remains of a Buddhist temple from the Joseon Dynasty. Because there are both an extant hall and remains from the Joseon Dynasty, the basic material can be constructed through comparison with the floor plan. Multi-step comparisons were found to be the most suitable example for restoration. For this study, five parts of the 3x3 Kan remains were compared with 70 extant halls for a case study. For the first comparison, the limit of collection makes four examples in the whole examples. There are many relationships with the area and the length ratio of the front to the side as the comparison articles, so there are examples that satisfied both comparison articles. However, there is little relationship between the length ratio of the front Eokan to the front Hyeopkan and the length ratio of side Eokan to the side Hyeopkan. The construction method of the basic material shows the possibility of expansion with various directions that have pros and cons.