• Title/Summary/Keyword: 반영비

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Assessment of Abnormality in Skeletal Muscle Metabolism in Patients with Chronic Lung Desease by $^{31}P$ Magnetic Resonance Spectroscopy ($^{31}P$ 자기 공명분석법을 이용한 만성 폐질환 환자에서의 골격근대사 이상에 관한 연구)

  • Cho, Won-Kyoung;Kim, Dong-Soon;Lim, Tae-Hwan;Lim, Chae-Man;Lee, Sang-De;Koh, Youn-Suck;Kim, Woo-Sung;Kim, Won-Dong
    • Tuberculosis and Respiratory Diseases
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    • v.44 no.3
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    • pp.583-591
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    • 1997
  • The functional derangement of skeletal muscles which may be attributed to chronic hypoxia has been accepted as a possible mechanism of exercise impairment in patients with chronic obstructive pulmonary disease (COPD). The metabolic changes in skeletal muscle in patients with COPD are characterized by impaired oxidative phosphorylation, early activation of anaerobic glycolysis and excessive lactate and hydrogen ion production with exercise. But the cause of exercise limitation in patients with chronic lung disease without hypoxia has not been known. In order to evaluate the change in the skeletal muscle metabolism as a possible cause of the exercise limitation in chronic lung disease patients without hypoxia, we compared the muscular metabolic data of seven male patients which had been derived from noninvasive $^{31}P$ magnetic resonance spectroscopy(MRS) with those of five age-matched normal male control persons. $^{31}P$ MRS was studied during the sustained isometric contraction of the dominant forearm flexor muscles up to the exhaustion state and the recovery period. Maximal voluntary contraction(MVC) force of the muscle was measured before the isometric exercise, and the 30% of MVC force was constantly loaded to each patient during the isometric exercise. There were no differences of intracellular pH (pHi) and inorganic phosphate/phosphocreatine(Pi/PCr) at baseline, exhaustion state and recovery period between two groups. But pHi during the exercise was lower in patients group than the control group (p < 0.05). Pi/PCr during the exercise did not show significant difference between two groups. These results suggest that the exercise limitation in chronic lung disease patients without hypoxia also could be attributed to the abnormalities in the skeletal muscle metabolism.

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Development and Application of Training Program for RI-Biomics Manpower through Analysis of Educational Demands (교육수요 분석을 통한 RI-Biomics 전문인력 양성 프로그램 개발 및 적용)

  • Shin, Woo-Ho;Park, Tai-Jin;Yeom, Yu-Sun
    • Journal of The Korean Association For Science Education
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    • v.35 no.1
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    • pp.159-167
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    • 2015
  • RI-Biomics is a promising radiation convergence technology that combines radiation with bio science as new growth power technology. Many developed countries are focusing active support and constant exertion to dominate the RI-Biomics market in advance. In order to achieve global leadership in the RI-Biomics field, we need more highly advanced technologies and professional manpower. In fact, we have less manpower compared to technology we currently hold. In this study, we established a basic infrastructure to train professional manpower in the RI-Biomics field by developing/operating optimum training program through expert interviews and survey. The developed program has four organized sections to understand overall procedure of RI-Biomics. To evaluate our training program, we performed test operations with eight students who have a major related to RI-Biomics for three weeks in KARA (Seoul) and KAERI (Jung-eup). In detail, radioisotope usage and safety management were conducted for one week as basic course, RI-Biomics application technology was conducted for two weeks as professional course. To verify performance results of training program, we conducted to journal research, daily reports, and survey on participants. The results show a high level of satisfaction with training programs and continuous intention of involvement in our program. We also need to develop an intensive course to train high-quality human resources and to operate training program continuously. This training program will be used as basic materials for the development of RI-Biomics curriculum for university. Hence, we will expect that our training program contributes in training a professional manpower and develop RI-Biomics technology.

Case Study of Teaching Practices of Biology Teachers with and without Research Experience in Evolution Education (진화 교육 연구 경험 유무에 따른 생명과학 교사의 교수 실행 사례 연구)

  • Ko, Yuseon;Cha, Heeyoung;Lim, Mili
    • Journal of The Korean Association For Science Education
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    • v.37 no.4
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    • pp.747-761
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    • 2017
  • The purpose of this study is to analyze differences in the teaching practices of biology teachers according to their awareness of the importance of evolution. For this purpose, two teachers who experienced study of evolution and recognized its importance, along with two teachers with no experience in evolution education in the comparison group, were included in the sample. To observe teaching practices, two classes each on biological evolution and non-evolution were selected, recorded and transcribed. The content analyzed included the teachers' view on evolution education and teachers' evolution concepts reflected in teaching practice. As a result, the level of understanding of the teachers' evolution concept was unrelated to teachers' awareness of the importance of evolution. Instead, each teacher would not feel the need for religious beliefs or awareness of the importance of evolution to have a negative impact on the awareness of the importance of evolution. Inexperienced teachers tend to reject the retraining opportunities to recognize the importance of evolution. In addition, inexperienced teachers were only superficially aware of the evaluation and improvement of evolution presented in textbooks and curricula. In actual teaching practice analysis, inexperienced teachers' utilizing ratio of the evolution key concept was higher than that of experienced teachers. Only experienced teachers were aware of the misconceptions presented in their execution and described the causes that appear in these misconceptions. Teachers who recognized the importance of evolution were widely using the key concepts of evolution, as well as more practical in preventing the misconceptions related to evolution forms. It indicates that biology teachers who do not realize the importance of evolution in biology education need to experience explicit and practical education programs as well as instructional materials on evolution.

Statistical Analysis on Microcrack Length Distribution in Tertiary Crystalline Tuff (제3기 결정질 응회암에서 발달하는 미세균열의 길이 분포에 대한 통계적 분석)

  • Park, Deok-Won
    • The Journal of the Petrological Society of Korea
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    • v.20 no.1
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    • pp.23-37
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    • 2011
  • The scaling properties on the length distribution of microcrack populations from Tertiary crystalline tuff are investigated. From the distribution charts showing length range with 15 directional angles and five groups(I~V), a systematic variation appears in the mean length with microcrack orientation. The distribution charts are distinguished by the bilaterally symmetrical pattern to nearly N-S direction. The whole domain of the length-cumulative frequency diagram for microcrack populations can be divided into three sections in terms of phases of the distribution of related curves. Especially, the linear middle section of each diagram of five groups represents a power-law distribution. The frequency ratio of linear middle sections of five groups ranges from 46.6% to 67.8%. Meanwhile, the slope of linear middle section of each group shows the order: group V($N60{\sim}90^{\circ}E$, -2.02) > group IV($N20{\sim}60^{\circ}E$, -1.55) > group I($N60{\sim}90^{\circ}W$, -1.48), group II($N10{\sim}60^{\circ}W$, -1.48) > group III($N10^{\circ}W{\sim}N20^{\circ}E$, -1.06). Five sub-populations(five groups) that closely follow the power-law length distribution show a wide range in exponents( -1.06 - -2.02). These differences in exponent among live groups emphasizes the importance of orientation effect. In addition, breaks in slope in the lower parts of the related curves represent the abrupt development of longer lengths, which is reflected in the decrease in the power-law exponent. Especially, such a distribution pattern can be seen from the diagram with $N10{\sim}20^{\circ}E,\;N10{\sim}20^{\circ}W$ and $N60{\sim}70^{\circ}W$ directional angles. These three directional angles correspond with main directions of faults developed around the study area. The distribution chart showing the individual characteristics of the length-cumulative frequency diagrams for 15 directional angles were made. By arraying above diagrams according to the categories of three groups(A, B and C), the differences in length-frequency distributions among these groups can be easily derived. The distribution chart illustrates the importance of analysing microcrack sets separately. From the related chart, the occurrence frequency of shorter microcracks shows the order: group A > group B > group C. These three types of distribution patterns could reveal important information on the processes occurred during microcrack growth.

A Theoretical Review of Basin Storage Coefficient and Concentration Time Using the Nash Model (Nash 모형을 이용한 유역 저류상수 및 집중시간의 이론적 검토)

  • Yoo, Chul-Sang
    • Journal of Korea Water Resources Association
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    • v.42 no.3
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    • pp.235-246
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    • 2009
  • This study theoretically reviews the basin storage coefficient and concentration time using the Nash model, a simple unit hydrograph theory. First, the storage coefficient and concentration time of Nash instantaneous unit hydrograph (IUH) are derived based on their definitions, whose characteristics as well as their relationship are also reviewed. Additionally, several empirical equations of storage coefficient and concentration time commonly used in Korea are evaluated by comparing them with those for the Nash IUH. Major results of this study are summarized as follows. (1) The concentration time of Nash IUH is approximately linearly proportional to the number of linear reservoirs, but the storage coefficient non-linearly to the square root. That is, if increasing the number of linear reservoirs by four times, the concentration time becomes also increased by about four times, but the storage coefficient only about two times. This result has a special meaning to understand the effect of basin subdivision on the concentration time and storage coefficient. (2) The storage coefficient and concentration time of Nash IUH are not independent each other, so their independent estimation does not make any physical sense. As the concentration time among the two is more sensitive to the number of linear reservoirs, which should be estimated first, then the storage coefficient considering the concentration time estimated. (3) Empirical equations of concentration time can be divided into two groups, one following the linear channel theory and the other not, whose equation forms are also found to be very similar. This result indicates that the characteristic factors dominating the concentration time are very similar, indicating the possibility of its regionalization over a basin with consistent equation forms. (4) Those for storage coefficient like the Russell formulae are found to consider the physical characteristics of a basin, so their unreasonable applications could sufficiently be excluded.

Ecological Characteristics of Korean Red Pine (Pinus densiflora S. et Z.) Forest on Mt. Nam as a Long Term Ecological Research (LTER) Site (국가장기생태연구 장소로서 구축된 남산 소나무림의 생태적 특성)

  • Lee, Chang-Seok;Cho, Yong-Chan;Shin, Hyun-Cheol;Lee, Choong-Hwa;Lee, Seon-Mi;Seol, Eun-Sil;Oh, Woo-Seok;Park, Sung-Ae
    • Journal of Ecology and Environment
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    • v.29 no.6
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    • pp.593-602
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    • 2006
  • Species composition, spatial distribution of major species, diameter and height classes distribution, and species diversity were .analyzed in the Korean red pine (Pinus densiflora, hereafter referred as pine) forest in the permanent quadrats, which were designed for Long Term Ecological Research (LTER). Collected data were compared with those from the other areas including urban center (Mt. Inwang and Hongneung) and boundary areas (Mts. Acha, Bukhan, Bulam, Cheonggye, Daemo, and Surak), and natural areas (Mts. Seolak, Songni, and Wolak) to clarify the ecological characteristics of pine forest on Mt. Nam. Species composition of pine forest on Mt. Nam showed a similarity with those of urban center but did a little and big differences with those on urban boundary and natural areas, respectively. Such differences that pine forest on Mt. Nam showed, were usually due to Styrax japonicus, Sorbus alnifolia, Oplismenus undulatifolius, Ailanthus altissima, Ageratina altissima and so on, which showed higher coverage there. Predicted from diameter and height classes distribution of tree species, pine forest on Mt. Nam showed a possibility to be replaced by a S. japonica. Considered that this replacer species is not only a sub-tree but also shade intolerant, such successional trend could be interpreted as a sort of retrogressive succession. Those on urban boundary and natural areas showed a difference by displaying probabilities to be maintained as themselves as an edaphic climax or succeeded to oak forests. Species diversity of pine forest on Mt. Nam was lower than those in urban boundary and natural areas due to excessive dominance of several species, which led to different species composition from the other areas. Plants, which produced the differences, were species that flourishes in the polluted industrial area (S. japonica and S. alnifolia), favors the disturbed site (O. undulatifolius), and exotic species (A. altissima and Eupatorium rugosum). Those results reflects that pine forest of Mt. Nam was exposed on severe environmental pollution and excessive human interferences.

Dynamic forecasts of bankruptcy with Recurrent Neural Network model (RNN(Recurrent Neural Network)을 이용한 기업부도예측모형에서 회계정보의 동적 변화 연구)

  • Kwon, Hyukkun;Lee, Dongkyu;Shin, Minsoo
    • Journal of Intelligence and Information Systems
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    • v.23 no.3
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    • pp.139-153
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    • 2017
  • Corporate bankruptcy can cause great losses not only to stakeholders but also to many related sectors in society. Through the economic crises, bankruptcy have increased and bankruptcy prediction models have become more and more important. Therefore, corporate bankruptcy has been regarded as one of the major topics of research in business management. Also, many studies in the industry are in progress and important. Previous studies attempted to utilize various methodologies to improve the bankruptcy prediction accuracy and to resolve the overfitting problem, such as Multivariate Discriminant Analysis (MDA), Generalized Linear Model (GLM). These methods are based on statistics. Recently, researchers have used machine learning methodologies such as Support Vector Machine (SVM), Artificial Neural Network (ANN). Furthermore, fuzzy theory and genetic algorithms were used. Because of this change, many of bankruptcy models are developed. Also, performance has been improved. In general, the company's financial and accounting information will change over time. Likewise, the market situation also changes, so there are many difficulties in predicting bankruptcy only with information at a certain point in time. However, even though traditional research has problems that don't take into account the time effect, dynamic model has not been studied much. When we ignore the time effect, we get the biased results. So the static model may not be suitable for predicting bankruptcy. Thus, using the dynamic model, there is a possibility that bankruptcy prediction model is improved. In this paper, we propose RNN (Recurrent Neural Network) which is one of the deep learning methodologies. The RNN learns time series data and the performance is known to be good. Prior to experiment, we selected non-financial firms listed on the KOSPI, KOSDAQ and KONEX markets from 2010 to 2016 for the estimation of the bankruptcy prediction model and the comparison of forecasting performance. In order to prevent a mistake of predicting bankruptcy by using the financial information already reflected in the deterioration of the financial condition of the company, the financial information was collected with a lag of two years, and the default period was defined from January to December of the year. Then we defined the bankruptcy. The bankruptcy we defined is the abolition of the listing due to sluggish earnings. We confirmed abolition of the list at KIND that is corporate stock information website. Then we selected variables at previous papers. The first set of variables are Z-score variables. These variables have become traditional variables in predicting bankruptcy. The second set of variables are dynamic variable set. Finally we selected 240 normal companies and 226 bankrupt companies at the first variable set. Likewise, we selected 229 normal companies and 226 bankrupt companies at the second variable set. We created a model that reflects dynamic changes in time-series financial data and by comparing the suggested model with the analysis of existing bankruptcy predictive models, we found that the suggested model could help to improve the accuracy of bankruptcy predictions. We used financial data in KIS Value (Financial database) and selected Multivariate Discriminant Analysis (MDA), Generalized Linear Model called logistic regression (GLM), Support Vector Machine (SVM), Artificial Neural Network (ANN) model as benchmark. The result of the experiment proved that RNN's performance was better than comparative model. The accuracy of RNN was high in both sets of variables and the Area Under the Curve (AUC) value was also high. Also when we saw the hit-ratio table, the ratio of RNNs that predicted a poor company to be bankrupt was higher than that of other comparative models. However the limitation of this paper is that an overfitting problem occurs during RNN learning. But we expect to be able to solve the overfitting problem by selecting more learning data and appropriate variables. From these result, it is expected that this research will contribute to the development of a bankruptcy prediction by proposing a new dynamic model.

Analysis of User Satisfaction on the City Squares in Seoul - Focused on Grand Public Place - (서울 소재 도시광장에 대한 이용자 만족도 분석 - 중심 대 광장을 대상으로 -)

  • Lee, Jung-A;Lee, Hyung-Sook;Choi, Yun-Eui;Chon, Jin-Hyung
    • Journal of the Korean Institute of Landscape Architecture
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    • v.40 no.3
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    • pp.42-50
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    • 2012
  • City squares are public open spaces which are closely related to the peoples daily lives. Most squares are located in the center of the city, and they are usually used for community gatherings and they are suitable for open markets, music concerts, political rallies, and other events. City squares also play an important role as a grand public place operating in multi functions that require involvement of more people. The purpose of this study is to examine satisfaction on the spatial components, characteristics, and the user satisfaction in City Squares. The slady also analyzed the relationship between the satisfaction about spatial components, characteristics and it also shows that the user satisfaction is followed. This study sites are made in 3 grand public places in the center of Seoul including the Seoul plaza, Cheonggye Plaza, and Gwanghwarnun Square. Data were analyzed using several statistical methods such as descriptive statistics, factor analysis, ANOVA, correlation and regression. Results of the study are as follows: First, factor analysis carried out to extract the various factors of satisfaction on the sites; spatial components, usability, amenity/security, and spatial characteristics. User satisfaction concerning usability factor was higher than the satisfaction of the other factors. This result represented that the slady sites play an important role to the public open spaces in the city. Second, users showed high user satisfaction to study sites, and user satisfaction rate toward the Gwanghwarnun Square is the highest because of its facility planuing. Finally, user satisfactim was strongly correlated on the usability factor of spatial planning. Also, the significant correlations between the user satisfaction and the other factors such as spatial components, security, and spatial characteristics of spatial planning are presented. Results of this study can help guide the planning and management of the city square as a public open space based on the understanding of user perception and satisfaction.

Temporal and spatial variations of SST and Ocean Fronts in the Korean Seas by Empirical Orthogonal Function (경험 직교함수 분석에 의한 한반도 주변해역의 해수면온도 및 수온 전선의 시${\cdot}$공간 변화)

  • Yoon, Hong-Joo;Byun, Hye-Kyung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • v.9 no.1
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    • pp.397-402
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    • 2005
  • In the Korean seas, Sea Surface Temperature (SST) and Thermal Fronts (TF) were analyzed temporally and spatially during 8 years from 1993 to 2000 using NOAA/AVHRR MCSST As the result of EOF method applying SST, the variance of the 1st mode was 97.6%. It is suitable to explain SST conditions in the whole Korean seas. Time coefficients were shown annual variations and spatial distributions were shown the closer to the continent the higher SST variations like as annual amplitudes. The 2nd mode presented higher time coefficients of 1993, 94, and 95 than those of other years. Although the influence is a little, that tan explain EININO effort to the Korean seas. TF were detected by Sobel Edge Detection Method using gradient of SST. Consequently, TF were divided into 4 fronts; the Subpolar Front (SPF) dividing into the north and south part of the East sea , the Kuroshio Front (KF) in the East China Sea (ESC), the South Sea Coastal Front (SSCF) in the South sea, and the Tidal Front in the West sea. TF located in steep slope of submarine topography. The distributions of 1st mode in SST were bounded in the same place, and these results should be considered to influence of seasonal variations. To discover temporal and spatial variations of TF, SST gradient values were analyzed by EOF. The time coefficients fo the 1st mode (variance : 64.55%) showed distinctive annual variations and SPF, KF, and SSCF was significantly appeared in March. the spatial distributions of the 2nd mode showed contrast distribution, as SPF and SSCF had strong'-'value, where KF had strong'+'value. The time of'+'and'-'value was May and October, respectively. Time coefficients of the 3rd mode had 2 peaks per year and showed definite seasonal variations. SPF represented striking'+'value which time was March and October. That was result reflected time of the 1st and 2nd mode. We can suggest specific temporal and spatial variations of TF using EOF.

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Using Effective Temperatures to Determine Safety Cultivation Season in Direct Seeding Rice on Dry Paddy (작물생육 유효기온 출현시기를 이용한 건답직파 벼의 지역별 안전작기 설정)

  • 최돈향;윤경민;윤성호;박무언
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.42 no.6
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    • pp.666-672
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    • 1997
  • Twenty years' daily mean air temperature data was used to calculate the critical early seeding date(CESD), the optimum heading date(OHD), the critical late heading date for stable ripening(CHDR) and the critical late ripening date(CLRD) for rice seeded on dry paddy in different agroclimatic zones in Korea. The CESD was defined as the first day with mean air temperature of 13$^{\circ}C$, and the OHD as the first day of the 40 consecutive days with mean air temperature of 22$^{\circ}C$ or above after heading. The CHDR was defined as the date after which the cumulative daily mean air temperature would be at least 76$0^{\circ}C$. Lastly, the CLRD was defined as the last day when daily mean air temperature remains above 15$^{\circ}C$. This information was used for the estimation of periods from the earliest date of seeding to optimum heading date, the latest possible date of heading and the latest possible date of ripening in respective regions. For instance, in Suwon, those respective periods mentioned were found to be 104days, 124days, and 165days.

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