• Review of KIISC
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• v.26 no.4
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• pp.41-46
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• 2016

전통적으로 바이오인식기술은 출입국심사(전자여권, 승무원 승객 신원확인), 출입통제(도어락, 출입통제 근태관리), 행정(무인민원발급, 전자조달), 사회복지(미아찾기, 복지기금관리), 의료(원격의료, 의료진 환자 신원확인), 정보통신(휴대폰 PC 인터넷 인증), 금융(온라인 뱅킹, ATM 현금인출) 등 다방면에서 폭넓게 보급되어 실생활에서 널리 활용되고 있다. [그림1]은 신체적 특징(Physiological biometrics)과 행동적 특징(Behavioral biometrics)을 이용한 사용자 인증기술인 바이오인식기술의 유형과 함께 각 기술별 보안취약점(괄호 안 빨강색글자)을 나타내고 있다. 최근 들어, 모바일 지급결제서비스 ATM 인출기 인터넷전문은행 등과 같은 핀테크 분야에서 비대면 인증기술로 바이오인식기술이 각광을 받기 시작했다. 한편, 가짜지문 등 기존의 신체적 특징을 이용한 바이오인식기술의 위변조 위협에 대한 우려 존재함에 따라 뇌파 심전도 근전도 맥박 등 살아있는 사람의 행동적(신체의 기능적) 특징을 이용한 생체신호를 이용하여 비대면 인증기술로서 활용하기 위하여 주요 선진국에서 차세대 바이오인식 기술개발이 가속화되고 있는 추세이다.[1] 또한, 이러한 생체신호는 최근에 삼성전자, LG전자, 애플 등에서 스마트워치를 통해 심장박동수를 측정하고 스마트폰을 통하여 모바일 지급결제, 헬스케어 등과 같은 IoT 모바일 융복합 응용서비스에 활용될 전망이다. 본고에서는 뇌파 심전도(심박수)와 같은 생체신호를 측정하는 스마트워치 밴드형 의복형 또는 패치형태의 웨어러블 디바이스와 같은 생체신호센서, 생체신호 인증기술 및 관련표준화 동향을 고찰해 보기로 한다. 국내외 관련기술과 표준화 동향을 면밀히 분석하여 지난 2015년 5월29일에 발족한 국내외 전문가그룹인 KISA"모바일 생체신호 인증기술 표준연구회"(이하 KISA 표준연구회)가 구심점이 되어 한국형 생체신호를 이용한 차세대 텔레바이오인식기술에 대한 연구개발과 국내외 표준화 추진에 박차를 가할 계획이다.

• Electronics and Telecommunications Trends
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• v.27 no.5
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• pp.64-72
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• 2012

물질의 상태를 알기 위해 사용되는 센서 기술은 전기적 신호와 정보 등을 감지하는 전자 기술뿐만 아니라 생물학을 포함한 바이오 기술과 나노 기술과의 융합을 통해 진화하고 있다. 이러한 진화는 아이폰을 시작으로 하는 IT 산업의 변화를 이끌 뿐만 아니라, 헬스케어 분야를 중심으로 빠르게 적용되고 있는 기술로써 첨단기술의 상징으로 자리매김하고 있다. 이미 많은 사람들이 알고 있는 유비쿼터스 사회에서 꼭 필요한 스마트 센서로써의 현주소를 파악하기 위해서 산업동향과 국 내외 주요 연구결과물들을 살펴보고, 향후 발전방향을 예측해 보고자 한다.

• Journal of Biomedical Engineering Research
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• v.29 no.5
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• pp.337-342
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• 2008

To date, many researchers have developed a variety of biosensors to detect the biomolecular interactions. Recently, electrochemical biosensors have been attracting great interest as one of key technologies in a ubiquitous healthcare (U-healthcare) system since they are highly sensitive and feasible to miniaturize. Here we overview the current electrochemical biosensors based on strip-type, nanowire/nanotube, field effect transistor (FET), and nanogap electrode.

• Information Systems Review
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• v.25 no.3
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• pp.163-177
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• 2023

This research aims to identify key initiatives and a policy approach to support the industrialization of the sector. The research collected a total of 91,873 news data points relating to healthcare between 2013 to 2022. A total of 20 topics were derived through topic modeling analysis, and as a result of time series regression analysis, 4 hot topics (Healthcare, Biopharmaceuticals, Corporate outlook·Sales, Government·Policy), 3 cold topics (Smart devices, Stocks·Investment, Urban development·Construction) derived a significant topic. The research findings will serve as an important data source for government institutions that are engaged in the formulation and implementation of Korea's policies.

• Journal of the Korean Society of Food Culture
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• v.36 no.1
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• pp.130-142
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• 2021

This study examined the antioxidative and lipid accumulation inhibitory effects of 14 plants from Mongolia and Myanmar on 3T3-L1 and HepG2 cells. The total phenolic and flavonoid contents (TPC and TFC) of 14 plant extracts were measured, and the antioxidative activities were analyzed using DPPH, ABTS, FRAP, and ORAC. After measuring the pancreatic lipase levels and performing the thiobarbituric acid assay, the degree of lipid accumulation was determined by lipid (Oil Red O) staining and triglyceride assay in 3T3-L1 and HepG2 cells. M. paniculate (259.43 mgGAE/g) and C. benghalensis (130.78 mgNAE/g) had the highest TPC and TFC, respectively, among the 14 plants. R. acicularis Lindl. had the highest antioxidant activity in DPPH. The ABTS, FRAP, and ORAC results showed that the antioxidant activity of 11 species was higher than that of the positive control. The pancreatic lipase inhibitory effect of C. angustifolium Scop. was reduced to 23.65% at 0.1 mg/mL, and the level of lipid peroxidation of C. abrorescens Lam. was 0.63 nmol/mg. Five selected plants inhibited the lipid accumulation and triglyceride content, respectively, in 3T3-L1 and HepG2 cells. These results provide scientific evidence for developing functional foods using 14 plants from Mongolia and Myanmar, which have antioxidant activities and lipid accumulation reduction effects.

• Korean Journal of Clinical Pharmacy
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• v.31 no.1
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• pp.21-26
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• 2021

Background: Pharmacogenomics is the study of how genetic mutations in patients affect their response to drugs. Pharmacogenomic studies aim to maximize drug effects and minimize adverse drug events. The Food and Drug Administration and the European Medicine Agency published guidelines for pharmacogenetics in 2005 and 2006, respectively; the Korean Ministry of Food and Drug Safety followed suit in 2015. Methods: This study analyzed pharmacogenomic information in the Korean Ministry of Food and Drug Safety's integrated drug information system to evaluate whether domestic pharmaceutical products reflect the current research on pharmacogenomic differences. Results: In June 2020, the Korean pharmacogenomic database contained genomic data on 90 compounds. Of these, 45 compounds were classified as "Antineoplastic and immunomodulating agents." The other 45 non-antineoplastic agents were in the following categories: Anti-infectives, Mental & behavior disorder, Hormone & metabolism related diseases, Cardiovascular system, Skin & subcutaneous tissue disease, Genito-urinary system and sex hormones, Blood and blood forming organs, Nervous system, Alimentary tract and metabolism, Musculo-skeletal system, and Other conditions including the respiratory system. In addition, 30 additives unrelated to the main ingredient were associated with genetic precautions. Conclusion: This study showed that antineoplastic and immunomodulating agents accounted for half the drugs associated with pharmacogenetic information. For antitumor and immunomodulatory drugs, genomic tests were recommended depending on the indication; this was in contrast to genomic testing recommendations for non-antineoplastic medications. Genomic tests were rarely requested or recommended for non-antineoplastic medications because the relationships between genotype and efficacy among those drugs were relatively weak.

• Journal of the Korean Regional Science Association
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• v.39 no.2
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• pp.19-30
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• 2023

This study analyzed intra-regional disparities by using the concentration index of industrial organization theory. And the range of study is 11 cities in Chungcheongbuk-do province. This study aims to clarify the characteristics of the intra-regional disparities by using concentration ratio(CR) and Herfindahl-Hirschman Index. After the review of previous studies, we intend to study the intra-regional disparities using these two indexes. Target is the bio-health industry that all povinces in South Korea want to develop competitively. In addition the analysis was conducted by dividing the bio-health industry into four detailed fields(pharmaceuticals, medical devices, health functional foods, and cosmetics). These fields are based on the results of the city and county competitiveness-enhancing industry. The research results derived the intra-regional disparities index based on sales, the number of workers, and R&D expenses by detailed field. As a result it was confirmed that the strengths according to the detailed fields differed by region. It can be used as basic data in establishing differentiated industrial development strategies for each region in the future.

• Journal of The Korean Society of Integrative Medicine
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• v.12 no.2
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• pp.111-119
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• 2024

Purpose : This study aimed to demonstrate the effects of visiting cognitive activities using brain training on cognition, subjective memory complaints and depression among elderly participants residing in community living in Gwangmyeong city. Methods : Over a 14-month period (October 2022 to December 2023), four brain training instructors visited the homes of older adults and conducted the intervention using a brain training kit. The participants included 32 elderly individuals aged 65 years and older, who were living in Gwangmyeong city. The assessments were conducted by an occupational therapist, a nurse and a social worker at the Gwangmyeong dementia relief center. These assessments included the following the subjective memory complaints questionnaire (SMCQ), short geriatric depression scale-Korean (SGDS-K), a cognitive impairment screening test (CIST), the consortium to establish a registry for Alzheimer's disease-Korean (CERAD-K). The participants were divided into three groups (A: 20-30 points, B: 10-19 points, C: 1-9 points) based on the CIST score. For data analysis, descriptive statistics and wilcoxon signed-rank test were performed using SPSS 24.0, and the statistical level was at a=.05. Results : The results of the intervention showed that the SMCQ score of group A improved significantly (p<.05), the CIST score of group B also improved significantly (p<.05). However, the SGDS-K score of group C improved, but did not demonstrate statistical significance (p=.080). Conclusion : The visiting cognitive activities using brain training produced significant effects on cognition, depression, and subjective memory disorders, depending on the cognitive level of the elderly participants. In the future, it will be necessary to demonstrate the effects according to cognitive level in various aspects with more elderly people.

• Information Systems Review
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• v.26 no.1
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• pp.367-383
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• 2024

Korea faces challenges in securing technical talent due to low birth rates and an aging population. To bridge labor market gaps, tailored education programs through universities are crucial. Although Program for Industrial needs-Matched Education (PRIME) encouraged developing industrial-university education courses, a few universities have the opportunities and the courses development is often depending on capability of a professor. Furthermore, administrative issues hinder progress. This study proposes streamlining administrative processes and leveraging technology to meet industry demands. Active collaboration between academia and industry can enhance education and benefit both employees and students.

• Korean Journal of Medicinal Crop Science
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• v.28 no.6
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• pp.445-454
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• 2020

Background: Culturing wild ginseng adventitious root using plant factory technology provides genetic safety and high productivity. This production technology is drawing attention in the fields of functional raw materials and product development. The cultivation method using elicitors is key technology for controlling biomass and increasing secondary metabolites. Methods and Results: Elicitor treatments using methyl jasmonate, pyruvic acid, squalene, β-sistosterol were performed to amplify total ginsenosides (Rb1, Rc, Rb2, Rb3, and Rd) of cultured wild ginseng adventitious root. Thereafter, fermentation and steaming processes were performed to convert total ginsenosides into minor molecular ginsenosides (Rg3, Rk1, and Rg5). The result indicated that methyl jasmonate minimizes the reduction in fresh weight of cultured wild ginseng adventitious root and maximizes total ginsenosides (sum of Rb1, Rc, Rb2, Rb3, and Rd). Ginsenoside conversion results showed a maximum degree of conversion of 131 mg/g. Conclusions: In this study, we demonstrated that the optimal elicitor treatment method increased the content of total ginsenosides, while the steaming and fermentation processing method increased the content of minor ginsenosides.