• Title/Summary/Keyword: 김훈

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Evaluation of the Physiological Activity and Identification of the Active Ingredients of Crab Apple (Malus prunifolia Borkh.) Extracts (꽃사과(Malus prunifolia Borkh.) 추출물의 생리활성 평가 및 활성 성분의 규명)

  • Shin, Hyun Young;Kim, Hoon;Jeong, Eun-Jin;Kim, Hyun-Gyeong;Lee, Kyung-Haeng;Bae, Yun-Jung;Kim, Woo Jung;Lee, Sanghyun;Yu, Kwang-Won
    • The Korean Journal of Food And Nutrition
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    • v.34 no.5
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    • pp.477-486
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    • 2021
  • To utilize Malus pruniforia Borkh. as a functional material, cold-water (CW), hot-water (HW), and 70% ethanol (EtOH) extracts were prepared, and their antioxidant and anti-inflammatory activities were compared. The antioxidant activity of the HW extract evaluated by ABTS and DPPH radical scavenging and FRAP activity was significantly effective. The total polyphenol content of the HW extract was also higher by 15.5±0.7 mg GAE/g extract compared to other extracts. The EtOH extract showed significantly decreased TNF-α (39.8%), IL-6 (65.5%), and NO (34.9%) levels in RAW 264.7 cells compared to the LPS-induced control group. The levels of IL-6 (21.1%) and IL-8 (19.3%) were significantly decreased by treatment of EtOH extract in HaCaT keratinocytes induced with TNF-α and IFN-γ. The UHPLC-MS results indicated that the EtOH extract might have chlorogenic acid and phlorizin as the major compounds. This was validated using HPLC-DAD, which showed that the EtOH extract had higher levels of chlorogenic acid and phlorizin (1,185±58 and 470±10 ㎍/g extract, respectively). In conclusion, the present study suggested that the anti-inflammatory activity of the EtOH extract was more effective than the CW and HW extracts, and chlorogenic acid and phlorizin could be used as indicator compounds and functional substances.

An Empirical Study on Factors Affecting Organizational Survival of Entertainment Corporations (조직생존요인에 관한 실증분석 : 엔터테인먼트 기업을 대상으로)

  • Kim, Hun;Kim, Jung Hoon
    • Review of Culture and Economy
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    • v.20 no.1
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    • pp.129-161
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    • 2017
  • Korea's entertainment industry laid its foundation in the early 2000s when global popularity of South Korean soap operas increased in Japan. K-pop has been recently leading the popularity in China. However, many Korean entertainment businesses are dying out. This study reviews factors influencing business survival for 42 chosen corporations listed in the Korea Stock Exchange based on organizational ecology. When all of the variables are analyzed at the same time, long period of public offering and high wages and global sales ratio positively affect business survival. When the individual variables are separately analyzed, long period of public offering and CEO incumbency and high wages and global sales ratio positively affect business survival. Meanwhile, size of businesses do not affect the survival. The results of this study imply that policies to help businesses list an entertainment corporation in the Korea Stock Exchange, increase sales and reciprocity with other culture are needed. Laws and institutions for evaluating intangible asset value should be improved. The results also suggest that a corporation should carefully consider change of CEO and make the best use of the popularity of Korean culture to increase global sales and pay competitive wages to attract professionals.

Performance Evaluation of Rough Rice Low Temperature Drying Using Heat Pump (열펌프를 이용한 벼의 저온건조성능평가)

  • Kim, Hoon;Han, Jae-Woong
    • Food Engineering Progress
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    • v.13 no.4
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    • pp.308-313
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    • 2009
  • This study was conducted to design and fabricate a heat pump that can produce some weather conditions similar to those of the dry season of the rough rice in Korea, and to investigate basic performances of the apparatus. During the drying test, the amount of energy consumption and drying characteristics were measured at four different temperature levels ranging between 20$^{\circ}C$ and 50${^{\circ}C}$. In the psychrometric chart, the freezing capacity and refrigerant circulation ratio of the heat pump were 173 kJ/kg and 49.6 kg/hr, respectively. Therefore, coefficient of performance was 5.5, which was superior to that of refrigerant R-22 (4.0) in standard refrigeration cycle. In addition, the time to reach target drying temperature (30${^{\circ}C}$) and relative humidity (40%) were 6 minutes and 7 minutes, respectively. Temperature differences between the drying temperature and the rice were 1.5${^{\circ}C}$ and 8.5${^{\circ}C}$ at the drying temperatures of 21.9${^{\circ}C}$ and 48.7${^{\circ}C}$, respectively. This result demonstrated that the increased temperature of the rice in the drying section decreased sufficiently in the tempering section. At the drying temperatures of 21.9, 30.7 38.8, and 48.7${^{\circ}C}$, drying rates were 0.29, 0.61, 0.85, and 1.26%/hr, respectively, which were similar to those of commercial dryer. In addition, the amounts of energy consumption were 325, 667, 692, and 776 kJ/kg, respectively. These results showed that this dryer saved up to 86% of energy consumption compared with the commercial dryer, which uses 4,000-5,000 kJ/kg of fossil fuel.

Anti-oxidative and Immunomodulating Activities of Solvent Extracts from Broccoli (Brassica oleracea) Sprouts (브로콜리 새싹 용매 추출물의 항산화 및 면역조절 활성)

  • Koh, Jong-Ho;Kim, Hoon;Hwang, Jong-Hyun;Yu, Kwang-Won
    • The Korean Journal of Food And Nutrition
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    • v.32 no.1
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    • pp.1-10
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    • 2019
  • In order to examine the functionality of broccoli sprout (Brassica oleracea, BS), solvent extracts were prepared and their anti-oxidative and immunomodulating activities were compared with those of broccoli (B). EtOH extracts (E) were potently higher than hot-water extracts (HW) in the antioxidant contents and radical scavenging activity. In particular, the total polyphenolic contents in addition to ABTS and DPPH radical scavenging activity were significantly higher in EtOH extract of broccoli sprout (BS-E; 9.15 mg GAE/g, 4.52 mg AEAC/g, and 1.14 mg AEAC/g) compared with that of broccoli (B-E; 7.83 mg GAE/g, 3.63 mg AEAC/g, and 0.97 mg/AEAC/g). Whereas, total flavonoid content was significantly higher in B-E (1.60 mg QE/g) than BS-E (1.43 mg QE/g). Anti-inflammatory activity was investigated using LPS-induced cell line model at a concentration of $10{\sim}100{\mu}g/mL$, in which all solvent extracts of both broccoli sprouts and broccoli were not toxic to RAW 264.7 cell lines. In anti-inflammatory activity of broccoli sprouts, EtOH extracts also showed significantly more potent activity than hot-water extracts in all sample concentrations tested. In addition, BS-E ($100{\mu}g/mL$) inhibited nitric oxide (NO) and IL-6 production to 60.9% and 68.9% compared with the LPS inflammation group (without extracts), whereas B-E inhibited 49.6% and 54.9%. On the other hand, in immunostimulating activity by splenocytes and macrophages, hot-water extract showed significantly higher activity than EtOH extract. Especially, BS-HW stimulated the splenocyte proliferation (1.2-fold against saline group) and IFN-${\gamma}$ production (264.39 pg/mL) at $100{\mu}g/mL$, and the production of IL-6 (1.33-fold), IL-12 (1.09-fold) and TNF-${\alpha}$ (1.49-fold) from macrophages was also significantly enhanced over broccoli. In conclusion, broccoli sprouts showed more potent anti-oxidative, anti-inflammatory and immunostimulating activity than broccoli, suggesting the possibility of using broccoli sprouts as functional food materials.

Phases of the Discourse Through the Way of Remembering the Japanese Invasion of Korea in 1592 (기억방식을 통해 본 임진왜란의 서사 양상)

  • Eum, Yeong-Cheol;Park, Eun-Mi
    • The Journal of the Korea Contents Association
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    • v.18 no.11
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    • pp.161-170
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    • 2018
  • In this paper, the aspects of recollection discourse during the Japanese Invasion of Korea in 1592 are discussed. As a research method the dialectic of oblivion is used. The results of the study are like these: first, the hero discourse of Lee Soon-Sin was the center of the discourse of the Japanese invasion of Korea in 1592 until the 20th century. In the two books Jingbirok and A War Diary written at that time, the subjective and objective description of the war was essential. However, it has a limit that it can't describe the real situation of the war that the people and the soldiers went through, as it focuses on Lee Soon-Sin's inner thoughts. Second, in the 21st century The Song of Sword written by Kim Hoon deals with the inner mind of Lee Soon-Sin in monologue unlike the usual hero discourse. Although as we can see in the records about the marine righteous army, people centered discourse description of the war shows a different way of discourse about the Imjin War. The movie, Myeongryang directed by Kim Han-Min tries to modify the way of remembering the war and presents the real heroes were the people and Lee Soon-Sin was a additional character in the war by showing a lot of battle scenes in the sea. The truth of history can't be found by only researching the recorded materials. As cultural texts dealing with the way of remembering the war, the novel shows a struggling individual not a hero and the movie focuses on that people's active participation led the victory of the war.

Change in Biodiversity and Community Structures in Agricultural Fields depending on Different Farming Methods (농법 차이에 따른 농경지 생태계의 생물 다양성 및 군집 구조의 변화)

  • Kim, Hoon;Kim, Kyo-Jin;Sun, Yan;Jo, Young-Ju;Kim, Tae-Yeon;Moon, Myung-Jin
    • Korean Journal of Organic Agriculture
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    • v.26 no.4
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    • pp.687-706
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    • 2018
  • Organic agriculture is well known to be not only affecting the physical and chemical status of the soil but also closely connected to the biodiversity through complex community structure and ecological interactions. Current study monitored and analyzed the invertebrate biodiversity of organic and conventional paddy fields and upland fields from April, 2017 to August, 2017. Total of 680 species (with 14,371 individuals) were confirmed - more number of species were identified at the organic agriculture practicing fields. According to the various indices analysis, organic paddy field showed about 40% higher diversity index, while organic upland field showed about 10% higher diversity index. Richness index at organic paddy field was 60% higher compared to conventional paddy field, while organic upland field showed 40% higher value. Dominance and evenness index at conventional agriculture practicing fields were low, which possibly indicate at least partial dominance phenomenon. Hemipteran, dipteran and aranean species showed highest diversity in all fields, while dipteran, hemipteran, aranean and coleopteran species had highest diversity in conventional agriculture practicing fields.

Pharmaceutical Drug Poisoning after Deregulation of Over the Counter Drug Sales: Emergency Department Based In-depth Injury Surveillance (편의점 안전상비의약품 판매 허용 이후 치료 약물 중독)

  • Kim, Sung Ho;Kim, Hyunjong;Lee, Ji Sook;Park, Junseok;Kim, Kyung Hwan;Shin, Dong Wun;Kim, Hoon;Park, Joon Min;Jeon, Woochan
    • Journal of The Korean Society of Clinical Toxicology
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    • v.16 no.2
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    • pp.141-148
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    • 2018
  • Purpose: The Korean government approved selected nonprescription drugs (Over-The-Counter drug; OTC drug) to be distributed in convenience stores from 15. Nov. 2012. This study examined the changes in the incidence and the clinical outcome of acute pharmaceutical drug poisoning after the deregulation of OTC drug sales. Methods: This study analyzed the data of Emergency Department based Injury In-depth Injury Surveillance (EDIIS), Korea Centers for Disease Control and Prevention, from 2011 to 2014. The following items were examined: age, gender, intention, alcohol association, pharmaceutical drugs resulting acute poisoning, the clinical outcomes in emergency department, and the admission rate of intensive care unit (ICU). This is a retrospective cross section observational study. Results: A total of 10,162 patients were subject to pharmaceutical drug poisoning. Acute poisoning by acetaminophen and other drugs were 1,015 (10.0%) and 9,147 (90.0%) patients, respectively. After the deregulation of OTC drug sales, acute poisoning by other drugs increased from 4,385 to 4,762 patients but acute poisoning by acetaminophen decreased from 538 to 477 patients (p<0.05). The rate of admission of acetaminophen poisoning increased from 36.1% (194/538) to 46.8% (223/477). The admission rate to the ICU by acetaminophen poisoning increased from 4.6% (25/538) to 11.3% (54/477) after the deregulation of OTC drug sales (p<0.05). Conclusion: Since the deregulation of OTC drugs sales, pharmaceutical drug poisoning has increased but acetaminophen poisoning has decreased. The rate of hospitalization and ICU admission by pharmaceutical drug poisoning with or without acetaminophen has also increased.

The characteristics of mild head injuries in preschool-age children fall: a retrospective observational study (학령전기 소아에서 추락으로 인한 경증 두부손상의 특징에 대한 후향적 관찰 연구)

  • Sung, Min Suk;Lee, Ji Sook;Jeon, Woochan;Park, Junseok;Kim, Kyung Hwan;Shin, Dongwun;Kim, Hoon;Park, Joon Min;Kim, Hyunjong
    • Journal of The Korean Society of Emergency Medicine
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    • v.29 no.5
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    • pp.423-429
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    • 2018
  • Objective: Falling is a common cause of head injury in preschool aged children. We investigated the characteristics of mild head injuries caused by falling and the association between body weight and occurrence of traumatic brain injuries (TBI). Methods: This retrospective observational study was conducted on head-injured preschool-aged children that visited the emergency department from January 2012 to December 2015. Characteristics such as age, sex, weight, free fall height, floor type, and presence of TBI, as defined as cerebral hemorrhage or skull fracture, were investigated. We calculated body weight percentiles by calibrating age and weight and categorized them into four quartile ranges. We grouped all included cases into two groups according to the presence of TBI. The characteristics of the two groups were compared by using chi-square test, and the association with TBI was investigated by using binomial logistic regression. Results: A total of 701 children were included, and TBI was observed in 95 children. Children with TBI were younger. The proportion of children with TBI was higher in the third and fourth quartiles of the body weight group as well as according to soft floor and fall from high height (${\geq}1m$). The odds of soft floor being associated with TBI was higher than the odds for hard floor (odds ratio, 2.734; 95% confidence interval [CI], 1.597-4.680). The odds of high height (${\geq}1m$) being associated with TBI was higher than that for low height (odds ratio, 2.306; 95% CI, 1.155-4.601), and the odds ratio for the weight percentile group was 1.228 (95% CI, 1.005-1.499). Conclusion: Prevalence of TBI after falling in preschool-aged children might be associated with high fall-height and body weight quartiles.

Bioactive Compounds, Anti-Oxidant Activities and Anti-Inflammatory Activities of Solvent Extracts from Centella asiatica Cultured in Chungju (충주산 병풀 용매추출물의 활성성분과 항산화 및 항염증 활성)

  • Shin, Hyun-Young;Kim, Hoon;Jeong, Eun-Jin;Kim, Jeung-Eun;Lee, Kyeong-Haeng;Bae, Yun-Jeong;Yu, Kwang-Won
    • The Korean Journal of Food And Nutrition
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    • v.33 no.6
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    • pp.692-701
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    • 2020
  • Centella asiatica (CA) has been widely used as herbal plants. It is a valuable resources. The aim of the present study was to evaluate physiological activities of solvent extracts from CA cultivated in Chungju, Korea (Good tiger care). After preparing water (cold-water, CA-WE; hot-water, CA-HWE) and EtOH extracts (50% EtOH, CA-50E; 70% EtOH, CA-70E), their total polyphenol, flavonoid, and triterpenoid contents, and anti-oxidant activities, and anti-inflammatory activities were examined and compared. CA-70E showed the most potent anti-oxidant activity based on ABTS radical scavenging activity and reducing ability assays, while CA-50E and CA-70E showed the highest DPPH radical scavenging activity. Among major triterpenoid glycosides present in CA, madecassoside and asiaticoside contents were found to be the highest in CA-70E, and madecassic acid and asiatic acid were the highest in CA-50E. In LPS-stimulated RAW 264.7 cells, CA-70E showed the highest TNF-α inhibitory activity, although CA-50E and CA-70E similarly inhibited nitric oxide production. Ethanol extracts significantly inhibited IL-6 and IL-8 production more than water extracts using TNF-α/IFN-γ-stimulated HaCaT cells, indicating its better inhibitory against skin inflammation. Therefore, Chungju-CA EtOH extract, especially 70% EtOH extract, has high physiologically active ingredients and potent anti-oxidant and anti-inflammatory activities, suggesting its industrial application as a functional material.

A Study on the Image of a Nurse in Korean Modern Novels (한국 현대소설에 나타난 간호사 이미지 연구)

  • Hwang, Hyo Sook
    • Journal of Digital Convergence
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    • v.20 no.4
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    • pp.725-735
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    • 2022
  • This study analyzed how the literary works embodying nurses accommodate various discourses about nurses and reproduce them in literature. The subject of analysis is a Korean modern novel featuring a nurse, and 29 works were selected from 1927 to 2016. The analysis method is the content analysis of the novel among the qualitative research methods. The unit of analysis adopts a narrative or dialogue that deals with the image of a nurse in a novel as a unit of analysis, The image determining factors of previous studies were integrated and categorized into 4 types and considered. As a result of analyzing the image of a nurse in the novel, First, traditional image types include Lee Kwang-soo 『Love』, Kim Eui-jung 『Doctor Han』, Jo Jung-rae 『Han River』, Gong Ji-young's 「Field of Stars」, Baek Min-seok 「Poor Little Hans」 Second, social image types include Kang Kyung-ae 「Dark」, Kim Kyung-wook 「Heaven's Gate」, Choi Jeong-hee 「Cheonmaek」 Third, professional image types include Lee Cheong-jun 「Mr. Jo Man-deuk」, 「Discharge」, Choi In-hoon 『The Square』, Kim Yeon-soo 「The Night in the Tunnel Where I Listened to Jusaeng Tudipini」, Jeong Se-lang 『Public health teacher Ahn Eun-young』and Fourth, personal image types include Choi In-ho 「Apprentice Patient」, Kim Jeong-han 「The Third Ward」, Eun Hee-kyung 『Minor League』, Hoon Kim 「Hwajang」, Ha Seong-ran 「The Joy of Eating」, Kim Ji-yeon 「Hippocrates Love Song」, Park Kyung-ri 「Era of Distrust」, Jeong Mi-kyung 「The Lady of Arsenal」 typed as. Through the image of the nurse in the novel, the implications of the novel for human care were discussed.