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Body Residue-based Approach as an Alternative of the External Concentration-based Approach for the Ecological Risk Assessment (외부환경농도에 기반한 생태위해성 평가방법의 대안으로서 생체잔류량 접근법)

  • Lee Jong-Hyeon
    • Environmental Analysis Health and Toxicology
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    • v.21 no.2 s.53
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    • pp.185-195
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    • 2006
  • 환경오염물질로부터 수생태계 보호를 위한 표준적인 평가 및 관리 수단인 수질환경기준은 오염물질의 독성작용이 일어나는 표적기관에서의 오염물질의 농도에 대한 대체측정치로서 환경 내 오염물질의 농도를 이용해 왔다. 이러한 '외부환경농도에 기반한 접근방법'은 표적기관에서의 독성물질의 농도가 생물체내 농도에 비례하고, 결국 외부환경농도에도 비례할 것이라고 가정한다. 따라서 환경오염물질의 생물이용도나 생물축적 양상의 차이 때문에 고유 독성치를 비교 평가하는데 한계가 있다. 이와 달리 '생물체내 농도에 기반한 접근방법(이하 생체잔류량 접근법)'은 환경오염물질의 생물이용도나 종 특이적 생물축적 양상과 관련된 불확실성을 제거하고, 환경오염물질 고유의 독성을 비교 평가할 수 있게 해준다. 특히 생체잔류량 접근법을 독성동태학 및 독성역학 모델과 함께 사용하는 경우는 실제 현장에서 일어나는 복잡한 노출조건에서의 독성영향을 예측하는데 활용할 수 있다. '생체잔류량 접근법'은 독성기작별 임계잔류량(Critical Body Residue)을 결정함으로써 생물모니터링의 결과를 해석하는데 적용되고 있다. 또한 생태위해성평가를 위해서 필요한 '무영향예측농도(Predicted No-effect Concentration, PNEC)를 예측하기 위한 방법으로 생체 내 잔류량에 기반해서 농도-시간-반응관계를 기술하고, 예측할 수 있는 새로운 유형의 독성역학 및 독성동태학 모델을 제시하고, 생체내 '무영향농도(No Effect Concentration, NEC)'를 추정하게 해 준다. 특히 생체내 NEC는 '무영향관찰농도(No Observed Effect Concentration, NOEC)'와 '영향농도(Effect Concentration, EC)'처럼 분산분석이나 회귀분석모델과 같은 통계적 모델에 기반해서, 농도-반응관계만을 기술할 뿐인 기존 독성모델을 대체할 대안으로 최근에 OECD와 ISO에 의해서 추천되었다.분석을 시행한 결과 인지기능 장애정도 및 MMSEK 점수 증가에 따른 사망위험도는 어느 모형에서도 인지기능 장애정도가 사망에 미치는 위험도는 통계적으로 유의하지 않았다(표 6, 표 7). 이상 본 연구는 농촌지역 노인들에서 인지기능 장애정도가 사망에 미치는 영향을 알아보고자 하였지만, 인지기능 장애정도가 사망에 미치는 영향을 통계적으로 유의하게 고찰하지 못하였다.의한 차이를 보였다. (P<0.05, P<0.001) 5. Excelco로 부식처리된 도재가 5% HF 용액으로 부식처리된 도재보다 부식정도가 더 현저하였다.은 제언을 하고자 한다. 먼저, 학교급식에 대한 식단 작성 시 학생들이 학교에서 제공되기 원하는 식단에 대한 의견을 받고 그 의견에 대한 결과를 게시하여 학생들이 제공되기 원하는 식단을 급식 시 제공하여 학생들이 식단선택에 동참할 수 있는 기회를 주는 것이 바람직하겠다. 또한 영양사는 학급의 반대표와의 정기적인 모임을 가짐으로서 학생들의 불만사항 및 개선 요구사항에대해 서로 의견을 교환하여 설문지조사가 아닌 직접적인 대화를 하여 문제점을 파악하고자 하는 적극적인 자세가 필요하겠다. 특히 아침식사의 결식 빈도가 높았고 이는 급식성과에 부정적인 영향을 줄 뿐 아니라 학교에서 제공하는 음식의 섭취정도에도 영향을 주고 있으므로 학생들에게 학부모와 전담교사 및 학교영양사는 학생들에게 이상적인 아침식사에 대한 교육은 물론이고 아침식사를 실천할 수 있도록 다양한 방안에 대해 함께 연구해야 하겠다. 정부차원에서 학교급식에 아침식사 프로그램을 도입할 수 있는 방안을 연구하고, 아침을 결식하는 학생이 학교에서 수업시작 하기 전에 간단한 식사를 할 수 있는 정책 도입이 필요하다acid의 생성량(生成量)을 측정(測定)하였는데 periodate의 소비량(消費量)은 1.23 mole, formic acid의 생성량(生成量)은 0.78 mole이다.한 경우도 비교적 많이 먹고 있었다(24.3%). 남 여

Bacterial Distribution and Variation in Water Supply Systems (상수도계통에서의 세균 분포 및 변화)

  • 박성주;조재창;김상종
    • Korean Journal of Microbiology
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    • v.31 no.3
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    • pp.245-254
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    • 1993
  • Distribution and variation of bacterial densities of heterotrophic plate count (HPC) and Enterobacteriaceae in the water supply systems comprising raw, treated, and three tap water samples of a water treatment plant in Seoul were studied 23 times from 1991 to 1992. HPC bacteria of raw. treated, and tap waters on $R_{2}A$ agar media were at a density of $1.22{\times}10^{3} to 3.05{\times}10^{5}$, $1.50{\times}10^{1} to 4.29{\times}10^{3}$ and 2 to $5.41{\times}10^{3}$ cfu/ml, respectively. Densities of Enterobacteriaceae in raw, treated, and tap waters on mENDO-LES agar media ranged from 0.] to 8200 cfu/ml, 0 to 17.5 cfu/JOO mI. and 0 to 47.5 cfu/IOO ml, respectively. Injured Enterobacteriaceae of treated and tap waters on m-T7 agar media were at a density of o to 27 and 0 to 35 cfu/100 mI. These results showed that the density of bacteria in the treated water outflowing from the water plant significantly increased as the water flowed along the distribution sytems, which is so-called bacterial regrowth. The predominant bacteria] types in the water supply system were Pw'udomonas and Acinerobacter. In raw water, the ratio of Pseudomonas was higher than that of Acinetobaeter, but in treated and tap waters. both ratios were reversed. The most predominant species of Enterobacteriaceae was Enterobacter agglomerans. Some species such as Citrobacter freundii. Escherichia coli. Klebsiella pneumoniae. and Shigella dysenteriae which are opportunistic pathogens or pathogens were not found in the treated water but additionally detected in tap waters.

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Antifungal Activity of Bacillus sp. BCNU 2003 against the Human Pathogenic Fungi (인체 병원성 진균에 대한 Bacillus sp. BCNU 2003의 항진균 효과)

  • Choi, Hye-Jung;Yang, Uk-Hee;Kim, Ya-Ell;Choi, Yeon-Hee;Ahn, Cheol-Soo;Jeong, Young-Kee;Kim, Dong-Wan;Joo, Woo-Hong
    • Journal of Life Science
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    • v.20 no.2
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    • pp.269-274
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    • 2010
  • An antifungal antibiotic-producing strain, BCNU 2003, was isolated from forest soil in Korea. The morphological and physiological characters, and 16S rRNA sequences analysis of strain BCNU 2003 identified this strain as Bacillus genus. The Bacillus sp. BCNU 2003 showed strong antifungal activities against Aspergillus niger, Trichophyton mentagrophytes and Trichophyton rubrum with inhibition ranging from 62.05 to 63.49% by using dual culture technique. Bacillus sp. BCNU 2003 produced a maximum level of antifungal substances under aerobic incubation at 28oC and pH 6.5-7.2 for 6 days in LB broth. Ethyl acetate extract of the cultured broth showed strong antifungal activity and a broad antifungal spectrum against various pathogenic fungi. The minimum inhibitory concentration (MIC) values for its active extracts ranged between 0.0625 mg/ml and 1 mg/ml. In addition, Bacillus sp. BCNU 2003 was determined to have the ability to produce enzymes such as amylase, protease, gelatinase and catalase.

The Effect of Using Analogies in High School Earth Science Classes (고등학교 10학년 과학 '지구의 변동' 단원에서 비유물 활용의 효과)

  • Kim, Sang-Dal;Kim, Jong-Hee;Lee, Ji-Eun
    • Journal of the Korean earth science society
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    • v.24 no.5
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    • pp.393-401
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    • 2003
  • The purpose of this study is to research the effect of using analogies in high school earth science classes. According to the usage of TWA model, three types of teaching strategies were developed: text developer-generated, teacher-generated, and student-generated analogies. The model described in this paper began with a task analysis of highschool science textbooks for grade 10 to identify how the textbook authors used analogies to explain plate tectonics concepts. In this study, 210 students were sampled from first graders of high school. After 7 classes, the consciousness of students was investigated with questionnaires. The results are as follows: 1. Many plate-tectonics analogies are used in high school science textbooks (total 25). Teachers and authors construct effective analogies to help students build on their relevant knowledge by applying it to new knowledge acquired from textbooks. 2. Analysis of the data indicate that instruction using student-generated analogies was more effective than others. But in the class in conveying complicated concepts (ex. transform fault), teacher-generated instruction was effective. Teachers need to be aware of the weakness of using analogies in order to select the most appropriate analogies. 3. Making analogies in general, as well as using analogies have systematic steps. Analogies should be used after considering student's preconception, teacher's consciousness and text author's intention to use analogies as powerful instructional tools.

A Case of Squamous Cell Carcinomatous Lung Abscess with Multiple Metastatic Abscesses (다발 전이성 농양을 일으킨 편평상피세포암성 농양 1예)

  • Lim, Ju Eun;Kim, Eun Young;Jang, Ji Eun;Son, Ji-Young;Jung, Ji Ye;Park, Byung Hoon;Lee, Kyung Jong;Yoon, Yeo Wun;Byun, Min Kwang;Lee, Sa Rah;Kang, Young Ae;Moon, Jin Wook;Park, Moo Suk;Kim, Young Sam;Jang, Joon;Park, Young Nyun;Kim, Se Kyu
    • Tuberculosis and Respiratory Diseases
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    • v.66 no.5
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    • pp.390-395
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    • 2009
  • Among the bronchogenic carcinomas, especially squamous cell carcinoma and large cell carcinoma frequently present with cavitation, which may result from tumor necrosis. Cavitary lesions of the tumor are occasionally associated with infection and misdiagnosed as benign lung abscess owing to the partial responsiveness to antibiotics. It is very difficult to distinguish the carcinomatous abscess from the benign lung abscess, because of their similar clinical and radiologic features. Delay in diagnosis of underlying lung cancer may result in poor outcome. Therefore, clinicians should remember that the patients with highly suspicious carcinoma of the lung should undergo further precise examinations to find out malignant cells.

A Survey of Preference for Commercial Makgeolli among Chinese Students in Korea (국내 시판 막걸리에 대한 중국인 유학생의 기호도 조사)

  • Jeon, Ki-Suk;Park, Shin-In
    • Culinary science and hospitality research
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    • v.20 no.4
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    • pp.115-126
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    • 2014
  • The purpose of this study was to offer primary information for development of Makgeolli adapted to the tastes of Chinese and marketing strategies for promoting consumption of Makgeolli in the Chinese market. This study was intended to investigate the Makgeolli drinking behavior through a survey and the sensory properties and preference of fresh and sterilized Makgeolli through sensory evaluation focusing on the Chinese students in Korea, becoming potential consumers of Makgeolli. The survey was conducted from October 9th to October 30th, 2013, and then 117 copies were adopted for the analyses. The results are as follows. 71.8% of the subjects liked Makgeolli, 56.4% drank 5-6 times a week, and 25.7% drank more than 2 bottles at a time. 61.5% of the subjects had purchasing experience. The routes of collecting information about Makgeolli were acquaintances(66.7%) and media sources(28.2%). In the sensory evaluation, sterilized Makgeolli(BS) that has a fresh odor, sweet and sour taste, cooling sensation, and good aftertaste got the best score in the overall acceptability, and fresh Makgeolli(KD) that has a strong nuruk odor, turbidity, bitter taste, and heavy mouthfeel got the lowest score in the overall acceptability. These results show that sweet, fresh, and refreshing Makgeolli suits Chinese's taste and word of mouth marketing through the expansion of tasting events would promote Makgeolli consumption in the Chinese market.

Effects of Bird Ingestion on Seed Dispersal and Germination of the Elaeagnus macrophylla (보리밥나무(Elaeagnus macrophylla)의 종자 산포와 발아율에 미치는 조류의 영향)

  • Choi, Chang-Yong;Chae, Hee-Young
    • Journal of Korean Society of Forest Science
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    • v.96 no.6
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    • pp.633-638
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    • 2007
  • The Elaeagnus macrophylla is a stenoecious evergreen plant with nitrogen-fixing symbionts and its timing of fruit-ripening coincides with spring migration of many birds in southwestern Korea. To recognize bird species which eat fleshy fruits of the Elaeagnus macrophylla and to evaluate the effects of bird ingestion on seed germination and dispersal, we monitored birds and carried out germination experiments using its fruits and seeds from March to April 2007 at Hongdo Island, Jeonnam Province, Korea. As a result, eight species of birds including the Gray Starling (Sturnus cineraceus), the Brown-eared Bulbul (Hypsipetes amaurotis) and the Dusky Thrush (Turdus naumanni) ingested the fruits. Germination rate was enhanced but length of seed dormancy was instead shortened in ingested (collected from the feces of birds) and manually extracted seeds (obtained directly from the fruits) than in intact fruits collected directly from the plant. Moreover, the possible scale of seed dispersal by the frugivorous birds ranged up to 6.9 ha based on home ranges of starlings. Consequently, the Elaeagnus macrophylla supplies food resources for migratory birds, and the birds give the plant opportunities of new colonization. We suggest that this kind of interaction between the nitrogen-fixing plant and avian seed dispersers is applicable as a process of natural restoration in degraded coastal evergreen forests.

An Investigation on the Reasoning Types of Mathematical Problems on the Content of 'Set and Statement' and 'Sequences' (수학 교과에서의 추론 유형의 문제에 관한 탐색 -집합과 명제, 수열 영역을 중심으로-)

  • Hwang, Hye Jeang;Kim, Seul Bi
    • Communications of Mathematical Education
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    • v.28 no.4
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    • pp.529-552
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    • 2014
  • Recently, mathematical reasoning has been considered as one of the most important mathematical thinking abilities to be established in school mathematics. This study is to investigate the mathematical problems on the content of 'Set and Statement' and 'Sequences' in high school according to the four types of reasoning, namely Making Conjectures, Investigating Conjectures, Developing Arguments, and Evaluating Arguments. Those types of reasoning were reconstructed based on Johnson's six types of reasoning suggested in 2010. The content is dealt with in 'Mathematics II' textbook developed and published according to the mathematics curriculum revised in 2009. The subject of this study is nine types of textbooks and mathematical problems in the textbook are consisted of as two parts of 'general problem' and 'evaluation problem'. Finally, the results of this study can be summarized as follow: First, it is stated that students be establishing a logical justification activity, the highest reasoning activity through dealing with the 'Developing Arguments' type of problems affluently in both 'Set and Statement' and 'Sequence' chapters of Mathematics II textbook. Second, it is mentioned that students have an chance to investigate conjectures and develop logical arguments in 'Set and Statement' chapter of Mathematics II textbook. In particular, whereas they have an chance to investigate conjectures and also develop arguments in 'Statement', the 'Set' chapter is given only an opportunity of developing arguments. Third, students are offered on an opportunity of reasoning that can make conjectures and develop logical arguments in 'Sequences' chapter of Mathematics II textbook. Fourth, Mathematics II textbook are geared to do activities that could evaluate arguments while dealing with the problems relevant to 'mathematical process' included in 'general problem'.

II. Kernel Characters of Korean Indigenous Corn Lines (Zea maize L.) in Respect of Geographical and Cultural Magnitude (지역별 재배규모별로 본 재래종 옥수수의 특성조사(II))

  • Bong-Ho Choe;In-Sup Lee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.23 no.2
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    • pp.133-140
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    • 1978
  • Kernel softness. density. size and 100 kernel weight of Korean local corn lines (Zea mays, 1.) were studied to find any relationship with cultural magnitude in regions. Kernel density. softness and size were greater in the Kangwon area than in other less growing areas. Kernel size was the only character showing great relationship with growing magnitude. Most of the collected lines were flinty type and no differences were found among various growing magnitudes. Kernel density was also the same through the growing magnitudes.

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Ecological Diagnosis on Korean Red Pine (Pinus densiflora Seibold & Zucc) Stands in Isolated Urban Forest (도시(都市) 내(內) 고립(孤立) 림지(林地)의 소나무림(林)에 대(對)한 생태학적(生態學的) 진단(診斷))

  • Cho, Hyun-Je
    • Journal of Korean Society of Forest Science
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    • v.96 no.4
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    • pp.419-424
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    • 2007
  • The urban forest offer many opportunities to maintain and enhance local and regional biological diversity. Pinus densiflora stands in isolated urban forest in five areas of Seoul, Incheon, Daegu, Ulsan, and Cheongju were investigated by landscape and community ecological methods for diagnosis of current status and construction of conservation plan. Species composition of five study areas revealed regional characteristics. As the result of stand dynamics, absence of pine seedlings and saplings were observed. Cheongju, significantly, revealed highest species diversity (H'=1.86) and richness (24) among study areas, and the opposite was true for Daegu (1.35 for H', and 14 for richness). Ratio of alien species was highest in Daegu (15.8%) (F=5.05, p=0.0016). Based on landscape analysis, complexity of pine patch was higher in local city than metropolitans, but statistically not significant (p=0.133). Complexity of pine patch revealed significant positive correlation with diversity and richness, but not with percentage of aliens. Synthetically, ecological management based on community and landscape ecological information was recommended. Cautious artificial regeneration strategy was necessary to regenerate pine forest in urban area.