• Title/Summary/Keyword: 기억효과

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Study on the Characteristics and Quality Level of Single Subject Researches in the Stroke Patients : The Field of health care ~ (뇌졸중 환자를 대상으로 한 단일대상연구의 특성과 질적 수준에 관한 연구: 보건의료 분야를 대상으로)

  • Sim, Kyoung-Bo
    • The Journal of Korean society of community based occupational therapy
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    • v.8 no.2
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    • pp.15-28
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    • 2018
  • Objective : This study sought to characterize and determine the qualitative level of a single target study for stroke patients. Methods : The National Science and Technology Information Center (NDSL), DBpia (DBpia), RISS (Radical Research Information Service), Korea Research Information (KISS), and the National Assembly Library's original case study from 2002 to 2017. A total of 24 single target research papers were selected through the screening process to analyze the quality level of research methods and research design. Results : ABA design was th most common study design method. One person was the most with 12(50%). and three were the second with 8(33.3%). Imagination was the most used as an independent lawyer. Dependent variables had the highest level of situability and one-sidedness. The study was also conducted with a variety of target behaviors, including 'memory', 'visual attention', 'dysphagia', 'visual-motor coordination', 'balance', 'activity of daily life' and 'edema' behaviors. It also showed a positive effect on all dependent variables. The Qualitative level was found to be above the intermediate level except for one study. Conclusion : It is academic significance that this study analyzes the items to be prepared for in the performance of a single target study and further studies may require the establishment of a weak but good-quality single target study for researchers conducting research in local communities and clinical sites.

Antioxidant and growth inhibitory activities of Mesembryanthemum crystallinum L. in HCT116 human colon cancer cells (아이스플랜트의 항산화 및 HCT116 인체 유래 대장암세포 성장억제 활성)

  • Seo, Jin A;Ju, Jihyeung
    • Journal of Nutrition and Health
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    • v.52 no.2
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    • pp.157-167
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    • 2019
  • Purpose: This study examined the antioxidant and cancer cell growth inhibitory activities of an ethanol extract and different solvent fractions of Mesembryanthemum crystallinum L. (ice plant). Methods: The ice plant was freeze-dried, extracted with 99.9% ethanol, and then fractionated with hexane, ethyl acetate, butanol, and water. The total polyphenol content (TPC), total carotenoid content (TCC), 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity (RSA), and ferric reducing antioxidant power (FRAP) were measured. Assays using 2',7'-dichlorofluorescin-diacetate and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide were performed to measure the intracellular reactive oxygen species (ROS) and cell growth, respectively. Annexin V/propidium iodide staining and cell cycle analysis were performed for the detection of apoptosis and cell cycle arrest. Results: TPC, TCC, RSA, and FRAP of the ethanol extract (EE) were 3.7 mg gallic acid equivalent/g, $13.2{\mu}g/g$, 21.0% (at a concentration of 5 mg/mL), and 21.0% (at a concentration of 5 mg/mL), respectively. Among the different solvent fractions, the butanol fraction (BF) showed the highest TPC (5.4 mg gallic acid equivalent/g), TCC ($86.6{\mu}g/g$), RSA (34.9% at 5 mg/mL), and FRAP (80.8% at 5 mg/mL). Treatment of HCT116 human colon cancer cells with EE and BF at concentrations of 250 and $500{\mu}g/mL$ reduced the levels of intracellular ROS. Concomitantly, EE and BF resulted in the dose-dependent inhibition of cell growth (at the concentrations of 125, 250, and $500{\mu}g/mL$ for 24 ~ 48 h) and the induction of apoptosis (at the concentrations of 250 and $500{\mu}g/mL$ for 48 h) in HCT116 cells. An increased G2/M cell population was also found in the BF-treated cells. Conclusion: These results suggest that ice plant possesses antioxidant and growth inhibitory activities in colon cancer cells.

A Study on Visual Attention Factors for Advertising Photographs (광고 사진을 위한 시각적 주의 기초요인 연구)

  • Kim, Dae-Wook
    • Journal of Digital Convergence
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    • v.17 no.3
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    • pp.413-425
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    • 2019
  • We see many images every day, some of these images are stored in memory, and the majority are immersed in the unconscious world. Visual elements are seen by personal attention or by visual or biological attention factors. Specific and clear discovery of this visual attention has not yet been made. However, there is an interesting discussion of this visual attention in the fields of interior, design, visual perception, advertising, and psychology. Advertising photographers are expected to produce what their work will have on viewers and consumers. However, the adjustment of subject, exposure, color, or post-production, which could have a visual effect on the consumer, was determined only by the photographer's senses rather than the experimental verification. The advertisement photographs provide a specific image related to the object to be advertised and deliver a certain message. Therefore, it is necessary to understand the effect of the image in a certain visual way. According to previous studies, there are two major factors that affect the visual impression of the viewer. One is the factor depending on the type and content of the subject and the other is the factor about the density and color of the subject. The purpose of this study is to investigate the meaningful changes in the visual perception depending on the shape, content, color and tone of the subject, which can be called the main subject, And to analyze the effects of I will study some implications of visual elements through various analyzes.

A Study on Description about Archival Materials in Film Archives (영화 기록의 기술에 관한 연구)

  • Kim, Jin Sung
    • The Korean Journal of Archival Studies
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    • no.30
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    • pp.89-123
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    • 2011
  • Archival materials in film archives is a memories and archival documents of human which is generated from cultural activities of human being, and provided long-term relevant information. However, it is different general public audio-visual records because main purpose of representing culture to create the contents of private sector rather than evidence of the factual information of public service activities. Therefore, should determine the description principle and rule in order to reflect specific physical, intellectual characteristics. So as to control the description, that is need in the textual standards to base the specific purposes and rules thus analyzed the international description standards as Dublin Core, ISAD(G), FIAF Cataloguing Rules For Film Archives. As a result, more effectively to describe archival materials in film archives required significant modifications in the organizations of the areas and the elements. This study argues that first, to divide existence the concept and the reality (work/item) of archival materials in film archives. Second, to need understanding and indicating their content, context, structure. Third, to establish of the areas and the elements including a characteristic of it. The final suggestion organizes separately to 6th and 8th areas, 22th and 25th elements in two parts. This conclusion does not prepare to refer the status and/or policy of a particular film arhicve, can be set accordingly to a specific elements or sub-elements by the film archives.

Gossypii Semen oil alleviates memory dysfunction in scopolamine-treated mice (면화자 정유의 기억력 손상 완화 효과)

  • Lee, Jihye;Jung, Eun Mi;Lee, Eunhong;Jang, Gwi Yeong;Seo, Kyung Hye;Kim, Mi Ryeo;Jung, Ji Wook
    • The Korea Journal of Herbology
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    • v.36 no.2
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    • pp.1-9
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    • 2021
  • Objectives : Gossypium arboreum (cotton) is traditionally used to treat various health disorders. However, anti-amnesic effect of G. arboreum has not been reported. The objective of this study was to investigate in-vivo the anti-amnesic effects along with in vitro antioxidant and acetylcholinesterase (AChE) inhibition potential in G. arboreum seed essential oil. Methods : The essential oil of G. arboreum obtained by solid phase microextraction (SPME) techniques were identified by gas chromatography-mass spectroscopy (GC-MS). 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay were performed to determine the antioxidant activity at various concentrations (312.5, 625, 1250, 2500, 5000, 10000 ㎍/㎖. Y-maze, passive avoidance and Morris water maze tests were carried out to evaluate improved effect on scopolamine (1 mg/kg)-induced memory dysfunction at the dose level of 50, 100 and 200 mg/kg. Donepezil (5 mg/kg) was used as a positive drug control. We performed acetylcholinesterase (AChE) activity assay in ex vivo. Results : Five volatile compounds were identified in G. arboreum. The assays of DPPH and ABTS revealed that G. arboreum increased antioxidant activity in a dose-dependent manner. G. arboreum ameliorated the percent of spontaneous alternation in the Y-maze test, shortened step-through latency in the passive avoidance test, and increased swimming time in the target zone in the Morris water maze test. In addition, G. arboreum inhibited the AChE activity. Conclusions : Based on these findings, G. arboreum may aid in the prevention and treatment of learning and memory-deficit disorders through antioxidant and AChE inhibitory activities.

Effect of Fermented Garlic Extract Containing Nitric Oxide Metabolites on Impairments of Memory and of Neural Plasticity in Rat Model of Vascular Dementia (산화질소 대사체 함유 마늘 발효 추출물 이용 혈관성 치매 흰쥐 모델의 기억력 및 신경가소성 장애 개선 효과)

  • Zhang, Xiaorong;Moon, Se Jin;Kim, Yoo Ji;Jeong, Sun Oh;Kim, Min Sun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.36 no.2
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    • pp.59-65
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    • 2022
  • Rodent model for chronic cerebral hypoperfusion caused by bilateral carotid artery occlusion (BCAO) show clinically relevant evidences for vascular dementia and impairments of synaptic plasticity in the hippocampus. The purpose of this study was to evaluate effect of fermented garlic (F-Garlic) extract with NO metabolites on cognitive behaviors, synaptic plasticity, and molecular events in the hippocampus following BCAO. Adult male Sprague-Dawley rats were randomly divided three experimental groups into: control+water; BCAO+water; BCAO+F-Garlic. Animals were treated with oral administration of F-Garlic in tap water as a drinking water after surgery for 4 weeks. On passive avoidance test and Y-maze test, BCAO+water showed a significant decrease in step-through latency and spontaneous alteration, indicating deficit of hippocampal memory formation but the treatment of F-Garlic significantly increased these cognitive behaviors. In control+water, a robust increase in the amplitude of evoked field excitatory postsynaptic potentials was observed by theta burst stimulation to hippocampal neural circuit indicating formation of long-term potentiation (LTP) in the hippocampal CA1. BCAO+water showed a highly significant deficit in LTP induction 4 weeks after BCAO. On other hand, daily oral administration of F-Garlic extract caused the marked preservation of LTP induction. Moreover, parvalbumin was markedly reduced in the CA1, especially, in the stratum radiatum of BCAO+water. In contrast, BCAO+F-Garlic mitigate a significantly reduction of the parvalbumin. In summary, these results suggest that daily oral administration of F-Garlic extract can ameliorate cognitive memory deficit through the preservation of synaptic plasticity and interneurons integrity in the hippocampus in rodent model of chronic cerebral hypoperfusion.

Design of Over-sampled Channelized DRFM Structure in order to Remove Interference and Prevent Spurious Signal (간섭 제거 및 스퓨리어스 방지를 위한 오버샘플링 된 채널화 DRFM 구조 설계)

  • Kim, Yo-Han;Hong, Sang-Guen;Seo, Seung-Hun;Jo, Jung-Hun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.8
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    • pp.1213-1221
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    • 2022
  • In Electronic Warfare, the need to develop a jamming system that protects our location information from enemy radar is constantly increasing. The jamming system normally uses wide-band DRFM(Digital Radio Frequency Memory) that processes the entire bandwidth at once. However, it is difficult to jam if there is a CW(Continuous Wave) interference signal in the band. Recently, instead of wide-band signal processing, a structure using a filter bank that divides the entire band into several sub-bands and processes each sub-band independently has been proposed. Although it is possible to handle interference signal through the filter bank structure, spurious signal occurs when the signal is received at a boundary frequency between sub-bands. Spurious signal makes a output power of jamming signal distributed, resulting in lower JSR(Jamming to Signal Ratio) and less jamming effect. This paper proposes an over-sampled channelized DRFM structure that enables interference response and prevents spurious signal for sub-band boundary frequency input.

Perilla Frutescens Extract Protects against Scopolamine-Induced Memory Deficits in Mice (스코폴라민으로 유도한 기억력 손상 모델에서 소엽 추출물의 보호 효과)

  • Lee, Jihye;Lee, Eunhong;Jung, Eun Mi;Kim, Dong Hyun;Kim, Sung-kyu;Park, Mi Hee;Jung, Ji Wook
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.35 no.3
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    • pp.97-103
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    • 2021
  • Perilla frutescens (P. frutescens) is an important herb used for many purposes such as medicinal, aromatic, and functional food in Asian countries and has beneficial effects such as antioxidant activity, anti-inflammation activity, anti-depression activity, and anxiolytic activity. However, there have been no studies on the protective effect of P. frutescens extract (PFE) on amnesia in vivo. The present study aimed to investigate whether PFE protects memory deficit using a scopolamine-induced mice model and elucidate the underlying mechanisms involved. The protective effect of PFE against scopolamine-induced memory deficits was investigated using Y-maze, passive avoidance, and Morris water maze tests. Furthermore, the potential mechanisms of PFE in improving memory capabilities related to the cholinergic system and antioxidant activity were examined. PFE significantly increased spontaneous alternation in the Y-maze test, step-through latency in the passive avoidance test, and swimming time in the target quadrant in the probe test when compared to the scopolamine-treated group. Likewise, PFE significantly decreased escapes latency in the Morris water maze test. PFE could not regulate cholinergic function in acetylcholine level and acetylcholine esterase activity. However, PFE increased DPPH radical scavenging activity dose-dependently and total polyphenol content was 127.7±1.2 ㎍ GAE/mg. The results showed that the PFE could be a preventive and/or therapeutic candidate for memory and cognitive dysfunction in Alzheimer's disease.

Entertainers' Conceptual Perception and Behavioral Pattern on their "Positive Influence" ('선한 영향력'에 관한 엔터테이너들의 개념 인식과 발현 양태)

  • Kim, Jeong-Seob
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.4
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    • pp.199-209
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    • 2020
  • "Positive Influence(PI)" of popular star has recently emerged as a social concern, but the lack of prior research has led to confusion over its concept and range of activity. On this point, this study carried out to lay the groundwork for discussions on the systematization of related theories, focused on identifying the current situations by analyzing articles for 15 months from January 2019 to March 2020 when related reports were in full swing. As a result of the analysis of the remarks from the entertainers mentioned in the articles, they were not clearly aware of the concept while doing good deeds under the name of PI in light of the study outcome by Aegean and Singer(2013). The motivations for good deed were classified into six types, including difficulty empathy, fandom reward, participation urge, nidana emphasis, experience subjugation, and memory evocation in the order of frequency of cases. Specific behaviors of PI were followed by donations of money and valuables for 54.4 percent, participation of social agendas for 14.0 percent, volunteering for 13.2 percent, joining campaign for 11.4 percent, other good deeds for 4.0 percent, and philanthropy for 3.0 percent. In occupational analysis, the concentration of donations was also evident. Their activities in the fields of human rights sensitivity, environmental protection and self-management, which are expected to have great effects with their influence, have been extremely poor. The results of the study first require academia to establish a interdisciplinary concept for PI. It also suggests that entertainers and their agencies should take far more strategic approach to evolve the PI event in a way that utilizes the advantages of each job group, such as actors, singers and comedians, and expands the diversity of areas.

An Exploration of the Possibilities for Archival Art as Local Community Archive: Gyeonggi Archive Exhibition and Seongbuk Documenta Exhibition (지역공동체 아카이브로서 아카이브 예술의 가능성 탐색 연구 - 경기아카이브 전시와 성북도큐멘타 전시 사례를 중심으로 -)

  • SEO, U-Seok;KIM, Min Jae
    • Korean Association of Arts Management
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    • no.60
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    • pp.5-35
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    • 2021
  • Profound changes have occurred in the archival landscape since the advent of community archives and the global spread of archival art. This trend can be seen in Korea where a noticeable growth in archival arts and local community archives can be observed. This study explores how archival arts in Korea function when they are specifically intended to play a role in local community archiving. For this purpose, we analyzed the 'Gyeonggi archive_Now (2018)' and 'Seongbuk Documenta (2016-2018)' exhibitions, which were both exemplary cases of archival arts exhibited in connection with local community archives. Based on the analysis of the Gyeonggi Archive, which was aimed at strengthening the local identity of Gyeonggi Province, as well as the analysis of Seongbuk Documenta, which focused on the loss of place that resulted from redevelopment projects in the area of Seongbuk-gu, this study identifies the multiple roles of artists in archiving work. This study also reveals the variety of archiving works that exist and illuminates the value that such initiatives have in constructing local identity and reviving a sense of place. In particular, this research shows that archival art has the potential to empower local community archives while also providing opportunities to boost artistic creation. Our research concludes by highlighting the necessity of promoting the right environment and conditions that are required for archival arts if they are to play a role not only in keeping records and memories but also in producing further knowledge and discourse in a local community.