• Tuberculosis and Respiratory Diseases
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• v.47 no.2
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• pp.265-271
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• 1999

Patients with mediastinal teratoma are usually asymptomatic, but may develop symptoms by rupture into adjacent structures which result in pneumonia, hemoptysis, pleural effusion, pericardial effusion, or pneumothorax. Rarely, life-threatening acute respiratory distress require a emergency surgery. Rupture into pleural cavity may result in pleuritis and pleural effusion with severe anterior chest or back pain. The symptom must be differentiated from other common intrathoracic distress diseases. Clinical, cytologic and radiologic examinations of pleural effusion, and moreover, measurement of enzymes such as amylase or insulin, which is secreted from pancreatic tissues, in pleural effusion and cystic fluid enabled us to make the diagnosis of rupture of mediastinal teratoma preoperatively.

• 농업기술회보
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• v.50 no.2
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• pp.39-39
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• 2013

수수는 폴리페놀, 플라보노이드 등 다양한 기능성 성분이 많이 함유하고 있어 몸속 활성산소를 막는 항산화 효과와 더불어 고지혈증 예방, 항비만 및 항당뇨 등 주요 생활습관병에 우수한 건강기능성 식품으로 주목받고 있다. 하지만 재래종자는 유전적으로 순도가 높지 못해 쓰러짐에 약하고 수량이 낮아 품종개선이 필요했다. 이에 따라 농촌진흥청에서는 쓰러짐에 강하고 수량이 많은 메수수 '동안메'를 2012년에 육성하였다.

• Journal of Wetlands Research
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• v.10 no.3
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• pp.133-139
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• 2008

Urban streams are degrading functional role due to development and pollution. This study chose the representative stream of Do-rim and identified flora and fauna. The ecological survey aimed at identifying indicator of urban streams for measuring urban healthiness and we discussed the possibility of wetland conservation area. From the beginning of Dorim stream to An-yang mixture we were successfully identified 113 species of plants, 9 of mammals, 23 of birds, 4 of amphibians, 2 of reptiles and 2 of fish species. Terrestrial insects were 71 species. The wetland vegetation is quite various and we suggested 4 different vegetation zones (aquatic vegetation zone, emergent zone, riparian-meadow zone, riparian-woodland zone) depending on distance from the flowing water stream and vegetation characteristics for urban stream management.

• Journal of Sensor Science and Technology
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• v.11 no.3
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• pp.125-131
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• 2002

Respiratory air flow rate is necessarily measured for the pulmonary function evaluation. The currently used devices are exposed to the problems of measurement reliability and cross-patient infection. The present study introduced a new technique which converted the bidirectional air flow rate into averaged dynamic pressure based on the famous Bernoulli's energy conservation principle. Single use plastic sensing element was assembled within the flow tube(mouth piece) made of paper, which was named "functional single use flow tube". Experiment demonstrated only ${\pm}1.5%$ relative error in the standard 3L volume measurement procedure well within the error limit suggested by the American Thoracic Society(ATS). Disposable use design completely eliminated cross-patient infection. The present device is best useful and safe for clinical respiratory air flow measurement such as spirometry.

• Journal of Food Hygiene and Safety
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• v.22 no.1
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• pp.15-22
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• 2007

Health functional foods refer to food which manufactured in the form of a tablet, capsule, granule or pill, using materials and ingredients with useful function for a human body in Korea. It needs to be confirmed as safe. Microbiological analyses on 37 samples of botanical raw materials used in the health functional food were performed. Microbiological analyses and probability of irradiation using PSL on 4 samples of aloe powder products were studied. In health functional food ingredients APC was $10^{3}-10^{6}\;CFU/g$ and coliform counts were $10^{2}-10^{5}\;CFU/g$. Among 37 samples B. cereus were found in 12 samples. Four samples of aloe powder products were tested for possible irradiation using preliminary PSL, Two samples of aloe powder products showed positive on preliminary PSL test for irradiation.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2001.11a
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• pp.44-44
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• 2001

최근들어 환경보호, 자원절약 및 산업의 경제성 확립을 위하여 전세계적으로 자원의 재활 용에 대한 일반 대중의 관심이 고조되고 있으며, 이와 때를 같이하여 각종 재활용 촉진을 위한 법규와 제도가 강화되어가고 있다. 이러한 분위기는 제지산업 분야의 경우 재생펄프 의 사용량 증가로 나타나고 있다. 그 동안 고지를 주된 원료로 사용하던 신문지, 판지 및 라이너지 등의 지종은 고지 사용 비율을 점차 높혀가고 있으며 천연펄프를 주된 원료로 이용하던 고급 인쇄용지와 화장지 분야에도 재생펄프의 사용이 시도되거나 확대되고 있 다. 아울러 전 지종에 걸쳐서 고수율 펄프의 활용 증대를 통한 산림자원 보호 및 경제성 확립에도 많은 노력이 경주되고 있다. 이러한 고지 및 고수율 펄프의 이용 증가 추세는 단 순한 경제적 이유에서 뿐만이 아니라 갈수록 강화되고 있는 환경보전과 자원절감을 달성 하기 위해서 지속되리라고 판단된다. 재생펄프의 이용과 함께 날로 엄격해지는 폐수 배출 규제와 관련하여 제지 공정을 폐쇄 화 방안이 적극 검토되고 있거나 실제로 적용되고 있다. 이에 따라 초지계의 백수 조건이 악화되고 있으며 앞으로 이러한 추세는 심화될 것이 자명하다. 이러한 백수계의 오염은 각종 첨가제의 기능 저하를 유발시키므로 공정 폐쇄화에 대처할 수 있는 새로운 기능성 보류시스템의 개발이 선행되지 않는다면 보류되지 못한 첨가제 혹은 미세분이 초지계를 오염시키는 악순환이 거듭될 것이 자명하다. 따라서 고지 재활용 및 공정 폐쇄화에 적극적으로 대처하기 위해서는 변화되는 원료 및 용수 조건에 능동적으로 대처할 수 있는 새로운 기능성 보류시스템으로서 전분과 마이크 로파티클로 구성된 보류 시스템을 검토하였다. 특히 마이크로파티클 시스템의 구성요소의 하나인 양성전분의 개질에 따른 효과를 평가하기 위해서 다양한 종류의 양성전분을 준비 하고 그 사용에 따른 미세분 보류도, reversibility 등을 측정하였다. 특히 reversibility를 측정함으로써 제지공정상에서의 전단력에 의한 응집에 파괴이후의 재응집 능력을 평가하 였다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.8
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• pp.1105-1113
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• 2015

Bokbunja (Rubus coreanus) is a Korean fruit and wild black raspberry that has antioxidant, anticancer, and beauty effects due to its abundant polyphenols and anthocyanins. The purpose of this study was to investigate the blood flow improvement effect of Bokbunja seed oil (BSO) in a high-fat diet-fed mouse model. We examined improvement of blood flow and its related biomarkers in vivo. Mice were divided into four groups; Control, high fat diet control (negative control, HFD), salmon oil control (positive control, HFD+commercial n-3 fatty acid), and BSO experiment groups (HFD+2 g/2,000 kcal, HFD+4 g/2,000 kcal). After the mice were sacrificed, plasma triglyceride, cholesterol, and blood flow-related biomarkers (coagulation factor 7, 12, serotonin, TXB2, PT, and aPTT) were measured in mouse blood and organs. BSO reduced blood viscosity through improvement of blood lipids (cholesterol and plasma triglycerides) as well as levels of blood coagulation factors and blood platelet activity. BSO also delayed blood coagulation time. Thus, we confirmed that BSO inhibits excessive blood clotting of blood vessels and improves blood flow. Taken together, these results suggest that BSO decreases plasma triglycerides and cholesterol and improves blood flow by regulating biomarkers.

• Journal of Chest Surgery
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• v.41 no.6
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• pp.703-709
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• 2008

Background: Diagnosis and treatment are often successful in the setting of cardiac myxomas. However, cardiac myxomas can lead to catastrophic complications, due to intracardiac obstruction and embolism preoperatively, and can recur postoperatively. Material and Method: We retrospectively reviewed the clinical characteristics, surgical treatment, and recurrence data of 85 patients who underwent cardiac myxoma surgery at Asan Medical Center between November 1994 and June 2007. We analyzed the morphologic characteristics of 58 patients with left atrial myxomas and determined the development of functional mitral valve stenosis and systemic embolism through reviewing the results of preoperative echo-cardiograms to find potential preoperative risk factors. Result: Twenty-seven (31.8%) patients were men, and 58 (68.2%) were women. The mean patient age was $54.5{\pm}14.3$ years. Preoperative symptoms included obstructive symptoms in 41 (48.2%) patients, signs of embolism in 19 (22.4%), constitutional symptoms in 8 (9.4%), and no symptoms in 19 (20.0%). Among the 58 patients with left atrial myxomas, the mean maximal tumor diameter was $4.3{\pm}1.8$ (range $1.1{\sim}8\;cm$)cm. Twenty-six (44.8%) patients had a prolapsing type, defined as a tumor mobile enough to move down. to the mitral. annular plane during diastole, and 32 (55.2%) had villous type, defined as a tumor consisting of multiple fine villous extensions on the surface. Twelve (20.7%) patients had severe functional mitral valve stenosis, and 15 (25.9%) had systemic embolism preoperatively. The incidence of severe functional mitral valve stenosis was significantly higher in patients with the prolapsing type than in those with the non-prolapsing type (p=0.001). The mean maximal tumor diameter in patients with severe functional mitral valve stenosis was $5.1{\pm}1.0\;cm$, significantly larger than that seen in patients without severe functional mitral valve stenosis (p=0.041). The incidence of systemic embolism was significantly higher in patients with the villous type than in those with the smooth type (p=0.006). Postoperative complications were noted in 6 (7.1%) patients, and early mortality was noted in 1 (1.2%). The mean postoperative follow-up duration was $36.2{\pm}37.5$ months, with recurrence reported in 2(2.4%) patients during the follow-up period. The disease free interval were 48, 12 months, respectively. Conclusion: Surgical treatment for cardiac myxomas was performed safely, and long-term prognosis was good. In patients with left atrial myxoma, close attention should be maintained and surgery should be performed promptly in those of prolapsing type, those with large maximal diameter in order to prevent severe functional mitral valve stenosis, and those of villous type in order to prevent systemic embolism. Echocardiography should be followed serially in order to detect recurrence.

• Korean Journal of Food Science and Technology
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• v.39 no.5
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• pp.580-583
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• 2007

Little is known about the genetic variability in lutein content for soybeans (Glycine max L.) cultivated in Korea. Therefore, the objective of this study was to screen high quality soybean cultivars for lutein content. The lutein contents of 23 recommended varieties, 56 sauce varieties, 44 sprout varieties, and 40 local varieties were determined by saponification followed by reversed phase high performance liquid chromatography (HPLC). We found that IT No. 153398 and 22789, originating from sauce and local varieties, respectively, contained significantly higher amounts of lutein as compared to the other 161 samples. Moreover, relevant quantitative differences were found among the samples, which had lutein contents ranging from 83 to $402{\mu}g/100g$ in the recommended varieties, from 39 to $778{\mu}g/100g$ in the sauce varieties, from 52 to $589{\mu}g/100g$ in the sprout varieties, and from 106 to $861{\mu}g/100 g$ in the local varieties, respectively. In summary, this study provides reliable lutein data for soybean cultivars that can be used for breeding studies and the development of functional foods.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.04a
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• pp.65-65
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• 2018

복분자(Rubus coreanus Miquel)는 anthocyanin, phenolic acid, tannin, flavonoid, stilbenoid와 같은 생리활성물질이 풍부하게 존재하는 것으로 보고되었으며 항염증, 항암활성, 항산화효과 등 다양한 생리활성에 대한 효능이 있어 건강식품으로써 애용되고 있을 뿐만 아니라 약용성 건강보조식품 등으로 각광받고 있다. 생물전환(Bioconversion)은 미생물 또는 효소의 생물학적 촉매 기반 천연소재의 생리활성 물질기능성, 생체이용률, 안전성을 증대시키기 위한 방안으로 많은 연구가 진행되고 있으며 아울러 식품, 의약품, 화장품 등 다양한 분야에서 활성화 되고 있다. 본 연구는 불가사리 발효액으로부터 유산균을 분리하였으며, 유전학적 특성을 확인하기 위하여 16S rDNA 염기서열을 분석하였다. 전북 고창에서 수확된 복분자를 분말상태로 유산균과 발효공정을 수행하였으며, 복분자의 최적 추출조건 선정과 발효공정 전 후의 활성을 관찰하였다. 발효공정 후 추출물의 기능성 평가를 진행하기 위하여 DPPH radical scavenging activity, total polyphenol 함량을 확인하여 항산화 효능 및 유효성분 함량을 평가하였다. 또한 대식세포인 Raw 264.7을 사용하여 MTT assay, Nitric oxide (NO) 생성 억제 효능을 확인하여 세포독성 및 항염증 활성을 평가하였다. 실험결과, 발효기간이 다른 불가사리 비료발효액으로부터 16 종의 다양한 균주를 확보하였으며, 생물전환 공정에 유용 균주를 선정하기 위하여 복분자 분말의 발효공정을 실시한 결과 3 종의 유산균 처리군에서 무처리군 대비 DPPH radical 소거능 및 polyphenol 함량이 증가됨을 확인하였다. 그 중 가장 우수한 활성을 나타내는 균주를 16S rDNA 염기서열 분석한 결과 Lactobacillus coryniformis A6-4로 확인되었으며, 발효공정 후 항산화 활성은 무처리군 대비 약 115%, polyphenol의 함량은 무처리군 대비 약 121%로 증가됨을 확인되었다. 또한 발효공정 후 독성활성이 감소되는 경향을 확인되었으며, 항염증 활성이 유의적으로 증가됨을 확인하였다.