• Journal of Life Science
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• v.24 no.9
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• pp.1019-1024
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• 2014

Skeletal muscle atrophy can be defined as a decrease in or a disease of the muscle tissue, or as a disorder of the nerves that control the muscle, through injury or lack of use. This condition is associated with reactive oxygen species (ROS), resulting in various muscular disorders. Exposure to ROS induces muscle atrophy through several biological factors, such as SOD1 and HSP70. We found that cymbidium root extract reduced the $H_2O_2$-induced viability loss in C2C12 myoblasts and inhibited apoptosis. In addition, we showed that the cymbidium root extract increased the expression of HSP70 and decreased the expression of SOD1 in the $H_2O_2$-induced C2C12 myoblasts. These results suggest that cymbidium root extract might have therapeutic value in reducing ROS-induced muscle atrophy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.934-939
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• 2014

The purpose of this study unit a Quadrupedal position of limbs due to changes in the thickness of the trunk muscles to find out, by comparing the difference in muscle activity fours spinal stabilization devices do you need to choose an effective stance is to provide the data. The subjects C # 29 University students healthy adults were recruited. The Rectus abdominis muscle and the transversus abdominis and internal oblique abdominal muscle, external oblique abdominal muscle should be measured. The results of this study Lt. IO, EO, TrA, Rt. TrA, Muscle showed significant differences among the positions. The study reveals that the exercises in Quadrupedal position can activate trunk muscles and the degrees of muscle activities can vary according to the angle.

• Journal of Oral Medicine and Pain
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• v.33 no.4
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• pp.339-352
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• 2008

Aims: The aims of this study were to identify the association between cervical muscle pain and TMD by pressure pain response, and to find cervical muscles showing moderate to severe pressure pain that are correlated with masticatory muscle pain. Methods: Patients(n=129, female 65.9%, mean age 28.8 years) answered a TMD questionnaire asking about headache, neck pain, emotional stress, sleep disturbance, parafunction habits, and pain intensity. A clinical examination of the masticatory system was performed. Of the neck muscles, (1) the upper sternocleidomastoid, (2) the middle sternocleidomastoid, (3) the upper trapezius, (4) the splenius capitis, (5) the semispinalis capitis, (6) the scalene medius, and (7) the levator scapulae muscles were examined by palpation. Pressure pain or tenderness of all palpation sites was scored from 0 to 3 according to the pain response. The variables of sum of pressure pain scores were calculated from pressure pain scores and were used for statistical analyses. Results: Eighty patients(62.0%) answered that they suffer from neck pain in the TMD questionnaire. More than 40% of sternocleidomastoid and upper trapezius examination sites showed moderate to severe tenderness in the cervical muscles, and 36% of middle masseter in the masticatory muscles. For the 129 patients, the sum of cervical muscle pain scores(mean=12.88, SD=8.06) and the sum of TMD pain scores(mean=5.36, SD=5.10) were moderately correlated($\rho$ = 0.502, P < 0.001). The sum of TMD pain scores tends to increase as the sum of cervical muscle pain scores increases(Y = 0.395${\cdot}$X, $R^2$ = 0.659, P < 0.001). In the patients with masticatory muscle disorders, the sum of sternocleidomastoid and upper trapezius pain scores(mean = 8.67, SD = 4.95) and the sum of temporalis and masseter pain scores(mean = 3.37, SD = 3.56) showed moderate correlation($\rho$ = 0.375, P < 0.001). Those two variables were in a proportionate relationship(Y = 0.359${\cdot}$X, $R^2$ = 0.538, P < 0.001). In a partial correlation analysis of the sum of unilateral pain scores, the sum of right cervical muscle pain scores and the sum of left cervical muscle pain scores showed the highest correlation(r = 0.802, P < 0.001). The sum of right TMD pain scores and the sum of left TMD pain scores were moderately correlated(r = 0.481, P < 0.001). For the twenty patients with unilateral TMD pain, the partial correlation coefficient between the sum of ipsilateral cervical muscle pain scores and the sum of contralateral cervical muscle pain scores was the largest(r = 0.597, P = 0.009). A partial correlation between the sum of primary TMD side pain scores and the sum of ipsilateral cervical muscle pain scores was 0.564(P = 0.015). Conclusions: TMD is associated with cervical muscle pain on condition of pressure pain response to palpation. Of the cervical muscles, sternocleidomastoid and upper trapezius frequently exhibit moderate to severe pressure pain, and they are closely related to the masticatory muscle pain. The characteristic of symmetric involvement of pain is prominent in cervical muscles; however, TMD can affect the level of cervical muscle pain to modify its symmetric nature.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.522-525
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• 2005

The purpose of this study was to analyze the pattern of muscle usage during swing motion with a soft golf club in comparison with that with a normal golf club. The subjects were normal healthy young adults. The subjects performed swing motion using normal and soft golf clubs in turn. Then, we compared and analyzed the muscular activities for the two cases. The muscular activities of the subject was measured using MP100(BIOPAC Systems, Inc.). For the analysis of muscular activities, we measured EMG(Electromyography) of the subjects during swing motion. The muscles analyzed were deltoid, latissimus dorsi, external oblique, and rectus abdominis of the upper limbs and rectus femoris, biceps femoris, gastrocnemius, and soleus of the lower limbs. The result of the experiment showed that the pattern of muscle usage with soft golf club was similar to that with a normal golf club but the muscular activities with the soft golf was smaller than that with the normal golf club.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.8
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• pp.260-267
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• 2018

Surface electromyography (sEMG) is mainly used as an on/off switch in the early stage of the study and was then expanded to navigational control of powered-wheelchairs and recognition of sign language or finger gestures. There are difficulties in communication between people who know and do not know sign language; therefore, many efforts have been made to recognize sign language or finger gestures. Recently, use of sEMG signals to recognize sign language signals have been investigated; however, most studies of this topic conducted to date have focused on Chinese finger number gestures. Since sign language and finger gestures vary among regions, Korean- and Chinese-finger number gestures differ from each other. Accordingly, the recognition performance of Korean finger number gestures based on sEMG signals can be severely degraded if the same muscles are specified as for Chinese finger number gestures. However, few studies of Korean finger number gestures based on sEMG signals have been conducted. Thus, this study was conducted to identify potential forearm muscles from which to collect sEMG signals for Korean finger number gestures. To accomplish this, six Korean finger number gestures from number zero to five were investigated to determine the usefulness of the proposed muscles and electrode placements by showing that CNN technique based on sEMG signal after sufficient learning recognizes six Korean finger number gestures in accuracy of 100%.

• Korean Journal of Childcare and Education
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• v.8 no.5
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• pp.5-24
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• 2012

The purpose of this study was how a nature-friendly fingertips play program with nature affected the development of small muscle functions and creative thinking abilities of young children. The subjects of this study were 28 five year old children. Fourteen of them were from H preschool and the other fourteen were from P preschool in the city of B. The research 'evaluation tool for small muscle motor function development' by Byung Dong Kang(2002) was used to measure the small muscle motor functions of preschool students. The Korean version standardized by Young Chae Kim(2004) was used to measure the development of creative thinking abilities. The study arrived at the following results. First, the nature-friendly fingertips play program affected positively to the development of entire small muscle functions, accuracy, rapidness, and stability for young children. Second, the nature-friendly fingertips play program affected positively to the entire creative thinking abilities, fluency, and resistance to the early conclusion. In conclusion, the nature- friendly fingertips play program affected positively to the development of small motor functions and creative thinking abilities.

• Science of Emotion and Sensibility
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• v.8 no.2
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• pp.161-167
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• 2005

The study is to examine how facial EMG responses change when children experience a positive emotion(happiness) and a negative emotion(fear). It is to prove that the positive emotion(happiness) could be distinguishable from the negative emotion(fear) by the EMG responses. Audiovisual film clips were used for evoking the positive emotion(happiness) and the negative emotion(fear). 47 children (11-13 years old, 23 boys and 24 girls) participated in the study Facial EMG (right corrugator and orbicularis oris) was measured while children were experiencing the positive or negative emotion. Emotional assessment scale was used for measuring children's psychological responses. It showed more than $85\%$ appropriateness and 3.15, 4.04 effectiveness (5 scale) for happiness and fear, respectively. Facial EMG responses were significantly different between a resting state and a emotional state both in happiness and in fear (p<001). Result suggests that each emotion was distinguishable by corrugator and orbicularis oris responses. Specifically, corrugator was more activated in the positive emotion(happiness) than in the negative emotion(fear), whereas orbicularis oris was more activated in the negative emotion(fear) than in the positive emotion(fear).

• Journal of Life Science
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• v.30 no.2
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• pp.202-210
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• 2020

As the elderly population increases, it is becoming important to prevent and treat muscle loss caused by aging or disease. Steroidal androgen in the protein assimilation steroid (AAS) system is mainly used to induce muscle improvement, but it is well known that long-term or excessive doses of AAS result in various side effects, although they are prescribed for various muscle and weight loss treatments. Research is therefore underway to explore natural substances that promote muscle renewal with relatively few side effects. However, despite many studies on the improvement of skeletal muscle and the reduction of muscle disease using natural products, there is still a lack of significant clinical results and mechanism studies. The promotion of muscle regeneration through treatment with natural substances typically involves three mechanisms: positive control of the muscle modulating factor (MRF), activation of the protein synthesis mechanism, and inhibition of the protein breakdown mechanism. A study of plant extracts that are known to have muscle neoplasmic stimulation effects, such as black ginseng, plum, and nutmeg, as well as single substances derived from natural products, such as creatine, catechin, and several fatty acids, is therefore described. We also summarize the mechanisms that have been identified so far through which each of these extracts or single materials facilitates muscle regeneration and the signaling pathways that they mediate.

• Journal of Yeungnam Medical Science
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• v.18 no.2
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• pp.277-286
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• 2001

Background: This study was undertaken to evaluate the diagnostic sensitivity of several muscles in repetitive nerve stimulation test (RNST) for myasthenia gravis (MG) patients. Materials and Methods: The study population consisted of 39 MG patients classified by modified Ossermann's classification. Using Stalberg's method, RNST was systematically performed in facial (orbicularis oculi and nasalis) and upper extremity (flexor carpi ulnaris, abductor digiti quinti and anconeus) muscles. Results: The significant electrodecremental response of RNST were noted in orbicularis oculi(58.9%), nasalis (51.3%), flexor carpi ulnaris(42%), anconeus(41%) and abductor digiti quinti muscles(27%). Among the 3 muscles of upper extremity(abductor digiti quinti, flexor carpi ulnaris and anconeus), the positive electrodecremental response of anconeus muscles was significantly higher than other two muscles(p<0.05) in type IIa, IIb and there were no statistical differences of the positive electrodecremental response between orbicularis oculi and nasalis muscles. The facial muscles showed more prominent decremental responses than upper extremity muscles in type I MG(p<0.05). In type IIa MG patients, there were no significant statistical differences between facial and upper extremity muscles but significant statistical differences among upper extremity muscles. In type IIb MG patients, there were no significant statistical differences in all tested muscles in spite of the increased positive electrodecremental response of RNST. Conclusion: On the basis of this study, RNST would be initially performed for the orbicularis or nasalis in type I MG and for the anconeus in type IIa or IIb MG.

• Journal of Life Science
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• v.23 no.12
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• pp.1509-1515
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• 2013

The term lipotoxicity has been used to describe how excess lipid accumulation leads to cellular dysfunction and death in non-adipose tissues, including skeletal muscle. While lipotoxicity has been found in cultured skeletal muscle cells with high-fat feeding, the consequences of lipotoxicity in vivo are still unknown, particularly in Type-I muscle, which is metabolically affected by lipotoxicity. The aim of this study was to investigate the effects of a high-fat diet on changes in the morphology and apoptotic protein expression of Type-I muscle loss in rats. The rats were fed either a high-fat diet or a normal diet for six weeks, and then lipid accumulation, inflammation response, and nucleus infiltration were measured, and PARP protein expression was cleaved by Oil Red O staining, H & E staining, and Western blot, respectively. Lipid accumulation, inflammation response, nucleus infiltration, and cleaved PARP protein expression were significantly (p<0.05) higher in the high-fat diet group than they were in the normal diet group. The weight of Type-I muscle tended to be lower in the high-fat diet group compared to the normal diet group, but the difference was not statistically significant. These results indicate that a high-fat diet triggers cell death in Type-I muscle via lipotoxicity, which suggests that a high-fat diet may be associated with sarcopenia.