• Journal of Acupuncture Research
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• 제21권2호
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• pp.31-40
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• 2004

목적 : 본 연구는 Interleukin 10 (IL10) 유전자 다형성이 구안와사의 발병과 관련이 있는지 알아보기 위해 수행되었다. 대상: 대구한의대학교부속 한방병원에 내원한 구안와사 환자 62명과 종합건진센터에 내원한 구안와사 기왕력이 없는 건강인 104명을 대상으로 하였다 방법 : 각 그룹에서 개개인마다 DNA를 분리 정제한 후 Taq polymerase로 증폭하여 한천 겔에서 전기영동을 하여 PCR 산물을 확인하였다. PCR 산물은 Pyrosequendng 과정을 통하여 IL10의 유전형이 자동으로 판정되었다. 결과 : A/A, A/C의 두가지 유전자형이 검출되었으며 구안와사군과 대조군 사이에 유의성 있는 차이가 발견되지는 않았다(p=0.052). 또한 개별 allele 빈도에 있어서도 구안와사군과 건강인 사이에 통계적인 유의성이 나타나지 않았다(p=0.064). 결론 : 이상의 결과를 통하여 IL10 유전자 다형성은 구안와사의 발병과는 관련성이 없는 것으로 사려된다. 그러나 더 많은 구안와사 환자를 대상으로 IL10 유전자와의 연관성에 대한 후속 연구가 필요하다고 하겠다.

• 턱관절균형의학회지
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• 제6권1호
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• pp.5-10
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• 2016

본 증례에서는 구안와사환자에게 음양균형장치를 포함한 표준형 구강내 균형장치, 침구치료, 골반교정 등 복합치료를 통해 유효한 임상경과를 보인 결론은 다음과 같다. 1. 안면신경은 주행이 길고 측두골내에서 좁은 골관을 지나기 때문에, 좌상(bruised) 등 여러 가지 이유에 의하여 골도속의 신경 부종과 혈액순환 장애로 지연성 마비를 일으킨다. 2. 음양균형장치와 표준형구강내 균형장치 등 턱관절의 균형조절을 통한 기능적뇌척주요법의 치료가 안면신경마비의 치료에 효과적인 방법인 것을 관찰하였다. 기존의 구안와사의 경우 대부분 뚜렷한 치료방법을 선택하기가 어려웠으나, 이 증례를 통해 볼 때 수술 등의 대증요법을 하지 않고 기능적뇌척주요법 치료의 접근을 시도해 볼 수 있는 가능성이 있다고 사료된다.

• 임상간호연구
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• 제18권1호
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• pp.52-62
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• 2012

Purpose: This study was done to evaluate the effects of Doin Gigong Exercise on the Recovery from Facial Paralysis, pain and anxiety in patients with Bell's palsy. Methods: A nonequivalent control group posttest-only non-synchronized design was used for this study. Participants were contacted at the oriental medicine ward of D hospital in Busan and assigned to either the experimental group (25) or control group (25). Collected data were analyzed for changes in recovery from facial paralysis, in pain and in anxiety between pre and post Doin Gigong Exercise. Data analysis was done using t-test, Fisher's exact test, $x^2-test$ with the SPSS 12.0 Win program. Results: There were significant decreases in the lip paralysis status pain and in anxiety between pre and post Doin Gigong Exercise. Conclusion: The results indicate that Doin Gigong Exercise is effective for patients with Bell's palsy to decrease lip paralysis, pain and anxiety and therefore, an effective intervention for use with patients with Bell's palsy.

• 임상간호연구
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• 제20권2호
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• pp.211-222
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• 2014

Purpose: This study was done to identify the effects of Laughter therapy on recovery status from facial paralysis, pain, and stress in Bell's palsy patients. Methods: This research was a nonequivalent control group non-synchronized pre-posttest quasi-experimental research design. Data were collected from August 8, to October 15, 2013 at D university Oriental Medical Center in B city. Participants were 60 patients with Bell's palsy who were assigned to one of two groups: an experimental group of 30 patients and a control group of 30 patients. t-test, $x^2-test$, Fisher's exact test and Welth-Aspin test were used to test the homogeneity between the two groups and t-test, Welth-Aspin test and ANCOVA were used to test the research hypotheses. SPSS program was used for statistical analysis. Results: There were significant increases in recovery status from facial paralysis and decreases in stress after Laughter therapy in the experimental group. Conclusion: The results indicate that Laughter therapy is effective in facilitating recovery status from facial paralysis and decreasing stress. Therefore, Laughter therapy can be used as an effective nursing intervention for patients with facial paralysis and to relieve stress in these patients.

• Journal of Acupuncture Research
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• 제21권6호
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• pp.111-120
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• 2004

Objective : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea (合穴) points in branches of the twelve meridians(WSBTM) will be representative of measurements of the twelve meridians, to measure the electric potentials of 13 patients with Facial Hemiparalysis (구안와사<口眼蝸斜>, FH), to find out the characteristic of meridian system in patients with AK. Methods : Electric potentials of well and sea points in the meridians in twenty one patients with the pain in the lion diagnosed as FH were repeatedly measured by physiograph(PowerLab). Measurements of those electrical potentials were analyzed by factor analysis. Results : The electric potentials of WSBTM at the left side were divided into five factors. On the other hand those at the right side Were divided into four factors. Conclusions : In conclusion, their electrical potentials at the left and right side were each other five and four factors. Thus electrical potentials of well and sea points might be the representative meridian to show their characteristics.

• Journal of Acupuncture Research
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• 제27권2호
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• pp.155-160
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• 2010

Objectives : The purpose of this study is to investigate the efficacy of Bee venom Pharmarcopuncture on facial palsy in Herpes Zoster otiucus. Methods : We used the acupuncture and Bee venom Pharmarcopuncture complex therapies on facial palsy in Herpes Zoster otiucus occurred in pregnancy. The improvement of the symptom and facial movement was evaluated by VAS and Yanagihara scale. Results & Conclusions : After treatment, both VAS and Yanagihara's scale were significantly improved. In this case, we found that the acupuncture and Bee venom Pharmarcopuncture complex therapy is effective for facial palsy in Herpes Zoster otiucus.

• 대한한방내과학회지
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• 제22권4호
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• pp.573-578
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• 2001

Objective: This study was carried out to investigate the correlation between prognosis and differential temperature of Digital infrared Thermographic Imaging in Bell's palsy. Methods: The clinical data and thermographic images were analyzed on 50 cases of Bell's palsy who were treated ambulatory in Dong-so oriental hospital from October 2000 to May 2001 And 32case were selected who underwent thermographic imaging within 7days of onset. Results: There was no statistic significance between ${\Delta}T$ and the length of treatment, but the length of treatment tends to grow as ${\Delta}T$ increased. The length of treatment was shortest in normal thermal pattern, followed by hyperthermal and hypothermal. Conclusions: According to the results, there was a tendency that ${\Delta}T$ value is proportional to treatment days, although it is not significant statistically.

• 한방안이비인후피부과학회지
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• 제18권2호
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• pp.62-69
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• 2005

Objective: This study is to explore the various aspects of the fatigue perceived by patients with Bell's palsy Method: 33 patients who were diagnosed as Bell's palsy were sequentially interviewed and examined Results: The results were as follows 1. The mean average fatigue score of subjects was $1.79{\pm}0.41$ : the physical fatigue revealed the highest value with a mean of $1.84{\pm}0.50$, followed by neurosensory fatigue with a mean of $1.77{\pm}0.42$, psychological fatigue with a mean score of $1.76{\pm}0.54$. 2. With the respect to the general characteristics of subjects, there were statistically significant differences in the patients' fatigue perception by age and the amount of sleeping time. Conclusions: We needed the further study about the relation between fatigue and Bell's palsy

• Journal of Acupuncture Research
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• 제21권2호
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• pp.103-113
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• 2004

Objective : This study was designed to investigate the relation between the angiotensin converting enzyme(ACE) gene polymorphism and Facial nerve palsy in the Korean population. Methods : This sudy was carried out on 117 Facial nerve palsy patients who were treated in the department of acupuncture & moxibustion, Hospital of Oriental medical college, Kyung-Hee University and 135 healthy control subjects. Blood samples from all subjects were obtaind for DNA extraction. The extracted DNA was amplified by polymerase chain reaction(PCR). PCR products were visualized by 2% agarose gel electrophoresis. Results : The sub-genotypes of ACE gene were II homozygotes, ID heterozygotes, DD homozygotes. While the distribution of ACE polymorphism in control subjects was 33%, 43%, 24%, the distribution of it in Facial nerve palsy patients was 32%, 50%, 18%(II, ID, DD). Thus, there was no significant different between the control and Facial nerve palsy groups. Conclusions : we conclude that there is no significant association between ACE gene polymorphism and Facial nerve palsy in Korean population. However, the findings of this study need to be confirmed in more patients and further studies. Additional epidemiologically based studies of the effects and relationship between ACE or other genes and lifestyles with regard to Facial nerve palsy is required.

• 혜화의학회지
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• 제18권2호
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• pp.89-94
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• 2009

Objective : This study was designed to evaluate the effect of treatment of Bell's palsy patients with postauricural pain by Anti-inflammatory pharmacopuncture Methods : The clinical comparison studies were carried out 30 cases of Bell's palsy patient with postauricular pain. Anti-inflammatory pharmacopuncture. We divided into two groups. One was control group that was treated only Acupuncture and Herbal therapy and The other was a Anti-inflammatory pharmacopuncture group and the conclusions for treatment are as follows. Results : 1. Regarding alleviation of pain by VAS, Anti-inflammatory pharmacopuncture Group II showed significant decrease of VAS in the 5days treatment. 2. They were not significant score within two groups after 5th days treatment. 3. As a result of evaluation by using Yanagihara score, they were not significant score within two groups after final treament.