• Journal of Plant Biotechnology
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• v.46 no.3
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• pp.137-142
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• 2019

Gene edited crops can be classified as SDN-1, SDN-2 and SDN-3 group depending on their mutation's range and the usage of donor DNA. The SDN-1 and SDN-2 crops, in particular, could be developed as 100% transgene-free, which do not contain any DNA fragment of the vector or guide RNA used for gene editing such as CRISPR Cas9 system. Therefore, there are no scientific methods available for the detection of these crops and differentiation with the one produced by conventional cross breeding techniques. Additionally, it would be impossible to properly implement the existing GMO regulation law, in particular, the national legislation for "GMO labelling". In this regard, Australia has announced that SDN-1 crops will not be subjected to the existing GMO regulation. Furthermore, Argentina and Brazil have established a new policy that GE crops with no transgene (100% transgene-free crops) should be exempted from the scope of the GMO. In addition, Japan has also announced that "an organism that has no remnants of inserted nucleic acid processed extracellularly is not subjected to the Cartagena Act". It means that SDN-2 crops can also be exempted from the scope of GMO. In this trend, in South Korea, I suggested that gene edited crops with no remnants of inserted foreign DNA fragments should be excluded from the existing GMO regulation. Thus, I expect that diverse elite crop lines should be developed by using advanced gene editing technologies

• Journal of Life Science
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• v.29 no.1
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• pp.105-111
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• 2019

In recent years, progress has been made in the search for the development of new anti-cancer agents by employing specific inhibitors of histone deacetylase (HDAC)-6 to block signal transduction pathways in cancer cells. This study examined the effects of tubastatin A (TubA), an HDAC-6 inhibitor, on the growth and development of immature oocytes in murine ovaries using RNA sequencing analysis. The results from a gene set enrichment analysis (GSEA) indicated that the expression of most of the gene sets involved in the cell cycle and control and progression of meiosis decreased in the TubA-treated group as compared with that in germinal vesicle (GV) stage oocytes. In addition, an ingenuity pathway analysis (IPA) suggested that TubA not only caused increased expression of p53 and pRB and decreased expression of CDK4/6 and cyclin D but also caused elevated expression of genes involved in the control of the DNA check point in G2/M stage oocytes. These results suggest that TubA may induce cell cycle arrest and apoptosis through the induction of changes in the expression of genes involved in signal transduction pathways associated with DNA damage and the cell cycle of immature oocytes in the ovary.

• Journal of agricultural medicine and community health
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• v.44 no.3
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• pp.115-123
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• 2019

Objective: This study was conducted to examine the effects of a health promotion program on the health condition of rural elderly women implemented at primary health care posts using Korean Frailty Index. Methods: The research was designed a nonequivalent control group pretest-posttest setting. The participants in this study were 50 residents (intervention group: 25, control group: 25) selected from 4 villages 2 primary health care posts in J city Gyeongsangnam-do. The health promotion program was conducted at the primary health care posts twice a week for 12 weeks. This program consisted of basic exercises(Gukseondo + Theraband muscle strength training) and additional activities(including modified Theraband activity, rubber ball exercise, ball massage, nutrition class, singing class). Collected data were analyzed by descriptive statistics, paired t-test, and repeated measures ANOVA with SPSS 21.0. Results: Results of the health promotion program showed that the health conditions(measured by perceived health status, frailty score, upper/lower flexibility, maximum grip strength, dynamic balance test Timed Up and Go) of the experimental group(25) all statistical significantly improved. Conclusion: Study findings indicate that the health promotion program implemented at primary health care posts on rural elderly women is effective and can contribute to a developed health promotion program for local residents in the future.

• Journal of the Korean Data Analysis Society
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• v.20 no.6
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• pp.3201-3209
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• 2018

The purpose of this study was to explore the factors predicting increased usage hours of smartphone among adolescents. Secondary data was analyzed to be collected from a nationally representative sample of 2017 Korean adolescents. This study sample included 54,601 students in middle or high schools of Korea. The collected data were analyzed SPSS version 23.0 program for frequency, percentage, mean, standard deviation, t-test, ANOVA, Pearson's correlation coefficient and binary logistic regression analysis. In the results, the mean usage hour of smartphone among the adolescents was 28.42 (SD 23.30) per week. Analyses of the differences in usage hours of smartphone according to research variables were found that the groups of lower level of study (F=1361.067, p<.001) and sociality content type (F=761.549, p<.001) spent more time, as compared to the other groups. The logistic analysis showed the predictive factors for increased hour of using smartphone were smartphone usage for sociality (OR: 2.44, 95% CI: 2.26-2.64) and peer group counselor (OR: 1.49, 95% CI: 1.49). Conclusionally, the findings of this study suggests that it needs to understand cause or purpose of smartphone using of adolescent and to cope and educate on the cause.

• Journal of the Korea Convergence Society
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• v.12 no.4
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• pp.311-316
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• 2021

The college's beauty department, which has a globalized education system that breaks away from the uniform beauty concept, can dominate in the fierce competition with other schools, and the development and vitalization of the department is guaranteed. In addition, research on the department name is very necessary to establish internal and external PR strategies for affiliated departments and departments and to analyze the direction of realistic beauty education. Accordingly, as a result of analyzing the trends of the department and department name by classifying the universities in Yeonghonam into four regions, the departments belonging to each region of the beauty department showed the most belonging to the natural science and arts and sports departments. In addition, the names of beauty departments by region are Busan and Gyeongnam, Daegu and Gyeongbuk, Gwangju and Jeonnam, and Jeonbuk with 5 beauty departments (29.41%), 3 beauty design schools (13.04%), and 8 beauty and beauty departments. (50.00%), beauty design departments, 2 schools (33.33%). This study makes it possible to cultivate professional beauticians who cultivate an artistic and creative sense that meets the educational goals of beauty education, and it is expected that it will be provided as a very necessary basic data for the division of departments or change of department name according to detailed majors.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.4
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• pp.261-270
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• 2021

Purpose : The purpose of this study is to investigate the effects of sleep duration on stress and depression in college students. The results obtained will be used as a foundational framework for fostering a healthy sleep culture among college students and for formulating measures to improve the quality of their sleep. Ultimately, we intend to produce a publicity and educational material. Methods : For this study, a survey involving 100 college students was conducted, after which data based on a final total of 95 respondents were analyzed. The information on stress and depression were first analyzed in terms of general characteristics and then organized based on the data collected to investigate the effects of sleep duration on stress and depression. The participants were divided into the following groups: "less than 6 hours," "6 to 7 hours," and "7 to 8 hours." BEPSI-K (Brief encounter psychosocial instrument-Korean) was used for stress evaluation, while K-CESD-R (Korean version of center for epidemiologic studies depression scale-revised) was utilized for depression evaluation. Results : First, according to sleep duration, the BEPSI-K scores showed a statistically significant difference in each group (p<.01). In the post-hoc test, there was a difference among the "less than 6 hours" group, the "7 to 8 hours" group. A statistically significant difference was noted (p<.01). In addition, sleep duration had a statistically significant effect on the negative (-) direction of the BEPSI-K (p<.01). Second, the K-CESD-R score according to sleep duration showed a statistically significant difference in each group (p<.01). Notably, in the post-hoc test, the "less than 6 hours" group differed from the "6 to 7 hours" group, "7 to 8 hours" group. A statistically significant difference was noted (p<.01). In addition, sleep duration had a statistically significant effect on the negative (-) direction of the K-CESD-R (p<.01). Third, for the correlation between sleep duration and stress and depression, a negative (-) correlation was found between sleep duration and BEPSI-K and K-CESD-R. Meanwhile, a positive (+) correlation was found between BEPSI-K and K-CESD-R. Conclusion : Based on the findings of this study, the sleep duration of college students has an effect on stress and depression. The results of this study can be used as a foundational framework in formulating a plan for improving the quality of sleep of college students.

• Journal of Digital Convergence
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• v.17 no.11
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• pp.387-394
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• 2019

The purpose of this study was to identify the moderated effects of emotional intelligence on the relationship between transition shock and adaptation on clinical practice among nursing students. Subjects were 185 associate nursing students associate nursing students(3rd). The data were collected using self -report questionnaire from May 1 to June 14, 2019. Data were analyzed by descriptive statistics, t-test, ANOVA, Pearson correlation and hierarchical multiple regression with SPSS/WIN 23.0. Mean point of transition shock(4 point scale) was 2.32. Mean point of emotional intelligence(5 point scale) was 3.61, and adaptation on clinical practice(5 point scale) was 3.40. Transition shock were significantly negative correlation with emotional intelligence(r=-.26. p <.001) and adaptation on clinical practice(r=-.43. p <.001) in nursing students. Emotional intelligence were significantly positive correlation with adaptation on clinical practice(r=.36. p <.001). Emotional intelligence has been shown to modulate the relationship between transition shock shock and adaptation on clinical practice(${\Delta}R^2=0.21$, p <.001). Therefore, to decrease the transition shock and to increase the adaptation on clinical practice of nursing students, It is necessary to develop the program for increase emotional intelligence of nursing students.

• Journal of Life Science
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• v.31 no.1
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• pp.100-108
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• 2021

In the oral cavity, there are hundreds of microbial species that exist as planktonic cells or are incorporated into biofilms. The accumulation and proliferation of pathogenic bacteria in the oral biofilm can lead to caries and periodontitis, which are typical oral diseases. The oral bacteria in the biofilm not only can resist environmental stress inside the oral cavity, but also have a 1,000 times higher resistance to antibiotics than planktonic cells by genes exchange through the interaction between cells in the oral biofilm. Therefore, if the formation of oral biofilm is suppressed or removed, oral diseases caused by bacterial infection can be more effectively prevented or treated. In particular, since oral biofilms have the characteristic of forming a biofilm by gathering several bacteria, quorum sensing, a signaling system between cells, can be a target for controlling the oral biofilm. In addition, a method of inhibiting biofilm formation by using arginine, an alkali-producing substrate of oral bacteria, is used to convert the distribution of oral microorganisms into an environment similar to that of healthy teeth or inhibit the secretion of glucosyltransferase by S. mutans to inhibit the formation of non-soluble glucans. It can be a target to control oral biofilm. This method of inhibiting or removing the oral biofilm formation rather than inducing the death of pathogenic bacteria in the oral cavity will be a new strategy that can selectively prevent or therapeutic avenues for oral diseases including dental caries.

• Journal of Christian Education in Korea
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• v.64
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• pp.237-287
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• 2020

This study was developing group counseling program for sexual education for Christian young adults. and its effects were proven. For this purpose, this study of unmarried Christian young adults ranging 30 from the age 20~35 years old who are attending church C and S located in city of C at Kyungnam province. The subject and control group each had 15 people who separately participated in this program once a week for 120 minutes, 12 times in total. The control group did not receive any feedback after the sessions. group counseling program for sexual education was based on Crabb's biblical counseling model and McMinn's cognitive therapy. Using 12 kinds of cognitive therapy techniques. for its effects were verified. used The sexual knowledge scale standardized model of a college student set by Jeon Gyungsook, Lee Hyoyoung, Lee Seonja, The sexual attitude scale standardized model for a college student set by Ho Seonmin, The sexual decision making scale developed by Sun Mikyung. The data analysis consisted of Cronbach's α test, χ2-test, Mann-Whitney U test, Friedman test, a χ nd Wilcoxon signed-rank test. The result of this study is improve the sexual knowledge, show the conservative tendency of sexual attitudes, and prove the increase in the ability to make responsible sexual decisions of Christian young adults. Following up, this study spreads awareness of the true meaning of sexual being as illustrated from the bible and implies a beneficial program within the church that promotes a healthy life and reconciliation between self, neighbors, and God in a life according to the purpose of creation and order.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.543-552
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• 2021

This study aimed to verify the effectiveness of a recently developed and applied art therapy program. The subjects of the study were twenty-two students at two middle schools in Busan, Korea. Before conducting the study, the parents' agreement was sought, after which the study program was explained to the participating students in private interviews. The twenty-two students were divided into two groups: an experimental group and a control group, with eleven students in each group. Ten sessions of ninety minutes each, twice a week, were conducted for the experimental group. The verification of the effectiveness was done through pre, post, and follow-up examinations. The results of the data analysis are as follows. First, the art therapy program appeared to help reduce suicidal thoughts among those who had them. Second, the art therapy program reduced the depression of adolescents in the study. Third, the art therapy program improved the self-esteem of the study's subjects. In addition, a follow-up examination showed that the effects of the program appear to last. This paper offers proposals for interventions in the suicidal thoughts of adolescents and the practical implication of the interventions and future research paths.