• Archives of Pharmacal Research
• /
• v.28 no.6
• /
• pp.657-659
• /
• 2005

A new biflavonol glycoside named as solanoflavone (1) was isolated from aerial part of Solanum melongena. The chemical structure was elucidated as isorhamnetin-3-O-$\beta$-D-glucopyranoside-(4'$\to$O$\to$4"')-galangin-3"-O-$\to$-D-glucopyranoside on the basis of physicochemical and spectroscopic methods, including 2D NMR spectral techniques.

• Proceedings of the PSK Conference
• /
• 2003.04a
• /
• pp.179.3-180
• /
• 2003

Solanum lyratum (Solanaceae) has been used as a traditional analgesic, antipyretic and hepatoprotective agents in Korea. In this study, we investigated the hepatoprotective effect of ethylacetate extract of Solanum lyratum (SL) on the dimethylnitrosamine (DMN)-induced liver damage in rats. Oral administration of SL (150, 300 mg/kg daily for 4 weeks) into the DMN-treated rats remarkably prevented the elevation of serum alanine transaminase, aspartate transaminase and alkaline phosphatase levels. (omitted)

• Korean Journal of Plant Resources
• /
• v.7 no.2
• /
• pp.149-150
• /
• 1994

The plants medicinal resouces of middle area of Korea were investigated 10 times from May 1, 1993 to November 30. 1994. In order to analyze the vegetation of middle wild plants structure and distribu-tion. Medical wiId plants of middle southern area consisted of 100 familis, 380 specis in all. Theresources of important herb drugs were Polypodiaceae, Graminae, Liliaceae, Polygonaceae,Ranunculaceae, Brassicaceae, Rosaceae, Fabaceae, Apiaceae, Labiatae, Solanaceae, Scrophulariaceae,Campanulaceae, Compositae. The herb drugs were comparatively more than in other mountains in ourcountry.

• Korean Journal of Plant Resources
• /
• v.1 no.1
• /
• pp.93-116
• /
• 1988

The plants medicinal resourees of Mt. Joghe were investigeted 10 times from January, 1988 to October, 1988. In order to analyze the vegetation of Joghemountain area, herb plants structure and distribution. Herb plants of Joghe moun-tain consisted of 102 families, 265 species in all. The resources of important herbdrugs were Gramineae, Cyperaceae Oleaceae, Araceae, Polygonaceae, Caryophyllaceae,Ranunculaceae, Theaceae, Cruciferae, Liliaceae, Rosaceae, Geranjaceae, Violaceae,Vitaceae, Umbelliferae, Labiatae, Solanaceae, Campanulaceae, Rutaceae, Compositae,Dioscoreaceae, Fagaeeae, Moraceae, Anacardiaceae, Legum inosae, Cupressaceae, andJuelandaceae. The herb drugs were comparatively more than in other mountains inour country.

• Bulletin of the Korean Chemical Society
• /
• v.35 no.8
• /
• pp.2529-2532
• /
• 2014

• Archives of Pharmacal Research
• /
• v.28 no.9
• /
• pp.1031-1036
• /
• 2005

[ $(+)-Lyoniresinol-3{\alpha}-O-\beta-D-glucopyranoside$ ] (1) was isolated from an ethyl acetate extract of the root bark from Lycium chinense Miller, and its structure was determined using 1D and 2D NMR spectroscopy including DEPT, HMQC, and HMBC. $(+)-Lyoniresinol-3{\alpha}-O-\beta-D-glucopyranoside$ exhibited potent antimicrobial activity against antibiotic-resistant bacterial strains, methicillin-resistant Staphylococcus aureus (MRSA) isolated from patients, and human pathogenic fungi without having any hemolytic effect on human erythrocytes. In particular, compound 1 induced the accumulation of intracellular trehalose on C. albicans as stress response to the drug, and disrupted the dimorphic transition that forms pseudo-hyphae caused by the pathogenesis. This indicates that $(+)-Lyoniresinol-3{\alpha}-O-\beta-D-glucopyranoside$ has excellent potential as a lead compound for the development of antibiotic agents.

• Natural Product Sciences
• /
• v.3 no.1
• /
• pp.71-74
• /
• 1997

Cell suspension cultures of Solanum mammosum transformed inoculated salicyl alcohol into salicin $(salicyl\;alcohol\;2-0-{\beta}-D-glucopyranoside)$. The highest level of salicin (59.3 mg/flask) in the cells was formed within 3 days after inoculating with salicyl alcohol (50 mg /flask containing 50 ml medium). The glucosylation capability of salicyl alcohol by cell suspension cultures of S. mammosum was relatively higher than that reported previously.

• Natural Product Sciences
• /
• v.2 no.1
• /
• pp.9-13
• /
• 1996

Three new withanolides, designated as withatatulins B, C, and D, were isolated from the fresh flowers of Datura tatula Linn. Detailed spectral analysis of these compounds permitted advancement of their structures respectively, as $5{\beta},6{\beta}-epoxy-12{\beta}$,21-dihydroxy-1-oxo-witha-2,24-dienolide (2), $6{\beta},12{\beta},21-trihydroxy-1-oxowitha$ 2, 4,24-trienolide (3) and $5{\beta},6{\beta},12{\beta}$,21-tetrahydroxy-1-oxo-witha-2,24-dienolide (4a). Withanolides with oxygen functions both at 12 and 21-positions are rare and first reported from Datura species.

• Natural Product Sciences
• /
• v.17 no.2
• /
• pp.104-107
• /
• 2011

In order to facilitate the quality control of betaine from the fruits of Lycium chinense, we have developed a rapid and simple method for quantitative determination. Determination was achieved on a Discovery C18 column with an isocratic solvent system of 0.32% perfluoropentanoic acid aqueous-acetonitrile at a flow-rate of 0.5 mL/min and detected an ELSD. The method was reproducible with intra- and inter-day variations of less than 6% (R.S.D). The recoveries were in the range of 90.01~100.05%. The method turned out to be fast and simple, furthermore, to have a good selectivity and sensitivity for the quantity determination of betaine in the fruits of L.chinense.

• Natural Product Sciences
• /
• v.17 no.3
• /
• pp.181-182
• /
• 2011

Phytochemical investigation of Lycium chinense fruits led to isolation of a new pyrrole compound. The structure of this compound was confirmed as a 5-methoxymethyl-lH-pyrrole-2-carbaaldehyde, a new natural product, by interpretation of 1D ($^1H$, $^{13}C$) and 2D (HMQC, HMBC) spectroscopic data along with HRMS and IR spectroscopic data.