• 대한방사선기술학회지:방사선기술과학
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• 제11권1호
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• pp.17-23
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• 1988

As the reutilizing method of exhausted screen, authors used it as a filter and compared with the aluminium filtration. The results are as followed; 1. One sheet of gadolinium front screen has the same radiation absorption as $2.8{\sim}3.3\;mm$ Al equivalent and regular tungsten screen $2.3{\sim}2.7mm$ Al. 2. HVL after Gd-screen filtration was less than the values after aluminium and tungsten-screen filtration. And, image definition with Gd-screen filtration was better than other two cases. Ana surface dose to produce a same film density was more than other two cases. It will be very useful to apply, Gd-screen filter in clinics as it has no deficiency of image quality.

• Applied Biological Chemistry
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• 제47권1호
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• pp.1-16
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• 2004

이 논문에서는 식품 또는 식품원료 중의 aflatoxin에 관한 오염현황, 최신 분석법 그리고 저감화 시킬 수 있는 방안에 대해 조명하였다. Aflatoxin은 여러 곰팡이가 생성하는 2차 대사산물로서 곰팡이 독소 중 가장 독성이 강한 것으로 알려져 있다. 발암성을 포함한 독성 관계로 aflatoxin은 인간의 건강 측면 뿐 아니라 식품을 포함한 산업전반에 경제적으로 큰 영향을 끼치고 있다. 우리나라와 같은 식량 수입국에서는 식품의 안전성 확보를 위해 노출량 조사, 위해평가 및 관리가 체계적으로 이루어져야 하며 아울러 새로운 aflatoxin 분석 기술의 개발과 독성 저감화 기술의 개발이 병행되어야 한다고 판단된다.

• 수산경영론집
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• 제29권2호
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• pp.143-161
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• 1998

The objective of this study is to analyze the effects of increase in the oyster hatchery on fishermen's income. The results of the analysis are as follows : \circled1 The necessary quantities of oyster seed are 18,000 thousand hanging line. The 29.4%, of that has been applied by ana-seed collection and 29.1% of that has been applied by proseed collection. The demage of oyster aquaculture business is estimated about 35 billion won or 83 billion won. \circled2 The production cost per hanging line of the oyster hatchery is 1,974 won. And if it is sold by 2,500 won, return on investment will be 31.9%. Therefore profitability of the oyster hatchery is very good. \circled3 There are four important determinant variables of profitability to the oyster hatchery. In the order of their effects, it is operation number, seed price, production cost, and quantity of production. \circled4 If differences of price between the artificial hardening oyster seed and the natural hardening oyster seed are more less 1,430 won, the former is better. \circled5 The necessarily quantities of the oyster hatchery are estimated 160 units in the scale of 10,000 hanging line production to one operation. \circled6 The effect of increasing income of fishermen are estimated about 85.3 billion won or 124.5 billion won from increase in the oyster hatchery.

• Biotechnology and Bioprocess Engineering:BBE
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• 제10권5호
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• pp.385-399
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• 2005

The phenotypic response of a cell results from a well orchestrated web of complex interactions which propagate from the genetic architecture through the metabolic flux network. To rationally design cell factories which carry out specific functional objectives by controlling this hierarchical system is a challenge. Transcriptome analysis, the most mature high-throughput measurement technology, has been readily applied In strain improvement programs in an attempt to Identify genes involved in expressing a given phenotype. Unfortunately, while differentially expressed genes may provide targets for metabolic engineering, phenotypic responses are often not directly linked to transcriptional patterns, This limits the application of genome-wide transcriptional analysis for the design of cell factories. However, improved tools for integrating transcriptional data with other high-throughput measurements and known biological interactions are emerging. These tools hold significant promise for providing the framework to comprehensively dissect the regulatory mechanisms that identify the cellular control mechanisms and lead to more effective strategies to rewire the cellular control elements for metabolic engineering.

• BMB Reports
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• 제51권11호
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• pp.563-571
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• 2018

Colorectal cancer (CRC), the third most common cancer in the world, has no specific biomarkers that facilitate its diagnosis and subsequent treatment. The miRNAs, small single-stranded RNAs that repress the mRNA translation and trigger the mRNA degradation, show aberrant levels in the CRC, by which these molecules have been related with the initiation, progression, and drug-resistance of this cancer type. Numerous studies show the microRNAs influence the cellular mechanisms related to the cell cycle, differentiation, apoptosis, and migration of the cancer cells through the post-transcriptionally regulated gene expression. Specific patterns of the upregulated and down-regulated miRNA have been associated with the CRC diagnosis, prognosis, and therapeutic response. Concretely, the downregulated miRNAs represent attractive candidates, not only for the CRC diagnosis, but for the targeted therapies via the tumor-suppressing microRNA replacement. This review shows a general overview of the potential uses of the miRNAs in the CRC diagnosis, prognosis, and treatment with a special focus on the downregulated ones.

• Applied Microscopy
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• 제17권2호
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• pp.55-71
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• 1987

To investigate the effects of lead on the electron transport system and ultrastructure of mouse kidney mitochondria, various lead acetate concentrations were treated in vitro and respiration rate, enzyme activities were measured. Ultrastructural changes at state IV respiration were also observed. To compare with in vivo experiments, mouse were injected intraperitoneally of 100 mg lead acetate per kg body weight and state IV respiration rate and enzyme activities were measured. Ultrastructure of renal proximal tubular cells were also observed. In in vitro treatement, decreased state IV respiration, decreased enzyme activities, ruptured membranes and inhibition of condensed to orthodox transformation were observed. In in vivo treatment, decreased state IV respiration and decreased enzyme activities were observed after 24 hrs of i.p. injection. Cytochrome c oxidase activity showed twice the inhibition compared to NADH-CoQ reductase activity at 24 hrs. Continuous decreased state IV respiration was observed after 48 and 72 hrs of injection, however, the enzyme activities were increased to control level. Lead-protein complex which probably inhibits the toxic effects of lead appeared. To conclude, dominant effect of lead on the electron transport system appeared at cytochrome c oxidase activity, and the increased enzyme activities may be a result of appearance of lead-protein complex.

• Parasites, Hosts and Diseases
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• 제55권1호
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• pp.81-84
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• 2017

Trypanosoma cruzi is the etiological agent of Chagas disease. Epimastigote forms of T. cruzi can be readily cultured in axenic conditions. Ethanol and dimethyl sulfoxide (DMSO) are commonly used solvents employed as vehicles for hydrophobic compounds. In order to produce a reference plot of solvent dependent growth inhibition for T. cruzi research, the growth of epimastigotes was analyzed in the presence of different concentrations of ethanol (0.1-4.0%) and DMSO (0.5-7.5%). The ability of the parasites to resume growth after removal of these solvents was also examined. As expected, both ethanol and DMSO produced a dose-dependent inhibition of cellular growth. Parasites could recover normal growth after 9 days in up to 2% ethanol or 5% DMSO. Since DMSO was better tolerated than ethanol, it is thus recommended to prefer DMSO over ethanol in the case of a similar solubility of a given compound.

• 대한방사선기술학회지:방사선기술과학
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• 제22권1호
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• pp.87-90
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• 1999

Treatment of human calculi by extracorporeal shock-wave lithotripsy(ESWL) was introduced for kidney stones in 1980. This technology was then applied to the treatment of bile duct stones and pancreatic stones. Some reports have also shown that disintegration of pancreatic stones by extracorporeal shock-wave lithotripsy is possible with successful subsequent endoscopic extraction of the fragments at home ana abroad. We tried removal of pancreatic calcification stones by endoscopic procedures, but could't be removed because the basket got entagled in the endoscopy. We report one case of this pancreatic calcification stones ; the stones were successfully fragmented and completely removal by extracorporeal shock-wave lithotripsy.

• 한국재료학회지
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• 제17권1호
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• pp.25-30
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• 2007

The in-situ scanning electron microscopy observation of real-time hillock evolution in pure hi thin films on glass substrate during Isothermal annealing was analyzed quantitatively to understand the compressive stress relaxation mechanism by focusing on the effect of Mo interlayer between Al film and glass substrate. There is a good correlation between the hillock-induced stress relaxation by in-situ scanning electron microscopy observation ana the measured stress relaxation by wafer curvature method. It is also clearly shown that the existence of Mo interlayer plays an important role in hillock formation probably due to the large difference in interfacial diffusivity of Al films.

• Journal of Nutrition and Health
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• 제4권4호
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• pp.69-72
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• 1971

These experiments were designed to study the Hg contents in Korean Hens Egg by origin, kind, organ, and cooking methods. The following samples were studied. Place of origin Seoul (Legon) Su Woun (Legon) Pusan (Legon) Ulsan (Legon) Tae Gu (Legon) Kwang Ju (Legon) Seoul (New Hampson) Seoul (Native) No of sample 12 12 12 10 10 10 10 10 The following result were obtained. 1. The Hg contents of hen's egg of Seoul origin was 0.087 p.p.m., that of Ulsan origin was 0.077 p.p.m.. Its contents of Tae Gu, Kwang Ju origin were 0.052 p.p.m. and 0.048 p.p.m.. High contents of Hg showed in egg that produced in large cityies ana industrial area. 2. For the kind of egg, the Hg contents of Legon kind was 0.087 p.p.m and that of Native kind was 0.031 p.p.m.. Its contents of Legon kind was higher than that, of Native significantly. 3. By the organ of egg, the contents of Hg in egg yolk was 0.064 p.p.m. that showed 87 percent Hg contents of whole egg, and its value of egg white was 0.009 p.p.m.. 4. About cooking methods, the contents of Hg in parboiled egg was 0.007 p.p.m., that of fried egg was 0.015 p.p.m.. Especially the cooked eggs were significantly lower than row eggs in Hg contents.