• International Journal of Control, Automation, and Systems
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• v.4 no.5
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• pp.645-652
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• 2006

In this paper a new type of filter, called the $H_2/H_{\infty}$ FIR filter, is proposed for discrete-time state space signal models. The proposed filter requires linearity, unbiased property, FIR structure, and independence of the initial state information in addition to the performance criteria in both $H_2$ and $H_{infty}$ sense. It is shown that $H_2,\;H_{\infty}$, and $H_2/H_{\infty}$ FIR filter design problems can be converted into convex programming problems via linear matrix inequalities (LMIs) with a linear equality constraint. Simulation studies illustrate that the proposed FIR filter is more robust against temporary uncertainties and has faster convergence than the conventional IIR filters.

• 한국초전도학회:학술대회논문집
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• v.14
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• pp.55-55
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• 2004

• Archives of Pharmacal Research
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• v.24 no.2
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• pp.159-163
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• 2001

The accelerated stability of dimethoxy biphenyl monocarboxylate.HCl (DDB-S) was investigated in 6 mg/mL water solution in the pH ranging 2-10 and the temperature of $45-85^{\circ}C$. The observed rate of degradation followed first-order kinetics. The energy of activation for DDB-S degradation was calculated to be 14.1 and 16.5 $Kcal/mole$ at pH 5 and in distilled watery respectively. The degradation rate constant ($K_{25^{\circ}C}$) obtained by trending line analysis of Arrhenius plots for DDB-S was $5.3{\times}10^{-6}h^{-1}$. The times to degrade 10% ($t_{10}$) and 50% $t_{500}$) at $K_{25^{\circ}C}$ were 829 and 5,416 days, respectively. DDB-S exhibited the fastest degradation at pH 10 and the slowest rate at pH 5. In addition, at $K_{65^{\circ}C}$, degradation rate constants of DDB-S were 0.066, 0.059, 5.460, 32.171, and $1.4{\times}10^{-6}h^{-1}$ at pH 2, 5, 8, 10 and in distilled water, respectively. These observations indicated that the rate-pH profile of DDB-S showed general acid-base catalysis reaction in the range of pH 2-10.

• Korean Journal of Optics and Photonics
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• v.6 no.1
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• pp.45-49
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• 1995

시간 상관 단일 광자 계수법을 사용하여 PVP/C/sub 2/H/sub 5/OH와 PEG/H/sub 2/O 혼합 용매에 위치한 rhodemine 6G 분자의 회전 재배열 시간을 측정하였다. 주어진 온도에서 혼합비를 변화시키면서 측정한 결과, PEG/H/sub 2/O와 PVP/C/sub2/H/sub 5/OH에서 각각 회전 이완 시간이 혼합액의 점성도에 선형적으로 비례하지 않는 것으로 관측되었다. 고분자 주의에 cluster가 형성된다는 관점에서 혼합비에 따른 회전 이완 시간의 변화를 설명하였다.

• Communications of the Korean Mathematical Society
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• v.9 no.4
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• pp.831-836
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• 1994

In this paper we characterize the quasiaffine transforms of quasisubscalar operators. Let H and K be separable, complex Hilbert spaces and L(H,K) denote the space of all linear, bounded operators from H to K. If H = K, we write L(H) in place of L(H,K). A linear bounded operators S on H is called scalar of order m if there is a continuous unital morphism of topological algebras $$ \Phi : C^m_0(C) \to L(H) $$ such that $\Phi(z) = S$, where as usual z stands for identity function on C, and $C^m_0(C)$ stands for the space of compactly supproted functions on C, continuously differentiable of order m, $0 \leq m \leq \infty$.

• Journal of fish pathology
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• v.18 no.3
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• pp.269-276
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• 2005

The concentrations of quinolones (oxolinic acid; OXA, norlloxacin: NRF & ciprofloxacin: CPF) after oral administration of single doses (20 mg/kg B.W.) were investigated in carp (Cyprinus carpio) kept in freshwater at 20-23$^{\circ}C$. The distribution of the drug was studied after treatment. At points timed, from 1 h to 96 hrs after administration, blood (B), liver (L), kidney (K) and muscle (M) from 5 individuals in each group were collected for analyse with microbiological bioassay method. The peak concentrations were measured at 8 h (L), 12 h (B and K) and 24 h (M) after administration regardless of treated drugs. Considerably high concentrations of CPF (13.8-19.6${\mu}g/m{\ell}$) NRF (11.8-16.9${\mu}g/m{\ell}$) and OXA (10.8-13.9 ${\mu}g/m{\ell}$) were revealed during the 24 h. At the last time point of the experiment (96 h), concentrations of all three quinolones were: OXA, 2.3-6.3 ${\mu}g/m{\ell}$ ; NRF, 3.1-4.5 ${\mu}g/m{\ell}$ ; CPF, 3.0-5.5${\mu}g/m{\ell}$ in samples. The concentrations decreased subsequently, indicating a first rapid redistribution, followed by a slow phase of elimination. The steady state was observed in blood (12-36 h), liver (12-96 h) and muscle (36-96 h) after the initiation of treatment with OXA. Concerning the compartmental concentrations, (L, K. and M/B concentration ratio), the fluctuation of the ratio was founded at different time points, among drugs. For CPF, highest tissue ratios were prolonged in the order of L>K>M (0.65-1.2/0.82-0.93/1.0-1.7) during the experiments. On the other hand, NRF presented L>K>M (0.65-1.3/0.86-1.0) till 24 h, but L>M>K (0.89-1.26) at 36-96 h. OXA showed L>K>M (0.95-2.1) at 1-8 h, M>K>L (0.51-1.0) at 12-36 hand M>L>K (1.0-2.3) at 48-96 h, respectively.

• Microbiology and Biotechnology Letters
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• v.33 no.4
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• pp.274-280
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• 2005

Pasteurella multocida is known to cause widespread infections in husbandry. To induce homologous and heterologous immunity against the infections, outer membrane proteins (OMPs) in the envelope of P. multocida are thought to be attractive vaccine candidates. Outer membrane protein H is considered as the major component of OMPs. In this study, a gene for OmpH was isolated from pathogenic P. multocida serogroup A. The gene was composed of 1,047 nucleotides coding 348 amino acids with signal peptide of 20 amino acids. The amino acid composition showed about 80 to 98 per cent sequence homologies among other 10 strains of P. multocida serogroup A, reported so far. A recombinant ompH, from which signal peptide was truncated, was generated using pRSET A to name 'pRSET A/OmpH-F2'. The pRSET A/OmpH-F2 was well expressed in E. coli BL21(DE3). The truncated OmpH was purified using nickel-nitrilotriacetic acid (Ni-NTA) affinity column chromatography. Its molecular weight was registered to be 40 kDa on SDS-PAGE gel. In order to generate immunesera against the OmpH, 50 ug of the protein was intraperitoneally injected into mice three times. The anti-OmpH immuneserum recognized about $5{\times}10^{-2}$ng quantity of the purified OmpH. It can be used for an effective vaccine production to prevent fowl cholera caused by pathogenic P. multocida (Serogroup A).

• Applied Chemistry for Engineering
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• v.16 no.1
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• pp.45-51
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• 2005

$K^+-{\beta}^{{\prime}{\prime}}-Al_2O_3$ in the $K_2O-Li_2O-Al_2O_3$ ternary system was synthesized using aluminum nitrate solution as a starting material. For the synthesis of pure $K^+-{\beta}^{{\prime}{\prime}}-Al_2O_3$, raw materials with chemical composition of $0.84K_2O{\cdot}0.082Li_2O{\cdot}5.2Al_2O_3$ were mixed in solution state. The effects of dispersant and solution-pH were investigated in minimizing the particle size and on the synthesis of pure $K^+-{\beta}^{{\prime}{\prime}}-Al_2O_3$. Ethanol was used for a dispersant, and $NH_4OH$ solution and nitric acid were added for pH adjustment. The solution pH was increased from 1.0 to 7.5 by 0.5 increments. Each sample was calcined at $1200^{\circ}C$ for 2 h and characterized with X-ray diffraction and particle size analyzer. The pH of solution significantly effected both particle size and phase formation, while the addition of ethanol only effected particle size. The synthesis of pure $K^+-{\beta}^{{\prime}{\prime}}-Al_2O_3$ was favored by addition of nitric acid (for pH control).

• Journal of Life Science
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• v.30 no.8
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• pp.713-721
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• 2020

Adipogenesis as a model system is needed to understand the molecular mechanisms of human adipocyte biology and the pathogenesis of obesity, diabetes, and other metabolic syndromes. Many relevant studies have been conducted with a focus on gene expression regulation and intracellular signaling relating to Peroxisome proliferator-activated receptor gamma (PPARγ) and CCAAT/enhancer-binding protein alpha (C/EBPα), which are master adipogenic transcription factors. However, epigenome regulation of adipogenesis by epigenomic modifiers or histone mutations is not fully understood. Histone methylation is one of the major epigenetic modifications on gene expression in mammals, and histone H3 lysine methylation (H3Kme) in particular implicates cell differentiation during various tissue and organ development. During adipogenesis, cell type-specific enhancers are marked by histone H3K4me1 with the active enhancer mark H3K27ac. Mixed-lineage leukemia 4 (MLL4) is a major H3K4 mono-methyltransferase on the adipogenic enhancers of PPARγ and C/EBPα loci. Thus, MLL4 is an important epigenomic modifier for adipogenesis. The repressive mark H3K27me3 is mediated by the enzymatic subunit Enhancer zeste homolog 2 (EZH2) of the polycomb repressive complex 2. EZH2-mediated H3K27 tri-methylation on the Wnt gene increases adipogenesis because WNT signaling is a negative regulator of adipogenesis. This review summarizes current knowledge about the epigenomic regulation of adipogenesis by histone H3 lysine methylation which fundamentally regulates gene expression.

• The Journal of Korean Physical Therapy
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• v.11 no.2
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• pp.1-4
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• 1999

The purpose of this study was to analyze the changes of the muscle strength and length according to the changes of evaluation postures. Subjects of this study were 13 male and 13 female students. 6 evaluation postures were selected for this study(K90H90, K90H45, K90H0, K70H90, K70H45, K70H0 ; K90=knee $90^{\circ}$ flexion, K70=knee $70^{\circ}$ flexion, H90=hip $90^{\circ}$ fleion, H45=hip $45\circ}$ flexion. H0=hip $0^{\circ}$ ). The peak torque and hamstring muscle length(from fibula head to ischial tuberosity) were measured at each postures. The peak torque level was evaluated by make use of the KIN-COM. The results were as follows : 1. The peak torque in male was significantly increased with changes of hip flexion angle but not in female(($90^{\circ}\;>\;45^{\circ}\;>0^{\circ}$). 2. The hamstring length and peat torque in male and female was significantly changed according to the alteration of evaluation postures.