• Title/Summary/Keyword: $S1P_2$

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Analysis of antigenic domain of GST fused major surface protein (p30) fragments of Toxoplasma gondii (융합단백질로 발현된 톡소포자충의 주요막단백질(p30) 절편의 항원성)

  • 남호우;임경심
    • Parasites, Hosts and Diseases
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    • v.34 no.2
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    • pp.135-142
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    • 1996
  • Antigenic domain of jai or surface protein (p30) of Toxoplosmc Sondii was analyzed after polymerase chain reaction (PCR) of its gene fragments. Hydrophilic or hydrophobic moiety of amino acid sequences were expressed as glutathione S-transferase (G57) fusion proteins. Fragments of p30 gene were as follows: 737, total p30 open reading frame (ORF) ; S28, total ORF excluding N-terminal signal sequence and C-terminal hydrophobic sequence; Al9, N-terminal 2/3 parts of A28; A19, N-terminal 2/3 of S28; P9, C-terminal 2/3 part of S28; Z9. middle 1/3 of S28; and 29, C-terminal 1/3 of S28. respectively. Primer of each fragment was synthesized to include clamp sequence of EcoR I restriction site. PCR amplified DNA was inserted info GST (26 kDa) expression vector, PGEX-47-1 to transform into Escheri,hia coei (.JM105 strain). G57 fusion proteins were expressed with IPTG induction as 63. 54, 45, 45, 35, 36. and 35 kDa proteins measured by SDS-PAGE. Each fusion protein was confirmed with G57 detection kit. Western blot analysis with the serum of a toxoplasmosis patient revealed antigenicity in proteins expressed by T37. S28, and Al9 but not those by Pl8. X9, Y10, and Z9. Antigenicity of p30 seems to be located either in N-terminal 115 part in the presence of middle 1/3 part or in the oligopeptides between margins of the first and second 1/3 parts.

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Effect of Dietary Supplementation of Paprika and Spirulina on Pigmentation of Swiri Coreoleuciscus splendidus (사료내 paprika 및 spirulina 첨가가 쉬리(Coreoleuciscus splendidus) 표피 색택에 미치는 영향)

  • Kim, Suk-Ree;Lee, Choong-Ryul;Lee, Sang-Min
    • Journal of Aquaculture
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    • v.19 no.4
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    • pp.261-266
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    • 2006
  • This study was conducted to evaluate the effect of dietary supplementation of paprika and spirulina as carotenoid sources with three different levels on survival and skin color development of swiri. Fish (initial mean weight 4.4 g) were fed the diets containing different levels of paprika (2, 5 and 10%), spirulina (5, 10 and 20%) and mixture of 5% paprika and 10% spirulina and without supplementation (con) for 9 weeks. Survival of fish fed diets containing the various levels of spirulina was 100% and higher than that of fish fed the other diets. Total carotenoid contents of the skin and fin in fish fed the diets containing the various levels of paprika and spirulina were higher than those in fish fed the control diet. Total carotenoid contents of skin and fin in fish fed the diets containing 5% and 10% paprika tended to be higher than that in fish fed the diet containing 2% paprika. Total carotenoid contents of fish fed the diets containing 10% and 20% spirulina tended to be higher than that of fed the diet containing 5% spirulina. The apparent color definition of skin and fin in fish fed the diets containing paprika and spirulina was better than fish fed the control diet. The results of this study suggest that dietary supplementation with paprika and spirulina can improve skin coloration of swiri.

${\mathfrak{A}}$-GENERATORS FOR THE POLYNOMIAL ALGEBRA OF FIVE VARIABLES IN DEGREE 5(2t - 1) + 6 · 2t

  • Phuc, Dang Vo
    • Communications of the Korean Mathematical Society
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    • v.35 no.2
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    • pp.371-399
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    • 2020
  • Let Ps := 𝔽2[x1, x2, …, xs] = ⊕n⩾0(Ps)n be the polynomial algebra viewed as a graded left module over the mod 2 Steenrod algebra, ${\mathfrak{A}}$. The grading is by the degree of the homogeneous terms (Ps)n of degree n in the variables x1, x2, …, xs of grading 1. We are interested in the hit problem, set up by F. P. Peterson, of finding a minimal system of generators for ${\mathfrak{A}}$-module Ps. Equivalently, we want to find a basis for the 𝔽2-graded vector space ${\mathbb{F}}_2{\otimes}_{\mathfrak{A}}$ Ps. In this paper, we study the hit problem in the case s = 5 and the degree n = 5(2t - 1) + 6 · 2t with t an arbitrary positive integer.

REPEATED-ROOT CONSTACYCLIC CODES OF LENGTH 2ps OVER GALOIS RINGS

  • Klin-eam, Chakkrid;Sriwirach, Wateekorn
    • Bulletin of the Korean Mathematical Society
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    • v.56 no.1
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    • pp.131-150
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    • 2019
  • In this paper, we consider the structure of ${\gamma}$-constacyclic codes of length $2p^s$ over the Galois ring $GR(p^a,m)$ for any unit ${\gamma}$ of the form ${\xi}_0+p{\xi}_1+p^2z$, where $z{\in}GR(p^a,m)$ and ${\xi}_0$, ${\xi}_1$ are nonzero elements of the set ${\mathcal{T}}(p,m)$. Here ${\mathcal{T}}(p,m)$ denotes a complete set of representatives of the cosets ${\frac{GR(p^a,m)}{pGR(p^a,m)}}={\mathbb{F}}p^m$ in $GR(p^a,m)$. When ${\gamma}$ is not a square, the rings ${\mathcal{R}}_p(a,m,{\gamma})=\frac{GR(p^a,m)[x]}{{\langle}x^2p^s-{\gamma}{\rangle}}$ is a chain ring with maximal ideal ${\langle}x^2-{\delta}{\rangle}$, where ${\delta}p^s={\xi}_0$, and the number of codewords of ${\gamma}$-constacyclic code are provided. Furthermore, the self-orthogonal and self-dual ${\gamma}$-constacyclic codes of length $2p^s$ over $GR(p^a,m)$ are also established. Finally, we determine the Rosenbloom-Tsfasman (RT) distances and weight distributions of all such codes.

Effect of House Dust Mite and CCL2 on S100A8 and S100A9 Expression in Human Monocytes

  • Kim, In Sik;Kim, Eun Hye;Kim, Do Hyung;Kim, Jung Seok;Lee, Ji-Sook
    • Biomedical Science Letters
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    • v.19 no.4
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    • pp.344-347
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    • 2013
  • The S100A8 and S100A9 proteins play important roles in inflammatory diseases. The house dust mite acts as a major allergen that induces allergic diseases. We investigated the effect of the house dust mite on S100A8 and S100A9 protein expression in monocytes. We also examined the effect of CCL2, a powerful monocyte chemoattractant, on the expression of both proteins. Extract of Dermatophagoides pteronissinus (DP), recombinant Der p 1 and Der p 2, or CCL2 had no effect on S100A8 and S100A9 expression in human monocytic THP-1 cells. Monocytes were isolated from healthy donors and treated with DP, Der p 1, and Der p 2. S100A8 expression in monocytes increased after a 24 h stimulation with DP, Der p 1, and Der p 2, and CCL2 also increased S100A8 production. However, S100A9 expression in monocytes was not altered by DP, Der p 1, Der p 2, or CCL2. These results indicate that house dust mite and CCL2 may trigger an inflammatory response by altering S100A8 expression.

Clinical Analysis Of Ventricular Septal Defect (심실중격결손증의 외과적 고찰)

  • Seong, Suk-Hwan;Suh, Kyung-Pill
    • Journal of Chest Surgery
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    • v.15 no.1
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    • pp.90-97
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    • 1982
  • Two hundred one patients of ventricular septal defect, which were operated at Seoul National University Hospital, were analysed on clinical background during the period from January, 1975 to December, 1980. The results were as follows: 1. Of the 201 patients, 118 patients were male [58.7%] and 83 patients were female [41.3%]. Their age ranged from 15 months to 40 years, and the mean age was 8.7 years. 40% of the patients were between 4 and 8 years. 2. The most common symptoms showed frequent U RI and exertional dyspnea. 3. On Kirklin`s anatomical classification, type I constituted 26.9%, type II 58.2%, type III 12.4%, and type IV 1.0%. We showed marked increased incidence of type I VSD as compared to Caucasians* 4. 46 cases were associated with other congenital cardiac diseases. They were PDA [13 cases], AI[11 ], ASD[6], PS[10], MI[4], and Double aortic arch [1]. 5. In 128 patients, who had complete hemodynamic data and were not associated with other congenital cardiac diseases, an attempt was made to correlate the EKG findings with the hemodynamic data, and defect size with the hemodynamic data. The children had variable distribution of PA syst. pr. and Rp/Rs. But most of adults had $R_P$/$R_S$of 0.15 or less. As $P_P$/$P_S$increased, the rate of operative complication increased also. 6. When a normal EKG pattern was present, $Q_P$/$Q_S$and $R_P$/$R_S$and $P_P$/$P_S$were relatively low. When EKG findings were LVH pattern, there was diastolic volume overload to left ventricle. As RVH, there was systolic pressure overload to right ventricle. And as BVH, there was mixed pattern of diastolic volume overload to left ventricle and systolic pressure overload to right ventricle. 7. Among patients in defect was less than 1 $cm^2$ per $M^2$ of BSA, $Q_P$/$Q_S$was less than 2:1, and $R_P$/$R_S$less than 0.25, and PAsyst. pr. less than 50 mmHg, and $P_P$/$P_S$was less than 0.5. But patients with the defect greater than 1 $cm^2$ per $M^2$ of BSA had no correlationship between $Q_P$/$Q_S$, $R_P$/$R_S$, PAsyst. pr. and defect size in each other. Most of patients with the defect greater than 2 $cm^2$/$M^2$ BSA, $R_P$/$R_S$was greater than 0.5. 8. Operative mortality rate was 9.5% [19 cases] among 201 patients. And complication rate including mortality rate was 22.9% [46 cases].

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Synthesis and Antimicrobial Screening of Some Fluorinated Azoles Containing (2-(6-Methyl-2-P-tolyl-lH-imidazo[1,2-a]pyridin-3-yl) Nucleus ((2-(6-Methyl-2-P-tolyl-lH-imidazo[1,2-a]pyridin-3-yl)핵종을 가지고 있는 불소화된 아조화합물의 합성과 항균활성의 스크리닝)

  • Shelke, Sharad;Salunkhe, Nilesh;Sangale, Sandeep;Bhalerao, Swapnil;Naik, Nilesh;Mhaske, Ganesh;Jadhav, Ranjana;Karale, Bhausaheb
    • Journal of the Korean Chemical Society
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    • v.54 no.1
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    • pp.59-64
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    • 2010
  • The synthesis of a series of fluorinated thiadiazoles 3, triazoles 4 and oxadiazoles 5 are synthesized from thiosemicarbazides 2 containing (2-(6-methyl-2-p-tolyl-lH-imidazo[1,2-a]pyridin-3-yl nucleus. These reactions were carried out by conventional method as well as ultra sound irradiation method. All products have been characterized by IR, 1H NMR, MS study and screened for their antimicrobial activity.

PAIR MEAN CORDIAL LABELING OF GRAPHS OBTAINED FROM PATH AND CYCLE

  • PONRAJ, R.;PRABHU, S.
    • Journal of Applied and Pure Mathematics
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    • v.4 no.3_4
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    • pp.85-97
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    • 2022
  • Let a graph G = (V, E) be a (p, q) graph. Define $${\rho}\;=\;\{\array{{\frac{p}{2}}&p\text{ is even}\\{\frac{p-1}{2}}\;&p\text{ is odd,}}$$ and M = {±1, ±2, ⋯ ± 𝜌} called the set of labels. Consider a mapping λ : V → M by assigning different labels in M to the different elements of V when p is even and different labels in M to p - 1 elements of V and repeating a label for the remaining one vertex when p is odd. The labeling as defined above is said to be a pair mean cordial labeling if for each edge uv of G, there exists a labeling $\frac{{\lambda}(u)+{\lambda}(v)}{2}$ if λ(u) + λ(v) is even and $\frac{{\lambda}(u)+{\lambda}(v)+1}{2}$ if λ(u) + λ(v) is odd such that ${\mid}\bar{\mathbb{S}}_{{\lambda}_1}-\bar{\mathbb{S}}_{{\lambda}^c_1}{\mid}{\leq}1$ where $\bar{\mathbb{S}}_{{\lambda}_1}$ and $\bar{\mathbb{S}}_{{\lambda}^c_1}$ respectively denote the number of edges labeled with 1 and the number of edges not labeled with 1. A graph G for which there exists a pair mean cordial labeling is called a pair mean cordial graph. In this paper, we investigate the pair mean cordial labeling of graphs which are obtained from path and cycle.

ON PAIR MEAN CORDIAL GRAPHS

  • R. PONRAJ;S. PRABHU
    • Journal of Applied and Pure Mathematics
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    • v.5 no.3_4
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    • pp.237-253
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    • 2023
  • Let a graph G = (V, E) be a (p, q) graph. Define $${\rho}=\{\array{{\frac{p}{2}} & \;\;p\text{ is even} \\ {\frac{p-1}{2}} & \;\;p\text{ is odd,}$$ and M = {±1, ±2, … ± ρ} called the set of labels. Consider a mapping λ : V → M by assigning different labels in M to the different elements of V when p is even and different labels in M to p - 1 elements of V and repeating a label for the remaining one vertex when p is odd. The labeling as defined above is said to be a pair mean cordial labeling if for each edge uv of G, there exists a labeling ${\frac{{\lambda}(u)+{\lambda}(v)}{2}}$ if λ(u) + λ(v) is even and ${\frac{{\lambda}(u)+{\lambda}(v)+1}{2}}$ if λ(u) + λ(v) is odd such that ${\mid}{\bar{{\mathbb{S}}}}_{\lambda}{_1}-{\bar{{\mathbb{S}}}}_{{\lambda}^c_1}{\mid}{\leq}1$ where ${\bar{{\mathbb{S}}}}_{\lambda}{_1}$ and ${\bar{{\mathbb{S}}}}_{{\lambda}^c_1}$ respectively denote the number of edges labeled with 1 and the number of edges not labeled with 1. A graph G for which there exists a pair mean cordial labeling is called a pair mean cordial graph. In this paper, we investigate the pair mean cordial labeling behavior of few graphs including the closed helm graph, web graph, jewel graph, sunflower graph, flower graph, tadpole graph, dumbbell graph, umbrella graph, butterfly graph, jelly fish, triangular book graph, quadrilateral book graph.

A DOUBLE INTEGRAL CHARACTERIZATION OF A BERGMAN TYPE SPACE AND ITS MÖBIUS INVARIANT SUBSPACE

  • Yuan, Cheng;Zeng, Hong-Gang
    • Bulletin of the Korean Mathematical Society
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    • v.56 no.6
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    • pp.1643-1653
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    • 2019
  • This paper shows that if $1<p<{\infty}$, ${\alpha}{\geq}-n-2$, ${\alpha}>-1-{\frac{p}{2}}$ and f is holomorphic on the unit ball ${\mathbb{B}}_n$, then $${\int_{{\mathbb{B}}_n}}{\mid}Rf(z){\mid}^p(1-{\mid}z{\mid}^2)^{p+{\alpha}}dv_{\alpha}(z)<{\infty}$$ if and only if $${\int_{{\mathbb{B}}_n}}{\int_{{\mathbb{B}}_n}}{\frac{{\mid}f(z)-F({\omega}){\mid}^p}{{\mid}1-(z,{\omega}){\mid}^{n+1+s+t-{\alpha}}}}(1-{\mid}{\omega}{\mid}^2)^s(1-{\mid}z{\mid}^2)^tdv(z)dv({\omega})<{\infty}$$ where s, t > -1 with $min(s,t)>{\alpha}$.