• Title/Summary/Keyword: $K^{+}$ channels

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Culture of the Olive Flounder, Paralichthys olivaceus in a Marine Recirculating System (해수 순환 여과 사육 시스템에서 넙치 사육 시험)

  • Bang, Jong-Deuk;Choi, Yong-Suk;Seo, Hyung-Chul
    • Journal of fish pathology
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    • v.18 no.1
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    • pp.91-97
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    • 2005
  • Bio-secure culture of olive flounder Paralichthys olivaceus in the IBK (Intensive Bioproduction Korean) recirculating system with dry pellet was tested for 6 months. The IBK system consists of 12 rearing tanks, 6 sedimentation tanks. 4-sectioned submerged biofilter chamber and channels. The size of each rearing tank was 3m in diameter and 1m in depth. The size of each biofilter chamber was $3.1\times3.3\times2.0$ m (D) and was filled with corrugated plastic plates as a biofilter medium. Total surface area of the biofilter was 3,789.7 $m^2$ Water was circulated by one of two vertical axial pump and circulating rate was about 34 times per day. A UV light sterilizer was used to treat inlet sea water with the flow rate of 4 ton/hr. All fish were treated with 150 ppm formalin 3 times with 5 day interval before stocking. It took 60 days for 'conditioning' the biofilter with the stocking density of 4.5 kg of fish $m^2$. The concentrations of ammonium-nitrogen, nitrite-nitrogen and nitrate-nitrogen in the system remained at the range of 0.096-0.315 mg/L, 0.015-0.504 mg/L, and 2.530-39.517 mg/L, respectively. Water temperature fluctuated from 17.5 to 25.1$^{\circ}C$ and salinity was from 30.1 to 33.5 ppt during rearing period. The fish grew from the average weight of 615.2 g to 1,201.1 g for 180 days. Initial and final fish densities were 8.4 and 15.9$kg/m^2$, Survival rate was 97.1 %. Neither parasites nor noticeable diseases was observed during the raring period even Vibrio spp. were detected from some fish in the system.

Study on analysis of the Corporate requirements and CPND Value chain for e-book Market Activation (전자책 시장 활성화를 위한 기업 요구사항과 CPND 가치사슬 분석)

  • Na, Yun-Bin;Yu, Jong-Sun;Lee, Seoung-Ha
    • Journal of Digital Convergence
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    • v.14 no.4
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    • pp.163-171
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    • 2016
  • This study derived the policy implications and market strategies by analysis the e-book companies requirements & the CPND value chain structure, in order to revitalize the e-book market in Korea. Specifically, we examined the prospect of e-book market in Korea, current situations of production and distribution, awareness of service utilization and requirements for support policy with targets of 30 companies. As a research, the most needed item for e-book companies is 'PR and marketing support to enter and open the markets'(27%), which is the highest. 'Financial support such as labor costs and business expenses', 'support for retraining personnel to develop the expertise in respective fields' are followed and they account for 22%. Currently, the most effective support item is the external support program(35%) and funding power(30%) is followed. Unlike a paper book market, e-book is turned into a platform business in terms of the value chain. Based on these research content, e-book market activation and corporate competitive strategy was derived as follows : 1)literacy reinforcement about SNS marketing and e-pub3 authoring tool. 2)statistical DB construction of retail sales channels. 3)diversification of the billing system. 4)The quality of the e-book content certification.

Different Responses to Acupuncture in Electroencephalogram according to Stress Level: A Randomized, Placebo-Controlled, Cross-Over Trial (스트레스 정도에 따라 침 치료가 뇌파(EEG)에 미치는 영향: 무작위배정 플라시보 대조군 교차연구)

  • Kim, Song-Yi;Kim, Sang-Woo;Park, Hi-Joon
    • Korean Journal of Acupuncture
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    • v.31 no.3
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    • pp.136-145
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    • 2014
  • Objectives : The purpose of this randomized, placebo-controlled, cross-over trial was to examine how acupuncture treatment at Shinmun(HT7) affects the brain activity and the autonomic nervous system(ANS), using electroencephalograms(EEG) and heart rate variability(HRV). Methods : Eighteen healthy volunteers participated in two separate experiments: in each experiment, either real acupuncture(RA) or non-penetrating sham acupuncture(SA) was applied at HT7 in random sequences to each person. The EEG and HRV measurements were conducted simultaneously before and during the acupuncture stimulation for 5 minutes, respectively. Resulting EEG and HRV parameters were compared between RA and SA groups. To assess differences according to the stress levels for participants, subgroup analysis was performed based on the results of the stress response index questionnaire. Results : In the results, acupuncture stimulation at HT7 increased ${\alpha}$ band in EEG. In the HRV analysis, heart rate was decreased significantly but HF and RMS-SD were increased in the RA group, compared with those of the SA group. In the subgroup analysis by stress level, participants in the RA group with high stress exhibited an increased in ${\alpha}$ band in their EEG while the low stress participants showed decrease or little increase in the band. For the SA group, ${\alpha}$ band reported relatively moderate changes in all channels. Conclusions : Our results showed that acupuncture induces changes in brain activation and the ANS. Acupuncture was related to the activation of the parasympathetic nervous system. The brain activities of the participants were different depending on the stress level.

Inhibition of L-type Ca2+ current by ginsenoside Rd in rat ventricular myocytes

  • Lu, Cheng;Sun, Zhijun;Wang, Line
    • Journal of Ginseng Research
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    • v.39 no.2
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    • pp.169-177
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    • 2015
  • Background: Ginsenoside Rd (GSRd), one of the most abundant ingredients of Panax ginseng, protects the heart via multiple mechanisms including the inhibition of $Ca^{2+}$ influx.We intended to explore the effects of GSRd on L-type $Ca^{2+}$ current ($I_{Ca,L}$) and define the mechanism of the suppression of $I_{Ca,L}$ by GSRd. Methods: Perforated-patch recording and whole-cell voltage clamp techniques were applied in isolated rat ventricular myocytes. Results: (1) GSRd reduced $I_{Ca,L}$ peak amplitude in a concentration-dependent manner [half-maximal inhibitory concentration $(IC_{50})=32.4{\pm}7.1{\mu}mol/L$] and up-shifted the current-voltage (I-V) curve. (2) GSRd ($30{\mu}mol/L$) significantly changed the steady-state activation curve of $I_{Ca,L}$ ($V_{0.5}:-19.12{\pm}0.68$ vs. $-6.26{\pm}0.38mV$; n = 5, p < 0.05) and slowed down the recovery of $I_{Ca,L}$ from inactivation [the time content (${\zeta}$) from 91 ms to 136 ms, n = 5, p < 0.01]. (3) A more significant inhibitive effect of GSRd ($100{\mu}mol/L$) was identified in perforated-patch recording when compared with whole-cell recording [$65.7{\pm}3.2%$ (n = 10) vs. $31.4{\pm}5.2%$ (n = 5), p < 0.01]. (4) Pertussis toxin ($G_i$ protein inhibitor) completely abolished the $I_{Ca,L}$ inhibition induced by GSRd. There was a significant difference in inhibition potency between the two cyclic adenosine monophosphate elevating agents (isoprenaline and forskolin) prestimulation [$55{\pm}7.8%$ (n = 5) vs. $17.2{\pm}3.5%$ (n = 5), p < 0.01]. (5) 1H-[1,2,4]Oxadiazolo[4,3-a]-quinoxalin-1-one (a guanylate cyclase inhibitor) and N-acetyl-$\small{L}$-cysteine (a nitric oxide scavenger) partly recovered the $I_{Ca,L}$ inhibition induced by GSRd. (6) Phorbol-12-myristate-13-acetate (a protein kinase C activator) and GF109203X (a protein kinase C inhibitor) did not contribute to the inhibition of GSRd. Conclusion: These findings suggest that GSRd could inhibit $I_{Ca,L}$ through pertussis toxin-sensitive G protein ($G_i$) and a nitric oxide-cyclic guanosine monophosphate-dependent mechanism.

Satellite Remote Sensing to Monitor Seasonal Horizontal Distribution of Resuspended Sediments in the East China Sea (위성원격탐사에 의한 동중국해 재부상 부유사의 계절적 수평분포 특성)

  • Lee, Na-Kyung;Suh, Young-Sang;Kim, Young-Seup
    • Journal of the Korean Association of Geographic Information Studies
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    • v.6 no.3
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    • pp.151-161
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    • 2003
  • The spatiotemporal distribution of resuspended solid on the shelf of the southern Yellow Sea and the northern East China Sea was studied. The sea surface reflectance imageries obtained by remote sensing using satellite at channels of red (620~670nm), green(545~565nm) and blue(459~479nm) from Terra MODIS were used to explain the front of the high concentration suspended solid(SS) on the shelf in the East China Sea. The horizontal distribution of the resuspended solid was depended on the wind force, tidal current and stratification of water. The horizontal distribution areas of the resuspended solid in winter season during January~April, 2002 were three times wider than those in summer season during June~September, 2001.

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QoS-Guaranteed IP Mobility Management For Fast Moving Vehicles Using Multiple Tunnels (멀티 터널링을 이용한 고속 차량에서 QoS 보장 IP 이동성 관리 방법)

  • Chun, Seung-Man;Nah, Jae-Wook;Park, Jong-Tae
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.48 no.11
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    • pp.44-52
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    • 2011
  • In this article, we present a QoS-guaranteed IP mobility management scheme of Internet service for fast moving vehicles with multiple wireless network interfaces. The idea of the proposed mechanism consists of two things. One is that new wireless connections are established to available wireless channels whenever the measured data rate at the vehicle equipped with mobile gateway drops below to the required data rate of the user requirement. The other is that parallel distribution packet tunnels between an access router and the mobile gateway are dynamically constructed using multiple wireless network interfaces in order to guarantee the required data rate during the mobile gateway's movement. By doing these methods, the required data rate of the mobile gateway can be preserved while eliminating the possible delay and packet loss during handover operation, thus resulting in the guaranteed QoS. The architecture of the IETF standard HMIPv6 has been extended to realize the proposed scheme, and detailed algorithms for the extension of HMIPv6 has been designed. Finally, simulation has been done for performance evaluation, and the simulation results show that the proposed mechanism demonstrates guaranteed QoS during the handover with regard to the handover delay, packet loss and throughput.

A Nulling Anti-Jamming Scheme for the Polyphase Filter Bank-Based Satellite Repeat System (다상 필터 뱅크 기반의 위성 중계시스템을 위한 항재밍 기법의 연구)

  • Oh, Jin-O;Im, Sung-Bin;Ko, Hyun-Suk
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.49 no.7
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    • pp.39-47
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    • 2012
  • The combination of the broadband property and the wide area coverage of satellite communications enables high speed transmission. Every user in the region under the satellite beam coverage can tranceiver and one can simultaneously communicate with multiple users. For these reasons, it is one of commendable telecommunication networks for information transfer. Since the satellite communications use open channels, it is likely to cause jamming with unwanted interference signals. In the thesis, APSK (Amplitude Phase Shift Keying) is employed, which is recommended for DVB-S2 due to high-speed transmission and excellent bandwidth efficiency. For obtaining reliable communication under the jamming environments, the communication satellite transponder rests on the polyphase filter bank structure, which enables switching among the subchannels and gain control on each subchannel, resulting in effectively eliminating jamming. Furthermore, the nulling scheme, one of the various anti-jamming approaches, is investigated, in which unwanted jamming signals are eliminated in the frequency domain after passing through the analysis part of the polyphase filter bank. The performance of the nulling scheme is evaluated for tone jamming and partial band jamming in terms of BER and EVM. The simulation results indicate that the nulling scheme improve the BER and EVM performance over the case without any anti-jamming approach.

Programmed APTES and OTS Patterns for the Multi-Channel FET of Single-Walled Carbon Nanotubes (SWCNT 다중채널 FET용 표면 프로그램된 APTES와 OTS 패턴을 이용한 공정에 대한 연구)

  • Kim, Byung-Cheul;Kim, Joo-Yeon;An, Ho-Myoung
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.8 no.1
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    • pp.37-44
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    • 2015
  • In this paper, we have investigated a selective assembly method of single-walled carbon nanotubes (SWCNTs) on a silicon substrate using only photolithographic process and then proposed a fabrication method of field effect transistors (FETs) using SWCNT-based patterns. The aminopropylethoxysilane (APTES) patterns, which are formed for positively charged surface molecular patterns, are utilized to assemble and align millions of SWCNTs and we can more effectively assemble on a silicon (Si) surface using this method than assembly processes using only the 1-octadecyltrichlorosilane (OTS). We investigated a selective assembly method of SWCNTs on a Si surface using surface-programmed APTES and OTS patterns and then a fabrication method of FETs. photoresist(PR) patterns were made using photolithographic process on the silicon dioxide (SiO2) grown Si substrate and the substrate was placed in the OTS solution (1:500 v/v in anhydrous hexane) to cover the bare SiO2 regions. After removing the PR, the substrate was placed in APTES solution to backfill the remaining SiO2 area. This surface-programmed substrate was placed into a SWCNT solution dispersed in dichlorobenzene. SWCNTs were attracted toward the positively charged molecular regions, and aligned along the APTES patterns. On the contrary, SWCNT were not assembled on the OTS patterns. In this process, positively charged surface molecular patterns are utilized to direct the assembly of negatively charged SWCNT on SiO2. As a result, the selectively assembled SWCNT channels can be obtained between two electrodes(source and drain electrodes). Finally, we can successfully fabricate SWCNT-based multi-channel FETs by using our self-assembled monolayer method.

Influence of Country-of-Origin Image, Brand Attitude and Corporate Social Responsibility on Chinese Consumers' Perceived Quality and Purchase Intention (원산지 이미지, 브랜드 태도, 기업의 사회적 책임이 중국 소비자의 지각된 품질과 구매의도에 미치는 영향)

  • Kim, Bo-Young;Lee, Ga-Young;Song, Ni-Eun
    • Management & Information Systems Review
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    • v.36 no.3
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    • pp.1-16
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    • 2017
  • As purchasing power of Chinese consumers has increased and their purchase channels have become more various, Chinese consumers are paying more attention to foreign products and purchasing more of them as well as the domestic goods. With great expectations, many companies in different nations are scrambling into the Chinese market. In this situation, Chinese consumers have a wider range of choices when selecting and purchasing goods, thereby trying to take several factors into account in order to choose the best one in a limited time. This study is about how much country-of-origin image, brand attitude and corporate social responsibility influence Chinese consumers' quality perception and their purchase decisions. The study result shows that country-of-origin image, brand attitude and corporate social responsibility all have a positive effect on perceived quality of the consumers, and among those three, the brand attitude is found to be the most influential factor. It also shows that perceived quality brings a positive effect on purchase intention. Also, in terms of difference in product categories, the influence of corporate social responsibility on perceived quality and the influence of perceived quality on purchase intention are shown greater in dairy products than in PC. This study has academic significance as it has investigated consumer behavior, considering each different factor above. Also it has practical significance since it offers an implication on the marketing strategies of the companies that are planning to advance into the Chinese market in the future.

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A Study on the Shallow Marine Site Survey using Seismic Reflection and Refraction Method (탄성파 반사법 및 굴절법을 이용한 천해저 지반조사에 대한 연구)

  • Shin, Sung-Ryul;Kim, Chan-Su;Jo, Churl-Hyun
    • Geophysics and Geophysical Exploration
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    • v.11 no.2
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    • pp.109-115
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    • 2008
  • It is very important to estimate the physical properties of survey area and delineate the geological basement in marine site survey for the design of offshore structures. For the purpose of providing high quality data by means of engineering site survey, it is necessary to apply several survey techniques and carry out the integrated interpretation to each other. In this study, we applied single channel seismic reflection method and OBC (Ocean Bottom Cable) type seismic refraction method at shallow marine. We used a dual boomer-single channel streamer as a source-receiver in seismic reflection survey and airgun source-the developed OBC type streamer in seismic refraction survey. We made 24 channels OBC type streamer which has 4m channel interval and each channel is composed of single hydrophone and preamplifier. We tested the field applicability of the proposed method and applied the typical seismic data processing methods to the obtained reflection data in order to enhance the data quality and image resolution. In order to estimate the geological velocity distribution from refraction data, seismic refraction tomography technique was applied. Therefore, we could successfully perform time-depth conversion using the velocity information as an integrated interpretation. The proposed method could provide reliable geologic information such as sediment layer thickness and 3D basement depth map.