• Journal of the Korea Institute of Information and Communication Engineering
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• v.6 no.2
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• pp.323-329
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• 2002

This paper describes an efficient error-compensation technique for designing a low-error truncated Booth multiplier which produces an N-bit output from a two's complement multiplication of two N bit inputs by eliminating the N least-significant bits. Applying the proposed method, a truncated Booth multiplier for area-efficient and low-power applications has been designed, and its performance(truncation error, area) was analyzed. Since the truncated Booth multiplier does not have about half the partial product generators and adders, it results an area reduction of about 35％, compared with no-truncated parallel multipliers. Error analysis shows that the proposed approach reduces the average truncation error by approximately 60％, compared with conventional methods. A 16-b$\times$16-b truncated Booth multiplier core is designed on full-custom style using 0.35-${\mu}{\textrm}{m}$ CMOS technology. It has 3,000 transistors on an area of 330-${\mu}{\textrm}{m}$$\times$262-${\mu}{\textrm}{m}$ and 20-㎽ power dissipation at 3.3-V supply with 200-MHz operating frequency.

• Microbiology and Biotechnology Letters
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• v.13 no.3
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• pp.173-178
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• 1985

Extracellular amylase from tile filtrate of the submerged culture of Ganoderma lucidum was partially purified by ammonium sulfate precipitation and its properties were studied. The optimum pH and temperature of the enzyme activity were 5.5 and 5$0^{\circ}C$. respectively. This enzyme was most stable at pH 5.0 and stable up to 3$0^{\circ}C$, but it lost completely the activity when it was treated at 6$0^{\circ}C$ for 10 min. The enzyme was activated by the addition of M $n^{++}$, $C^{++}$ and C $u^{++}$, but inhibited by H $g^{++}$, A $g^{++}$ And various enzyme inhibitors and chemical reagents did not affect the enzyme activity. The enzyme hydrolyzed the boiled amylaceous polysaccharides, but it hydrolyzed raw starches very slowly. The activation energy of the enzyme for soluble starch was calculated and found to be 7.06 Kcal per mole. The Km values of the enzyme for soluble starch, amylose, amylopectin and glycogen were 0.16, 0.37, 0.19, and 0.16mg/$m\ell$, respectively. Maltose was found to inhibit the enzyme activity and kinetic analysis revealed a competitive type of inhibition.n.n.n.n.n.

• Korean Journal of Organic Agriculture
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• v.9 no.2
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• pp.101-115
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• 2001

Nitrogen applied as fertilizer for crop production is partly absorbed by plant , and the remaining nitrogen in soil might be leached out through complicated processes to the subsoil layer Especially, NO$_3$-N in leachate causes environmental pollution. The purpose of this study was focused on understanding of uptake of nutrients by plants, the behaviors of nutrients in soil and the possibility of leaching loss when nitrogen fertilizer and completely decomposed compost were applied. Lysimeters(Volume 0.15㎥, Diameter 62cm, Height 62.8cm) were installed for collecting leachate in the Jeju volcanic ash soils. Lysimeter study consisted of thirteen treatments : fallow, fallow with weeding, cropping without fertilizer and compost, three N fertilizer soil surface applications(16, 32, 64kg/10a), three N fertilizer and compost soil surface applications(16+800, 32+1600, 64+32kg/10a), two water dissolved N fertilizer applications(16, 32kg/10a), and low and high plant densities. N fertilizer was applied as urea. The growth of com(preceding crop) and potatoes(succeeding crop) and leaching loss were determined during the experimental period. The results obtained were summarized as follows ; With Increased N, pH of leachate tended to decrease and NO$_3$-N concentration of leachate increased. NO$_3$-N leaching loss was remarkably greater in soil from the bare plot without fertilization and the weed control than from plots with medium N rate and was least in the cropping plot without fertilization. NO$_3$-N concentration in leachates from the water dissolved N fertilizer application plots was 64% of that from the soil surface application plots. The concentration of Ca and K ions and the leaching loss of these ions were least from the cropping plot without fertilization and were greatest from bare plots(T1 and T2) without fertilization. The proportion of leaching and residual N in soil increased as N rate increased indicting that higher N rates increase the possibility of N leaching to subsoil layer The proportion of N leaching losses was lower at the low N rate and the high plant density. In future, fertilization prescription which can maximize fertilizer use efficiency and minimize the pollution of ground water will be needed for conserving the environments.

• Bulletin of the Korean Chemical Society
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• v.16 no.6
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• pp.484-489
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• 1995

The synthesis of new bismuth-barium containing members of layered cuprates with 2201 type structure was reported. By solution calorimetry the formation enthalpies for Bi2MLaCuO6.5 (M=Ba, Ba0.5Sr0.5, Sr) were obtained. Crucial influence of partial oxygen pressure and size of lanthanoid on stability of layered cuprates was shown. Electronic states of variable valence atoms were studied by voltammetry of solids.

• Bulletin of the Korean Chemical Society
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• v.16 no.4
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• pp.356-359
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• 1995

The reaction of 5-aryl-2-phenylisoxazolidine-3-thiones with more than 3 equivalents of anhydrous aluminum chloride in benzene at reflux gave N-(p-biphenylyl)-3-aryl-3-phenylpropanothioamides in good yields. It is conceived that the propanothioamides are formed via the formation of the corresponding N-phenyl-3-aryl-3-phenylpropanothiohydroxamic acids.

• Biomolecules & Therapeutics
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• v.31 no.3
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• pp.350-358
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• 2023

Hand-foot-and-mouth disease (HFMD) is a viral infectious disease that occurs in children under 5 years of age. Its main causes are coxsackievirus (CV) and enterovirus (EV). Since there are no efficient therapeutics for HFMD, vaccines are effective in preventing the disease. To develop broad coverage against CV and EV, the development of a bivalent vaccine form is needed. The Mongolian gerbil is an efficient and suitable animal model of EV71 C4a and CVA16 infection used to investigate vaccine efficacy following direct immunization. In this study, Mongolian gerbils were immunized with a bivalent inactivated EV71 C4a and inactivated CVA16 vaccine to test their effectiveness against viral infection. Bivalent vaccine immunization resulted in increased Ag-specific IgG antibody production; specifically, EV71 C4a-specific IgG was increased with medium and high doses and CVA16-specific IgG was increased with all doses of immunization. When gene expression of T cell-biased cytokines was analysed, Th1, Th2, and Th17 responses were found to be highly activated in the high-dose immunization group. Moreover, bivalent vaccine immunization mitigated paralytic signs and increased the survival rate following lethal viral challenges. When the viral RNA content was determined from various organs, all three doses of bivalent vaccine immunization were found to significantly decrease viral amplification. Upon histologic examination, EV71 C4a and CVA16 induced tissue damage to the heart and muscle. However, bivalent vaccine immunization alleviated this in a dose-dependent manner. These results suggest that the bivalent inactivated EV71 C4a/CVA16 vaccine could be a safe and effective candidate HFMD vaccine.

• Journal of Animal Science and Technology
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• v.48 no.6
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• pp.847-860
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• 2006

This study investigated the effects of feeding Charolais steers on diets rich in either n-6 or n-3 polyunsaturated fatty acids (PUFA) and time on feed (TOF) on muscle fatty acid composition and content. Twenty eight steers were fed on ad libitum forage and one of two concentrates varying in the source of fat; soya (high in C18:2 n-6) or whole linseed (high in C18:3 n-3) for either 60 or 90 days in IGER (Institute of Grassland and Environmental Research, UK). The concentrates were fed at approximately 0.73 of total DM intake. TOF influenced carcass weight, conformation and fatness scores, which were higher at 90 v. 60 days (P<0.05). Diet did not affect total fatty acid content of neutral lipid in m. longissimus thoracis but feeding linseed increased total phospholipid fatty acid by approx- imately 15%(P<0.05). Linseed increased the amount and proportion of C18:3 n-3 (P<0.001) and the proportion of CLA (cis-9, trans-11 conjugated linoleic acid), while soya increased the content (P<0.05) and proportion (P<0.001) of C18:2 n-6 in muscle neutral lipid. In muscle phospholipid, linseed significantly increased the amount of CLA, C18:3 n-3 and its longer chain derivatives as well as C14:0, C16:0, C18:0. C18:1 trans and C18:2 n-6. The amount and proportion of C18:2 n-6 and its longer chain C20 derivatives were higher on feeding soya. TOF (90 v. 60 day) increased the content of C14:0, C16:0, C16:1, CLA, C18:1 n-9, C18:2 n-6 and C18:3 n-3 in muscle neutral lipid. The P:S was not affected by diet or TOF. The ratio of C18:2 n-6 : C18:3 n-3 and sum of n-6 : n-3 fatty acids were higher in muscle from animals fed on linseed v. soya (P<0.001). The study indicates that the PUFA composition of beef muscle may be significantly modified by feeding contrasting dietary lipids, soya vs. linseed. Feeding linseed produced a better balance of muscle fatty acids, more in line with current nutritional recommendations with a lower C18:2 n-6:C18:3 n-3 ratio associated with higher muscle content of C18:3 n-3 and C20:5 n-3 and CLA and lower C20:4 n-6.

• Carbon letters
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• v.16 no.3
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• pp.211-214
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• 2015

Bio-imaging and drug carriers for delivery have created a huge demand for crystals. Crystals are fascinating materials that have been grown for a long time but obtaining biocompatible fluorescent crystals is a challenging task. We report on the growth of fluorescent crystals using a carbon dot (C-dot) solution by a hydrothermal process. The crystallization pattern of these C-dots exhibited a unique dendritic structure having a feather-like morphology. The growth temperature and pressure were maintained at 60℃ and 200 mmHg, respectively, for crystal growth. A green fluorescence (under UV light) that was observed in the C-dot solution was retained in the crystals formed from the solution. Cytotoxicity studies on Vero cells revealed the crystals to be extremely biocompatible. These fluorescent crystals are extremely well suited for biomedical and optoelectronic applications.

• The KIPS Transactions:PartA
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• v.10A no.6
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• pp.671-676
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• 2003

In this paper, we proposed a new First Partial product Addition (FPA) architecture with new compressor (or parallel counter) to CSA tree built in the process of adding partial product for improving speed in the fast parallel multiplier to improve the speed of calculating partial product by about 20% compared with existing parallel counter using full Adder. The new circuit reduces the CLA bit finding final sum by N/2 using the novel FPA architecture. A 5.14nS of multiplication speed of the $16{\times}16$ multiplier is obtained using $0.25\mu\textrm{m}$ CMOS technology. The architecture of the multiplier is easily opted for pipeline design and demonstrates high speed performance.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.44 no.5
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• pp.550-553
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• 2011

The proximate, fatty acid and total amino acid compositions of striped jewfish Stereolepis doederleini muscle were studied. The proximate composition was: 76.4% moisture, 19.4% protein, 2.92% lipid, and 1.19% ash. The predominant total lipid fatty acids were 16:0 (18.7%), 18:1n-9 (16.5%), 22:6n-3 (16.0%), 16:1n-7 (8.53%), 20:5n-3 (7.97%) and 18:0 (5.34%). Glutamic acid (17.4%), lysine (10.6%), aspartic acid (10.4%) and leucine (8.27%) were the predominant amino acids in striped jewfish muscle. These food components of striped jewfish were similar to those of costal and reef dwelling fishes such as black rockfish, black sea bream and rock trout, which are common sliced raw fish in Korea. Therefore, these results suggest that striped jewfish may represent a new aquaculture fish species.